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Using small angle scattering (SAS) to structurally characterise peptide and protein self-assembled materials

Guilbaud, J B; Saiani, A

Chemical Society Reviews. 2011;40(3):1200-1210.

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Abstract

In the past 20 years protein and peptide self-assembly has attracted material scientists' interest due to the possibility to exploit such molecular mechanism to create novel biomaterials including hydrogels. One of the main challenges when dealing with "soft'' biological materials is their structural and morphological characterisation. Small angle scattering (SAS) can be a highly complementary tool to microscopy for the characterisation of such materials as it allows the investigation of samples in their wet-state without the need for any sample preparation such as drying and/or freezing. In this tutorial review we introduce briefly the SAS technique to the non-expert and through selected examples from the literature show how SAS can be readily used thanks to existing analytical approaches developed by a number of authors to extract structural information on the self-assembly of peptide and proteins.

Bibliographic metadata

Type of resource:
Content type:
Publication type:
Published date:
Journal title:
ISSN:
Volume:
40
Issue:
3
Start page:
1200
End page:
1210
Total:
11
Pagination:
1200-1210
Digital Object Identifier:
10.1039/c0cs00105h
ISI Accession Number:
ISI:000287585000003
Related website(s):
  • Related website <Go to ISI>://000287585000003
General notes:
  • Guilbaud, Jean-Baptiste Saiani, Alberto
Access state:
Active

Institutional metadata

University researcher(s):

Record metadata

Manchester eScholar ID:
uk-ac-man-scw:124052
Created by:
Saiani, Alberto
Created:
7th June, 2011, 13:46:03
Last modified by:
Saiani, Alberto
Last modified:
8th October, 2014, 03:06:22

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