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- PMID: 21297157
- UKPMCID: 21297157
- DOI: 10.1093/molbev/msr034
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A Large Palindrome With Interchromosomal Gene Duplications in the Pericentromeric Region of the D. melanogaster Y Chromosome.
Méndez-Lago, MarÃa; Bergman, Casey M; de Pablos, Beatriz; Tracey, Alan; Whitehead, Siobhan L; Villasante, Alfredo
Molecular biology and evolution. 2011;28(7):1967-71.
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Full-text held externally
- PMID: 21297157
- UKPMCID: 21297157
- DOI: 10.1093/molbev/msr034
Abstract
The non-recombining Y chromosome is expected to degenerate over evolutionary time, however, gene gain is a common feature of Y chromosomes of mammals and Drosophila. Here, we report that a large palindrome containing interchromosomal segmental duplications is located in the vicinity of the first amplicon detected in the Y chromosome of D. melanogaster. The recent appearance of such amplicons suggests that duplications to the Y chromosome, followed by the amplification of the segmental duplications, are a mechanism for the continuing evolution of Drosophila Y chromosomes.