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Pernicious anemia - genetic insights.

Banka, Siddharth; Ryan, Kate; Thomson, Wendy; Newman, William G

Autoimmunity reviews. 2011;10(8):455-9.

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Abstract

Pernicious anemia (PA) is a complex, autoimmune, multi-factorial disease. Rapid progress has been made in the understanding of susceptibility to a spectrum of other autoimmune diseases through genome wide association studies (GWAS). However, PA has been conspicuous by its absence from this work. Here, we examine the evidence that PA has a significant heritable component through epidemiological evidence and its co-occurrence with other autoimmune diseases. Further, we consider how knowledge of the genetic susceptibility to other autoimmune diseases may provide insight into the etiology of PA.

Bibliographic metadata

Type of resource:
Content type:
Publication type:
Published date:
Journal title:
Abbreviated journal title:
ISSN:
Place of publication:
Netherlands
Volume:
10
Issue:
8
Pagination:
455-9
Digital Object Identifier:
10.1016/j.autrev.2011.01.009
Pubmed Identifier:
21296191
Pii Identifier:
S1568-9972(11)00024-3
Access state:
Active

Institutional metadata

University researcher(s):

Record metadata

Manchester eScholar ID:
uk-ac-man-scw:132923
Created by:
Newman, William
Created:
12th October, 2011, 14:36:23
Last modified by:
Newman, William
Last modified:
10th April, 2013, 20:06:12

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