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- PMID: 15910423
- UKPMCID: 15910423
- DOI: 10.1111/j.1365-3024.2005.00755.x
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ES-62 is unable to modulate Toxoplasma gondii-driven Th1 responses and pathology.
Couper, K N; Chen, W; Houston, K M; Harnett, W; Johnson, L L
Parasite immunology. 2005;27(4):147-50.
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Full-text held externally
- PMID: 15910423
- UKPMCID: 15910423
- DOI: 10.1111/j.1365-3024.2005.00755.x
Abstract
ES-62, a filarial nematode-derived anti-inflammatory immunomodulator, was administered to mice in an attempt to prevent pathology associated with Toxoplasma gondii infection. The nematode product was shown to elevate mitogen and T. gondii-specific IL-10 production but was unable to inhibit Th1 responses. Consequently ES-62 could not prevent Th1 generated immunopathology.
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Place of publication:
England
Volume:
27
Issue:
4
Pagination:
147-50
Digital Object Identifier:
10.1111/j.1365-3024.2005.00755.x
Pubmed Identifier:
15910423
Pii Identifier:
PIM755
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Active
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Manchester eScholar ID:
uk-ac-man-scw:158626
Created by:
Couper, Kevin
Created:
6th April, 2012, 11:18:31
Last modified by:
Couper, Kevin
Last modified:
14th February, 2016, 20:21:03