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Daptomycin Structure and Mechanism of Action Revealed.
J. Micklefield*
Chemistry & Biology. 2004;11:887-888.
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Abstract
A review. Daptomycin kills otherwise antibiotic-resistant gram-pos. pathogens and is the first lipopeptide antibiotic to reach the clinic. Elucidation of its 3D structure and mechanism of action, reported in this issue of Chem. & Biol. , will facilitate the design and engineering of new, potentially life-saving antibiotics. [on SciFinder (R)]
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