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- DOI: 10.1002/ana.20342
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Essential language function of the right hemisphere in brain tumor patients
Thiel A, Habedank B, Winhuisen L, Herholz KG, Kessler J, Haupt W F, Heiss W D
Annals of Neurology. 2005;57(1):128-131.
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Full-text held externally
- DOI: 10.1002/ana.20342
Abstract
Department of Neurology, University of Cologne, Cologne, Germany. A.Thiel@pet.mpin-koeln.mpg.deNeuroimaging studies of language networks in patients with brain lesions of the left language-dominant hemisphere have shown activation in the right inferior frontal gyrus (IFG). We tested the functional relevance of right IFG activation using neuroimaging-guided repetitive transcranial magnetic stimulation (rTMS) to disturb language function over bilateral IFG in right-handed patients with brain tumors and controls. All subjects were susceptible to TMS over the left IFG. In patients, this susceptibility correlated with left-sided the degree of language lateralization to the left. Those patients with lowest dominance were also susceptible to right-sided TMS proving relevant language function of the right IFG.PMID: 15622534 [PubMed - indexed for MEDLINE]