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Essential language function of the right hemisphere in brain tumor patients

Thiel A, Habedank B, Winhuisen L, Herholz KG, Kessler J, Haupt W F, Heiss W D

Annals of Neurology. 2005;57(1):128-131.

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Abstract

Department of Neurology, University of Cologne, Cologne, Germany. A.Thiel@pet.mpin-koeln.mpg.deNeuroimaging studies of language networks in patients with brain lesions of the left language-dominant hemisphere have shown activation in the right inferior frontal gyrus (IFG). We tested the functional relevance of right IFG activation using neuroimaging-guided repetitive transcranial magnetic stimulation (rTMS) to disturb language function over bilateral IFG in right-handed patients with brain tumors and controls. All subjects were susceptible to TMS over the left IFG. In patients, this susceptibility correlated with left-sided the degree of language lateralization to the left. Those patients with lowest dominance were also susceptible to right-sided TMS proving relevant language function of the right IFG.PMID: 15622534 [PubMed - indexed for MEDLINE]

Bibliographic metadata

Type of resource:
Content type:
Publication type:
Publication form:
Published date:
Journal title:
ISSN:
Volume:
57(1)
Start page:
128
End page:
131
Pagination:
128-131
Digital Object Identifier:
10.1002/ana.20342
Access state:
Active

Record metadata

Manchester eScholar ID:
uk-ac-man-scw:1d10908
Created:
29th August, 2009, 15:47:00
Last modified:
27th September, 2010, 10:17:06

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