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Calcium-activated potassium channels and the regulation of vascular tone.
Ledoux J, Werner ME, Brayden J, Nelson MT
Physiology (Review). 2006;21:69-78.
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Abstract
Different calcium signals in the endothelium and smooth muscle target different types of Ca2+-sensitive K+ channels to modulate vascular function. These differential calcium signals and targets represent multilayered opportunities for prevention and/or treatment of vascular dysfunctions.
Keyword(s)
Animals; Blood Pressure; Humans; Signal Transduction; classification: Potassium Channels, Calcium-Activated; physiology: Calcium; physiology: Endothelium, Vascular; physiology: Muscle, Smooth, Vascular; physiopathology: Cardiovascular Diseases