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The beta1 subunit of the Ca2+-sensitive K+ channel protects against hypertension.

Nelson MT, Bonev A

Journal of Clinical Investigation. 2004;113( 7):955-7.

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Abstract

Previous animal studies have demonstrated that the loss of the beta(1) subunit of the large-conductance Ca(2+)-activated K(+) (BK) channel leads to hypertension. A new study demonstrates that a gain in beta(1) subunit function is associated with protection against diastolic hypertension in humans, underscoring the importance of the beta(1) subunit and the BK channel in the regulation of vascular resistance.

Bibliographic metadata

Type of resource:
Content type:
Publication type:
Publication form:
Author list:
Published date:
ISSN:
Place of publication:
United States
Volume:
113( 7)
Start page:
955
End page:
7
Pagination:
955-7
Access state:
Active

Institutional metadata

University researcher(s):

Record metadata

Manchester eScholar ID:
uk-ac-man-scw:1d16367
Created:
30th August, 2009, 13:55:55
Last modified:
3rd March, 2010, 17:04:42

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