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Epithelial stem cells in the mammary gland: Casting light into dark corners.

Anderson E, Clarke RB

Breast Cancer Res. 1999;1:11-13.

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Abstract

The epithelial structures of the human breast or the mouse mammary gland are derived from a relatively small number of multipotent, tissue-specific stem cells, of which we are surprisingly ignorant. We do not know how many are required to produce a complete mammary gland, how many times they divide during the process, where they are situated in the gland, or even what they look like. We want to know the answers to these questions, not just to satisfy intellectual curiosity, but also because the answers may shed light on the evolution of breast cancer. Now, studies carried out by Kordon and Smith at the National Cancer Institute have pointed the way toward a new understanding of mammary stem cells and their progeny.

Bibliographic metadata

Type of resource:
Content type:
Publication type:
Publication form:
Author list:
Published date:
Journal title:
Place of publication:
1
Volume:
1
Start page:
11
End page:
13
Pagination:
11-13
ISI Accession Number:
11250675
General notes:
  • Journal Article
Access state:
Active

Institutional metadata

University researcher(s):

Record metadata

Manchester eScholar ID:
uk-ac-man-scw:1d2647
Created:
28th August, 2009, 22:13:46
Last modified:
3rd March, 2010, 11:13:24

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