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Thermogenic effects of thyrotrophin-releasing hormone and its analogues in the rat.

Griffiths E, Rothwell NJ, Stock M

Experientia. 1988;44( 1):40-2.

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Abstract

Acute or chronic injection of RX 77,368 (a TRH analogue; 1 mg/kg s.c.) stimulated oxygen consumption (VO2) and brown adipose tissue activity in the rat, and decreased weight gain. Other TRH analogues (CG 3509, RGH 2202) and TRH itself also stimulated VO2. These thermogenic actions are probably mediated centrally by stimulation of sympathetic outflow to brown fat.

Bibliographic metadata

Type of resource:
Content type:
Publication type:
Published date:
Journal title:
ISSN:
Place of publication:
SWITZERLAND
Volume:
44( 1)
Start page:
40
End page:
2
Pagination:
40-2
Access state:
Active

Institutional metadata

University researcher(s):
Academic department(s):

Record metadata

Manchester eScholar ID:
uk-ac-man-scw:1d28970
Created:
2nd September, 2009, 11:41:50
Last modified:
29th March, 2011, 13:10:57

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