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A template-based mnemonic for monoamine oxidase (MAO-N) catalyzed reactions and its application to the chemo-enzymatic deracemisation of the alkaloid (+/-)-crispine A

Bailey, K R; Ellis, A J; Reiss, R; Snape, T J; Turner, N J

Chemical Communications. 2007;(35):3640-3642.

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Abstract

A template-based mnemonic has been developed for the enzyme monoamine oxidase from Aspergillus niger and has been used to successfully identify the alkaloid (+/-)-crispine A as a target for chemo-enzymatic deracemisation yielding the biologically active (R)-enantiomer in 97% e.e.

Bibliographic metadata

Content type:
Publication type:
Publication form:
Published date:
Language:
english
Journal title:
Abbreviated journal title:
ISSN:
Issue:
35
Start page:
3640
End page:
3642
Total:
3
Pagination:
3640-3642
Digital Object Identifier:
10.1039/b710456a
ISI Accession Number:
ISI:000249130000018
General notes:
  • Bailey, Kevin R. Ellis, Andrew J. Reiss, Renate Snape, Timothy J. Turner, Nicholas J. 17 ROYAL SOC CHEMISTRY CAMBRIDGE 205QP
Access state:
Active

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Record metadata

Manchester eScholar ID:
uk-ac-man-scw:1f767
Created:
7th September, 2009, 15:13:15
Last modified:
7th September, 2009, 15:13:15

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