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An Investigation Into Motion Correction Schemes For High Resolution 3D PET And PET/CT
[Thesis]. Manchester, UK: The University of Manchester; 2014.
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Abstract
Although motion correction in medical imaging is well established and has attracted much interest and research funding, a gap still exists in that there is a lack of reliable, low-cost hardware to enable such techniques to be widely adopted in healthcare. Motion correction of brain Positron Emission Tomography (PET) data for instance is an important step in realising the potential offered by modern high resolution PET scanners. Since it is not likely that subjects can remain stationary throughout the PET scan, which can last 60 minutes or more, accurate and reliable motion tracking is needed to correct the PET data for any observed motion. A commercially available marker based motion tracking system was evaluated and found to produce unreliable data. This was due to the possibility of the tracking tool slipping from the subject. This thesis describes the investigations into alternative and novel tracking techniques for use in PET. These included a markerless tracking system using the Microsoft Kinect (a low cost depth sensor) as well as a multiple target marker tracking system. The performance characteristics of both systems (low cost, high spatial and temporal accuracy, and real-time operation) were evaluated using phantom and clinical experiments. Investigations into using these two tracking techniques in whole body PET, specifically measuring the respiratory rate during lung imaging, were developed and compared against current commercially available solutions.
Layman's Abstract
Although motion correction in medical imaging is well established and has attracted much interest and research funding, a gap still exists in that there is a lack of reliable, low-cost hardware to enable such techniques to be widely adopted in healthcare. Motion correction of brain Positron Emission Tomography (PET) data for instance is an important step in realising the potential offered by modern high resolution PET scanners. Since it is not likely that subjects can remain stationary throughout the PET scan, which can last 60 minutes or more, accurate and reliable motion tracking is needed to correct the PET data for any observed motion. A commercially available marker based motion tracking system was evaluated and found to produce unreliable data. This was due to the possibility of the tracking tool slipping from the subject. This thesis describes the investigations into alternative and novel tracking techniques for use in PET. These included a markerless tracking system using the Microsoft Kinect (a low cost depth sensor) as well as a multiple target marker tracking system. The performance characteristics of both systems (low cost, high spatial and temporal accuracy, and real-time operation) were evaluated using phantom and clinical experiments. Investigations into using these two tracking techniques in whole body PET, specifically measuring the respiratory rate during lung imaging, were developed and compared against current commercially available solutions.