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- PMID: 22812533
- UKPMCID: 22812533
- DOI: 10.3109/09546634.2012.713460
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Unmasking of axial spondyloarthritis and oligoarthritis following discontinuation of tumour necrosis factor inhibitor therapy for psoriasis.
Foulkes, Amy C; Griffiths, Christopher E M; Chinoy, Hector; Warren, Richard B
The Journal of dermatological treatment. 2014;25(1):61-2.
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Full-text held externally
- PMID: 22812533
- UKPMCID: 22812533
- DOI: 10.3109/09546634.2012.713460
Abstract
Psoriatic arthritis remains a common cause of morbidity in patients with psoriasis. Little is known about the natural history of the disease and dermatologists do not consistently screen for its presence. We describe a patient with severe psoriasis where long-term biologic therapy with a tumour necrosis factor inhibitor was interrupted for clinical reasons, leading to a rapidly evolving axial spondyloarthritis and oligoarthritis. This unusual presentation of psoriatic arthritis may reflect masking of the disease by long-term treatment with a tumour necrosis factor inhibitor. We advocate the use of screening for psoriatic arthritis, including before and during treatment with biologic therapies.