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- DOI: 10.1039/C5OB01652E
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Helical peptaibol mimics are better ionophores when racemic than when enantiopure
Pike, S.J.; Jones, J.E.; Raftery, J.; Clayden, J.; Webb, S.J
Organic & Biomolecular Chemistry. 2015;13(37):9580-9584.
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Full-text held externally
- DOI: 10.1039/C5OB01652E
Abstract
Helical peptide foldamers rich in α-aminoisobutyric acid (Aib) act as peptaibol-mimicking ionophores in the phospholipid bilayers of artificial vesicles. Racemic samples of these foldamers are more active than their enantiopure counterparts, which was attributed to differing propensities to form aggregates with crystal-like features in the bilayer.
Bibliographic metadata
Type of resource:
Content type:
Publication status:
Published
Publication type:
Publication form:
Published date:
Accepted date:
2015-08-21
Language:
eng
Journal title:
Abbreviated journal title:
ISSN:
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Volume:
13
Issue:
37
Start page:
9580
End page:
9584
Total:
4
Pagination:
9580-9584
Digital Object Identifier:
10.1039/C5OB01652E
Funding awarded to University:
- BBSRC - RESBBSRC
Research data access statement included:
No
Attached files embargo period:
Immediate release
Attached files release date:
7th September, 2015
Access state:
Active
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Record metadata
Manchester eScholar ID:
uk-ac-man-scw:272327
Created by:
Webb, Simon
Created:
7th September, 2015, 13:15:24
Last modified by:
Bentley, Hazel
Last modified:
30th October, 2015, 14:39:03