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Prospective change in daily walking over 2 years in older adults with or at risk of knee osteoarthritis: the MOST study.

White, D K; Tudor-Locke, C; Zhang, Y; Niu, J; Felson, D T; Gross, K D; Nevitt, M C; Lewis, C E; Torner, J; Neogi, T

Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society. 2016;24(2):246-253.

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Abstract

OBJECTIVE: Radiographic disease and knee pain are thought to decrease physical activity in people with knee osteoarthritis (OA), but this has not been formally studied. We examined change in objectively measured daily walking over 2 years and evaluated the association of certain risk factors with reduced walking among adults with or at risk of knee OA. DESIGN: Steps/day over 7 days were collected at baseline and 2 years later in subjects with or at risk of knee OA from the Multicenter Osteoarthritis Study using a StepWatch. We evaluated the presence of radiographic knee osteoarthritis (ROA), knee pain, worsening of ROA and pain over 2 years, obesity, depressive symptoms, living situation, catastrophizing, fatigue, widespread pain and comorbidities with 2-year change in daily walking using regression models adjusted for potential confounders. RESULTS: 1318 met inclusion criteria (age 66.9 ± 7.7, 59% women, BMI 30.6 ± 5.9) and walked 126 ± 1700 steps/day fewer steps at 2 years (95% CI [-218, -35]). People with depressive symptoms at baseline walked 455 fewer steps/day [-872, -68], and there was a trend for people with ROA worsening to walk 183 fewer steps/day [-377.5, 11.7]. No other factors met statistical significance for change in daily walking. CONCLUSION: Adults with or at risk of knee OA experienced only minimal declines in daily walking over 2 years. Nonetheless, depressive symptoms and may be worsening ROA are associated with a decline in steps/day in adults with or at risk of knee OA.

Bibliographic metadata

Type of resource:
Content type:
Publication status:
Published
Publication type:
Publication form:
Published date:
Abbreviated journal title:
ISSN:
Volume:
24
Issue:
2
Start page:
246
End page:
253
Total:
7
Pagination:
246-253
Digital Object Identifier:
10.1016/j.joca.2015.08.004
Pubmed Identifier:
26318659
Pii Identifier:
S1063-4584(15)01287-X
Attached files embargo period:
Immediate release
Attached files release date:
25th January, 2016
Access state:
Active

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Academic department(s):

Record metadata

Manchester eScholar ID:
uk-ac-man-scw:273160
Created by:
Ingram, Mary
Created:
18th September, 2015, 15:50:28
Last modified by:
Ingram, Mary
Last modified:
25th January, 2016, 13:29:33

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