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    Depression in older persons with versus without vascular disease in the open population: similar depressive symptom patterns, more disability.

    Licht-Strunk, Els; Bremmer, Marijke A; {Van Marwijk}, Harm W J; Deeg, Dorly J H; Hoogendijk, Witte J G; {De Haan}, Marten; {Van Tilburg}, Willem; Beekman, Aartjan T F

    Journal of Affective Disorders. 2004;83:155-160.

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    Abstract

    BACKGROUND: Clinical studies suggest that vascular depression presents with typical symptom patterns. The aim of the present study is to examine whether depressed older persons in the open population with and without vascular disease show different symptom patterns. METHODS: In the Longitudinal Aging Study Amsterdam (LASA), a depressed cohort with (n=114) and without (n=292) vascular disease was identified. Depression was measured using self-reports (CES-D). Vascular disease was confirmed or ruled out using a combination of self-reported data, medication use and reports from general practitioners. RESULTS: No significant differences were found in depressive symptom patterns, in symptom clusters nor individual items of the CES-D. Depressed subjects with vascular disease showed much more disability than those without vascular disease. Age of onset of depression did not show statistically significant difference. CONCLUSIONS: From our study in the open population, there is no evidence to support the hypothesis that depressed older persons with vascular disease have a distinct depressive symptom profile, but they do show more disability.

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    Manchester eScholar ID:
    uk-ac-man-scw:280774
    Created by:
    Van Marwijk, Harm
    Created:
    1st December, 2015, 11:22:51
    Last modified by:
    Van Marwijk, Harm
    Last modified:
    1st December, 2015, 11:22:51

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