Related resources
Full-text held externally
- PMID: 19492070
- UKPMCID: 19492070
- DOI: 10.1016/j.ddmec.2008.04.004
Search for item elsewhere
University researcher(s)
Academic department(s)
Skin as an endocrine organ: implications for its function.
Slominski, Andrzej; Wortsman, Jacobo; Paus, Ralf; Elias, Peter M; Tobin, Desmond J; Feingold, Kenneth R
Drug discovery today. Disease mechanisms. 2008;5(2):137-144.
Access to files
Full-text and supplementary files are not available from Manchester eScholar. Full-text is available externally using the following links:
Full-text held externally
- PMID: 19492070
- UKPMCID: 19492070
- DOI: 10.1016/j.ddmec.2008.04.004
Abstract
Described as the body's largest organ, the skin is strategically located at the interface with the external environment where it has evolved to detect, integrate and respond to a diverse range of stressors. A flurry of recent findings has established the skin as an important peripheral (neuro)endocrine organ that is tightly networked to central stress axes. This capability is contributing to the maintenance of body homeostasis, and in this way could be harnessed for therapeutic strategies.