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Skin as an endocrine organ: implications for its function.

Slominski, Andrzej; Wortsman, Jacobo; Paus, Ralf; Elias, Peter M; Tobin, Desmond J; Feingold, Kenneth R

Drug discovery today. Disease mechanisms. 2008;5(2):137-144.

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Abstract

Described as the body's largest organ, the skin is strategically located at the interface with the external environment where it has evolved to detect, integrate and respond to a diverse range of stressors. A flurry of recent findings has established the skin as an important peripheral (neuro)endocrine organ that is tightly networked to central stress axes. This capability is contributing to the maintenance of body homeostasis, and in this way could be harnessed for therapeutic strategies.

Bibliographic metadata

Content type:
Published date:
Language:
eng
Abbreviated journal title:
ISSN:
Volume:
5
Issue:
2
Pagination:
137-144
Digital Object Identifier:
10.1016/j.ddmec.2008.04.004
Pubmed Identifier:
19492070
Access state:
Active

Institutional metadata

University researcher(s):

Record metadata

Manchester eScholar ID:
uk-ac-man-scw:39253
Created by:
Paus, Ralf
Created:
8th October, 2009, 10:21:03
Last modified by:
Paus, Ralf
Last modified:
3rd March, 2010, 18:31:04

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