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- PMID: 20096159
- UKPMCID: 20096159
- DOI: 10.1016/S0001-7310(09)73375-7
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Future therapeutic directions for the treatment of psoriasis.
Actas Dermosifiliogr. 2009;100 Suppl 2:28-31.
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Full-text held externally
- PMID: 20096159
- UKPMCID: 20096159
- DOI: 10.1016/S0001-7310(09)73375-7
Abstract
The future management of psoriasis will depend on a number of distinct but ultimately inter-related strands of evidence, these are: (i) the interplay of genes and environment and the characterisation of psoriasis phenotypes; (ii) the role of pharmacogenetics in personalised healthcare; (iii) the translation of basic scientific discovery of relevant immune and angiogenic pathways into targeted biologic and small molecule therapies; and (iv) the recognition that the management of any chronic disease is enhanced by an understanding of psychosocial issues. A reductionist approach to development of new therapies will be paramount but serendipity and the prepared mind will contribute, as they have always done.