Dalton, L., Kamarashev, J., Ramirez, I., White, G., Malliri, A. & Hurlstone, A (2013). Constitutive Rac Activation is not Sufficient to Initiate Melanocyte Neoplasia but Accelerates Malignant Progression. J Invest Dermatol, eScholarID:185968 | PMID:23337888 | DOI:10.1038/jid.2013.23
Smith, M., Ferguson, J., Arozarena, I., Hayward, R., Marais, R., Chapman, A., Hurlstone, A. & Wellbrock, C (2013). Effect of SMURF2 Targeting on Susceptibility to MEK Inhibitors in Melanoma. J Natl Cancer Inst, 105(1), 33-46. eScholarID:185969 | PMID:23250956 | DOI:10.1093/jnci/djs471
2012
Goonesinghe, A., Luan, X., Hurlstone, A. & Garrod, D (2012). Desmosomal cadherins in zebrafish epiboly and gastrulation. BMC Dev Biol, 12, 1. eScholarID:160124 | PMID:22235774 | DOI:10.1186/1471-213X-12-1
Ramirez, I., Pietka, G., Jones, D., Divecha, N., Alia, A., Baraban, S., Hurlstone, A. & Lowe, M (2012). Impaired neural development in a zebrafish model for Lowe syndrome. Hum Mol Genet, 21(8), 1744-59. eScholarID:160126 | PMID:22210625 | DOI:10.1093/hmg/ddr608
2011
Haud N, Kara F, Diekmann S, Henneke M, Willer JR, Hillwig MH, Gregg RB, MacIntosh GC., Gärtner J, Alia A, and Hurlstone A. (2011). RNase T2 mutant zebrafish model familial cystic leukoencephalopathy and reveal a role for RNase T2 in degrading ribosomal RNA. PNAS, 108(3), 1099-1103. eScholarID:95577 | DOI:10.1073/pnas.1009811107
Kelly, A. & Hurlstone, A (2011). The use of RNAi technologies for gene knockdown in zebrafish. Brief Funct Genomics, 10(4), 189-96. eScholarID:147840 | PMID:21525144 | DOI:10.1093/bfgp/elr014
2010
Wellbrock C and Hurlstone A. (2010). BRAF as therapeutic target in melanoma. Biochemical Pharmacology, eScholarID:76638
Kabli S, He S, Spaink HP, Hurlstone A, Snaar Jagalska E, De Groot HJM, and Alia A. (2010). In Vivo Magnetic Resonance Imaging to Detect Malignant Melanoma in Adult Zebrafish. Zebrafish, 7(2), 143-148. eScholarID:76636 | DOI:10.1089/zeb.2009.0649
Santoriello C, Gennaro E, Anelli V, Distel M, Kelly A, Köster RW, Hurlstone A, and Mione MC. (2010). Kita driven expression of oncogenic HRAS leads to early onset and highly penetrant melanoma in zebrafish. PLoS ONE, 5(21), e15170. eScholarID:95579 | DOI:10.1371/journal.pone.0015170
Feng Y, Santoriello C, Mione M, Hurlstone A, and Martin P. (2010). Live imaging of innate immune cell sensing of transformed cells in zebrafish larvae: parallels between tumor initiation and wound inflammation. PLoS Biology, 8(12), e1000562. eScholarID:95578 | DOI:10.1371/journal.pbio.1000562
Nicoli S, Standley C, Walker P, Hurlstone A, Fogarty KE, and Lawson ND. (2010). microRNA-mediated integration of haemodynamics and Vegf signaling during angiogenesis. Nature, 464(7292), 1196-1200. eScholarID:76634 | DOI:10.1038/nature08889
2009
Michailidou CM, Jones M, Walker P, Kamarashev J, Kelly A, Hurlstone A. (2009). Dissecting the roles of Raf- and PI3k-signalling pathways in melanoma formation and progression in a zebrafish model. Disease Models and Mechanisms, 2(7/8), eScholarID:1c8472 | DOI:10.1242/dmm.001149
2008
Chen, J. & Hurlstone, A (2008). Targeted and Conditional Gene Expression Workshop, 8th International Conference on Zebrafish Development and Genetics. Zebrafish, 5(3), 193-195. eScholarID:160125 | PMID:20798783 | DOI:10.1089/zeb.2008.0543
2007
Muncan V, Faro A, Haramis AP, Hurlstone AF, Wienholds E, van Es J, Korving J, Begthel H, Zivkovic D, Clevers H. (2007). T-cell factor 4 (Tcf7l2) maintains proliferative compartments in zebrafish intestine. EMBO reports, 8(10), 966-73. eScholarID:1c6979 | PMID:17823612 | DOI:10.1038/sj.embor.7401071
2006
Garin G, Zibara K, Aguilar F, Lo M, Hurlstone A, Poston R, McGregor JL. (2006). 6A3-5/Osa2 is an Early Activated Gene Implicated in the Control of Vascular Smooth Muscle Cell Functions. Journal of biomedicine & biotechnology, 2006(5), 97287. eScholarID:1c6980 | PMID:17489020 | DOI:10.1155/JBB/2006/97287
Haramis AP, Hurlstone A, van der Velden Y, Begthel H, van den Born M, Offerhaus GJ, Clevers HC. (2006). Adenomatous polyposis coli-deficient zebrafish are susceptible to digestive tract neoplasia. EMBO reports, 7(4), 444-9. eScholarID:1c6981 | PMID:16439994 | DOI:10.1038/sj.embor.7400638
Mould AP, McLeish JA, Huxley-Jones J, Goonesinghe AC, Hurlstone AF, Boot-Handford RP, Humphries MJ. (2006). Identification of multiple integrin beta1 homologs in zebrafish (Danio rerio). BMC cell biology [electronic resource], 7, 24. eScholarID:1c5345 | PMID:16787535 | DOI:10.1186/1471-2121-7-24
Malliri A, Rygiel TP, van der Kammen RA, Song J-Y, Engers R, Hurlstone AFL, Clevers H, and John G Collard. (2006). The Rac activator Tiam1 is a Wnt-responsive gene that modifies intestinal tumour development. Journal of Biological Chemistry, 281, 543-548. eScholarID:1c4370 | DOI:10.1074/jbc.M507582200
2004
Giraud S, Hurlstone A, Avril S, Coqueret O. (2004). Implication of BRG1 and cdk9 in the STAT3-mediated activation of the p21waf1 gene. Oncogene, 23(44), 7391-7398. eScholarID:1c2609 | DOI:10.1038/sj.onc.1207972
2003
Garin G, Badid C, McGregor B, Vincent M, Guerret S, Zibara K, Hurlstone A, Laville M, McGregor JL. (2003). Ischemia induces early expression of a new transcription factor (6A3-5) in kidney vascular smooth muscle cells: studies in rat and human renal pathology. The American journal of pathology, 163(6), 2485-94. eScholarID:1c6982 | PMID:14633620 | DOI:10.1016/S0002-9440(10)63603-6
Hurlstone A.F., Haramis A.P., Wienholds E., Begthel H., Korving J., Van Eeden F., Cuppen E., Zivkovic D., Plasterk R.H., Clevers H. (2003). The Wnt/beta-catenin pathway regulates cardiac valve formation. Nature, 425, 633-637. eScholarID:1c2404 | DOI:10.1038/nature02028
2002
Hurlstone AF, Olave IA, Barker N, van Noort M, Clevers H. (2002). Cloning and characterization of hELD/OSA1, a novel BRG1 interacting protein. The Biochemical journal, 364(Pt 1), 255-64. eScholarID:1c6984 | PMID:11988099
Hurlstone A., Clevers H. (2002). T-cell factors: turn-ons and turn-offs. The EMBO journal, 21, 2303-2311. eScholarID:1c2402 | DOI:10.1093/emboj/21.10.2303
van de Wetering M, Sancho E, Verweij C, de Lau W, Oving I, Hurlstone A, van der Horn K, Batlle E, Coudreuse D, Haramis AP, Tjon-Pon-Fong M, Moerer P, van den Born M, Soete G, Pals S, Eilers M, Medema R, Clevers H. (2002). The beta-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells. Cell, 111(2), 241-50. eScholarID:1c6983 | PMID:12408868 | DOI:10.1016/S0092-8674(02)01014-0
2001
Hughes K.A., Hurlstone A.F., Tobias E.S., McFarlane R., Black D.M. (2001). Absence of ST7 mutations in tumor-derived cell lines and tumors. Nat.Genet, 29, 380-381. eScholarID:1c2401 | DOI:10.1038/ng783
Tobias E.S., Hurlstone A.F., MacKenzie E., McFarlane R., Black D.M. (2001). The TES gene at 7q31.1 is methylated in tumours and encodes a novel growth-suppressing LIM domain protein. Oncogene, 20, 2844-2853. eScholarID:1c2405 | DOI:10.1038/sj.onc.1204433
Barker N., Hurlstone A., Musisi H., Miles A., Bienz M., Clevers H. (2001). The chromatin remodelling factor Brg-1 interacts with beta-catenin to promote target gene activation. The EMBO journal, 20(17), 4935-4943. eScholarID:1c2400 | DOI:10.1093/emboj/20.17.4935
1999
Hurlstone A.F., Reid G., Reeves J.R., Fraser J., Strathdee G., Rahilly M., Parkinson E.K., Black D.M. (1999). Analysis of the CAVEOLIN-1 gene at human chromosome 7q31.1 in primary tumours and tumour-derived cell lines. Oncogene, 18, 1881. eScholarID:1c2403 | DOI:10.1038/sj.onc.1202491
1998
Hurlstone A, Black DM. (1998). Prostate cancer: new therapies in the pipeline? Current biology, 8(12), eScholarID:1c6986 | PMID:9637916
Malliri A, Symons M, Hennigan RF, Hurlstone AF, Lamb RF, Wheeler T, Ozanne BW. (1998). The transcription factor AP-1 is required for EGF-induced activation of rho-like GTPases, cytoskeletal rearrangements, motility, and in vitro invasion of A431 cells. The Journal of cell biology, 143(4), 1087-99. eScholarID:1c6985 | PMID:9817764
