The development of methods for the proteomic analysis of integrin adhesion complexes.
Multicellular existence relies on the engagement of integrin cell surface receptors with the extracellular matrix (ECM) and counter-receptors on adjacent cells. Integrins are a family of 24 heterodimers that result from selective noncovalent associations of 18 alpha and 8 beta subunits.
In the laboratory of Professor Martin Humphries we are developing quantitative proteomic methodologies suitable for the analysis of transmembrane receptor-ligand complexes.
Personal details | Research | Publications
This website will look much better in a web browser that supports web standards, but it is accessible to any browser or Internet device.