Nordberg, A., Carter, S., Rinne, J., Drzezga, A., Brooks, D., Vandenberghe, R., Perani, D., Forsberg, A., Långström, B., Scheinin, N., Karrasch, M., Någren, K., Grimmer, T., Miederer, I., Edison, P., Okello, A., Laere, K., Nelissen, N., Vandenbulcke, M., Garibotto, V., Almkvist, O., Kalbe, E., Hinz, R. & Herholz, K (2013). A European multicentre PET study of fibrillar amyloid in Alzheimer’s disease. European Journal of Nuclear Medicine and Molecular Imaging, 40(1), 104-114. eScholarID:185076 | DOI:10.1007/s00259-012-2237-2
Yeh, H., Tian, M., Hinz, R., Young, D., Shavrin, A., Mukhapadhyay, U., Flores, L., Balatoni, J., Soghomonyan, S., Jeong, H., Pal, A., Uthamanthil, R., Jackson, J., Nishii, R., Mizuma, H., Onoe, H., Kagawa, S., Higashi, T., Fukumitsu, N., Alauddin, M., Tong, W., Herholz, K. & Gelovani, J (2013). Imaging epigenetic regulation by histone deacetylases in the brain using PET/MRI with (18)F-FAHA. Neuroimage, 64, 630-9. eScholarID:185077 | DOI:10.1016/j.neuroimage.2012.09.019 S1053-8119(12)00929-9 [pii]
2012
Bohnen, N., Djang, D., Herholz, K., Anzai, Y. & Minoshima, S (2012). Effectiveness and Safety of 18F-FDG PET in the Evaluation of Dementia: A Review of the Recent Literature. J Nucl Med, 53(1), 59-71. eScholarID:153916 | DOI:jnumed.111.096578 [pii] 10.2967/jnumed.111.096578
Caroli, A., Prestia, A., Chen, K., Ayutyanont, N., Landau, S., Madison, C., Haense, C., Herholz, K., Nobili, F., Reiman, E., Jagust, W. & Frisoni, G (2012). Summary Metrics to Assess Alzheimer Disease-Related Hypometabolic Pattern with 18F-FDG PET: Head-to-Head Comparison. J Nucl Med, 53(4), 592-600. eScholarID:168607 | DOI:jnumed.111.094946 [pii] 10.2967/jnumed.111.094946
Carter, S., Caine, D., Burns, A., Herholz, K. & Lambon Ralph, M (2012). Staging of the cognitive decline in Alzheimer's disease: insights from a detailed neuropsychological investigation of mild cognitive impairment and mild Alzheimer's disease. Int J Geriatr Psychiatry, 27(4), 423-32. eScholarID:168617 | DOI:10.1002/gps.2738
Djang, D., Janssen, M., Bohnen, N., Booij, J., Henderson, T., Herholz, K., Minoshima, S., Rowe, C., Sabri, O., Seibyl, J., Van Berckel, B. & Wanner, M (2012). SNM Practice Guideline for Dopamine Transporter Imaging with 123I-Ioflupane SPECT 1.0. J Nucl Med, 53(1), 154-63. eScholarID:153913 | DOI:jnumed.111.100784 [pii] 10.2967/jnumed.111.100784
Haense, C., Kalbe, E., Herholz, K., Hohmann, C., Neumaier, B., Krais, R. & Heiss, W (2012). Cholinergic system function and cognition in mild cognitive impairment. Neurobiol Aging, 33(5), 867-877. eScholarID:168609 | DOI:S0197-4580(10)00363-5 [pii] 10.1016/j.neurobiolaging.2010.08.015
Herholz, K., Langen, K., Schiepers, C. & Mountz, J (2012). Brain Tumors. Seminars in Nuclear Medicine, 42(6), 375-389. eScholarID:168605 | DOI:10.1053/j.semnuclmed.2012.06.001
Herholz, K (2012). Use of FDG PET as an imaging biomarker in clinical trials in Alzheimer's disease. Biomarkers in Medicine, 6(4), 431-439. eScholarID:168611 | DOI:10.2217/bmm.12.51
Marcone, A., Garibotto, V., Moresco, R., Florea, I., Panzacchi, A., Carpinelli, A., Virta, J., Tettamanti, M., Borroni, B., Padovani, A., Bertoldo, A., Herholz, K., Rinne, J., Cappa, S. & Perani, D (2012). [11C]-MP4A PET Cholinergic Measurements in Amnestic Mild Cognitive Impairment, Probable Alzheimer's Disease, and Dementia with Lewy Bodies: A Bayesian Method and Voxel-Based Analysis. J Alzheimers Dis, eScholarID:168606 | DOI:M15528N3T6006287 [pii] 10.3233/JAD-2012-111748
Miller, P., Coope, D., Thompson, G., Jackson, A. & Herholz, K (2012). Quantitative evaluation of white matter tract DTI parameter changes in gliomas using nonlinear registration. Neuroimage, 60(4), 2309-15. eScholarID:168608 | DOI:S1053-8119(12)00210-8 [pii] 10.1016/j.neuroimage.2012.02.033
Nordberg, A., Carter, S., Rinne, J., Drzezga, A., Brooks, D., Vandenberghe, R., Perani, D., Forsberg, A., Langstrom, B., Scheinin, N., Karrasch, M., Nagren, K., Grimmer, T., Miederer, I., Edison, P., Okello, A., Van Laere, K., Nelissen, N., Vandenbulcke, M., Garibotto, V., Almkvist, O., Kalbe, E., Hinz, R. & Herholz, K (2012). A European multicentre PET study of fibrillar amyloid in Alzheimer's disease. Eur J Nucl Med Mol Imaging, eScholarID:173007 | DOI:10.1007/s00259-012-2237-2
Teipel, S., Sperling, R., Skudlarski, P., Jack Jr, C., Hampel, H., Fellgiebel, A. & Herholz, K (2012). MRI- and PET- Based Imaging Markers for the Diagnosis of Alzheimer’s Disease. In Hampel, H. & Carrillo, M. (Ed.), Alzheimer’s Disease – Modernizing Concept, Biological Diagnosis and Therapy. (pp. 80-114). Basel: Karger. eScholarID:168610
2011
Carter, S., Caine, D., Burns, A., Herholz, K. & Lambon Ralph, M (2011). Staging of the cognitive decline in Alzheimer's disease: insights from a detailed neuropsychological investigation of mild cognitive impairment and mild Alzheimer's disease. Int J Geriatr Psychiatry, eScholarID:153912 | DOI:10.1002/gps.2738
Cawthorne, C., Prenant, C., Smigova, A., Julyan, P., Maroy, R., Herholz, K., Rothwell, N. & Boutin, H (2011). Biodistribution, pharmacokinetics and metabolism of interleukin-1 receptor antagonist (IL-1RA) using [(1)F]-IL1RA and PET imaging in rats. Br J Pharmacol, 162(3), 659-72. eScholarID:153915 | DOI:10.1111/j.1476-5381.2010.01068.x
Drake, C., Boutin, H., Jones, M., Denes, A., McColl, B., Selvarajah, J., Hulme, S., Georgiou, R., Hinz, R., Gerhard, A., Vail, A., Prenant, C., Julyan, P., Maroy, R., Brown, G., Smigova, A., Herholz, K., Kassiou, M., Crossman, D., Francis, S., Proctor, S., Russell, J., Hopkins, S., Tyrrell, P., Rothwell, N. & Allan, S (2011). Brain inflammation is induced by co-morbidities and risk factors for stroke. Brain Behav Immun, 25(6), 1113-22. eScholarID:128095 | DOI:S0889-1591(11)00058-4 [pii] 10.1016/j.bbi.2011.02.008
Herholz, K (2011). Amyloid PET: Its diagnostic potential compared to FDG. Medicine Nucleaire, 35, 322-326. eScholarID:128096 | DOI:10.1016/j.mednuc.2011.02.007
Herholz, K. & Ebmeier, K (2011). Clinical amyloid imaging in Alzheimer’s disease. Lancet Neurology, 10, 667-670. eScholarID:128097 | DOI:10.1016/S1474-4422(11)70123-5
Herholz, K (2011). Molecular imaging in Alzheimer's Disease. European Neurological Review, 6(1), 16-20. eScholarID:128098 | DOI:10.1016/j.jalz.2010.05.515
Herholz, K., Westwood, S., Haense, C. & Dunn, G (2011). Evaluation of a calibrated (18)F-FDG PET score as a biomarker for progression in Alzheimer disease and mild cognitive impairment. J Nucl Med, 52(8), 1218-26. eScholarID:134134 | PMID:21764801 | DOI:10.2967/jnumed.111.090902
Kalbe, E., Onur, O., Minnerop, M., Reimann, J., Althaus, A., Ahmadzadehfar, H., Dodel, R., Strach, K., Clemen, C., Herholz, K., Haense, C., Fink, G. & Schroder, R (2011). Early signs of VCP-related frontotemporal dementia: a neuropsychological, FDG-PET and fMRI study. J Neurol, 258(3), 515-8. eScholarID:153914 | DOI:10.1007/s00415-010-5774-2
Markiewicz, P., Matthews, J., Declerck, J. & Herholz, K (2011). Robustness of correlations between PCA of FDG-PET scans and biological variables in healthy and demented subjects. Neuroimage, 56(2), 782-7. eScholarID:128100 | DOI:S1053-8119(10)00800-1 [pii] 10.1016/j.neuroimage.2010.05.066
Merhof, D., Markiewicz, P., Platsch, G., Declerck, J., Weih, M., Kornhuber, J., Kuwert, T., Matthews, J. & Herholz, K (2011). Optimized data preprocessing for multivariate analysis applied to (99m)Tc-ECD SPECT data sets of Alzheimer's patients and asymptomatic controls. J Cereb Blood Flow Metab, 31(1), 371-83. eScholarID:107300 | DOI:10.1038/jcbfm.2010.112
2010
Hampel, H., R. Frank, K. Broich, S. Teipel, R. G. Katz, J. Hardy, K. Herholz, A. L. Bokde, F. Jessen, Y. G. Hoessler, W. R. Sanhai, H. Zetterberg, J. Woodcock and K. Blennow. (2010). Biomarkers for Alzheimer’s disease: academic, industry and regulatory perspectives. Nature Reviews Drug Discovery, 9, 560-574. eScholarID:84161 | DOI:10.1038/nrd3115
Galldiks N, Kracht LW, Berthold F, Miletic H, Klein JC, Herholz KG, Jacobs AH, Heiss WD. (2010). [11C]-L-Methionine Positron Emission Tomography in the Management of Children and Young Adults with Brain Tumours. Journal of Neuro-Oncology, 96(2), 231-239. eScholarID:1d19616 | DOI:10.1007/s11060-009-9953-x
Haense, C., Kalbe, E., Herholz, K., Hohmann, C., Neumaier, B., Krais, R. & Heiss, W (2010). Cholinergic system function and cognition in mild cognitive impairment. Neurobiol Aging, eScholarID:107297 | DOI:10.1016/j.neurobiolaging.2010.08.015
Herholz, K (2010). Cerebral glucose metabolism in preclinical and prodromal Alzheimer's disease. Expert Rev Neurother, 10(11), 1667-73. eScholarID:107296 | DOI:10.1586/ern.10.136
Kalbe, E., Onur, O., Minnerop, M., Reimann, J., Althaus, A., Ahmadzadehfar, H., Dodel, R., Strach, K., Clemen, C., Herholz, K., Haense, C., Fink, G. & Schroder, R (2010). Early signs of VCP-related frontotemporal dementia: a neuropsychological, FDG-PET and fMRI study. J Neurol, eScholarID:107298 | DOI:10.1007/s00415-010-5774-2
Terriere, E., Dempsey, M., Herrmann, L., Tierney, K., Lonie, J., O'Carroll, R., Pimlott, S., Wyper, D., Herholz, K. & Ebmeier, K (2010). 5-(123)I-A-85380 binding to the alpha4beta2-nicotinic receptor in mild cognitive impairment. Neurobiol Aging, 31(11), 1885-93. eScholarID:107295 | DOI:S0197-4580(08)00365-5 [pii] 10.1016/j.neurobiolaging.2008.10.008
Tolboom, N., van der Flier, W., Boverhoff, J., Yaqub, M., Wattjes, M., Raijmakers, P., Barkhof, F., Scheltens, P., Herholz, K., Lammertsma, A. & van Berckel, B (2010). Molecular imaging in the diagnosis of Alzheimer's disease: visual assessment of [11C]PIB and [18F]FDDNP PET images. J Neurol Neurosurg Psychiatry, 81(8), 882-4. eScholarID:107299 | DOI:jnnp.2009.194779 [pii] 10.1136/jnnp.2009.194779
2009
Herholz, K. (2009). Functional imaging with FDG-PET in mild cognitive impairment. Imaging the Aging Brain. In Jagust, W., D'Esposito, M (Ed.), Imaging the Aging Brain. (pp. 183-190). Oxford: Oxford University Press. eScholarID:84157
Ullrich, R. T., L. Kracht, A. Brunn, K. Herholz, P. Frommolt, H. Miletic, M. Deckert, W. D. Heiss and A. H. Jacobs. (2009). Methyl-L-11C-methionine PET as a diagnostic marker for malignant progression in patients with glioma. Journal of Nuclear Medicine, 50(12), 1962-1968. eScholarID:84172 | DOI:10.2967/jnumed.109.065904
Salmon, E, Kerrouche, N, Perani, D, Lekeu, F, Holthoff, V, Beuthien-Baumann, B, Sorbi, S, Lemaire, C, Collette, F, Herholz, KG. (2009). On the multivariate nature of brain metabolic impairment in Alzheimer's disease. Neurobiol Aging, 30(2), 186-197. eScholarID:1d17584 | DOI:10.1016/j.neurobiolaging.2007.06.010
Haense, C., K. Herholz, W. J. Jagust and W. D. Heiss. (2009). Performance of FDG PET for Detection of Alzheimer’s Disease in Two Independent Multicenter Samples (NEST-DD and ADNI). Dementia and Geriatric Cognitive Disorders, 28, 259-266. eScholarID:84158 | DOI:10.1159/000241879
Markiewicz, P. J., J. C. Matthews, J. Declerck and K. Herholz. (2009). Robustness of multivariate image analysis assessed by resampling techniques and applied to FDG-PET scans of patients with Alzheimer's disease. Neuroimage, 46(2), 472-485. eScholarID:84166 | DOI:10.1016/j.neuroimage.2009.01.020
2008
Terrière, E, Dempsey, M, Herrmann, L, Tierney, K, Lonie, J, O'Carroll, R, Pimlott, S, Wyper, D, Herholz, KG, Ebmeier, K. (2008). 5-(123)I-A-85380 binding to the alpha4beta2-nicotinic receptor in mild cognitive impairment. Neurobiol Aging, eScholarID:1d19523 | DOI:10.1016/j.neurobiolaging.2008.10.008
Salmon E, Perani D, Collette F, Feyers D, Kalbe E, Holthoff V, Sorbi S, Herholz KG. (2008). A comparison of unawareness in frontotemporal dementia and Alzheimer's disease. J Neurol Neurosurg Psychiatry, 79( 2), 176-9. eScholarID:1d17583
Herholz KG. (2008). Acetylcholine esterase activity in mild cognitive impairment and Alzheimer's disease. Eur J Nucl Med Mol Imaging, 35 Suppl 1, S25-9. eScholarID:1d17581
Haense CC, Buerger K, Kalbe E, Drzezga A, Teipel S, Markiewicz P, Herholz KG, Heiss W, Hampel H. (2008). CSF total and phosphorylated tau protein, regional glucose metabolism and dementia severity in Alzheimer's disease. Eur J Neurol, 15( 11), eScholarID:1d19521 | DOI:10.1111/j.1468-1331.2008.02274.x
Klein J, Herholz KG, Wienhard K, Heiss W. (2008). Cortical flattening applied to high-resolution 18F-FDG PET. J Nucl Med, 49( 1), 44-9. eScholarID:1d17582
Herholz KG, Weisenbach S, Kalbe E. (2008). Deficits of the cholinergic system in early AD. Neuropsychologia, 46( 6), 1642-7. eScholarID:1d17580
Garibotto, V, Borroni, B, Kalbe, E, Herholz, KG, Salmon, E, Holtoff, V, Sorbi, S, Cappa, S, Padovani, A, Fazio, F, Perani, D. (2008). Education and occupation as proxies for reserve in aMCI converters and AD: FDG-PET evidence. Neurology, 71( 17), eScholarID:1d19520 | DOI:10.1212/01.wnl.0000327670.62378.c0
Mosconi, L, Tsui, W, Herholz, KG, Pupi, A, Drzezga, A, Lucignani, G, Reiman, E, Holthoff, V, Kalbe, E, Sorbi, S, Diehl-Schmid, J, Perneczky, R, Clerici, F, Caselli, R, Beuthien-Baumann, B, Kurz, A, Minoshima, S, de Leon, M. (2008). Multicenter standardized 18F-FDG PET diagnosis of mild cognitive impairment, Alzheimer's disease, and other dementias. J Nucl Med, 49( 3), 390-8. eScholarID:1d17579 | DOI:10.2967/jnumed.107.045385
2007
Coope DJ, Herholz KG, Price PM. (2007). Brain tumours: planning and monitoring therapy with PET. In: Cancer Imaging, Hayat M (ed). Elsevier Science. eScholarID:3d1091
Coope DJ, Cizek J, Eggers C, Vollmar S, Heiss W, Herholz KG. (2007). Evaluation of Primary Brain Tumors Using <sup>11<\sup>C-Methionine PET with Reference to a Normal Methionine Uptake Map. Journal of Nuclear Medicine, 48(12), eScholarID:1d16835
Eggers C, Szelies B, Bauer B, Wienhard K, Schröder H, Herholz KG, Heiss W. (2007). Imaging of acetylcholine esterase activity in brainstem nuclei involved in regulation of sleep and wakefulness. Eur J Neurol, 14( 6), 690-3. eScholarID:1d17585
Vollmar S, Hampl JA, Kracht L, Herholz KG. (2007). Integration of Functional Data (PET) into Brain Surgery Planning and Neuronavigation. Advances in Medical Engineering. Springer. eScholarID:3d951
Herholz KG, Coope DJ, Jackson A. (2007). Metabolic and molecular imaging in neuro-oncology. Lancet Neurology, 6(8), 711-24. eScholarID:1d16060
Herholz KG, Carter S, Jones M. (2007). Positron emission tomography imaging in dementia. Br J Radiol, 80 Spec No 2, S160-7. eScholarID:1d17578
Herting, B, Beuthien-Baumann, B, Pöttrich, K, Donix, M, Triemer, A, Lampe, J, von Kummer, R, Herholz, KG, Reichmann, H, Holthoff, V. (2007). Prefrontal cortex dysfunction and depression in atypical parkinsonian syndromes. Mov Disord, 22( 4), 490-7. eScholarID:1d17587 | DOI:10.1002/mds.21237
Rueger, M, Kracht, L, Hilker, R, Thiel, A, Sobesky, J, Winkeler, A, Thomas, A, Heneka, M, Graf, R, Herholz, KG, Heiss, W, Jacobs, A. (2007). Role of in vivo imaging of the central nervous system for developing novel drugs. Q J Nucl Med Mol Imaging, 51( 2), 164-81. eScholarID:1d17586
2006
Kerrouche N, Herholz KG, Mielke R, Holthoff V, Baron J. (2006). 18FDG PET in vascular dementia: differentiation from Alzheimer's disease using voxel-based multivariate analysis. J Cereb Blood Flow Metab, 26( 9), 1213-21. eScholarID:1d14195
Kracht LW, Herholz KG, Vollmar S, Jacobs AH. (2006). Brain Tumors: Astrocytoma, Oligodendroglioma, and Glioblastoma Images with PET and SPECT. Molecular Anatomic Imaging: PET-CT and SPECT-CT Integrated Modality Imaging Lippincott, eScholarID:1d33052
Herholz KG. (2006). Cognitive dysfunction and emotional-behavioural changes in MS: the potential of positron emission tomography. J Neurol Sci, 245( 1-2), 9-13. eScholarID:1d14194
Eggers C, Herholz KG, Kalbe E, Heiss W. (2006). Cortical acetylcholine esterase activity and ApoE4-genotype in Alzheimer disease. Neurosci Lett, 408( 1), 46-50. eScholarID:1d14191
Salmon, E, Kerrouche, N, Herholz, KG, Perani, D, Holthoff, V, Beuthien-Baumann, B, Degueldre, C, Lemaire, C, Luxen, A, Baron, J, Collette, F, Garraux, G. (2006). Decomposition of metabolic brain clusters in the frontal variant of frontotemporal dementia. Neuroimage, 30( 3), 871-8. eScholarID:1d14197 | DOI:10.1016/j.neuroimage.2005.10.016
Coope DJ, Vollmar S, Eggers C, Herholz KG, Heiss WD. (2006). Development of a normal 11C-methionine PET uptake map: a novel approach to the evaluation of brain tumors using PET [Abstracts for the Seventh Congress of the European Association for Neuro-Oncology (EANO)]. Presented at Seventh Congress of the European Association for Neuro-Oncology. Vienna, Austria. eScholarID:2d2046
Masdeu, J, Irimia, P, Asenbaum, S, Bogousslavsky, J, Brainin, M, Chabriat, H, Herholz, KG, Markus, H, Martínez-Vila, E, Niederkorn, K, Schellinger, P, Seitz, R, NULL. (2006). EFNS guideline on neuroimaging in acute stroke. Report of an EFNS task force. Eur J Neurol, 13( 12), eScholarID:1d21256 | DOI:10.1111/j.1468-1331.2006.01507.x
Thiel A, Habedank B, Herholz KG, Kessler J, Winhuisen L, Haupt W, Heiss W. (2006). From the left to the right: How the brain compensates progressive loss of language function. Brain Lang, 98( 1), 57-65. eScholarID:1d14199
Salmon, E, Perani, D, Herholz, KG, Marique, P, Kalbe, E, Holthoff, V, Delbeuck, X, Beuthien-Baumann, B, Pelati, O, Lespagnard, S, Collette, F, Garraux, G. (2006). Neural correlates of anosognosia for cognitive impairment in Alzheimer's disease. Hum Brain Mapp, 27( 7), 588-97. eScholarID:1d14198 | DOI:10.1002/hbm.20203
Peters, F, Perani, D, Herholz, KG, Holthoff, V, Beuthien-Baumann, B, Sorbi, S, Pupi, A, Degueldre, C, Lemaire, C, Collette, F, Salmon, E. (2006). Orbitofrontal dysfunction related to both apathy and disinhibition in frontotemporal dementia. Dement Geriatr Cogn Disord, 21( 5-6), 373-9. eScholarID:1d14196 | DOI:10.1159/000091898
Herholz KG. (2006). Positron emission tomography (PET) ligands and metabolic brain imaging. Neurodegenerative Diseases. Henry Stewart Talks. eScholarID:3d963
Herholz KG, Morris CM, Perani D. (2006). The dementias: early diagnosis and evaluation. Taylor & Francis. eScholarID:4d156
Galldiks N, Kracht L, Burghaus L, Thomas A, Jacobs A, Heiss W, Herholz KG. (2006). Use of 11C-methionine PET to monitor the effects of temozolomide chemotherapy in malignant gliomas. Eur J Nucl Med Mol Imaging, 33( 5), 516-24. eScholarID:1d14192
2005
Jacobs, A, Thomas, A, Kracht, L, Li, H, Dittmar, C, Garlip, G, Galldiks, N, Klein, J, Sobesky, J, Hilker, R, Vollmar, S, Herholz, KG, Wienhard, K, Heiss, W. (2005). 18F-fluoro-L-thymidine and 11C-methylmethionine as markers of increased transport and proliferation in brain tumors. J Nucl Med, 46( 12), 1948-58. eScholarID:1d14190
Herholz KG. (2005). Action of cholinesterase inhibitors in patients' brains. Journal of Neurology, Neurosurgery and Psychiatry, 76 (3), eScholarID:1d10870
Kalbe E, Salmon E, Perani D, Holthoff V, Sorbi S, Elsner A, Weisenbach S, Brand M, Lenz O, Kessler J, Luedecke S, Ortelli P, Herholz, KG. (2005). Anosognosia in very mild Alzheimer's disease but not in mild cognitive impairment. Dementia & Geriatric Cognitive Disorders, 19, 349-356. eScholarID:1d10912 | DOI:10.1159/000084704
Herholz KG, Weisenbach S, Kalbe E, Diederich N, Heiss W. (2005). Cerebral acetylcholine esterase activity in mild cognitive impairment. Neuroreport, 16( 13), 1431-4. eScholarID:1d14185
Salmon E, Lespagnard S, Marique P, Peeters F, Herholz, KG, Perani D, Holthoff V, Kalbe E, Anchisi D, Adam S, Collette F, Garraux G. (2005). Cerebral metabolic correlates of four dementia scales in Alzheimer's disease. Journal of Neurology Epub, eScholarID:1d10913
Sobesky J, Thiel A, Ghaemi M, Hilker R, Jacobs A, Rudolf J, Herholz KG, Heiss W D. (2005). Crossed cerebellar diaschisis in acute human stroke: A PET study of serial changes and response to supratentorial reperfusion. Journal of Cerebral Blood Flow and Metabolism Epub, eScholarID:1d10968
Hilker R, Thomas A, Klein J, Weisenbach S, Kalbe E, Burghaus L, Jacobs A, Herholz KG, Heiss W. (2005). Dementia in Parkinson disease: functional imaging of cholinergic and dopaminergic pathways. Neurology, 65( 11), 1716-22. eScholarID:1d14189
Hilker R, Portman A T, Voges J, Staal M J, Burghaus L, van Laar T, Koulousakis A, Maguire R P, Pruim J, Herholz, KG, Sturm V, Heiss W D, Leenders K L. (2005). Disease progression continues in patients with advanced Parkinson's disease and effective subthalamic nucleus stimulation. Journal of Neurology, Neurosurgery and Psychiatry, eScholarID:1d10911
Thiel A, Habedank B, Winhuisen L, Herholz KG, Kessler J, Haupt W F, Heiss W D. (2005). Essential language function of the right hemisphere in brain tumor patients. Annals of Neurology, 57(1), 128-131. eScholarID:1d10908 | DOI:10.1002/ana.20342
Anchisi, D, Borroni, B, Franceschi, M, Kerrouche, N, Kalbe, E, Beuthien-Beumann, B, Cappa, S, Lenz, O, Ludecke, S, Marcone, A, Mielke, R, Ortelli, P, Padovani, A, Pelati, O, Pupi, A, Scarpini, E, Weisenbach, S, Herholz, KG, Salmon, E, Holthoff, V, Sorbi, S, Fazio, F, Perani, D. (2005). Heterogeneity of brain glucose metabolism in mild cognitive impairment and clinical progression to Alzheimer disease. Arch Neurol, 62( 11), 1728-33. eScholarID:1d14184 | DOI:10.1001/archneur.62.11.1728
Jacobs A H, Kracht L W, Grossman A, Roger M A, Thomas A V, Thiel A, Herholz KG. (2005). Imaging in Neurooncology. NeuroRx, 2, 333-347. eScholarID:1d10972 | DOI:10.1602/neurorx.2.2.333
Mosconi L, Pupi A, Herholz KG, Prohovnik I, Nacmias B, De Cristofaro M T R, Fayyaz M, Bracco L, Sorbi S. (2005). Metabolic interaction between ApoE genotype and onset age in Alzheimer's disease: implications for brain reserve. Journal of Neurology, Neurosurgery and Psychiatry, 76 (1), 15-23. eScholarID:1d10910
Thiel A, Haupt W F, Habedank B, Winhuisen L, Herholz KG, Kessler J. (2005). Neuroimaging guided rTMS of left inferior frontal gyrus interferes with repetition priming. Neuroimage, 25 (3), 815-823. eScholarID:1d10909
Hilker F, Schweitzer K, Coburger S, Ghaemi M, Weisenbach S, Jacobs AH, Rudolf J, Herholz KG, Heiss WD. (2005). Nonlinear Progression of Parkinson Disease as Determined by Serial Positron Emission Tomographic Imaging of Striatal Fluorodopa F 18 Activity. Archives of Neurology, 62 (3), 378-382. eScholarID:1d10905
Lange C, Kracht L, Herholz KG, Sachsse U, Irle E. (2005). Reduced glucose metabolism in temporo-parietal cortices of women with borderline personality disorder. Psychiatry Research (Neuroimaging Section) Epub, eScholarID:1d10975
Holthoff VA, Beuthien-Baumann B, Kalbe E, Ludecke S, Lenz O, Zundorf G, Spirling S, Schierz K, Winiecki P, Sorbi S, Herholz, KG. (2005). Regional cerebral metabolism in early Alzheimer's disease with clinically significant apathy or depression. Biol Psychiatry, 57 (4), 412-421. eScholarID:1d10907
Cizek J, Herholz KG, Schrader R. (2005). Robust non-linear registration of 3D medical images with one-to-one deformations. Neuroimage, eScholarID:1d10969
2004
Mosconi L, Sorbi S, Nacmias B, De Cristofaro M T, Fayyaz M, Bracco L, Herholz KG, Pupi A. (2004). Age and ApoE genotype interaction in Alzheimer's disease: an FDG-PET study. Psychiatry Research: Neuroimaging, 130(2), eScholarID:1d10983
Kracht L W, Miletic H, Busch S, Jacobs A H, Voges J, Hoevels M, Lucht H, Herholz KG, Heiss W D. (2004). Brain Tumor Extent with [11C]-L-methionine Positron Emission Tomography: Local Comparison with Stereotactic Histopatholoy. Clinical Cancer Research, 10, 7163-7170. eScholarID:1d10967 | DOI:10.1158/1078-0432.CCR-04-0262
Mosconi L, Nacmias B, Sorbi S, De Cristofaro M T, Fayazz M, Tedde A, Bracco L, Herholz KG, Pupi A. (2004). Brain metabolic decreases related to the dose of the ApoE e4 allele in Alzheimer's disease. Journal of Neurology, Neurosurgery and Psychiatry, 75(3), eScholarID:1d10977
Holthoff V A, Beuthien-Baumann B, Zundorf G, Triemer A, Lundecke S, Winiecki P, Koch R, Fuchtner F, Herholz KG. (2004). Changes in Brain Metabolism Associated with Remission in Unipolar Major Deprssion. Acta Psychiatr.Scand, 110(3), 184-194. eScholarID:1d10980
Kracht L W, Miletic H, Busch S, Jacobs A H, Voges J, Hoevels M, Klein J C, Herholz KG, Heiss W D. (2004). Delineation of brain tumor extent with [11C]L-methionine positron emission tomography: local comparison with stereotactic histopathology. Clinical Cancer Research, 10, 7163-7170. eScholarID:1d26691 | DOI:10.1158/1078-0432.CCR-04-0262
Cizek J, Herholz KG, Vollmar S, Schrader R, Klein J, Heiss W D. (2004). Fast and robust registraion of PET and MR images of human brain. Neuroimage, 22(1), 434-442. eScholarID:1d10979
Mosconi L, Pupi A, De Cristofaro M T, Fayyaz M, Sorbi S, Herholz KG. (2004). Functional interactions of the entorhinal cortex: an 18F-FDG PET study on normal aging and Alzheimer's disease. The journal of Nuclear Medicine, 45(3), 382-392. eScholarID:1d10976
Herholz KG, Weisenbach S, Zundorf G, Lenz O, Schrader H, Bauer B, Kalbe E, Heiss W D. (2004). In-vivo Study of Acetylcholine Esterase in Basal Forebrain, Amygdala, and Cortex in Mild to Moderate Alzheimer disease. Neuroimage, 21(1), 136-143. eScholarID:1d10988 | DOI:10.1016/j.neuroimage.2003.09.042
Mosconi L, Perani D, Sorbi S, Herholz, KG, Nacmias B, Holthoff V, Salmon E, Baron J C, De Cristofaro M T, Padovani A, Borroni B, Franceschi M, Bracco L, Pupi A. (2004). MCI conversion to dementia and the APOE genotype: A prediction study with FDG-PET. Neurology, 63(12), 2332-2340. eScholarID:1d10966
Herholz, KG, Zundorf G, Bauer B, Weisenbach S, Heiss W D, Silman I, Soreq H, Anglister L, Michaelson D M, Fisher A. (2004). Measuring cerebral acetylcholine esterase activity in Alzheimer dementia by PET functional parametric imaging. Cholinergic Mechanisms, eScholarID:1d10981
Heiss WD, Habedank B, Klein J C, Herholz KG, Wienhard K, Lenox M, Nutt R. (2004). Metabolic Rates in Small Brain Nuclei Determined by High-Resolution PET. Journal of Nuclear Medicine, 45(11), 1811-1815. eScholarID:1d10965
Herholz KG, Herscovitch P, Heiss W D. (2004). NeuroPET. Berlin/Heidelberg/NY: Springer. eScholarID:4d134
Galldiks N, Burghaus L, Vollmar S, Cizek J, Impekoven P, Thomas A, Jacobs A H, Herholz KG. (2004). Novel Neuroimaging Findings in a Patient with Cerebral Whipple's Disease: A magnetic Resonance Imaging and Positron Emission Tomography Study. Journal of Neuroimaging, 14(4), 372-376. eScholarID:1d10978
Herholz KG, Heiss W D. (2004). PET in clinical neurology. Molecular Imaging & Biology, 6(4), eScholarID:1d10984
Hilker R, Voges J, Weisenbach S, Kalbe E, Burghaus L, Ghaemi M, Lehrke R, Koulousakis A, Herholz, KG, Sturm V, Heiss W D. (2004). Subthalamic nucleus stimulation restores glucose metabolism in associative and limbic cortices and in cerebellum: evidence from a FDG-PET study in advanced Parkinson's disease. Journal of Cerebral Blood Flow & Metabolism, 24, 7. eScholarID:17d214
Hartmann P, Herholz KG, Salzberger B, Petereit H F. (2004). Unusual and severe symptomatic impairment of neutrophil function after one cycle of temozolomide in patients with malignant glioma. Ann. Hematol, 83(4), eScholarID:1d10982
Vollmar S, Cizek J, Sue M, Klein J, Herholz KG, Jacobs A, Kremer K, Macho V. (2004). VINCI -"Volume imaging in Neurological Research, Co-Registration and ROIs included". Forschung and wissenschaftliches Rechnen 2003. eScholarID:3d839
2003
Thiel A, Hilker R, Kessler J, Habedank B, Herholz KG, Heiss W D. (2003). Activation of basal ganglia loops in idiopathic Parkinson's disease: a PET study. J. Neural Transm, 110(11), eScholarID:1d10989
Zundorf G, Kerrouche N, Herholz KG, Baron J C. (2003). An efficient principal component analysis for multivariate 3D voxel-based mapping of brain functional imaging data sets as applied to FDG-PET and normal aging. Hum.Brain Mapp, 18(1), eScholarID:1d11003
Mosconi L, Sorbi S, Nacmias B, De Cristofaro M RT R, Fayyaz M, Cellini E, Bagnoli S, Bracco L, Herholz, KG, Pupi A. (2003). Brain metabolic differences between sporadic and familial Alzheimer's disease. Neurology, 61(8), eScholarID:1d10991
Scheidhauer K, Herholz KG, Ebmeier K P. (2003). Comparing HMPAO-SPECT and FDG-PET in Alzheimer's Disease. SPECT in dementia. Basel. eScholarID:3d466
Hilker R, Voges J, Ghaemia M, Lehrke R, Rudolf J, Koulousakis A, Herholz, KG, Wienhard K, Sturm V, Heiss W D. (2003). Deep brain stimulation of the subthalamic nucleus does not increase the striatal dopamine concentration in parkinsonian humans. Mov Disord, 18(1), eScholarID:1d11001
Heiss W D, Thiel A, Kessler J, Herholz KG. (2003). Disturbance and recovery of language function: correlates in PET activation studies. Neuroimage, 20(1), eScholarID:1d10990
Heiss W D, Thiel A, Winhuisen L, Muhlberger B, Kessler J, Herholz KG. (2003). Functional imaging in the assessment of capability for recovery after stroke. Journal of Rehabilitation Medicine, 35(Suppl), 27-33. eScholarID:1d10997
Jacobs A H, Voges J, Kracht L W, Dittmar C, Winkeler A, Thomas A, Wienhard K, Herholz KG, Heiss W D. (2003). Imaging in gene therapy of patients with glioma. J. Neurooncol, 65(3), eScholarID:1d10985
Fesl G, Moriggl B, Schmid U D, Naidich T P, Herholz KG, Yousry T A. (2003). Inferior central sulcus: variations of anatomy and function on the example of the motor tongue area. Neuroimage, 20(1), eScholarID:1d10992
Kracht L W, Friese M, Herholz KG, Schroeder R, Bauer B, Jacobs A, Heiss W D. (2003). Methyl-[(11)C]- l-methionine uptake as measured by positron emission tomography correlates in microvessel density in patients with glioma. Eur.J Nucl Med Mol.Imaging, 30(6), eScholarID:1d11000
Herholz KG, Kracht L, Heiss W D. (2003). Monitoring of the Effect of Chemotherapy in a Mixed Glioma by C-11-methionine PET. Journal of Neuroimaging, 13(3), eScholarID:1d11002
Herholz KG. (2003). PET studies in dementia. Annals of Nuclear Medicine, 17(2), 79-89. eScholarID:1d10999
Jacobs A H, Li H, Winkeler A, Hilker R, Knoess C, Ruger A, Galldiks N, Schaller B, Sobesky J, Kracht L, Monfared P, Klein M, Vollmar S, Bauer B, Wagner R, Graf R, Wienhard K, Herholz, KG, Heiss W D. (2003). PET-based molecular imaging in neuroscience. Eur J Nucl Med Mol.Imaging, 30, eScholarID:1d10998
Salmon E, Garraux G, Delbeuck X, Collette F, Kalbe E, Zuendorf G, Perani D, Fazio F, Herholz KG. (2003). Predominant ventromedial frontopolar metabolic impairment in frontoemporal dementia. Neuroimage, 20(1), eScholarID:1d10993
Sturm V, Lenartz D, Koulousakis A, Treuer H, Herholz KG, Klein J C, Klosterkitter J. (2003). The Nucleus Accumbens: A Target for Deep Brain Stimulation in Obsessive-Compulsive-and Anxiety-Disorders. Journal of Chemical Neuroanatomy, 26(4), eScholarID:1d10996
Ebmeier K P, Darcourt J, Dougall N J, Glasbus M F, Herholz, KG, Koulibaly P M, Migneco O, Nobili F, Pupi A, Robert P, Rodriguez G, Scheidhauer K, Ebmeier K P. (2003). Voxel-based approaches in clinical imaging. SPECT in dementia. Basel. eScholarID:3d840
2002
Herholz KG, Kessler J, Ehlen P, Kalbe E, Strotmann T, Markowitsch H J, Senda M, Kimura Y, Herscovitch P. (2002). Brain regions involved in learning face-name associations and the effects of age, performance, and learning phase. Brain imaging using SPECT. San Diego, CA: Academic Press. eScholarID:3d467
Hilker R, Voges J, Thiel A, Ghaemi M, Herholz KG, Sturm V, Heiss W D. (2002). Deep brain stimulation of the subthalamic nucleus versus levodopa challenge in Parkinson's disease: measuring the on-and off-conditions with FDG-PET. Journal of Neural transmission, 10, eScholarID:1d11021
Huber M, Herholz KG, Habedank B, Thiel A, Muller-Kuppers M, Ebel H, Subic-Wrana C, Kohle K, Heiss W D. (2002). Differente Muster regionaler Hirnaktivitat nach emotionaler Stimulation bei alexithymen Patienten im Vergleich zu Normalpersonen. Eine Positronen-Emissions-Tomographische (PET) Studie mit 150-H2O und emotionaler Stimulierung durch autobiographische Erinnerung. Psychother. Psychosom. Med Psychol, 51(11), eScholarID:1d11020
Herholz KG, Schopphoff H, Schmidt M, Mielke R, Eschner W, Scheidhauer K, Schicha H, Heiss W D, Ebmeier K P. (2002). Direct comparison of spatially normalized PET and SPECT scans in Alzheimer disease. Journal of Nuclear Medicine, 43(1), eScholarID:1d11024
Herholz, KG, Salmon E, Perani D, Baron J C, Holthoff V, Frolich L, Ito K, Mielke R, Kalbe E, Zundorf G, Delbeuck X, Pelati O, Anchisi D, Fazio F, Kerrouche N, Calautti C, Beuthien-Baumann B, Menzel C, Schroder J, Kato T, Arahata Y, Henze M, Heiss W D. (2002). Discrimination between Alzheimer Dementia and Controls by Automated Analysis of Multicenter FDG PET. Neuroimage, 17, 302-316. eScholarID:1d11023 | DOI:10.1006/nimg.2002.1208
Szelies B, Sobesky J, Pawlik G, Mielke R, Bauer B, Herholz KG, Heiss W D. (2002). Impaired benzodiazepine receptor binding in peri-lesional cortex of patients with symptomatic epilepsies studied by [11C]-flumazenil PET. Eur.J Neurol, 9(2), eScholarID:1d11022
Jacobs A , Winkler A, Dittmar C, Gossman A, Deckert M, Kracht L, Thiel A, Garlip G, Hilker R, Sobesky J, Vollmar S, Kummer C, Graf R, Voges J, Wienhard K, Herholz, KG, Heiss W D. (2002). Molecular and functional imaging technology for the development of efficient treatment strategies for gliomas. Technol. Cancer Res Treat, 1(3), eScholarID:1d11008
Zundorf G, Herholz, KG, Lercher M, Wienhard K, Bauer B, Weisenbach S, Heiss W D, Senda M, Kimura Y, Herscovitch P. (2002). PET functional parametric images of acetylcholine esterase activity without blood sampling. Brain imaging using PET. San Diego, CA: Academic Press. eScholarID:3d611
Heiss W D, Thiel A, Kessler J, Herholz KG. (2002). Sprachaktivierung im PET bei isch,mischen Insulten und Hirntumoren. Zentralblatt fur Neurochirurgie, 63(4), eScholarID:1d32753
Hilker R, Klein C, Hedrich K, Ozelius L J, Vieregge P, Herholz KG, Pramstaller P P, Heiss W D. (2002). The striatal dopaminergic deficit is dependent on the number of mutant alleles in a family with mutations in the parkin gene: evidence for enzymatic parkin function in humans. Neurosi.Lett, 323(1), eScholarID:1d32785
2001
Herholz KG, Perani D, Fazekas F, Markus H, Baumgartner R W, Baron J C. (2001). A survey of neuroimaging research in European neurological departments. Eur.J Neurol, 8(2), eScholarID:1d11025
Huber M, Siol T, Herholz KG, Lenz O, Kohle K, Heiss W D. (2001). Activation of Thalamo-Cortical Systems in Post-Traumatic Flashbacks: A Positron Emission Tomography Study. Traumatology, 7(4), eScholarID:1d11026
Jauss M, Herholz KG, Kracht L, Pantel J, Hartmann T, Jensen M, Essig M, Schroder. (2001). Frontotemporal dementia: Clinical, neuroimaging and molecular biological findings in 6 patients. European Archives of Psychiatry & Clinical Neuroscience, 251, eScholarID:1d11027
Ghaemi M, Rudolf J, Hilker R, Herholz KG. (2001). Increased pineal Fdopa uptake is related to severity of Parkinson's disease - a PET study. J. Pineal Res, 30 (4), eScholarID:1d11095
Herholz KG, Ehlen P, Kessler J, Strotmann T, Kalbe E, Markowitsch H J. (2001). Learning face-name associations and the effect of age and performance:a PET activation study. Neuropsychologia, 39, eScholarID:1d11098
Herholz KG, Lercher M, Wienhard K, Bauer B, Lenz O, Heiss W D. (2001). PET measurement of cerebral acetylcholine esterase activity without blood sampling. European Journal of Nuclear Medicine, 28, eScholarID:1d11097
Thiel A, Herholz KG, Koyuncu A, Ghaemi M, Kracht L W, Habedank B, Heiss W D. (2001). Plasticity of language networks in patients with brain tumors. A positron emission tomography activation study. Annals of Neurology, 50, eScholarID:1d11028
Hilker R, Klein C, Ghaemi M, Kis B, Strotmann T, Ozelius L J, Lenz O, Vieregge P, Herholz, KG, Heiss W D, Pramstaller P P. (2001). Positron emission tomographic analysis of the nigrostriatal dopaminergic system in familial parkinsonism associated with mutations in the parkin gene. Annals of Neurology, 49, 367-76. eScholarID:1d11096 | DOI:10.1002/ana.74
2000
Bartenstein, P, Grünwald, F, Kuwert, T, Tatsch, K, Sabri, O, Benkert, O, Fahlbusch, R, Gründer, G, Herholz, KG, Weiller, C. (2000). Clinical applications of single photon emission tomography in neurology. 2. Dementia, psychoses, inflammation, skull and brain injuries. Nuklearmedizin, 39( 8), 218-32. eScholarID:1d14182
Bartenstein P, Grunwald F, Kuwert T, Tatsch K, Sabri O, Benkert O, Fahlbusch R, Grunder G, Herholz, KG, Weiller C. (2000). Clinical applications of single photon emission tomography in neuromedicine. 1. Neuro-oncology, epilepsy, movement disorders, cerebrovascular disease. Nuklearmedizin, 39(7), 180-95. eScholarID:1d14183
Thiel A, Pietrzyk U, Sturm V, Herholz KG, Hovels M, Schroder R. (2000). Enhanced accuracy in differential diagnosis of radiation necrosis by positron emission tomography-magnetic resonance imaging coregistration: technical case report. Neurosurgery, 46 (1), eScholarID:1d11099
Kessler J, Mielke R, Grond M, Herholz KG, Heiss W D. (2000). Frontal lobe tasks do not reflect frontal lobe function in patients with probable Alzheimer's disease. Journal of Neuroscience, 1, eScholarID:1d11101
Herholz KG, Heiss W D. (2000). Functional imaging correlates of recovery after stroke in humans. Journal of Cerebral Blood Flow & Metabolism, 20, eScholarID:1d11100
Herholz KG, Bauer B, Wienhard K, Kracht L, Mielke R, Lenz O, Strotmann T, Heiss W D. (2000). In-vivo measurements of regional acetylcholine esterase activity in degenerative dementia: comparison with blood flow and glucose metabolism. J Neural Transm, 12, eScholarID:1d11174
Muzik O, Da Silva E A, Juhasz C, Chugani D C, Shah J, Nagy F, Canady A, von Stockhausen H M, Herholz, KG, Gates J, Frost M, Ritter F, Watson C, Chugani H T. (2000). Intracranial EEG vs. flumazenil and glucose PET in children with extratemporal lobe epilepsy. Neurology, 54, eScholarID:1d11175
