Boutin, H., Prenant, C., Maroy, R., Galea, J., Greenhalgh, A., Smigova, A., Cawthorne, C., Julyan, P., Wilkinson, S., Banister, S., Brown, G., Herholz, K., Kassiou, M. & Rothwell, N (2013). [(18)F]DPA-714: Direct Comparison with [(11)C]PK11195 in a Model of Cerebral Ischemia in Rats. PLoS One, 8(2), e56441. eScholarID:189648 | PMID:23418569 | DOI:10.1371/journal.pone.0056441
Denes, A., Wilkinson, F., Bigger, B., Chu, M., Rothwell, N. & Allan, S (2013). Central and haematopoietic interleukin-1 both contribute to ischaemic brain injury in mice. Dis Model Mech, eScholarID:194747 | PMID:23519030 | DOI:10.1242/dmm.011601
Girard, S., Brough, D., Lopez-Castejon, G., Giles, J., Rothwell, N. & Allan, S (2013). Microglia and macrophages differentially modulate cell death after brain injury caused by oxygen-glucose deprivation in organotypic brain slices. Glia, eScholarID:189647 | PMID:23404620 | DOI:10.1002/glia.22478
2012
Allen, C., Thornton, P., Denes, A., McColl, B., Pierozynski, A., Monestier, M., Pinteaux, E., Rothwell, N. & Allan, S (2012). Neutrophil Cerebrovascular Transmigration Triggers Rapid Neurotoxicity through Release of Proteases Associated with Decondensed DNA. J Immunol, 189(1), 381-92. eScholarID:165343 | PMID:22661091 | DOI:10.4049/jimmunol.1200409
Cantrill, C., Skinner, R., Rothwell, N. & Penny, J (2012). An immortalised astrocyte cell line maintains the in vivo phenotype of a primary porcine in vitro blood-brain barrier model. Brain Res, eScholarID:169096 | PMID:22940232 | DOI:10.1016/j.brainres.2012.08.031
Denes, A., Drake, C., Stordy, J., Chamberlain, J., McColl, B., Gram, H., Crossman, D., Francis, S., Allan, S. & Rothwell, N (2012). Interleukin-1 mediates neuroinflammatory changes associated with diet-induced atherosclerosis. J Am Heart Assoc, 1(3), e002006. eScholarID:182945 | PMID:23130147 | DOI:10.1161/JAHA.112.002006
Greenhalgh, A., Brough, D., Robinson, E., Girard, S., Rothwell, N. & Allan, S (2012). Interleukin-1 receptor antagonist is beneficial after subarachnoid haemorrhage in rat by blocking haem-driven inflammatory pathology. Dis Model Mech, eScholarID:165342 | PMID:22679224 | DOI:10.1242/dmm.008557
Hopkins, S., McMahon, C., Singh, N., Galea, J., Hoadley, M., Scarth, S., Patel, H., Vail, A., Hulme, S., Rothwell, N., King, A. & Tyrrell, P (2012). Cerebrospinal fluid and plasma cytokines after subarachnoid haemorrhage: CSF interleukin-6 may be an early marker of infection. J Neuroinflammation, 9(1), 255. eScholarID:182946 | PMID:23176037 | DOI:10.1186/1742-2094-9-255
Leow-Dyke, S., Allen, C., Denes, A., Nilsson, O., Maysami, S., Bowie, A., Rothwell, N. & Pinteaux, E (2012). Neuronal toll-like receptor 4 signaling induces brain endothelial activation and neutrophil transmigration in vitro. J Neuroinflammation, 9, 230. eScholarID:184725 | PMID:23034047 | DOI:10.1186/1742-2094-9-230
McMahon, C., Hopkins, S., Vail, A., King, A., Smith, D., Illingworth, K., Clark, S., Rothwell, N. & Tyrrell, P (2012). Inflammation as a predictor for delayed cerebral ischemia after aneurysmal subarachnoid haemorrhage. J Neurointerv Surg, eScholarID:169100 | PMID:22952245 | DOI:10.1136/neurintsurg-2012-010386
Pradillo, J., Denes, A., Greenhalgh, A., Boutin, H., Drake, C., McColl, B., Barton, E., Proctor, S., Russell, J., Rothwell, N. & Allan, S (2012). Delayed administration of interleukin-1 receptor antagonist reduces ischemic brain damage and inflammation in comorbid rats. J Cereb Blood Flow Metab, eScholarID:165344 | PMID:22781338 | DOI:10.1038/jcbfm.2012.101
Smith, C., Emsley, H., Udeh, C., Vail, A., Hoadley, M., Rothwell, N., Tyrrell, P. & Hopkins, S (2012). Interleukin-1 receptor antagonist reverses stroke-associated peripheral immune suppression. Cytokine, 58(3), 384-9. eScholarID:165345 | PMID:22445501 | DOI:10.1016/j.cyto.2012.02.016
2011
Cawthorne, C., Prenant, C., Smigova, A., Julyan, P., Maroy, R., Herholz, K., Rothwell, N. & Boutin, H (2011). Biodistribution, pharmacokinetics and metabolism of interleukin-1 receptor antagonist (IL-1RA) using [¹⁸F]-IL1RA and PET imaging in rats. Br J Pharmacol, 162(3), 659-72. eScholarID:126179 | PMID:20942812 | DOI:10.1111/j.1476-5381.2010.01068.x
Cawthorne, C., Prenant, C., Smigova, A., Julyan, P., Maroy, R., Herholz, K., Rothwell, N. & Boutin, H (2011). Biodistribution, pharmacokinetics and metabolism of interleukin-1 receptor antagonist (IL-1RA) using [¹⁸F]-IL1RA and PET imaging in rats. Br J Pharmacol, 162(3), 659-72. eScholarID:169102 | PMID:20942812 | DOI:10.1111/j.1476-5381.2010.01068.x
Denes, A., McColl, B., Leow-Dyke, S., Chapman, K., Humphreys, N., Grencis, R., Allan, S. & Rothwell, N (2011). Experimental stroke-induced changes in the bone marrow reveal complex regulation of leukocyte responses. J Cereb Blood Flow Metab, 31(4), 1036-50. eScholarID:126181 | PMID:21045863 | DOI:10.1038/jcbfm.2010.198
Denes, A., Pinteaux, E., Rothwell, N. & Allan, S (2011). Interleukin-1 and stroke: biomarker, harbinger of damage, and therapeutic target. Cerebrovasc Dis, 32(6), 517-27. eScholarID:159455 | PMID:22104408 | DOI:10.1159/000332205
Drake, C., Boutin, H., Jones, M., Denes, A., McColl, B., Selvarajah, J., Hulme, S., Georgiou, R., Hinz, R., Gerhard, A., Vail, A., Prenant, C., Julyan, P., Maroy, R., Brown, G., Smigova, A., Herholz, K., Kassiou, M., Crossman, D., Francis, S., Proctor, S., Russell, J., Hopkins, S., Tyrrell, P., Rothwell, N. & Allan, S (2011). Brain inflammation is induced by co-morbidities and risk factors for stroke. Brain Behav Immun, eScholarID:126182 | PMID:21356305 | DOI:10.1016/j.bbi.2011.02.008
Drake, C., Boutin, H., Jones, M., Denes, A., McColl, B., Selvarajah, J., Hulme, S., Georgiou, R., Hinz, R., Gerhard, A., Vail, A., Prenant, C., Julyan, P., Maroy, R., Brown, G., Smigova, A., Herholz, K., Kassiou, M., Crossman, D., Francis, S., Proctor, S., Russell, J., Hopkins, S., Tyrrell, P., Rothwell, N. & Allan, S (2011). Brain inflammation is induced by co-morbidities and risk factors for stroke. Brain Behav Immun, 25(6), 1113-22. eScholarID:169101 | PMID:21356305 | DOI:10.1016/j.bbi.2011.02.008
Galea, J., Ogungbenro, K., Hulme, S., Greenhalgh, A., Aarons, L., Scarth, S., Hutchinson, P., Grainger, S., King, A., Hopkins, S., Rothwell, N. & Tyrrell, P (2011). Intravenous anakinra can achieve experimentally effective concentrations in the central nervous system within a therapeutic time window: results of a dose-ranging study. J Cereb Blood Flow Metab, 31(2), 439-47. eScholarID:126180 | PMID:20628399 | DOI:10.1038/jcbfm.2010.103
Greenhalgh, A., Ogungbenro, K., Rothwell, N. & Galea, J (2011). Translational pharmacokinetics: challenges of an emerging approach to drug development in stroke. Expert Opin Drug Metab Toxicol, 7(6), 681-95. eScholarID:126183 | PMID:21521135 | DOI:10.1517/17425255.2011.570259
Nguyen, L., Rothwell, N., Pinteaux, E. & Boutin, H (2011). Contribution of interleukin-1 receptor accessory protein B to interleukin-1 actions in neuronal cells. Neurosignals, 19(4), 222-30. eScholarID:159452 | PMID:21968452 | DOI:10.1159/000330803
Selvarajah, J., Smith, C., Hulme, S., Georgiou, R., Sherrington, C., Staniland, J., Illingworth, K., Jury, F., Payton, A., Ollier, W., Vail, A., Rothwell, N., Hopkins, S. & Tyrrell, P (2011). Does inflammation predispose to recurrent vascular events after recent transient ischaemic attack and minor stroke? The North West of England transient ischaemic attack and minor stroke (NORTHSTAR) study. Int J Stroke, 6(3), 187-94. eScholarID:126184 | PMID:21557802 | DOI:10.1111/j.1747-4949.2010.00561.x
Small, B., McColl, B., Allmendinger, R., Pahle, J., López-Castejón, G., Rothwell, N., Knowles, J., Mendes, P., Brough, D. & Kell, D (2011). Efficient discovery of anti-inflammatory small-molecule combinations using evolutionary computing. Nat Chem Biol, 7(12), 902-8. eScholarID:159453 | PMID:22020553 | DOI:10.1038/nchembio.689
2010
Dénes A, Humphreys N, Lane TE, Grencis R, Rothwell N. (2010). Chronic systemic infection exacerbates ischemic brain damage via a CCL5 (regulated on activation, normal T-cell expressed and secreted)-mediated proinflammatory response in mice. J Neurosci, 30(30), eScholarID:97971 | DOI:10.1523/JNEUROSCI.1227-10.2010
Thornton P, McColl BW, Cooper L, Rothwell NJ, Allan SM. (2010). Interleukin-1 Drives Cerebrovascular Inflammation via MAP Kinase-Independent Pathways. Curr Neurovasc Res, 7(4), 330-340. eScholarID:97965 | DOI:10.2174/156720210793180800
Denes, A., Thornton, P., Rothwell, N. & Allan, S (2010). Inflammation and brain injury: acute cerebral ischaemia, peripheral and central inflammation. Brain Behav Immun, 24(5), 708-23. eScholarID:126185 | PMID:19770034 | DOI:10.1016/j.bbi.2009.09.010
Greenhalgh, A., Galea, J., Dénes, A., Tyrrell, P. & Rothwell, N (2010). Rapid brain penetration of interleukin-1 receptor antagonist in rat cerebral ischaemia: pharmacokinetics, distribution, protection. Br J Pharmacol, 160(1), 153-9. eScholarID:97975 | PMID:20412072 | DOI:10.1111/j.1476-5381.2010.00684.x
McColl, B., Rose, N., Robson, F., Rothwell, N. & Lawrence, C (2010). Increased brain microvascular MMP-9 and incidence of haemorrhagic transformation in obese mice after experimental stroke. J Cereb Blood Flow Metab, 30(2), 267-72. eScholarID:76669 | PMID:19826431 | DOI:10.1038/jcbfm.2009.217
Prenant, C., Cawthorne, C., Fairclough, M., Rothwell, N. & Boutin, H (2010). Radiolabeling with fluorine-18 of a protein, interleukin-1 receptor antagonist. Appl Radiat Isot, 68(9), 1721-7. eScholarID:97976 | PMID:20435481 | DOI:10.1016/j.apradiso.2010.04.007
Thornton, P., McColl, B., Greenhalgh, A., Denes, A., Allan, S. & Rothwell, N (2010). Platelet interleukin-1{alpha} drives cerebrovascular inflammation. Blood, eScholarID:78635 | PMID:20200351 | DOI:10.1182/blood-2009-11-252643
2009
Brough D, Pelegrin P, Rothwell NJ. (2009). Pannexin-1-dependent caspase-1 activation and secretion of IL-1beta is regulated by zinc. European journal of immunology, 39(2), 352-8. eScholarID:1c8177 | PMID:19130485 | DOI:10.1002/eji.200838843
Luheshi NM, Rothwell NJ, Brough D. (2009). The dynamics and mechanisms of interleukin-1alpha and Beta nuclear import. Traffic (Copenhagen, Denmark), 10(1), 16-25. eScholarID:1c8176 | PMID:18939951 | DOI:10.1111/j.1600-0854.2008.00840.x
Chapman, K., Dale, V., Dénes, A., Bennett, G., Rothwell, N., Allan, S. & McColl, B (2009). A rapid and transient peripheral inflammatory response precedes brain inflammation after experimental stroke. J Cereb Blood Flow Metab, 29(11), 1764-8. eScholarID:76672 | PMID:19654587 | DOI:10.1038/jcbfm.2009.113
Denes, A., Thornton, P., Rothwell, N. & Allan, S (2009). Inflammation and brain injury: Acute cerebral ischaemia, peripheral and central inflammation. Brain Behav Immun, eScholarID:76670 | PMID:19770034 | DOI:10.1016/j.bbi.2009.09.010
Luheshi, N., Rothwell, N. & Brough, D (2009). Dual functionality of interleukin-1 family cytokines: implications for anti-interleukin-1 therapy. Br J Pharmacol, 157(8), 1318-29. eScholarID:76671 | PMID:19681864 | DOI:10.1111/j.1476-5381.2009.00331.x
Skinner, R., Gibson, R., Rothwell, N., Pinteaux, E. & Penny, J (2009). Transport of interleukin-1 across cerebromicrovascular endothelial cells. Br J Pharmacol, 156(7), 1115-23. eScholarID:76673 | PMID:19298391 | DOI:10.1111/j.1476-5381.2008.00129.x
2008
Parry-Jones AR, Liimatainen T, Kauppinen RA, Gröhn OH, Rothwell NJ. (2008). Interleukin-1 exacerbates focal cerebral ischemia and reduces ischemic brain temperature in the rat. Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine, 59(6), 1239-49. eScholarID:1c8173 | PMID:18421691 | DOI:10.1002/mrm.21531
Clark S, McMahon C, Gueorguieva I, Rowland M, Scarth S, Georgiou R, Tyrrell PJ, Hopkins SJ, Rothwell NJ. (2008). Interleukin-1 receptor antagonist penetrates human brain at experimentally therapeutic concentrations. J Cereb Blood Flow Metab, 28( 2), eScholarID:1d16878
Tsakiri N, Kimber I, Rothwell NJ, Pinteaux E. (2008). Interleukin-1-induced interleukin-6 synthesis is mediated by the neutral sphingomyelinase/Src kinase pathway in neurones. British Journal of Pharmacology, 153, 775-783. eScholarID:1c7099 | PMID:18059318 | DOI:10.1038/sj.bjp.0707610
Thornton P, Pinteaux E, Allan SM, Rothwell NJ. (2008). Matrix metalloproteinase-9 and urokinase plasminogen activator mediate interleukin-1-induced neurotoxicity. Molecular Cellular Neuroscience, 37, 135-142. eScholarID:1c7077 | PMID:17939964 | DOI:10.1016/j.mcn.2007.09.002
Tsakiri N, Kimber I, Rothwell NJ, Pinteaux E. (2008). Mechanisms of interleukin-6 synthesis and release induced by interleukin-1 and cell depolarisation in neurones. Molecular Cellular Neuroscience, 37, 110-118. eScholarID:1c7096 | PMID:17933551 | DOI:10.1016/j.mcn.2007.09.001
Wang P, Rothwell NJ, Pinteaux E, Brough D. (2008). Neuronal injury induces the release of pro-interleukin-1beta from activated microglia in vitro. Brain research, 1236, 1-7. eScholarID:1c8174 | PMID:18722361 | DOI:10.1016/j.brainres.2008.08.001
Gueorguieva I, Clark SR, McMahon CJ, Scarth S, Rothwell NJ, Tyrrell PJ, Hopkins SJ, Rowland M. (2008). Pharmacokinetic modelling of interleukin-1 receptor antagonist in plasma and cerebrospinal fluid of patients following subarachnoid haemorrhage. Br J Clin Pharmacol, 65(3), eScholarID:1d16890
Selvarajah JR, Scott M, Stivaros S, Hulme S, Georgiou R, Rothwell NJ, Tyrrell PJ, Jackson A-. (2008). Potential surrogate markers of cerebral microvascular angiopathy in asymptomatic subjects at risk of stroke. European Society of Radiology, eScholarID:1d18692 | DOI:10.1007/s00330-008-1202-8
McColl BW, Rothwell NJ, Allan SM. (2008). Systemic inflammation alters the kinetics of cerebrovascular tight junction disruption after experimental stroke in mice. The Journal of neuroscience : the official journal of the Society for Neuroscience, 28(38), 9451-62. eScholarID:1c8178 | PMID:18799677 | DOI:10.1523/JNEUROSCI.2674-08.2008
2007
Ross J, Brough D, Gibson RM, Loddick SA, Rothwell NJ. (2007). A selective, non-peptide caspase-1 inhibitor, VRT-018858, markedly reduces brain damage induced by transient ischemia in the rat. Neuropharmacology, 53(5), 638-42. eScholarID:1c7094 | PMID:17845807 | DOI:10.1016/j.neuropharm.2007.07.015
Brough D, Rothwell NJ. (2007). Caspase-1-dependent processing of pro-interleukin-1beta is cytosolic and precedes cell death. The Journal of Cell Science, 120, 772-781. eScholarID:1c6261 | DOI:10.1242/jcs.03377
Emsley HC, Smith CJ, Gavin CM, Georgiou RF, Vail A, Barberan EM, Illingworth K, Scarth S, Wickramasinghe V, Hoadley ME, Rothwell NJ, Tyrrell PJ, Hopkins SJ. (2007). Clinical outcome following acute ischaemic stroke relates to both activation and autoregulatory inhibition of cytokine production. BMC neurology, 7, 5. eScholarID:1c6526 | PMID:17328808 | DOI:10.1186/1471-2377-7-5
Emsley, HCA, Smith, CJ, Gavin, CCM, Georgiou, R, Vail, A, Barberan, EM, Illingworth, K, Scarth, S, Wickramasinghe, V, Hoadley, M, Rothwell, NJ, Tyrrell, PJ, Hopkins, SJ. (2007). Clinical outcome following acute ischaemic stroke relates to both activation and autoregulatory inhibition of cytokine production. BMC Neurol, 7, eScholarID:1d16882 | DOI:10.1186/1471-2377-7-5
Hutchinson PJ, O'Connell MT, Rothwell NJ, Hopkins SJ, Nortje J, Carpenter KL, Timofeev I, Al-Rawi PG, Menon DK, Pickard JD. (2007). Inflammation in human brain injury: intracerebral concentrations of IL-1alpha, IL-1beta, and their endogenous inhibitor IL-1ra. Journal of neurotrauma, 24(10), 1545-57. eScholarID:1c7098 | PMID:17970618 | DOI:10.1089/neu.2007.0295
Hutchinson, P, O'Connell, M, Rothwell, NJ, Hopkins, SJ, Nortje, J, Carpenter, K, Timofeev, I, Al-Rawi, P, Menon, D, Pickard, J. (2007). Inflammation in human brain injury: intracerebral concentrations of IL-1alpha, IL-1beta, and their endogenous inhibitor IL-1ra. J Neurotrauma, 24( 10), eScholarID:1d16888
Watson PM, Humphries MJ, Relton J, Rothwell NJ, Verkhratsky A, Gibson RM. (2007). Integrin-binding RGD peptides induce rapid intracellular calcium increases and MAPK signaling in cortical neurons. Molecular and cellular neurosciences, 34(2), 147-54. eScholarID:1c6527 | PMID:17150373 | DOI:10.1016/j.mcn.2006.10.007
Simi A, Tsakiri N, Wang P, Rothwell NJ. (2007). Interleukin-1 and inflammatory neurodegeneration. Biochemical Society transactions, 35(Pt 5), 1122-6. eScholarID:1c7097 | PMID:17956293 | DOI:10.1042/BST0351122
Clark SR, McMahon CJ, Gueorguieva I, Rowland M, Scarth S, Georgiou R, Tyrrell PJ, Hopkins SJ, Rothwell NJ. (2007). Interleukin-1 receptor antagonist penetrates human brain at experimentally therapeutic concentrations. eScholarID:1c7093 | PMID:17684519 | DOI:10.1038/sj.jcbfm.9600537
Pinteaux E, Inoue W, Schmidt L, Molina-Holgado F, Rothwell NJ, Luheshi GN. (2007). Leptin induces interleukin-1beta release from rat microglial cells through a caspase 1 independent mechanism. Journal of Neurochemistry, 102, 826-833. eScholarID:1c6513 | PMID:17419800 | DOI:10.1111/j.1471-4159.2007.04559.x
Miggin SM, Pålsson-McDermott E, Dunne A, Jefferies C, Pinteaux E, Banahan K, Murphy C, Moynagh P, Yamamoto M, Akira S, Rothwell N, Golenbock D, Fitzgerald KA, O'Neill LA. (2007). NF-kappaB activation by the Toll-IL-1 receptor domain protein MyD88 adapter-like is regulated by caspase-1. Proceedings of the National Academy of Sciences of the United States of America, 104(9), 3372-7. eScholarID:1c6514 | PMID:17360653 | DOI:10.1073/pnas.0608100104
Gueorguieva I, Clark SR, McMahon CJ, Scarth S, Rothwell NJ, Tyrell PJ, Hopkins SJ, Rowland M. (2007). Pharmacokinetic modelling of interleukin-1 receptor antagonist in plasma and cerebrospinal fluid of patients following subarachnoid haemorrhage. eScholarID:1c7095 | PMID:17875190 | DOI:10.1111/j.1365-2125.2007.03026.x
McColl BW, Allan SM, Rothwell NJ. (2007). Systemic inflammation and stroke: aetiology, pathology and targets for therapy. Biochemical Society transactions, 35(Pt 5), 1163-5. eScholarID:1c7078 | PMID:17956302 | DOI:10.1042/BST0351163
McColl BW, Rothwell NJ, Allan SM. (2007). Systemic inflammatory stimulus potentiates the acute phase and CXC chemokine responses to experimental stroke and exacerbates brain damage via interleukin-1- and neutrophil-dependent mechanisms. The Journal of neuroscience : the official journal of the Society for Neuroscience, 27(16), 4403-12. eScholarID:1c6537 | PMID:17442825 | DOI:10.1523/JNEUROSCI.5376-06.2007
2006
Andre R, Moggs JG, Kimber I, Rothwell NJ, Pinteaux E. (2006). Gene regulation by IL-1beta independent of IL-1R1 in the mouse brain. Glia, 53(5), 477-83. eScholarID:1c5628 | PMID:16358337 | DOI:10.1002/glia.20302
Thornton P, Pinteaux E, Gibson RM, Allan SM, Rothwell NJ. (2006). Interleukin-1-induced neurotoxicity is mediated by glia and requires caspase activation and free radical release. Journal of Neurochemistry, 98, 258-66. eScholarID:1c5617 | PMID:16805812 | DOI:10.1111/j.1471-4159.2006.03872.x
Patel HC, Ross FM, Heenan LE, Davies RE, Rothwell NJ, Allan SM. (2006). Neurodegenerative actions of interleukin-1 in the rat brain are mediated through increases in seizure activity. Journal of neuroscience research, 83(3), 385-91. eScholarID:1c5620 | PMID:16358339 | DOI:10.1002/jnr.20735
Pinteaux E, Rothwell NJ, Boutin H. (2006). Neuroprotective actions of endogenous interleukin-1 receptor antagonist (IL-1ra) are mediated by glia. Glia, 53(5), 551-6. eScholarID:1c5627 | PMID:16374779 | DOI:10.1002/glia.20308
Pinteaux E, Rothwell NJ, Boutin H. (2006). Neuroprotective actions of endogenous interleukin-1 receptor antagonist(IL-1ra) are mediated by glia. Glia, 53 (5), eScholarID:1d33139
Lucas SM, Rothwell NJ, Gibson RM. (2006). The role of inflammation in CNS injury and disease. British journal of pharmacology, 147 Suppl 1, S232-40. eScholarID:1c5626 | PMID:16402109 | DOI:10.1038/sj.bjp.0706400
Smith CJ, Emsley HCA, Vail A, Georgiou R, Rothwell NJ, Tyrrell PJ, Hopkins SJ. (2006). Variability of the systemic acute phase response after ischemic stroke. J Neuro Sci, 251(1-2), eScholarID:1d27470 | DOI:10.1016/j.jns.2006.09.011
2005
Emsley C A, Smith CJ, Georgiou R, Vail A, Hopkins SJ, Rothwell NJ, Tyrrell PJ. (2005). A randomised phase II study of interleukin-1 receptor antagonist in acute stroke patients. Journal of Neurol. Neurosurg. Psychiatry, 76, eScholarID:1d11508 | DOI:10.1136/jnnp.2004.054882
Bano D, Young KW, Guerin CJ, LeFeuvre R, Rothwell NJ, Naldini L, Rizzuto R, Carafoli E, Nicotera P. (2005). Cleavage of the plasma membrane Na+/Ca2+ exchanger in excitotoxicity. Cell, 120(2), 275-85. eScholarID:1c4614 | PMID:15680332 | DOI:10.1016/j.cell.2004.11.049
Emsley HC, Smith CJ, Georgiou RF, Vail A, Tyrrell PJ, Barberan EM, Rothwell NJ, Hopkins SJ. (2005). Correlation of systemic inflammatory response with infarct volume in acute ischemic stroke patients. Stroke; a journal of cerebral circulation, 36(2), 228-9; author reply 228-9. eScholarID:1c4615 | PMID:15625287 | DOI:10.1161/01.STR.0000155197.88944.ac
Emsley, HCA, Smith, CJ, Georgiou, R, Vail, A, Tyrrell, PJ, Barberan, EM, Rothwell, NJ, Hopkins, SJ, Audebert, H, Haberl, RL. (2005). Correlation of systemic inflammatory response with infarct volume in acute ischemic stroke patients. Stroke, 36( 2), eScholarID:17d511
Andre R, Pinteaux E, Kimber I, Rothwell NJ. (2005). Differential actions of IL-1 alpha and IL-1 beta in glial cells share common IL-1 signalling pathways. Neuroreport, 16(2), 153-7. eScholarID:1c4609 | PMID:15671867 | DOI:10.1097/00001756-200502080-00017
Allan S, Tyrrell PJ, Rothwell NJ. (2005). Interleukin-1 and neuronal injury. Nat Rev Immunol, 5( 8), eScholarID:1d31190
Emsley H, Smith CJ, Georgiu R, Vail A, Barberan EM, Rothwell NJ, Tyrrell PJ, Hopkins SJ. (2005). Interleukin-6 and acute ischaemic stroke. Acta Neurol Scand, 112( 4), eScholarID:17d504
Molina-Holgado F, Pinteaux E, Heenan L, Moore JD, Rothwell NJ, Gibson RM. (2005). Neuroprotective effects of the synthetic cannabinoid HU-210 in primary cortical neurons are mediated by phosphatidylinositol 3-kinase/AKT signaling. Molecular and cellular neurosciences, 28(1), 189-94. eScholarID:1c4610 | PMID:15607953 | DOI:10.1016/j.mcn.2004.09.004
Andre R, Lerouet D, Kimber I, Pinteaux E, Rothwell NJ. (2005). Regulation of expression of the novel IL-1 receptor family members in the mouse brain. Journal of neurochemistry, 95(2), 324-30. eScholarID:1c4607 | PMID:16086690 | DOI:10.1111/j.1471-4159.2005.03364.x
Wang P, Meinhardt B, Andre R, Renshaw BR, Kimber I, Rothwell NJ, Pinteaux E. (2005). The interleukin-1-related cytokine IL-1F8 is expressed in glial cells, but fails to induce IL-1beta signalling responses. Cytokine, 29(6), 245-50. eScholarID:1c4613 | PMID:15749024
2004
Gibson RM, Rothwell NJ, Le Feuvre RA. (2004). CNS injury: the role of the cytokine IL-1. Veterinary journal (London, England : 1997), 168(3), 230-7. eScholarID:1c4611 | PMID:15501140 | DOI:10.1016/j.tvjl.2003.10.016
Smith, C, Emsley, H, Gavin, C, Georgiou, R, Vail, A, Barberan, E, Del Zoppo, G, Hallenbeck, J, Rothwell, NJ, Hopkins, S, Tyrrell, P. (2004). Correction: Peak plasma interleukin-6 and other peripheral markers of inflammation in the first week of ischaemic stroke correlate with brain infarct volume, stroke severity and long-term outcome. BMC Neurol, 4( 1), eScholarID:1d29083
Smith, CJ, Emsley, HCA, Gavin, C, Georgiou, R, Vail, A, Barberan, EM, Del Zoppo, G, Hallenbeck, J, Rothwell, NJ, Hopkins, SJ, Tyrrell, PJ. (2004). Peak Plasma Interleukin-6 and Other Periperhal Markers of Inflammation in tne first week of Ischaemic Stroke Correlate with Brain Infarct Volume, Stroke Severity and Long-term Outcome. BMC Neurology, Jan 15; 4:2, eScholarID:1d7414 | DOI:10.1186/1471-2377-4-2
Smith CJ, Emsley HC, Gavin CM, Georgiou RF, Vail A, Barberan EM, Del Zoppo GJ, Hallenbeck JM, Rothwell NJ, Hopkins SJ, Tyrrell PJ. (2004). Peak plasma interleukin-6 and other peripheral markers of inflammation in the first week of ischaemic stroke correlate with brain infarct volume, stroke severity and long-term outcome. BMC Neurology, 4(1), 2. eScholarID:1c2892
2003
Ross F, Allan S, Rothwell NJ, Verkhratsky A. (2003). A dual role for interleukin-1 in LTP in mouse hippocampal slices. J Neuroimmunol, 144( 1-2), 61-7. eScholarID:1d28997
Verkhratsky A, Rothwell NJ, Ross FM, Allan SM. (2003). A dual role for interleukin-1 in LTP in mouse hippocampal slices. Journal of neuroimmunology, 144(1-2), 61-67. eScholarID:1c83 | PMID:14597099 | DOI:10.1016/j.jneuroim.2003.08.030
Rothwell N.J., Emsley H.C., Smith C.J., Barberan E.M., Tyrrell P.J., Gavin C.M., Hopkins S.J., Vail A., Georgiou R.F., Hallenbeck J.M., Del Zoppo G.J. (2003). An early and sustained peripheral inflammatory response in acute ischaemic stroke: relationships with infection and atherosclerosis. Journal of neuroimmunology, 139(1-2), 93-101. eScholarID:1c316 | DOI:10.1016/S0165-5728(03)00134-6
Emsley, HCA, Smith, CJ, Gavin,C.M., Georgiou, R, Vail, A, Barberan,E.M., Hallenbeck,J.M., del Zoppo,G.J., Rothwell, NJ, Tyrrell, PJ, Hopkins, SJ. (2003). An early and sustained peripheral inflammatory response in acute ischaemic stroke: relationships with infection and atherosclerosis. Journal of Neuroimmunology, 139, 1-2, 93-101. eScholarID:1d5582 | DOI:10.1016/S0165-5728(03)00134-6
Brough D, Le Feuvre RA, Wheeler RD, Solovyova N, Hilfiker S, Rothwell NJ, Verkhratsky A. (2003). Ca(2+) Stores and Ca(2+) Entry Differentially Contribute to the Release of IL-1beta and IL-1alpha from Murine Macrophages. Journal of immunology (Baltimore, Md. : 1950), 170(6), 3029-3036. eScholarID:1c315
Brough D, Le Feuvre R, Wheeler R, Solovyova N, Hilfiker S, Rothwell NJ, Verkhratsky A. (2003). Ca2+ stores and Ca2+ entry differentially contribute to the release of IL-1 beta and IL-1 alpha from murine macrophages. J Immunol, 170( 6), 3029-36. eScholarID:1d28929
Mulcahy N, Ross J, Rothwell NJ, Loddick S. (2003). Delayed administration of interleukin-1 receptor antagonist protects against transient cerebral ischaemia in the rat. Br J Pharmacol, 140( 3), 471-6. eScholarID:1d28998
Mulcahy NJ, Ross J, Rothwell NJ, Loddick SA. (2003). Delayed administration of interleukin-1 receptor antagonist protects against transient cerebral ischaemia in the rat. British journal of pharmacology, 140, 471-476. eScholarID:1c2378 | DOI:10.1038/sj.bjp.0705462
Molina-Holgado F, Pinteaux E, Moore JD, Molina-Holgado E, Guaza C, Gibson RM, Rothwell NJ. (2003). Endogenous interleukin-1 receptor antagonist mediates anti-inflammatory and neuroprotective actions of cannabinoids in neurones and glia. Journal of Neuroscience, 23, 6470-6474. eScholarID:1c2376
Molina-Holgado F, Pinteaux E, Moore J, Molina-Holgado E, Guaza C, Gibson R, Rothwell NJ. (2003). Endogenous interleukin-1 receptor antagonist mediates anti-inflammatory and neuroprotective actions of cannabinoids in neurons and glia. J Neurosci, 23( 16), 6470-4. eScholarID:1d28928
Berglof E, Andre R, Renshaw BR, Allan SM, Lawrence CB, Rothwell NJ, Pinteaux E. (2003). IL-1Rrp2 expression and IL-1F9 (IL-1H1) actions in brain cells. Journal of neuroimmunology, 139(1-2), 36-43. eScholarID:1c314 | DOI:10.1016/S0165-5728(03)00130-9
Berglöf E, Andre R, Renshaw B, Allan S, Lawrence C, Rothwell NJ, Pinteaux E. (2003). IL-1Rrp2 expression and IL-1F9 (IL-1H1) actions in brain cells. J Neuroimmunol, 139(1-2), 36-43. eScholarID:1d28557 | DOI:10.1016/S0165-5728(03)00130-9
Andre R, Wheeler RD, Collins PD, Luheshi GN, Pickering-Brown S, Kimber I, Rothwell NJ, Pinteaux E. (2003). Identification of a truncated IL-18R beta mRNA: a putative regulator of IL-18 expressed in rat brain. Journal of neuroimmunology, 145(1-2), 40-5. eScholarID:1c4666 | PMID:14644029 | DOI:10.1016/j.jneuroim.2003.09.005
Andre R, Wheeler R, Collins P, Luheshi G, Pickering-Brown S, Kimber I, Rothwell NJ, Pinteaux E. (2003). Identification of a truncated IL-18R beta mRNA: a putative regulator of IL-18 expressed in rat brain. J Neuroimmunol, 145( 1-2), 40-5. eScholarID:1d28927
Allan S, Rothwell NJ. (2003). Inflammation in central nervous system injury. Philos Trans R Soc Lond B Biol Sci, 358( 1438), 1669-77. eScholarID:1d28575
Allan SM, Rothwell NJ. (2003). Inflammation in central nervous system injury. Philosophical Transactions of the Royal Society (London), 358(1438), 1669-1677. eScholarID:1c84 | PMID:14561325 | DOI:10.1098/rstb.2003.1358
Rothwell NJ. (2003). Interleukin-1 and neuronal injury: mechanisms, modification and therapeutic potential. Brain, Bahaviour and Immunity, 17, 152-157. eScholarID:1c2379 | DOI:10.1016/S0889-1591(02)00098-3
Rothwell NJ. (2003). Interleukin-1 and neuronal injury: mechanisms, modification, and therapeutic potential. Brain Behav Immun, 17( 3), 152-7. eScholarID:1d29722
Wheeler R, Brough D, Le Feuvre R, Takeda K, Iwakura Y, Luheshi G, Rothwell NJ. (2003). Interleukin-18 induces expression and release of cytokines from murine glial cells: interactions with interleukin-1 beta. J Neurochem, 85( 6), 1412-20. eScholarID:1d28582
Wheeler RD, Brough D, Le Feuvre RA, Takeda K, Iwakura Y, Luheshi GN, Rothwell NJ. (2003). Interleukin-18 induces expression and release of cytokines from murine glial cells: interactions with interleukin-1beta. Journal of neurochemistry, 85(6), 1412-1420. eScholarID:1c322 | DOI:10.1046/j.1471-4159.2003.01787.x
Wheeler R, Boutin H, Touzani O, Luheshi G, Takeda K, Rothwell NJ. (2003). No role for interleukin-18 in acute murine stroke-induced brain injury. J Cereb Blood Flow Metab, 23( 5), 531-5. eScholarID:1d29005
Wheeler RD, Boutin H, Touzani O, Luheshi GN, Takeda K, Rothwell NJ. (2003). No role for interleukin-18 in acute murine stroke-induced brain injury. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 23(5), 531-5. eScholarID:1c4665 | PMID:12771567
Le Feuvre RA, Brough D, Touzani O, Rothwell NJ. (2003). Role of P2X7 receptors in ischemic and excitotoxic brain injury in vivo. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 23(3), 381-4. eScholarID:1c79 | PMID:12621313
Le Feuvre R, Brough D, Touzani O, Rothwell NJ. (2003). Role of P2X7 receptors in ischemic and excitotoxic brain injury in vivo. J Cereb Blood Flow Metab, 23( 3), 381-4. eScholarID:1d29006
Boutin H, Kimber I, Rothwell NJ, Pinteaux E. (2003). The expanding interleukin-1 family and its receptors: do alternative IL-1 receptor/signaling pathways exist in the brain? Mol Neurobiol, 27( 3), 239-48. eScholarID:1d28544
Boutin H, Kimber I, Rothwell NJ, Pinteaux E. (2003). The expanding interleukin-1 family and its receptors: do alternative IL-1 receptor/signalling pathways exist in the brain? Molecular neurobiology, 27, 239-248. eScholarID:1c2377 | DOI:10.1385/MN:27:3:239
Wheeler R, Young E, Rothwell NJ, Hall M, Luheshi G. (2003). Up-regulation of IL-18BP, but not IL-18 mRNA in rat liver by LPS. Cytokine, 21( 4), 161-6. eScholarID:1d28558
Wheeler RD, Young EA, Rothwell NJ, Hall MD, Luheshi GN. (2003). Up-regulation of IL-18BP, but not IL-18 mRNA in rat liver by LPS. Cytokine, 21(4), 161-6. eScholarID:1c4669 | PMID:12788303 | DOI:10.1016/S1043-4666(03)00028-0
2002
Pinteaux E., Parker L.C., Rothwell N.J., Luheshi G.N. (2002). Expression of interleukin-1 receptors and their role in interleukin-1 actions in murine microglial cells. Journal of neurochemistry, 83, 754-763. eScholarID:1c541 | DOI:10.1046/j.1471-4159.2002.01184.x
Pinteaux E, Parker L, Rothwell NJ, Luheshi G. (2002). Expression of interleukin-1 receptors and their role in interleukin-1 actions in murine microglial cells. J Neurochem, 83( 4), 754-63. eScholarID:1d29084
Le Feuvre R, Brough D, Rothwell N. (2002). Extracellular ATP and P2X7 receptors in neurodegeneration. European journal of pharmacology, 447(2-3), 261-9. eScholarID:1c80 | PMID:12151017 | DOI:10.1016/S0014-2999(02)01848-4
Parker L.C., Luheshi G.N., Rothwell N.J., Pinteaux E. (2002). IL-1 beta signalling in glial cells in wildtype and IL-1RI deficient mice. British journal of pharmacology, 136, 312-320. eScholarID:1c538 | DOI:10.1038/sj.bjp.0704715
Parker L, Luheshi G, Rothwell NJ, Pinteaux E. (2002). IL-1 beta signalling in glial cells in wildtype and IL-1RI deficient mice. Br J Pharmacol, 136( 2), 312-20. eScholarID:1d28438
Touzani O, Boutin H, LeFeuvre R, Parker L, Miller A, Luheshi G, Rothwell N. (2002). Interleukin-1 influences ischemic brain damage in the mouse independently of the interleukin-1 type I receptor. Journal of Neuroscience, 22(1), 38-43. eScholarID:1c81 | PMID:11756486
Moore J.D., Rothwell N.J., Gibson R.M. (2002). Involvement of caspases and calpains in cerebrocortical neuronal cell death is stimulus-dependent. British journal of pharmacology, 135, 1069-1077. eScholarID:1c318 | DOI:10.1038/sj.bjp.0704538
Moore J, Rothwell NJ, Gibson R. (2002). Involvement of caspases and calpains in cerebrocortical neuronal cell death is stimulus-dependent. Br J Pharmacol, 135( 4), 1069-77. eScholarID:1d28439
Ellacott K.L., Lawrence C.B., Rothwell N.J., Luckman S.M. (2002). PRL-releasing peptide interacts with leptin to reduce food intake and body weight. Endocrinology, 143, 368-374. eScholarID:1c482 | DOI:10.1210/en.143.2.368
Ellacott K, Lawrence C, Rothwell NJ, Luckman S. (2002). PRL-releasing peptide interacts with leptin to reduce food intake and body weight. Endocrinology, 143( 2), 368-74. eScholarID:1d28930
Le Feuvre R.A., Brough D., Iwakura Y., Takeda K., Rothwell N.J. (2002). Priming of macrophages with lipopolysaccharide potentiates P2X7-mediated cell death via a caspase-1-dependent mechanism, independently of cytokine production. Journal of Biological Chemistry, 277, 3210-3218. eScholarID:1c317 | DOI:10.1074/jbc.M104388200
Le Feuvre R, Brough D, Iwakura Y, Takeda K, Rothwell NJ. (2002). Priming of macrophages with lipopolysaccharide potentiates P2X7-mediated cell death via a caspase-1-dependent mechanism, independently of cytokine production. J Biol Chem, 277( 5), 3210-8. eScholarID:1d28565
Brough D., Le Feuvre R.A., Iwakura Y., Rothwell N.J. (2002). Purinergic (P2X7) receptor activation of microglia induces cell death via an interleukin-1-independent mechanism. Molecular and cellular neurosciences, 19, 272-280. eScholarID:1c446 | DOI:10.1006/mcne.2001.1054
Brough D, Le Feuvre R, Iwakura Y, Rothwell NJ. (2002). Purinergic (P2X7) receptor activation of microglia induces cell death via an interleukin-1-independent mechanism. Mol Cell Neurosci, 19( 2), 272-80. eScholarID:1d29724
Molina-Holgado F., Molina-Holgado E., Guaza C., Rothwell N.J. (2002). Role of CB1 and CB2 receptors in the inhibitory effects of cannabinoids on lipopolysaccharide-induced nitric oxide release in astrocyte cultures. Journal of neuroscience research, 67, 829-836. eScholarID:1c533 | DOI:10.1002/jnr.10165
Molina-Holgado F, Molina-Holgado E, Guaza C, Rothwell NJ. (2002). Role of CB1 and CB2 receptors in the inhibitory effects of cannabinoids on lipopolysaccharide-induced nitric oxide release in astrocyte cultures. J Neurosci Res, 67( 6), 829-36. eScholarID:1d29085
Grundy R.I., Rothwell N.J., Allan S.M. (2002). Site-specific actions of interleukin-1 on excitotoxic cell death in the rat striatum. Brain research, 926, 142-148. eScholarID:1c490 | DOI:10.1016/S0006-8993(01)03325-X
Grundy R, Rothwell NJ, Allan S. (2002). Site-specific actions of interleukin-1 on excitotoxic cell death in the rat striatum. Brain Res, 926( 1-2), 142-8. eScholarID:1d29120
Oakden E, Chiswick M, Rothwell N, Loddick S. (2002). The influence of litter size on brain damage caused by hypoxic-ischemic injury in the neonatal rat. Pediatric research, 52(5), 692-6. eScholarID:1c4682 | PMID:12409515 | DOI:10.1203/00006450-200211000-00014
Molina-Holgado F, Grencis R, Rothwell NJ. (2001). Actions of exogenous and endogenous IL-10 on glial responses to bacterial LPS/cytokines. Glia, 33( 2), 97-106. eScholarID:1d28584
Lawrence C, Rothwell NJ. (2001). Anorexic but not pyrogenic actions of interleukin-1 are modulated by central melanocortin-3/4 receptors in the rat. J Neuroendocrinol, 13( 6), 490-5. eScholarID:1d29726
Lawrence CB, Rothwell NJ. (2001). Anorexic but not pyrogenic actions of interleukin-1 are modulated by central melanocortin-3/4 receptors in the rat. Journal of neuroendocrinology, 13(6), 490-5. eScholarID:1c4681 | PMID:11412335 | DOI:10.1046/j.1365-2826.2001.00660.x
Allan SS.M, Rothwell NJ. (2001). Cytokines and acute neurodegeneration. Nat Rev Neurosci, eScholarID:1d33059
Allan S.M., Rothwell N.J. (2001). Cytokines and acute neurodegeneration. Nature reviews. Neuroscience, 2, 734-744. eScholarID:1c431 | DOI:10.1038/35094583
Allan S, Rothwell NJ. (2001). Cytokines and acute neurodegeneration. Nat Rev Neurosci, 2( 10), 734-44. eScholarID:1d28545
Craighead M.W., Middlehurst K.M., LeFeuvre R., Kimber I., Rothwell N.J. (2001). Oxidised adenosine 5"-triphosphate, a P2X(7) antagonist, is toxic to rat cerebellar granule neurones in vitro. Neuroscience letters, 311, 77-80. eScholarID:1c475 | DOI:10.1016/S0304-3940(01)02110-3
Craighead M, Middlehurst K, LeFeuvre R, Kimber I, Rothwell NJ. (2001). Oxidised adenosine 5'-triphosphate, a P2X(7) antagonist, is toxic to rat cerebellar granule neurones in vitro. Neurosci Lett, 311( 2), 77-80. eScholarID:1d28546
Boutin H., LeFeuvre R.A., Horai R., Asano M., Iwakura Y., Rothwell N.J. (2001). Role of IL-1alpha and IL-1beta in ischemic brain damage. Journal of Neuroscience, 21, 5528-5534. eScholarID:1c442
Boutin H, LeFeuvre R, Horai R, Asano M, Iwakura Y, Rothwell NJ. (2001). Role of IL-1alpha and IL-1beta in ischemic brain damage. J Neurosci, 21( 15), 5528-34. eScholarID:1d28936
Cartmell T., Luheshi G.N., Hopkins S.J., Rothwell N.J., Poole S. (2001). Role of endogenous interleukin-1 receptor antagonist in regulating fever induced by localised inflammation in the rat. Journal of physiology, Paris, 531, 171-180. eScholarID:1c459
Cartmell T, Luheshi GG, Hopkins SJ, Rothwell NJ, Poole S. (2001). Role of endogenous interleukin-1 receptor antagonist in regulating fever induced by localised inflammation in the rat. J Physiol, 531( Pt 1), 171-80. eScholarID:1d7832
Allan S.M., Harrison D.C., Read S., Collins B., Parsons A.A., Philpott K., Rothwell N.J. (2001). Selective increases in cytokine expression in the rat brain in response to striatal injection of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate and interleukin-1. Brain research. Molecular brain research, 93, 180-189. eScholarID:1c432
Allan S, Harrison D, Read S, Collins B, Parsons A, Philpott K, Rothwell NJ. (2001). Selective increases in cytokine expression in the rat brain in response to striatal injection of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate and interleukin-1. Brain Res Mol Brain Res, 93( 2), 180-9. eScholarID:1d28566
Rothwell NJ. (2001). Thermogenesis: where are we and where are we going? Report of a workshop held in London 21st April 2001, convened by Professor Mike Stock. Int J Obes Relat Metab Disord, 25( 9), 1272-4. eScholarID:1d28926
2000
Cartmell T., Poole S., Turnbull A.V., Rothwell N.J., Luheshi G.N. (2000). Circulating interleukin-6 mediates the febrile response to localised inflammation in rats. Journal of physiology, Paris, 526 Pt 3, 653. eScholarID:1c458
Cartmell T, Poole S, Turnbull A, Rothwell NJ, Luheshi G. (2000). Circulating interleukin-6 mediates the febrile response to localised inflammation in rats. J Physiol, 526 Pt 3, 653-61. eScholarID:1d28585
Allan S.M., Parker L.C., Collins B., Davies R., Luheshi G.N., Rothwell N.J. (2000). Cortical cell death induced by IL-1 is mediated via actions in the hypothalamus of the rat. Proc.Natl.Acad.Sci.U.S.A, 97, 5580. eScholarID:1c429
Allan S, Parker L, Collins B, Davies R, Luheshi G, Rothwell NJ. (2000). Cortical cell death induced by IL-1 is mediated via actions in the hypothalamus of the rat. Proc Natl Acad Sci U S A, 97( 10), 5580-5. eScholarID:1d29008
Allan S.M., Rothwell N.J. (2000). Cortical death caused by striatal administration of AMPA and interleukin-1 is mediated by activation of cortical NMDA receptors. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 20, 1409. eScholarID:1c430
Allan S, Rothwell NJ. (2000). Cortical death caused by striatal administration of AMPA and interleukin-1 is mediated by activation of cortical NMDA receptors. J Cereb Blood Flow Metab, 20( 10), 1409-13. eScholarID:1d28440
Wheeler R.D., Culhane A.C., Hall M.D., Pickering-Brown S., Rothwell N.J., Luheshi G.N. (2000). Detection of the interleukin 18 family in rat brain by RT-PCR. Brain research. Molecular brain research, 77, 290. eScholarID:1c683
Wheeler R, Culhane A, Hall M, Pickering-Brown S, Rothwell NJ, Luheshi G. (2000). Detection of the interleukin 18 family in rat brain by RT-PCR. Brain Res Mol Brain Res, 77( 2), 290-3. eScholarID:1d28938
Parker L.C., Rushforth D.A., Rothwell N.J., Luheshi G.N. (2000). IL-1beta induced changes in hypothalamic IL-1R1 and IL-1R2 mRNA expression in the rat. Brain research. Molecular brain research, 79, 156. eScholarID:1c537
Parker L, Rushforth D, Rothwell NJ, Luheshi G. (2000). IL-1beta induced changes in hypothalamic IL-1R1 and IL-1R2 mRNA expression in the rat. Brain Res Mol Brain Res, 79( 1-2), 156-8. eScholarID:1d28441
Craighead M.W., Boutin H., Middlehurst K.M., Allan S.M., Brooks N., Kimber I., Rothwell N.J. (2000). Influence of corticotrophin releasing factor on neuronal cell death in vitro and in vivo. Brain research, 881, 139. eScholarID:1c474
Craighead M, Boutin H, Middlehurst K, Allan S, Brooks N, Kimber I, Rothwell NJ. (2000). Influence of corticotrophin releasing factor on neuronal cell death in vitro and in vivo. Brain Res, 881( 2), 139-43. eScholarID:1d29188
Zampronio A.R., Hoadley M.E., Luheshi G., Rothwell N.J., De Souza G.E., Hopkins S.J. (2000). Interleukin (IL)-6 release and fever induced by a pre-formed pyrogenic factor (PFPF) derived from LPS-stimulated macrophages. Eur.Cytokine Netw, 11, 589. eScholarID:1c687
Zampronio A, Hoadley M, Luheshi GG, Rothwell NJ, de Souza G, Hopkins SJ. (2000). Interleukin (IL)-6 release and fever induced by a pre-formed pyrogenic factor (PFPF) derived from LPS-stimulated macrophages. Eur Cytokine Netw, 11( 4), 589-96. eScholarID:1d16905
Rothwell NJ, Luheshi G. (2000). Interleukin 1 in the brain: biology, pathology and therapeutic target. Trends Neurosci, 23( 12), 618-25. eScholarID:1d28937
Rothwell N.J., Luheshi G.N. (2000). Interleukin-1 in the brain: biology, pathology and therapeutic target. Trends in neurosciences, 23, 618. eScholarID:1c660
Molina-Holgado F., Toulmond S., Rothwell N.J. (2000). Involvement of interleukin-1 in glial responses to lipopolysaccharide: endogenous versus exogenous interleukin-1 actions. Journal of neuroimmunology, 111, 1. eScholarID:1c531
Molina-Holgado F, Toulmond S, Rothwell NJ. (2000). Involvement of interleukin-1 in glial responses to lipopolysaccharide: endogenous versus exogenous interleukin-1 actions. J Neuroimmunol, 111( 1-2), 1-9. eScholarID:1d29187
Rothwell N.J. (2000). Show them how it"s really done. Nature, 405, 621. eScholarID:1c661
Rothwell NJ. (2000). Show them how it's really done. Nature, 405( 6787), eScholarID:1d29007
Rothwell N.J. (1999). Annual review prize lecture. Cytokines - killers in the brain? Journal of physiology, Paris, 514 (Pt 1), 3. eScholarID:1c658
Cartmell T., Luheshi G.N., Rothwell N.J. (1999). Brain sites of action of endogenous interleukin-1 in the febrile response to localized inflammation in the rat. Journal of physiology, Paris, 518 ( Pt 2), 585. eScholarID:1c457
Cartmell T, Luheshi G, Rothwell NJ. (1999). Brain sites of action of endogenous interleukin-1 in the febrile response to localized inflammation in the rat. J Physiol, 518 ( Pt 2), 585-94. eScholarID:1d28948
Lenczowski M.J., Bluthe R.M., Roth J., Rees G.S., Rushforth D.A., van Dam A.M., Tilders F.J., Dantzer R., Rothwell N.J., Luheshi G.N. (1999). Central administration of rat IL-6 induces HPA activation and fever but not sickness behavior in rats. Am.J.Physiol, 276, R652. eScholarID:1c513
Rothwell N.J. (1999). Cytokines "Killers in the Brain". Journal of physiology, Paris, 514.1, 3. eScholarID:1c659
Grundy R.I., Rothwell N.J., Allan S.M. (1999). Dissociation between the effects of interleukin-1 on excitotoxic brain damage and body temperature in the rat. Brain research, 830, 32. eScholarID:1c489
Grundy R, Rothwell NJ, Allan S. (1999). Dissociation between the effects of interleukin-1 on excitotoxic brain damage and body temperature in the rat. Brain Res, 830( 1), 32-7. eScholarID:1d28939
Pearson V.L., Rothwell N.J., Toulmond S. (1999). Excitotoxic brain damage in the rat induces interleukin-1beta protein in microglia and astrocytes: correlation with the progression of cell death. Glia, 25, 311. eScholarID:1c539
Pearson V, Rothwell NJ, Toulmond S. (1999). Excitotoxic brain damage in the rat induces interleukin-1beta protein in microglia and astrocytes: correlation with the progression of cell death. Glia, 25( 4), 311-23. eScholarID:1d29010
Lawrence C.B., Turnbull A.V., Rothwell N.J. (1999). Hypothalamic control of feeding. Curr.Opin.Neurobiol, 9, 778. eScholarID:1c508
Lawrence C, Turnbull A, Rothwell NJ. (1999). Hypothalamic control of feeding. Curr Opin Neurobiol, 9( 6), 778-83. eScholarID:1d28547
Luheshi G.N., Gardner J.D., Rushforth D.A., Loudon A.S., Rothwell N.J. (1999). Leptin actions on food intake and body temperature are mediated by IL-1. Proc.Natl.Acad.Sci.U.S.A, 96, 7047. eScholarID:1c522
Luheshi G, Gardner J, Rushforth D, Loudon A, Rothwell NJ. (1999). Leptin actions on food intake and body temperature are mediated by IL-1. Proc Natl Acad Sci U S A, 96( 12), 7047-52. eScholarID:1d29009
Loddick S.A., Rothwell N.J. (1999). Mechanisms of tumor necrosis factor alpha action on neurodegeneration: interaction with insulin-like growth factor-1. Proc.Natl.Acad.Sci.U.S.A, 96, 9449. eScholarID:1c518
Loddick S, Rothwell NJ. (1999). Mechanisms of tumor necrosis factor alpha action on neurodegeneration: interaction with insulin-like growth factor-1. Proc Natl Acad Sci U S A, 96( 17), 9449-51. eScholarID:1d28568
Davies C.A., Loddick S.A., Toulmond S., Stroemer R.P., Hunt J., Rothwell N.J. (1999). The progression and topographic distribution of interleukin-1beta expression after permanent middle cerebral artery occlusion in the rat. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 19, 87. eScholarID:1c480
Davies CA, Loddick S, Toulmond S, Stroemer R, Hunt J, Rothwell NJ. (1999). The progression and topographic distribution of interleukin-1beta expression after permanent middle cerebral artery occlusion in the rat. J Cereb Blood Flow Metab, 19( 1), 87-98. eScholarID:1d28586
Artis D., Humphreys N.E., Bancroft A.J., Rothwell N.J., Potten C.S., Grencis R.K. (1999). Tumor necrosis factor alpha is a critical component of interleukin 13-mediated protective T helper cell type 2 responses during helminth infection. J.Exp.Med, 190, 953. eScholarID:1c438
Artis D, Humphreys N, Bancroft A, Rothwell NJ, Potten C, Grencis R. (1999). Tumor necrosis factor alpha is a critical component of interleukin 13-mediated protective T helper cell type 2 responses during helminth infection. J Exp Med, 190( 7), 953-62. eScholarID:1d28567
1998
Davies C.A., Loddick S.A., Stroemer R.P., Hunt J., Rothwell N.J. (1998). An integrated analysis of the progression of cell responses induced by permanent focal middle cerebral artery occlusion in the rat. Exp.Neurol, 154, 199. eScholarID:1c479
Davies CA, Loddick S, Stroemer R, Hunt J, Rothwell NJ. (1998). An integrated analysis of the progression of cell responses induced by permanent focal middle cerebral artery occlusion in the rat. Exp Neurol, 154( 1), 199-212. eScholarID:1d28583
Anforth H.R., Bluthe R.M., Bristow A., Hopkins S., Lenczowski M.J., Luheshi G., Lundkvist J., Michaud B., Mistry Y., van Dam A.M., Zhen C., Dantzer R., Poole S., Rothwell N.J., Tilders F.J., Wollman E.E. (1998). Biological activity and brain actions of recombinant rat interleukin-1alpha and interleukin-1beta. Eur.Cytokine Netw, 9, 279. eScholarID:1c435
Anforth, H, Bluthe, R, Bristow, A, Hopkins, S, Lenczowski, M, Luheshi, G, Lundkvist, J, Michaud, B, Mistry, Y, Van Dam, A, Zhen, C, Dantzer, R, Poole, S, Rothwell, NJ, Tilders, F, Wollman, E. (1998). Biological activity and brain actions of recombinant rat interleukin-1alpha and interleukin-1beta. Eur Cytokine Netw, 9( 3), 279-88. eScholarID:1d28442
Ochu E.E., Rothwell N.J., Waters C.M. (1998). Caspases mediate 6-hydroxydopamine-induced apoptosis but not necrosis in PC12 cells. Journal of neurochemistry, 70, 2637. eScholarID:1c536
Ochu E, Rothwell NJ, Waters C. (1998). Caspases mediate 6-hydroxydopamine-induced apoptosis but not necrosis in PC12 cells. J Neurochem, 70( 6), 2637-40. eScholarID:1d29727
Loddick S.A., Turnbull A.V., Rothwell N.J. (1998). Cerebral interleukin-6 is neuroprotective during permanent focal cerebral ischemia in the rat. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 18, 176. eScholarID:1c517
Loddick S, Turnbull A, Rothwell NJ. (1998). Cerebral interleukin-6 is neuroprotective during permanent focal cerebral ischemia in the rat. J Cereb Blood Flow Metab, 18( 2), 176-9. eScholarID:1d29728
Culhane A.C., Hall M.D., Rothwell N.J., Luheshi G.N. (1998). Cloning of rat brain interleukin-18 cDNA. Mol.Psychiatry, 3, 362. eScholarID:1c476
Culhane A, Hall M, Rothwell NJ, Luheshi G. (1998). Cloning of rat brain interleukin-18 cDNA. Mol Psychiatry, 3( 4), 362-6. eScholarID:1d29190
Huitinga I., Bauer J., Strijbos P.J., Rothwell N.J., Dijkstra C.D., Tilders F.J. (1998). Effect of annexin-1 on experimental autoimmune encephalomyelitis (EAE) in the rat. Clin.Exp.Immunol, 111, 198. eScholarID:1c502
Roe S.Y., McGowan E.M., Rothwell N.J. (1998). Evidence for the involvement of corticotrophin-releasing hormone in the pathogenesis of traumatic brain injury. Eur.J.Neurosci, 10, 553. eScholarID:1c549
Roe S, McGowan E, Rothwell NJ. (1998). Evidence for the involvement of corticotrophin-releasing hormone in the pathogenesis of traumatic brain injury. Eur J Neurosci, 10( 2), 553-9. eScholarID:1d28443
Stroemer R.P., Rothwell N.J. (1998). Exacerbation of ischemic brain damage by localized striatal injection of interleukin-1beta in the rat. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 18, 833. eScholarID:1c678
Stroemer R, Rothwell NJ. (1998). Exacerbation of ischemic brain damage by localized striatal injection of interleukin-1beta in the rat. J Cereb Blood Flow Metab, 18( 8), 833-9. eScholarID:1d28450
Allan S.M., Lawrence C.B., Rothwell N.J. (1998). Interleukin-1 beta and interleukin-1 receptor antagonist do not affect glutamate release or calcium entry in rat striatal synaptosomes. Mol.Psychiatry, 3, 178. eScholarID:1c428
Allan S, Lawrence C, Rothwell NJ. (1998). Interleukin-1 beta and interleukin-1 receptor antagonist do not affect glutamate release or calcium entry in rat striatal synaptosomes. Mol Psychiatry, 3( 2), 178-82. eScholarID:1d28587
Lawrence C.B., Allan S.M., Rothwell N.J. (1998). Interleukin-1beta and the interleukin-1 receptor antagonist act in the striatum to modify excitotoxic brain damage in the rat. Eur.J.Neurosci, 10, 1188. eScholarID:1c507
Lawrence C, Allan S, Rothwell NJ. (1998). Interleukin-1beta and the interleukin-1 receptor antagonist act in the striatum to modify excitotoxic brain damage in the rat. Eur J Neurosci, 10( 3), 1188-95. eScholarID:1d29189
Cartmell T., Poole S., Rothwell N.J., Luheshi G.N. (1998). Relationship between interleukin-1 and interleukin-1 receptor antagonist during the development of fever in the rat. Ann.N.Y.Acad.Sci, 856, 252. eScholarID:1c456
Cartmell T, Poole S, Rothwell NJ, Luheshi G. (1998). Relationship between interleukin-1 and interleukin-1 receptor antagonist during the development of fever in the rat. Ann N Y Acad Sci, 856, 252-5. eScholarID:1d29725
1997
Rothwell N.J., Stock M.J. (1997). A role for brown adipose tissue in diet-induced thermogenesis. Obes.Res, 5, 650. eScholarID:1c654
Stroemer R.P., Rothwell N.J. (1997). Cortical protection by localized striatal injection of IL-1ra following cerebral ischemia in the rat. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 17, 597. eScholarID:1c677
Stroemer R, Rothwell NJ. (1997). Cortical protection by localized striatal injection of IL-1ra following cerebral ischemia in the rat. J Cereb Blood Flow Metab, 17( 6), 597-604. eScholarID:1d28949
Loddick S.A., Wong M.L., Bongiorno P.B., Gold P.W., Licinio J., Rothwell N.J. (1997). Endogenous interleukin-1 receptor antagonist is neuroprotective. Biochemical and biophysical research communications, 234, 211. eScholarID:1c516
Loddick S, Wong M, Bongiorno P, Gold P, Licinio J, Rothwell NJ. (1997). Endogenous interleukin-1 receptor antagonist is neuroprotective. Biochem Biophys Res Commun, 234( 1), 211-5. eScholarID:1d28569
Luheshi G.N., Stefferl A., Turnbull A.V., Dascombe M.J., Brouwer S., Hopkins S.J., Rothwell N.J. (1997). Febrile response to tissue inflammation involves both peripheral and brain IL-1 and TNF-alpha in the rat. Am.J.Physiol, 272, R862. eScholarID:1c521
Luheshi G, Stefferl A, Turnbull A, Dascombe M, Brouwer S, Hopkins S, Rothwell NJ. (1997). Febrile response to tissue inflammation involves both peripheral and brain IL-1 and TNF-alpha in the rat. Am J Physiol, 272( 3 Pt 2), R862-8. eScholarID:1d29729
Rothwell N.J., Loddick S.A., Stroemer P. (1997). Interleukins and cerebral ischaemia. Int.Rev.Neurobiol, 40, 281. eScholarID:1c656
Rothwell NJ, Loddick S, Stroemer P. (1997). Interleukins and cerebral ischaemia. Int Rev Neurobiol, 40, 281-98. eScholarID:1d29730
Roe S.Y., Cooper A.L., Morris I.D., Hopkins S.J., Rothwell N.J. (1997). Involvement of cytokines in cachexia induced by T-cell leukaemia in the rat. Eur.Cytokine Netw, 8, 45. eScholarID:1c546
Roe S, Cooper A, Morris I, Hopkins S, Rothwell NJ. (1997). Involvement of cytokines in cachexia induced by T-cell leukaemia in the rat. Eur Cytokine Netw, 8( 1), 45-9. eScholarID:1d28595
Roe S.Y., Cooper A.L., Morris I.D., Rothwell N.J. (1997). Involvement of prostaglandins in cachexia induced by T-cell leukemia in the rat. Metabolism: clinical and experimental, 46, 359. eScholarID:1c547
Roe S, Cooper A, Morris I, Rothwell NJ. (1997). Involvement of prostaglandins in cachexia induced by T-cell leukemia in the rat. Metabolism, 46( 4), 359-65. eScholarID:1d28576
Miller A.J., Luheshi G.N., Rothwell N.J., Hopkins S.J. (1997). Local cytokine induction by LPS in the rat air pouch and its relationship to the febrile response. Am.J.Physiol, 272, R857. eScholarID:1c530
Miller A, Luheshi G, Rothwell NJ, Hopkins S. (1997). Local cytokine induction by LPS in the rat air pouch and its relationship to the febrile response. Am J Physiol, 272( 3 Pt 2), R857-61. eScholarID:1d28941
Benkovic S.A., McGowan E.M., Rothwell N.J., Hutton M., Morgan D.G., Gordon M.N. (1997). Regional and cellular localization of presenilin-2 RNA in rat and human brain. Exp.Neurol, 145, 555. eScholarID:1c439
Rothwell N.J. (1997). Sixteenth Gaddum Memorial Lecture December 1996. Neuroimmune interactions: the role of cytokines. British journal of pharmacology, 121, 841. eScholarID:1c657
Rothwell NJ. (1997). Sixteenth Gaddum Memorial Lecture December 1996. Neuroimmune interactions: the role of cytokines. Br J Pharmacol, 121( 5), 841-7. eScholarID:1d28940
Rothwell NJ, Allan S, Toulmond S. (1997). The role of interleukin 1 in acute neurodegeneration and stroke: pathophysiological and therapeutic implications. J Clin Invest, 100( 11), 2648-52. eScholarID:1d28574
Roe S.Y., Rothwell N.J. (1997). Whole body metabolic responses to brain trauma in the rat. J.Neurotrauma, 14, 399. eScholarID:1c548
Roe S, Rothwell NJ. (1997). Whole body metabolic responses to brain trauma in the rat. J Neurotrauma, 14( 6), 399-408. eScholarID:1d28950
1996
Loddick S.A., MacKenzie A., Rothwell N.J. (1996). An ICE inhibitor, z-VAD-DCB attenuates ischaemic brain damage in the rat. Neuroreport, 7, 1465. eScholarID:1c514
Loddick S, MacKenzie A, Rothwell NJ. (1996). An ICE inhibitor, z-VAD-DCB attenuates ischaemic brain damage in the rat. Neuroreport, 7( 9), 1465-8. eScholarID:1d29192
Rothwell NJ, Luheshi G. (1996). Brain TNF: damage limitation or damaged reputation? Nat Med, 2( 7), 746-7. eScholarID:1d28452
Rothwell N.J., Luheshi G., Toulmond S. (1996). Cytokines and their receptors in the central nervous system: physiology, pharmacology, and pathology. Pharmacol.Ther, 69, 85. eScholarID:1c653
Rothwell NJ, Luheshi G, Toulmond S. (1996). Cytokines and their receptors in the central nervous system: physiology, pharmacology, and pathology. Pharmacol Ther, 69( 2), 85-95. eScholarID:1d29019
Luheshi G., Miller A.J., Brouwer S., Dascombe M.J., Rothwell N.J., Hopkins S.J. (1996). Interleukin-1 receptor antagonist inhibits endotoxin fever and systemic interleukin-6 induction in the rat. Am.J.Physiol, 270, E91. eScholarID:1c520
Luheshi G, Miller A, Brouwer S, Dascombe M, Rothwell NJ, Hopkins S. (1996). Interleukin-1 receptor antagonist inhibits endotoxin fever and systemic interleukin-6 induction in the rat. Am J Physiol, 270( 1 Pt 1), E91-5. eScholarID:1d28596
Sudlow A.W., Carey F., Forder R., Rothwell N.J. (1996). Lipocortin-1 inhibits CRH stimulation of plasma ACTH and IL-1 beta-stimulated hypothalamic CRH release in rats. Am.J.Physiol, 270, R54. eScholarID:1c679
Sudlow A, Carey F, Forder R, Rothwell NJ. (1996). Lipocortin-1 inhibits CRH stimulation of plasma ACTH and IL-1 beta-stimulated hypothalamic CRH release in rats. Am J Physiol, 270( 1 Pt 2), R54-60. eScholarID:1d28577
Roe S., Cooper A.L., Morris I.D., Rothwell N.J. (1996). Mechanisms of cachexia induced by T-cell leukemia in the rat. Metabolism: clinical and experimental, 45, 645. eScholarID:1c545
Roe S, Cooper A, Morris I, Rothwell NJ. (1996). Mechanisms of cachexia induced by T-cell leukemia in the rat. Metabolism, 45( 5), 645-51. eScholarID:1d29018
Loddick S.A., Rothwell N.J. (1996). Neuroprotective effects of human recombinant interleukin-1 receptor antagonist in focal cerebral ischaemia in the rat. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 16, 932. eScholarID:1c515
Loddick S, Rothwell NJ. (1996). Neuroprotective effects of human recombinant interleukin-1 receptor antagonist in focal cerebral ischaemia in the rat. J Cereb Blood Flow Metab, 16( 5), 932-40. eScholarID:1d28451
Stefferl A., Hopkins S.J., Rothwell N.J., Luheshi G.N. (1996). The role of TNF-alpha in fever: opposing actions of human and murine TNF-alpha and interactions with IL-beta in the rat. British journal of pharmacology, 118, 1919. eScholarID:1c664
Stefferl A, Hopkins S, Rothwell NJ, Luheshi G. (1996). The role of TNF-alpha in fever: opposing actions of human and murine TNF-alpha and interactions with IL-beta in the rat. Br J Pharmacol, 118( 8), 1919-24. eScholarID:1d29191
Sudlow A.W., Carey F., Forder R., Rothwell N.J. (1996). The role of lipocortin-1 in dexamethasone-induced suppression of PGE2 and TNF alpha release from human peripheral blood mononuclear cells. British journal of pharmacology, 117, 1449. eScholarID:1c680
Sudlow A, Carey F, Forder R, Rothwell NJ. (1996). The role of lipocortin-1 in dexamethasone-induced suppression of PGE2 and TNF alpha release from human peripheral blood mononuclear cells. Br J Pharmacol, 117( 7), 1449-56. eScholarID:1d28942
1995
Rothwell N.J., Hopkins S.J. (1995). Cytokines and the nervous system II: Actions and mechanisms of action. Trends in neurosciences, 18, 130. eScholarID:1c650
Rothwell NJ, Hopkins S. (1995). Cytokines and the nervous system II: Actions and mechanisms of action. Trends Neurosci, 18( 3), 130-6. eScholarID:1d28952
Hopkins S.J., Rothwell N.J. (1995). Cytokines and the nervous system. I: Expression and recognition. Trends in neurosciences, 18, 83. eScholarID:1c497
Hopkins S, Rothwell NJ. (1995). Cytokines and the nervous system. I: Expression and recognition. Trends Neurosci, 18( 2), 83-8. eScholarID:1d29020
Rothwell N.J., Strijbos P.J. (1995). Cytokines in neurodegeneration and repair. Int.J.Dev.Neurosci, 13, 179. eScholarID:1c651
Rothwell NJ, Strijbos P. (1995). Cytokines in neurodegeneration and repair. Int J Dev Neurosci, 13( 3-4), 179-85. eScholarID:1d28578
Wong M.L., Loddick S.A., Bongiorno P.B., Gold P.W., Rothwell N.J., Licinio J. (1995). Focal cerebral ischemia induces CRH mRNA in rat cerebral cortex and amygdala. Neuroreport, 6, 1785. eScholarID:1c684
Strijbos P.J., Rothwell N.J. (1995). Interleukin-1 beta attenuates excitatory amino acid-induced neurodegeneration in vitro: involvement of nerve growth factor. Journal of Neuroscience, 15, 3468. eScholarID:1c675
Strijbos P.J., Zamani M.R., Rothwell N.J., Arbuthnott G., Harkiss G. (1995). Neurotoxic mechanisms of transactivating protein Tat of Maedi-Visna virus. Neuroscience letters, 197, 215. eScholarID:1c676
1994
Cartana J., Segues T., Yebras M., Rothwell N.J., Stock M.J. (1994). Anabolic effects of clenbuterol after long-term treatment and withdrawal in t the rat. Metabolism: clinical and experimental, 43, 1086. eScholarID:1c455
Turnbull A.V., Dow R.C., Hopkins S.J., White A., Fink G., Rothwell N.J. (1994). Mechanisms of activation of the pituitary-adrenal axis by tissue injury in the rat. Psychoneuroendocrinology, 19, 165. eScholarID:1c682
Rothwell N.J., Luheshi G. (1994). Pharmacology of interleukin-1 actions in the brain. Adv.Pharmacol, 25, eScholarID:1c320
Rothwell NJ, Luheshi G. (1994). Pharmacology of interleukin-1 actions in the brain. Adv Pharmacol, 25, 1-20. eScholarID:1d28943
Cooper A.L., Brouwer S., Turnbull A.V., Luheshi G.N., Hopkins S.J., Kunkel S.L., Rothwell N.J. (1994). Tumor necrosis factor-alpha and fever after peripheral inflammation in the rat. Am.J.Physiol, 267, R1431. eScholarID:1c473
Cooper A, Brouwer S, Turnbull A, Luheshi G, Hopkins S, Kunkel S, Rothwell NJ. (1994). Tumor necrosis factor-alpha and fever after peripheral inflammation in the rat. Am J Physiol, 267( 6 Pt 2), R1431-6. eScholarID:1d28597
1993
Busbridge N.J., Dascombe M.J., Rothwell N.J. (1993). Chronic effects of interleukin-1 beta on fever, oxygen consumption and food intake in the rat. Horm.Metab Res, 25, 222. eScholarID:1c453
Busbridge N, Dascombe M, Rothwell NJ. (1993). Chronic effects of interleukin-1 beta on fever, oxygen consumption and food intake in the rat. Horm Metab Res, 25( 4), 222-7. eScholarID:1d28953
Martineau L., Little R.A., Rothwell N.J., Fisher M.I. (1993). Clenbuterol, a beta 2-adrenergic agonist, reverses muscle wasting due to scald injury in the rat. Burns, 19, 26. eScholarID:1c528
Martineau L, Little R, Rothwell NJ, Fisher M. (1993). Clenbuterol, a beta 2-adrenergic agonist, reverses muscle wasting due to scald injury in the rat. Burns, 19( 1), 26-34. eScholarID:1d28580
Rothwell NJ. (1993). Cytokines and thermogenesis. Int J Obes Relat Metab Disord, 17 Suppl 3, S98-101; discussion 115. eScholarID:1d28454
Coelho M.M., Pela I.R., Rothwell N.J. (1993). Dexamethasone inhibits the pyrogenic activity of prostaglandin F2 alpha, but not prostaglandin E2. Eur.J.Pharmacol, 238, 391. eScholarID:1c465
Coelho M, Pelá I, Rothwell NJ. (1993). Dexamethasone inhibits the pyrogenic activity of prostaglandin F2 alpha, but not prostaglandin E2. Eur J Pharmacol, 238(2-3), 391-394. eScholarID:1d29732
Relton J.K., Strijbos P.J., Cooper A.L., Rothwell N.J. (1993). Dietary N-3 fatty acids inhibit ischaemic and excitotoxic brain damage in the rat. Brain Res.Bull, 32, 223. eScholarID:1c544
Relton J, Strijbos P, Cooper A, Rothwell NJ. (1993). Dietary N-3 fatty acids inhibit ischaemic and excitotoxic brain damage in the rat. Brain Res Bull, 32( 3), 223-6. eScholarID:1d28960
Derijk R.H., Strijbos P.J., van Rooijen N., Rothwell N.J., Berkenbosch F. (1993). Fever and thermogenesis in response to bacterial endotoxin involve macrophage-dependent mechanisms in rats. Am.J.Physiol, 265, R1179. eScholarID:1c481
Strijbos P.J., Horan M.A., Carey F., Rothwell N.J. (1993). Impaired febrile responses of aging mice are mediated by endogenous lipocortin-1 (annexin-1). Am.J.Physiol, 265, E289. eScholarID:1c673
Strijbos P, Horan M, Carey F, Rothwell NJ. (1993). Impaired febrile responses of aging mice are mediated by endogenous lipocortin-1 (annexin-1). Am J Physiol, 265( 2 Pt 1), E289-97. eScholarID:1d29731
Luheshi G., Hopkins S.J., LeFeuvre R.A., Dascombe M.J., Ghiara P., Rothwell N.J. (1993). Importance of brain IL-1 type II receptors in fever and thermogenesis in the rat. Am.J.Physiol, 265, E585. eScholarID:1c519
Luheshi G, Hopkins S, Lefeuvre R, Dascombe M, Ghiara P, Rothwell NJ. (1993). Importance of brain IL-1 type II receptors in fever and thermogenesis in the rat. Am J Physiol, 265( 4 Pt 1), E585-91. eScholarID:1d29199
Cooper A.L., Rothwell N.J. (1993). Inhibition of the thermogenic and pyrogenic responses to interleukin-1 beta in the rat by dietary N-3 fatty acid supplementation. Prostaglandins Leukot.Essent.Fatty Acids, 49, 615. eScholarID:1c472
Cooper A, Rothwell NJ. (1993). Inhibition of the thermogenic and pyrogenic responses to interleukin-1 beta in the rat by dietary N-3 fatty acid supplementation. Prostaglandins Leukot Essent Fatty Acids, 49( 2), 615-26. eScholarID:1d28598
Rothwell N.J., Relton J.K. (1993). Involvement of cytokines in acute neurodegeneration in the CNS. Neurosci.Biobehav.Rev, 17, 217. eScholarID:1c647
Rothwell NJ, Relton J. (1993). Involvement of cytokines in acute neurodegeneration in the CNS. Neurosci Biobehav Rev, 17( 2), 217-27. eScholarID:1d28581
Rothwell N.J., Relton J.K. (1993). Involvement of interleukin-1 and lipocortin-1 in ischaemic brain damage. Cerebrovasc.Brain Metab Rev, 5, 178. eScholarID:1c648
Rothwell NJ, Relton J. (1993). Involvement of interleukin-1 and lipocortin-1 in ischaemic brain damage. Cerebrovasc Brain Metab Rev, 5( 3), 178-98. eScholarID:1d29733
Turnbull A.V., Kirkman E., Rothwell N.J., Little R.A. (1993). The neuropeptide CRF is involved in the modulation of the baroreflex during hindlimb ischaemia in the anaesthetized rat. Journal of physiology, Paris, 468, 529. eScholarID:1c681
Turnbull A, Kirkman E, Rothwell NJ, Little R. (1993). The neuropeptide CRF is involved in the modulation of the baroreflex during hindlimb ischaemia in the anaesthetized rat. J Physiol, 468, 529-41. eScholarID:1d28944
1992
Royston M.C., Rothwell N.J., Roberts G.W. (1992). Alzheimer"s disease: pathology to potential treatments? Trends Pharmacol.Sci, 13, 131. eScholarID:1c662
Choo J.J., Horan M.A., Little R.A., Rothwell N.J. (1992). Anabolic effects of clenbuterol on skeletal muscle are mediated by beta 2-adrenoceptor activation. Am.J.Physiol, 263, E50. eScholarID:1c464
Choo J, Horan M, Little R, Rothwell NJ. (1992). Anabolic effects of clenbuterol on skeletal muscle are mediated by beta 2-adrenoceptor activation. Am J Physiol, 263( 1 Pt 1), E50-6. eScholarID:1d29200
Kent S., Bluthe R.M., Dantzer R., Hardwick A.J., Kelley K.W., Rothwell N.J., Vannice J.L. (1992). Different receptor mechanisms mediate the pyrogenic and behavioral effects of interleukin 1. Proc.Natl.Acad.Sci.U.S.A, 89, 9117. eScholarID:1c506
Strijbos P.J., Hardwick A.J., Relton J.K., Carey F., Rothwell N.J. (1992). Inhibition of central actions of cytokines on fever and thermogenesis by lipocortin-1 involves CRF. Am.J.Physiol, 263, E632. eScholarID:1c672
Strijbos P, Hardwick A, Relton J, Carey F, Rothwell NJ. (1992). Inhibition of central actions of cytokines on fever and thermogenesis by lipocortin-1 involves CRF. Am J Physiol, 263( 4 Pt 1), E632-6. eScholarID:1d28599
Relton J.K., Rothwell N.J. (1992). Interleukin-1 receptor antagonist inhibits ischaemic and excitotoxic neuronal damage in the rat. Brain research bulletin, 29, 243. eScholarID:1c543
Relton J, Rothwell NJ. (1992). Interleukin-1 receptor antagonist inhibits ischaemic and excitotoxic neuronal damage in the rat. Brain Res Bull, 29( 2), 243-6. eScholarID:1d29735
Black M.D., Carey F., Crossman A.R., Relton J.K., Rothwell N.J. (1992). Lipocortin-1 inhibits NMDA receptor-mediated neuronal damage in the striatum of the rat. Brain research, 585, 135. eScholarID:1c441
Black M, Carey F, Crossman AA.R, Relton J, Rothwell NJ. (1992). Lipocortin-1 inhibits NMDA receptor-mediated neuronal damage in the striatum of the rat. Brain Res, 585( 1-2), 135-40. eScholarID:1d28455
Cooper A.L., Horan M.A., Little R.A., Rothwell N.J. (1992). Metabolic and febrile responses to typhoid vaccine in humans: effect of beta-adrenergic blockade. J.Appl.Physiol, 72, 2322. eScholarID:1c471
Cooper A, Horan M, Little R, Rothwell NJ. (1992). Metabolic and febrile responses to typhoid vaccine in humans: effect of beta-adrenergic blockade. J Appl Physiol, 72( 6), 2322-8. eScholarID:1d28456
Martineau L., Horan M.A., Rothwell N.J., Little R.A. (1992). Muscling in on salbutamol. Lancet, 340, 1094. eScholarID:1c526
Martineau L., Horan M.A., Rothwell N.J., Little R.A. (1992). Salbutamol, a beta 2-adrenoceptor agonist, increases skeletal muscle strength in young men. Clin.Sci.(Lond), 83, 615. eScholarID:1c527
Martineau L, Horan M, Rothwell NJ, Little R. (1992). Salbutamol, a beta 2-adrenoceptor agonist, increases skeletal muscle strength in young men. Clin Sci (Lond), 83( 5), 615-21. eScholarID:1d29734
Rothwell N.J., Le Feuvre R.A. (1992). Thermogenesis, brown adipose tissue and dexfenfluramine in animal studies. Int.J.Obes.Relat Metab Disord, 16 Suppl 3, S67. eScholarID:1c645
Rothwell NJ, Le Feuvre R. (1992). Thermogenesis, brown adipose tissue and dexfenfluramine in animal studies. Int J Obes Relat Metab Disord, 16 Suppl 3, S67-71. eScholarID:1d28945
Serra F., LeFeuvre R.A., Slater D., Palou A., Rothwell N.J. (1992). Thermogenic actions of tryptophan in the rat are mediated independently of 5-HT. Brain research, 578, 327. eScholarID:1c663
1991
Rothwell N.J., Little R.A., Rose J.G. (1991). Brown adipose tissue activity and oxygen consumption after scald injury in the rat. Circ.Shock, 33, 33. eScholarID:1c638
Rothwell NJ, Little R, Rose J. (1991). Brown adipose tissue activity and oxygen consumption after scald injury in the rat. Circ Shock, 33( 1), 33-6. eScholarID:1d29029
Rothwell N.J., Hardwick A., LeFeuvre R.A., Crosby S.R., White A. (1991). Central actions of CRF on thermogenesis are mediated by pro-opiomelanocortin products. Brain research, 541, 89. eScholarID:1c639
Choo J.J., Emery P.W., Rothwell N.J. (1991). Dose-dependent effects of an anabolic steroid, nandrolone phenylpropionate (Durabolin), on body composition and muscle protein metabolism in female rats. Ann.Nutr.Metab, 35, 141. eScholarID:1c463
Le Feuvre R.A., Woods A.J., Stock M.J., Rothwell N.J. (1991). Effects of central injection of glucose on thermogenesis in normal, VMH-lesioned and genetically obese rats. Brain research, 547, 110. eScholarID:1c510
Le Feuvre R, Woods A, Stock M, Rothwell NJ. (1991). Effects of central injection of glucose on thermogenesis in normal, VMH-lesioned and genetically obese rats. Brain Res, 547( 1), 110-4. eScholarID:1d28588
Rothwell N.J. (1991). Functions and mechanisms of interleukin 1 in the brain. Trends Pharmacol.Sci, 12, 430. eScholarID:1c640
Rothwell NJ. (1991). Functions and mechanisms of interleukin 1 in the brain. Trends Pharmacol Sci, 12( 11), 430-6. eScholarID:1d28437
Hopkins S.J., Rothwell N.J. (1991). Further functions of IL-6. Immunol.Today, 12, 170. eScholarID:1c496
Rothwell N.J., Busbridge N.J., LeFeuvre R.A., Hardwick A.J., Gauldie J., Hopkins S.J. (1991). Interleukin-6 is a centrally acting endogenous pyrogen in the rat. Can.J.Physiol Pharmacol, 69, 1465. eScholarID:1c641
Rothwell NJ, Busbridge N, Lefeuvre R, Hardwick A, Gauldie J, Hopkins S. (1991). Interleukin-6 is a centrally acting endogenous pyrogen in the rat. Can J Physiol Pharmacol, 69( 10), 1465-9. eScholarID:1d29023
Le Feuvre R.A., Aisenthal L., Rothwell N.J. (1991). Involvement of corticotrophin releasing factor (CRF) in the thermogenic and anorexic actions of serotonin (5-HT) and related compounds. Brain research, 555, 245. eScholarID:1c511
Le Feuvre R, Aisenthal L, Rothwell NJ. (1991). Involvement of corticotrophin releasing factor (CRF) in the thermogenic and anorexic actions of serotonin (5-HT) and related compounds. Brain Res, 555( 2), 245-50. eScholarID:1d28946
Relton J.K., Strijbos P.J., O"Shaughnessy C.T., Carey F., Forder R.A., Tilders F.J., Rothwell N.J. (1991). Lipocortin-1 is an endogenous inhibitor of ischemic damage in the rat brain. J.Exp.Med, 174, 305. eScholarID:1c542
Relton J, Strijbos P, O'Shaughnessy C, Carey F, Forder R, Tilders F, Rothwell NJ. (1991). Lipocortin-1 is an endogenous inhibitor of ischemic damage in the rat brain. J Exp Med, 174( 2), 305-10. eScholarID:1d28961
Strijbos P.J., Tilders F.J., Carey F., Forder R., Rothwell N.J. (1991). Localization of immunoreactive lipocortin-1 in the brain and pituitary gland of the rat. Effects of adrenalectomy, dexamethasone and colchicine treatment. Brain research, 553, 249. eScholarID:1c671
Strijbos P, Tilders F, Carey F, Forder R, Rothwell NJ. (1991). Localization of immunoreactive lipocortin-1 in the brain and pituitary gland of the rat. Effects of adrenalectomy, dexamethasone and colchicine treatment. Brain Res, 553( 2), 249-60. eScholarID:1d28962
Cooper A.L., Rothwell N.J. (1991). Mechanisms of early and late hypermetabolism and fever after localized tissue injury in rats. Am.J.Physiol, 261, E698. eScholarID:1c470
Cooper A, Rothwell NJ. (1991). Mechanisms of early and late hypermetabolism and fever after localized tissue injury in rats. Am J Physiol, 261( 6 Pt 1), E698-705. eScholarID:1d28600
Rothwell N.J. (1991). The endocrine significance of cytokines. J.Endocrinol, 128, 171. eScholarID:1c642
Rothwell NJ. (1991). The endocrine significance of cytokines. J Endocrinol, 128( 2), 171-3. eScholarID:1d28606
1990
Busbridge N.J., Carnie J.A., Dascombe M.J., Johnston J.A., Rothwell N.J. (1990). Adrenalectomy reverses the impaired pyrogenic responses to interleukin-beta in obese Zucker rats. Int.J.Obes, 14, 809. eScholarID:1c452
Busbridge N, Carnie J, Dascombe M, Johnston J, Rothwell NJ. (1990). Adrenalectomy reverses the impaired pyrogenic responses to interleukin-beta in obese Zucker rats. Int J Obes, 14( 9), 809-14. eScholarID:1d28458
Choo J.J., Horan M.A., Little R.A., Rothwell N.J., Wareham A. (1990). Anabolic beta-2-agonist clenbuterol fails to modify muscle atrophy due to femur fracture. Circ.Shock, 32, 165. eScholarID:1c461
Choo J, Horan M, Little R, Rothwell NJ, Wareham A. (1990). Anabolic beta-2-agonist clenbuterol fails to modify muscle atrophy due to femur fracture. Circ Shock, 32( 2), 165-71. eScholarID:1d29203
Rothwell N.J., Hardwick A.J., Lindley I. (1990). Central actions of interleukin-8 in the rat are independent of prostaglandins. Horm.Metab Res, 22, 595. eScholarID:1c633
Rothwell NJ, Hardwick A, Lindley I. (1990). Central actions of interleukin-8 in the rat are independent of prostaglandins. Horm Metab Res, 22( 11), 595-6. eScholarID:1d29030
Rothwell N.J. (1990). Central activation of thermogenesis by prostaglandins: dependence on CRF. Horm.Metab Res, 22, 616. eScholarID:1c634
Rothwell NJ. (1990). Central activation of thermogenesis by prostaglandins: dependence on CRF. Horm Metab Res, 22( 12), 616-8. eScholarID:1d28947
Rothwell N.J. (1990). Central effects of CRF on metabolism and energy balance. Neurosci.Biobehav.Rev, 14, 263. eScholarID:1c635
Rothwell NJ. (1990). Central effects of CRF on metabolism and energy balance. Neurosci Biobehav Rev, 14( 3), 263-71. eScholarID:1d28607
Arnold J., Choo J.J., Little R.A., Rothwell N.J. (1990). Dopamine beta-hydroxylase inhibition reveals a selective influence of endotoxin on catecholamine content of rat tissues. Circ.Shock, 31, 387. eScholarID:1c437
Arnold J, Choo J, Little R, Rothwell NJ. (1990). Dopamine beta-hydroxylase inhibition reveals a selective influence of endotoxin on catecholamine content of rat tissues. Circ Shock, 31( 4), 387-94. eScholarID:1d29736
Choo J.J., Horan M.A., Little R.A., Rothwell N.J. (1990). Effects of the beta 2-adrenoceptor agonist, clenbuterol, on muscle atrophy due to food deprivation in the rat. Metabolism: clinical and experimental, 39, 647. eScholarID:1c462
Choo J, Horan M, Little R, Rothwell NJ. (1990). Effects of the beta 2-adrenoceptor agonist, clenbuterol, on muscle atrophy due to food deprivation in the rat. Metabolism, 39( 6), 647-50. eScholarID:1d28954
Carey F., Forder R., Edge M.D., Greene A.R., Horan M.A., Strijbos P.J., Rothwell N.J. (1990). Lipocortin 1 fragment modifies pyrogenic actions of cytokines in rats. Am.J.Physiol, 259, R266. eScholarID:1c454
Rothwell N.J. (1990). Mechanisms of the pyrogenic actions of cytokines. Eur.Cytokine Netw, 1, 211. eScholarID:1c636
Rothwell NJ. (1990). Mechanisms of the pyrogenic actions of cytokines. Eur Cytokine Netw, 1( 4), 211-3. eScholarID:1d29202
Rothwell N.J. (1990). Neuroendocrine mechanisms in the thermogenic responses to diet, infection, and trauma. Adv.Exp.Med.Biol, 274, 371. eScholarID:1c637
Rothwell NJ. (1990). Neuroendocrine mechanisms in the thermogenic responses to diet, infection, and trauma. Adv Exp Med Biol, 274, 371-80. eScholarID:1d29737
O"Shaughnessy C.T., Rothwell N.J., Shrewsbury-Gee J. (1990). Sympathetically mediated hypermetabolic response to cerebral ischemia in the rat. Can.J.Physiol Pharmacol, 68, 1334. eScholarID:1c535
O'Shaughnessy C, Rothwell NJ, Shrewsbury-Gee J. (1990). Sympathetically mediated hypermetabolic response to cerebral ischemia in the rat. Can J Physiol Pharmacol, 68( 10), 1334-7. eScholarID:1d28457
1989
Le Feuvre R.A., Rothwell N.J., White A. (1989). A comparison of the thermogenic effects of CRF, sauvagine and urotensin I in the rat. Horm.Metab Res, 21, 525. eScholarID:1c509
Le Feuvre R, Rothwell NJ, White A. (1989). A comparison of the thermogenic effects of CRF, sauvagine and urotensin I in the rat. Horm Metab Res, 21( 9), 525-6. eScholarID:1d29739
Cooper A.L., Fitzgeorge R.B., Baskerville A., Little R.A., Rothwell N.J. (1989). Bacterial infection (Legionella pneumophila) stimulates fever, metabolic rate and brown adipose tissue activity in the guinea pig. Life sciences, 45, 843. eScholarID:1c468
Cooper A, Fitzgeorge R, Baskerville A, Little R, Rothwell NJ. (1989). Bacterial infection (Legionella pneumophila) stimulates fever, metabolic rate and brown adipose tissue activity in the guinea pig. Life Sci, 45( 9), 843-7. eScholarID:1d28609
Rothwell N.J. (1989). CRF is involved in the pyrogenic and thermogenic effects of interleukin 1 beta in the rat. Am.J.Physiol, 256, E111. eScholarID:1c631
Rothwell NJ. (1989). CRF is involved in the pyrogenic and thermogenic effects of interleukin 1 beta in the rat. Am J Physiol, 256( 1 Pt 1), E111-5. eScholarID:1d28460
Busbridge N.J., Dascombe M.J., Tilders F.J., van Oers J.W., Linton E.A., Rothwell N.J. (1989). Central activation of thermogenesis and fever by interleukin-1 beta and interleukin-1 alpha involves different mechanisms. Biochem.Biophys.Res.Commun, 162, 591. eScholarID:1c451
Busbridge N, Dascombe M, Tilders F, van Oers J, Linton E, Rothwell NJ. (1989). Central activation of thermogenesis and fever by interleukin-1 beta and interleukin-1 alpha involves different mechanisms. Biochem Biophys Res Commun, 162( 2), 591-6. eScholarID:1d28608
Rothwell N.J. (1989). Central control of brown adipose tissue. Proc.Nutr.Soc, 48, 197. eScholarID:1c630
Rothwell NJ. (1989). Central control of brown adipose tissue. Proc Nutr Soc, 48( 2), 197-206. eScholarID:1d29740
Horan M.A., Little R.A., Rothwell N.J., Strijbos P.J. (1989). Comparison of the effects of several endotoxin preparations on body temperature and metabolic rate in the rat. Can.J.Physiol Pharmacol, 67, 1011. eScholarID:1c499
O"Shaughnessy C.T., Rothwell N.J., Shrewsbury-Gee J. (1989). Effects of an analogue of thyrotrophin-releasing hormone, RX77368, on infarct size and cerebral blood flow in focal cerebral ischaemia in the rat. Can.J.Physiol Pharmacol, 67, 1345. eScholarID:1c534
O'Shaughnessy C, Rothwell NJ, Shrewsbury-Gee J. (1989). Effects of an analogue of thyrotrophin-releasing hormone, RX77368, on infarct size and cerebral blood flow in focal cerebral ischaemia in the rat. Can J Physiol Pharmacol, 67( 10), 1345-50. eScholarID:1d28964
Cooper A.L., Dascombe M.J., Rothwell N.J., Vale M.J. (1989). Effects of malaria on O2 consumption and brown adipose tissue activity in mice. J.Appl.Physiol, 67, 1020. eScholarID:1c469
Cooper A, Dascombe M, Rothwell NJ, Vale M. (1989). Effects of malaria on O2 consumption and brown adipose tissue activity in mice. J Appl Physiol, 67( 3), 1020-3. eScholarID:1d28591
McCarthy H.D., O"Shaughnessy C.T., Rothwell N.J. (1989). Endogenous mediators of cerebral ischaemia-induced hypermetabolism in the rat. British journal of pharmacology, 98 Suppl, 838P. eScholarID:1c529
McCarthy H, O'Shaughnessy C, Rothwell NJ. (1989). Endogenous mediators of cerebral ischaemia-induced hypermetabolism in the rat. Br J Pharmacol, 98 Suppl, eScholarID:1d29738
Arnold J., Little R.A., Rothwell N.J. (1989). Energy balance and brown adipose tissue thermogenesis during chronic endotoxemia in rats. J.Appl.Physiol, 66, 1970. eScholarID:1c436
Arnold J, Little R, Rothwell NJ. (1989). Energy balance and brown adipose tissue thermogenesis during chronic endotoxemia in rats. J Appl Physiol, 66( 4), 1970-5. eScholarID:1d29204
Dascombe M.J., Hardwick A., LeFeuvre R.A., Rothwell N.J. (1989). Impaired effects of interleukin-1 beta on fever and thermogenesis in genetically obese rats. Int.J.Obes, 13, 367. eScholarID:1c477
Dascombe M, Hardwick A, Lefeuvre R, Rothwell NJ. (1989). Impaired effects of interleukin-1 beta on fever and thermogenesis in genetically obese rats. Int J Obes, 13( 3), 367-73. eScholarID:1d28459
Bianchi A., Bruce J., Cooper A.L., Childs C., Kohli M., Morris I.D., Morris-Jones P., Rothwell N.J. (1989). Increased brown adipose tissue activity in children with malignant disease. Horm.Metab Res, 21, 640. eScholarID:1c440
Bianchi A, Bruce J, Cooper A, Childs C, Kohli M, Morris I, Morris-Jones P, Rothwell NJ. (1989). Increased brown adipose tissue activity in children with malignant disease. Horm Metab Res, 21( 11), 640-1. eScholarID:1d28589
Choo J.J., Horan M.A., Little R.A., Rothwell N.J. (1989). Muscle wasting associated with endotoxemia in the rat: modification by the beta 2-adrenoceptor agonist clenbuterol. Biosci.Rep, 9, 615. eScholarID:1c460
Choo J, Horan M, Little R, Rothwell NJ. (1989). Muscle wasting associated with endotoxemia in the rat: modification by the beta 2-adrenoceptor agonist clenbuterol. Biosci Rep, 9( 5), 615-21. eScholarID:1d28963
Dascombe M.J., Rothwell N.J., Sagay B.O., Stock M.J. (1989). Pyrogenic and thermogenic effects of interleukin 1 beta in the rat. Am.J.Physiol, 256, E7. eScholarID:1c478
Dascombe M, Rothwell NJ, Sagay B, Stock M. (1989). Pyrogenic and thermogenic effects of interleukin 1 beta in the rat. Am J Physiol, 256( 1 Pt 1), E7-11. eScholarID:1d29212
Rothwell N.J., Stock M.J. (1989). Surgical removal of brown fat results in rapid and complete compensation by other depots. Am.J.Physiol, 257, R253. eScholarID:1c632
Hardwick A.J., Linton E.A., Rothwell N.J. (1989). Thermogenic effects of the antiglucocorticoid RU-486 in the rat: involvement of corticotropin-releasing factor and sympathetic activation of brown adipose tissue. Endocrinology, 124, 1684. eScholarID:1c494
Hardwick A, Linton E, Rothwell NJ. (1989). Thermogenic effects of the antiglucocorticoid RU-486 in the rat: involvement of corticotropin-releasing factor and sympathetic activation of brown adipose tissue. Endocrinology, 124( 4), 1684-8. eScholarID:1d28955
1988
Rothwell N.J., Stock M.J. (1988). Brown adipose tissue: does it play a role in the development of obesity? Diabetes Metab Rev, 4, 595. eScholarID:1c623
Rothwell NJ, Stock M. (1988). Brown adipose tissue: does it play a role in the development of obesity? Diabetes Metab Rev, 4( 6), 595-601. eScholarID:1d29031
Rothwell N.J. (1988). Central effects of TNF alpha on thermogenesis and fever in the rat. Biosci.Rep, 8, 345. eScholarID:1c624
Rothwell NJ. (1988). Central effects of TNF alpha on thermogenesis and fever in the rat. Biosci Rep, 8( 4), 345-52. eScholarID:1d28956
Horan M.A., Little R.A., Rothwell N.J., Stock M.J. (1988). Changes in body composition, brown adipose tissue activity and thermogenic capacity in BN/BiRij rats undergoing senescence. Exp.Gerontol, 23, 455. eScholarID:1c498
Horan M, Little R, Rothwell NJ, Stock M. (1988). Changes in body composition, brown adipose tissue activity and thermogenic capacity in BN/BiRij rats undergoing senescence. Exp Gerontol, 23( 6), 455-61. eScholarID:1d28593
Horton R., Rothwell N.J., Stock M.J. (1988). Chronic inhibition of GABA transaminase results in activation of thermogenesis and brown fat in the rat. Gen.Pharmacol, 19, 403. eScholarID:1c500
Holt S., Rothwell N.J., Stock M.J., York D.A. (1988). Effect of hypophysectomy on energy balance and brown fat activity in obese Zucker rats. Am.J.Physiol, 254, E162. eScholarID:1c495
Rothwell N.J., Stock M.J. (1988). Increased body-weight gain and body protein in castrated and adrenalectomized rats treated with clenbuterol. Br.J.Nutr, 60, 355. eScholarID:1c625
Rothwell N.J., Stock M.J. (1988). Influence of adrenalectomy on age-related changes in energy balance, thermogenesis and brown fat activity in the rat. Comp Biochem.Physiol A, 89, 265. eScholarID:1c626
Rothwell NJ, Stock M. (1988). Insulin and thermogenesis. Int J Obes, 12( 2), 93-102. eScholarID:1d28592
Jepson M.M., Millward D.J., Rothwell N.J., Stock M.J. (1988). Involvement of sympathetic nervous system and brown fat in endotoxin-induced fever in rats. Am.J.Physiol, 255, E617. eScholarID:1c505
Horton R.W., LeFeuvre R.A., Rothwell N.J., Stock M.J. (1988). Opposing effects of activation of central GABAA and GABAB receptors on brown fat thermogenesis in the rat. Neuropharmacology, 27, 363. eScholarID:1c501
Rothwell N.J., Stock M.J. (1988). The cafeteria diet as a tool for studies of thermogenesis. J.Nutr, 118, 925. eScholarID:1c628
Rothwell NJ, Stock M. (1988). The cafeteria diet as a tool for studies of thermogenesis. J Nutr, 118( 8), 925-8. eScholarID:1d29032
Rothwell N.J., Stock M.J., Tedstone A.E. (1988). Thermogenic effects of dihydrocodeine in the rat. Can.J.Physiol Pharmacol, 66, 61. eScholarID:1c629
Griffiths E.C., Rothwell N.J., Stock M.J. (1988). Thermogenic effects of thyrotrophin-releasing hormone and its analogues in the rat. Experientia, 44, 40. eScholarID:1c488
Griffiths E, Rothwell NJ, Stock M. (1988). Thermogenic effects of thyrotrophin-releasing hormone and its analogues in the rat. Experientia, 44( 1), 40-2. eScholarID:1d28970
1987
LeFeuvre R.A., Rothwell N.J., Stock M.J. (1987). Activation of brown fat thermogenesis in response to central injection of corticotropin releasing hormone in the rat. Neuropharmacology, 26, 1217. eScholarID:1c512
Coombes R.C., Rothwell N.J., Shah P., Stock M.J. (1987). Changes in thermogenesis and brown fat activity in response to tumour necrosis factor in the rat. Biosci.Rep, 7, 791. eScholarID:1c467
Rothwell N.J., Stock M.J., Sudera D.K. (1987). Changes in tissue blood flow and beta-receptor density of skeletal muscle in rats treated with the beta2-adrenoceptor agonist clenbuterol. British journal of pharmacology, 90, 601. eScholarID:1c615
Rothwell N.J., Stock M.J. (1987). Effect of a selective beta 2-adrenergic agonist (clenbuterol) on energy balance and body composition in normal and protein deficient rats. Biosci.Rep, 7, 933. eScholarID:1c616
Rothwell N.J., Stock M.J. (1987). Effect of diet and fenfluramine on thermogenesis in the rat: possible involvement of serotonergic mechanisms. Int.J.Obes, 11, 319. eScholarID:1c617
Rothwell N.J., Stock M.J. (1987). Effect of environmental temperature on energy balance and thermogenesis in rats fed normal or low protein diets. J.Nutr, 117, 833. eScholarID:1c618
Rothwell N.J., Stock M.J., Tedstone A.E. (1987). Effects of ciglitazone on energy balance, thermogenesis and brown fat activity in the rat. Mol.Cell Endocrinol, 51, 253. eScholarID:1c619
Rothwell N.J., Stock M.J. (1987). Influence of carbohydrate and fat intake on diet-induced thermogenesis and brown fat activity in rats fed low protein diets. J.Nutr, 117, 1721. eScholarID:1c620
Rothwell N.J., Stock M.J. (1987). Influence of clenbuterol on energy balance, thermogenesis and body composition in lean and genetically obese Zucker rats. Int.J.Obes, 11, 641. eScholarID:1c621
Jepson M.M., Cox M., Bates P.C., Rothwell N.J., Stock M.J., Cady E.B., Millward D.J. (1987). Regional blood flow and skeletal muscle energy status in endotoxemic rats. Am.J.Physiol, 252, E581. eScholarID:1c504
Rothwell N.J., Stock M.J. (1987). Stimulation of thermogenesis and brown fat activity in rats fed medium chain triglyceride. Metabolism: clinical and experimental, 36, 128. eScholarID:1c622
1986
Addae J.I., Rothwell N.J., Stock M.J., Stone T.W. (1986). Activation of thermogenesis of brown fat in rats by baclofen. Neuropharmacology, 25, 627. eScholarID:1c313
Rothwell N.J., Stock M.J. (1986). Body weight and brown fat activity in hyperphagic cafeteria-fed female rats and their offspring. Biol.Neonate, 49, 284. eScholarID:1c609
Stock M.J., Rothwell N.J. (1986). Brown adipose tissue and the response to overfeeding. Biochem.Soc.Trans, 14, 239. eScholarID:1c669
Rothwell N.J., Stock M.J. (1986). Energy balance and brown fat activity in adrenalectomized male, female, and castrated male rats. Metabolism: clinical and experimental, 35, 657. eScholarID:1c610
Rothwell N.J., Stock M.J. (1986). Influence of environmental temperature on energy balance, diet-induced thermogenesis and brown fat activity in "cafeteria"-fed rats. Br.J.Nutr, 56, 123. eScholarID:1c611
Rothwell N.J., Stock M.J. (1986). Spontaneous and experimental variations in body weight, food intake and metabolic rate in captive dormice (Glis glis). Comp Biochem.Physiol A, 84, 141. eScholarID:1c612
Stock M.J., Rothwell N.J. (1986). The role of brown fat in diet-induced thermogenesis. Int.J.Vitam.Nutr.Res, 56, 205. eScholarID:1c670
Marchington D., Rothwell N.J., Stock M.J., York D.A. (1986). Thermogenesis and sympathetic activity in BAT of overfed rats after adrenalectomy. Am.J.Physiol, 250, E362. eScholarID:1c525
Rothwell N.J., Stock M.J., Sudera D.K. (1986). Thermogenic responses to adrenoceptor agonists and brown fat adrenoceptors in overfed rats. Eur.J.Pharmacol, 125, 313. eScholarID:1c613
Rothwell N.J., Stock M.J. (1985). Acute and chronic effects of ACTH on thermogenesis and brown adipose tissue in the rat. Comp Biochem.Physiol A, 81, 99. eScholarID:1c598
Rothwell N.J., Addae J.I., Stock M.J., Stone T.W. (1985). Baclofen is a potent activator of brown fat metabolism. J.Pharm.Pharmacol, 37, 926. eScholarID:1c599
Rothwell N.J., Stock M.J., Sudera D.K. (1985). Beta-adrenoreceptors in rat brown adipose tissue: proportions of beta 1- and beta 2-subtypes. Am.J.Physiol, 248, E397. eScholarID:1c600
Rothwell N.J., Stock M.J., Sudera D.K. (1985). Changes in adrenoreceptor density in brown adipose tissue from hyperthyroid rats. Eur.J.Pharmacol, 114, 227. eScholarID:1c601
Andrews P.L., Rothwell N.J., Stock M.J. (1985). Effects of subdiaphragmatic vagotomy on energy balance and thermogenesis in the rat. Journal of physiology, Paris, 362, 1. eScholarID:1c433
Rothwell N.J., Stock M.J., Warwick B.P. (1985). Energy balance and brown fat activity in rats fed cafeteria diets or high-fat, semisynthetic diets at several levels of intake. Metabolism: clinical and experimental, 34, 474. eScholarID:1c602
Stock M.J., Rothwell N.J. (1985). Factors influencing brown fat and the capacity for diet-induced thermogenesis. Int.J.Obes, 9 Suppl 2, 9. eScholarID:1c668
Rothwell N.J., Saville M.E., Stock M.J. (1985). Hormonal and metabolic responses to fasting and refeeding. Int.J.Obes, 9 Suppl 2, 49. eScholarID:1c603
Andrews P.L., Rothwell N.J., Stock M.J. (1985). Influence of subdiaphragmatic vagotomy and brown fat sympathectomy on thermogenesis in rats. Am.J.Physiol, 249, E239. eScholarID:1c434
Rothwell N.J., Stock M.J., Warwick B.P. (1985). Involvement of insulin in the acute thermogenic responses to food and nonmetabolizable substances. Metabolism: clinical and experimental, 34, 43. eScholarID:1c604
Rothwell N.J., Stock M.J. (1985). Is diet-induced thermogenesis an experimental artefact? Br.J.Nutr, 53, 191. eScholarID:1c605
Rothwell N.J., Stock M.J. (1985). Modification of body composition by clenbuterol in normal and dystrophic (mdx) mice. Biosci.Rep, 5, 755. eScholarID:1c606
Rothwell N.J., Stock M.J. (1985). Thermogenesis and BAT activity in hypophysectomized rats with and without corticotropin replacement. Am.J.Physiol, 249, E333. eScholarID:1c607
Rothwell N.J., Stock M.J. (1985). Thermogenic capacity and brown adipose tissue activity in the common marmoset. Comp Biochem.Physiol A, 81, 683. eScholarID:1c608
1984
Bryant K.R., Rothwell N.J., Stock M.J. (1984). Acute influences on the two GDP-binding sites in brown-adipose-tissue mitochondria. Biosci.Rep, 4, 523. eScholarID:1c449
Rothwell N.J., Saville M.E., Stock M.J. (1984). Brown fat activity in fasted and refed rats. Biosci.Rep, 4, 351. eScholarID:1c589
Emery P.W., Rothwell N.J., Stock M.J., Winter P.D. (1984). Chronic effects of beta 2-adrenergic agonists on body composition and protein synthesis in the rat. Biosci.Rep, 4, 83. eScholarID:1c484
Jamieson L., Stribling D., Rothwell N.J., Stock M.J. (1984). Effect of noradrenaline on oxygen consumption and tissue blood flow in young pigs. Can.J.Physiol Pharmacol, 62, 136. eScholarID:1c503
Rothwell N.J., Stock M.J., York D.A. (1984). Effects of adrenalectomy on energy balance, diet-induced thermogenesis and brown adipose tissue in adult cafeteria-fed rats. Comp Biochem.Physiol A, 78, 565. eScholarID:1c590
Rothwell N.J., Stock M.J. (1984). Effects of denervating brown adipose tissue on the responses to cold, hyperphagia and noradrenaline treatment in the rat. Journal of physiology, Paris, 355, 457. eScholarID:1c591
Rothwell N.J., Stock M.J., Wyllie M.G. (1984). Effects of histamine antagonists on noradrenaline-stimulated blood flow and oxygen consumption of brown adipose tissue in the rat. Pflugers Archiv : European journal of physiology, 402, 325. eScholarID:1c592
Rothwell N.J., Stock M.J. (1984). Energy balance, thermogenesis and brown adipose tissue activity in tube-fed rats. J.Nutr, 114, 1965. eScholarID:1c593
Rothwell N.J., Stock M.J. (1984). Influence of alcohol and sucrose consumption on energy balance and brown fat activity in the rat. Metabolism: clinical and experimental, 33, 768. eScholarID:1c594
Bryant K.R., Rothwell N.J., Stock M.J. (1984). Influence of sodium intake on thermogenesis and brown adipose tissue in the rat. Int.J.Obes, 8, 221. eScholarID:1c450
Rothwell N.J., Stock M.J. (1984). Sympathetic and adrenocorticoid influences on diet-induced thermogenesis and brown fat activity in the rat. Comp Biochem.Physiol A, 79, 575. eScholarID:1c595
Rothwell N.J., Stock M.J. (1984). The development of obesity in animals: the role of dietary factors. Clin.Endocrinol.Metab, 13, 437. eScholarID:1c596
Wyllie M.G., Fletcher A., Rothwell N.J., Stock M.J. (1984). Thermogenic properties of ciclazindol and mazindol in rodents. Int.J.Obes, 8 Suppl 1, 85. eScholarID:1c685
Rothwell N.J., Stock M.J. (1984). Tissue blood flow in control and cold-adapted hyperthyroid rats. Can.J.Physiol Pharmacol, 62, 928. eScholarID:1c597
1983
Rothwell N.J., Stock M.J. (1983). Acute effects of fat and carbohydrate on metabolic rate in normal, cold-acclimated and lean and obese (fa/fa) Zucker rats. Metabolism: clinical and experimental, 32, 371. eScholarID:1c577
Rothwell N.J., Stock M.J., Thexton A.J. (1983). Decerebration activates thermogenesis in the rat. Journal of physiology, Paris, 342, 15. eScholarID:1c578
Rothwell N.J., Stock M.J., Warwick B.P., Winter P.D. (1983). Diurnal variations in circulating hormone levels and brown adipose tissue activity in "cafeteria"-fed rats. Comp Biochem.Physiol A, 75, 461. eScholarID:1c580
Rothwell N.J., Stock M.J. (1983). Effects of age on diet-induced thermogenesis and brown adipose tissue metabolism in the rat. Int.J.Obes, 7, 583. eScholarID:1c581
Marchington D., Rothwell N.J., Stock M.J., York D.A. (1983). Energy balance, diet-induced thermogenesis and brown adipose tissue in lean and obese (fa/fa) Zucker rats after adrenalectomy. J.Nutr, 113, 1395. eScholarID:1c524
Bryant K.R., Rothwell N.J., Stock M.J., Stribling D. (1983). Identification of two mitochondrial GDP-binding sites in rat brown adipose tissue. Biosci.Rep, 3, 589. eScholarID:1c447
Rothwell N.J., Stock M.J., Wyllie M.G. (1983). Influence of chronic administration of ciclazindol on energy balance and brown adipose tissue in adult "cafeteria"-fed rats. J.Auton.Pharmacol, 3, 73. eScholarID:1c582
Rothwell N.J., Saville M.E., Stock M.J., Wyllie M.G. (1983). Influence of thyroid hormone on diet-induced thermogenesis in the rat. Horm.Metab Res, 15, 394. eScholarID:1c319
Rothwell N.J., Stock M.J. (1983). Luxuskonsumption, diet-induced thermogenesis and brown fat: the case in favour. Clin.Sci.(Lond), 64, 19. eScholarID:1c583
Rothwell N.J., Stock M.J., Tyzbir R.S. (1983). Mechanisms of thermogenesis induced by low protein diets. Metabolism: clinical and experimental, 32, 257. eScholarID:1c584
Rothwell N.J., Saville M.E., Stock M.J. (1983). Metabolic responses to fasting and refeeding in lean and genetically obese rats. Am.J.Physiol, 244, R615. eScholarID:1c585
Everard D.M., Rothwell N.J., Stock M.J., Wilson C.A. (1983). Physical changes associated with the onset of precocious puberty in rats after treatment with PMSG. J.Reprod.Fertil, 69, 201. eScholarID:1c485
Emery P.W., Rothwell N.J., Stock M.J. (1983). Protein synthesis in liver, skeletal muscle, and brown adipose tissue of rats fed a protein-deficient diet. Biosci.Rep, 3, 569. eScholarID:1c483
Rothwell N.J., Stock M.J., Trayhurn P. (1983). Reduced lipogenesis in cafeteria-fed rats exhibiting diet-induced thermogenesis. Biosci.Rep, 3, 217. eScholarID:1c586
Stock M.J., Rothwell N.J. (1983). Role of brown adipose tissue thermogenesis in overfeeding: a review. J.R.Soc.Med, 76, 71. eScholarID:1c667
Rothwell N.J., Saville M.E., Stock M.J. (1983). Role of insulin in thermogenic responses to refeeding in 3-day-fasted rats. Am.J.Physiol, 245, E160. eScholarID:1c587
Rothwell N.J., Stock M.J., Warwick B.P. (1983). The effect of high fat and high carbohydrate cafeteria diets on diet-induced thermogenesis in the rat. Int.J.Obes, 7, 263. eScholarID:1c588
1982
Rothwell N.J., Saville M.E., Stock M.J., Wyllie M.G. (1982). Catecholamine and thyroid hormone influence on brown fat Na+, K+-ATPase activity and thermogenesis in the rat. Horm.Metab Res, 14, 261. eScholarID:1c565
Rothwell N.J., Stephens D.N., Stock M.J. (1982). Changes in metabolic rate and brown adipose tissue composition during nutritional rehabilitation of postnatally undernourished rats. Biol.Neonate, 42, 93. eScholarID:1c566
Rothwell N.J., Stock M.J., Wyllie M.G. (1982). Dopaminergic mechanisms in diet-induced thermogenesis and brown adipose tissue metabolism. Eur.J.Pharmacol, 77, 45. eScholarID:1c568
Rothwell N.J., Stock M.J. (1982). Effect of chronic food restriction on energy balance, thermogenic capacity, and brown-adipose-tissue activity in the rat. Biosci.Rep, 2, 543. eScholarID:1c569
Young J.B., Saville E., Rothwell N.J., Stock M.J., Landsberg L. (1982). Effect of diet and cold exposure on norepinephrine turnover in brown adipose tissue of the rat. J.Clin.Invest, 69, 1061. eScholarID:1c686
Brooks S.L., Rothwell N.J., Stock M.J. (1982). Effects of diet and acute noradrenaline treatment on brown adipose tissue development and mitochondrial purine-nucleotide binding. Q.J.Exp.Physiol, 67, 259. eScholarID:1c445
Rothwell N.J., Stock M.J. (1982). Effects of early overnutrition and undernutrition in rats on the metabolic responses to overnutrition in later life. J.Nutr, 112, 426. eScholarID:1c570
Rothwell N.J., Saville M.E., Stock M.J. (1982). Effects of feeding a "cafeteria" diet on energy balance and diet-induced thermogenesis in four strains of rat. J.Nutr, 112, 1515. eScholarID:1c571
Rothwell N.J., Stock M.J. (1982). Effects of feeding a palatable "cafeteria" diet on energy balance in young and adult lean (+/?) Zucker rats. Br.J.Nutr, 47, 461. eScholarID:1c572
Rothwell N.J., Stock M.J., Tyzbir R.S. (1982). Energy balance and mitochondrial function in liver and brown fat of rats fed "cafeteria" diets of varying protein content. J.Nutr, 112, 1663. eScholarID:1c573
Rothwell N.J., Stock M.J. (1982). Energy expenditure of "cafeteria"-fed rats determined from measurements of energy balance and indirect calorimetry. Journal of physiology, Paris, 328, 371. eScholarID:1c574
Stock M.J., Rothwell N.J. (1982). Evidence for diet-induced thermogenesis in hyperphagic cafeteria-fed rats. Proc.Nutr.Soc, 41, 133. eScholarID:1c666
Rothwell N.J., Saville M.E., Stock M.J. (1982). Factors influencing the acute effect of food on oxygen consumption in the rat. Int.J.Obes, 6, 53. eScholarID:1c575
Rothwell N.J., Saville M.E., Stock M.J. (1982). Sympathetic and thyroid influences on metabolic rate in fed, fasted, and refed rats. Am.J.Physiol, 243, R339. eScholarID:1c576
1981
Rothwell N.J., Stock M.J. (1981). A role for insulin in the diet-induced thermogenesis of cafeteria-fed rats. Metabolism: clinical and experimental, 30, 673. eScholarID:1c559
Perkins M.N., Rothwell N.J., Stock M.J., Stone T.W. (1981). Activation of brown adipose tissue thermogenesis by the ventromedial hypothalamus. Nature, 289, 401. eScholarID:1c540
Rothwell N.J., Saville M.E., Stock M.J. (1981). Acute effects of food, 2-deoxy-D-glucose and noradrenaline on metabolic rate and brown adipose tissue in normal and atropinised lean and obese (fa/fa) Zucker rats. Pflugers Archiv : European journal of physiology, 392, 172. eScholarID:1c560
Rothwell N.J., Stock M.J. (1981). Influence of noradrenaline on blood flow to brown adipose tissue in rats exhibiting diet-induced thermogenesis. Pflugers Archiv : European journal of physiology, 389, 237. eScholarID:1c561
Rothwell N.J., Stock M.J., Wyllie M.G. (1981). Na+, K+-ATPase activity and noradrenaline turnover in brown adipose tissue of rats exhibiting diet-induced thermogenesis. Biochem.Pharmacol, 30, 1709. eScholarID:1c562
Rothwell N.J., Stock M.J. (1981). Regulation of energy balance. Annu.Rev.Nutr, 1, 235. eScholarID:1c563
Brooks S.L., Neville A.M., Rothwell N.J., Stock M.J., Wilson S. (1981). Sympathetic activation of brown-adipose-tissue thermogenesis in cachexia. Biosci.Rep, 1, 509. eScholarID:1c444
Stock M.J., Rothwell N.J. (1981). Sympathetic control of brown adipose tissue in the regulation of body weight. Biochem.Soc.Trans, 9, 525. eScholarID:1c665
Rothwell N.J., Stock M.J., Wyllie M.G. (1981). Sympathetic mechanisms in diet-induced thermogenesis: modification by ciclazindol and anorectic drugs. British journal of pharmacology, 74, 539. eScholarID:1c564
1980
Gurr M.I., Mawson R., Rothwell N.J., Stock M.J. (1980). Effects of manipulating dietary protein and energy intake on energy balance and thermogenesis in the pig. J.Nutr, 110, 532. eScholarID:1c493
Brooks S.L., Rothwell N.J., Stock M.J., Goodbody A.E., Trayhurn P. (1980). Increased proton conductance pathway in brown adipose tissue mitochondria of rats exhibiting diet-induced thermogenesis. Nature, 286, 274. eScholarID:1c443
Rothwell N.J., Stock M.J. (1980). Intra-strain differences in the response to overfeeding in the rat. Proc.Nutr.Soc, 39, 20A. eScholarID:1c557
Rothwell N.J., Stock M.J. (1980). Thermogenesis induced by cafeteria feeding in young growing rats. Proc.Nutr.Soc, 39, 45A. eScholarID:1c558
1979
Rothwell N.J., Stock M.J. (1979). A role for brown adipose tissue in diet-induced thermogenesis. Nature, 281, 31. eScholarID:1c552
Rothwell N.J., Stock M.J. (1979). Combined effects of cafeteria and tube-feeding on energy balance in the rat. Proc.Nutr.Soc, 38, 5A. eScholarID:1c553
Rothwell N.J., Stock M.J. (1979). Effects of continuous and discontinuous periods of cafeteria feeding on body weight, resting oxygen consumption and noradrenaline sensitivity in the rat [proceedings]. Journal of physiology, Paris, 291, 59P. eScholarID:1c554
Gurr M.I., Rothwell N.J., Stock M.J. (1979). Effects of tube-feeding iso-energetic amounts of various dietary lipids on energy balance in the rat. Proc.Nutr.Soc, 38, 6A. eScholarID:1c491
Rothwell N.J., Stock M.J. (1979). In vivo determination of body composition by tritium dilution in the rat. Br.J.Nutr, 41, 625. eScholarID:1c555
Rothwell N.J., Stock M.J. (1979). Regulation of energy balance in two models of reversible obesity in the rat. J.Comp Physiol Psychol, 93, 1024. eScholarID:1c556
Gurr M.I., Mawson R., Rothwell N.J., Stock M.J. (1979). Weight maintenance and dietary-induced thermogenesis in the weanling pig [proceedings ]. Journal of physiology, Paris, 291, 60P. eScholarID:1c492
1978
Rothwell N.J., Stock M.J. (1978). A paradox in the control of energy intake in the rat. Nature, 273, 146. eScholarID:1c550
Rothwell N.J., Stock M.J. (1978). Mechanisms of weight gain and loss in reversible obesity in the rat [proceedings]. Journal of physiology, Paris, 276, 60P. eScholarID:1c551
1976
Macdonald I.A., Rothwell N.J., Stock M.J. (1976). Lipolytic and lipogenic activities of adipose tissue during spontaneous fat depletion and repletion [proceedings]. Proc.Nutr.Soc, 35, 129A. eScholarID:1c523
