Skip to navigation | Skip to main content | Skip to footer
Menu Search the University of Manchester siteSearch

Alternatively, use our A–Z index

Dr Philip Day (PhD, FSB, FRSC) - personal details

Contact details

Dr Philip Day

Role: Reader in Quantitative Analytical Genomics - CIGMR/MIB

Tel: +44 (0)161 275 1621

Location:

Genomics Research
Manchester Institute of Biotechnology
The University of Manchester
131 Princess Street
Manchester
M1 7ND

Websites

 

Biography

Philip Day is Reader in Quantitative Analytical Genomics at Manchester University, Director of the Quantitative Molecular Medicine Group and Principle Investigator at the Manchester Institute of Biotechnology, and a member of the Centre for Epidemiology and CIGMR, at the Medical Faculty. He currently is developing synthetic biology and chemical biology approaches to directed evolution of novel proteins and aptamers for biomedical applications. These are used in combination with expertise for building integrated pathogenesis models of CML. Other closely related studies concern the enhanced uptake of anti-cancer drugs through membrane associated transporters, and Philip maintains an academic interest in the biological significance of heterogeneity. 

During 1990 to 1995 he established The Molecular Oncology Prognostic and Research Laboratories at the Birmingham Children’s Hospital, and between 1995 and 1997 he worked on the Human Genome Mapping Project at the Wellcome Trust Centre for Complex Diseases, Oxford, developing high throughput mapping procedures and instrumentation. In 1997 he joined the Department of Biochemistry, Oxford (with Sir E.M. Southern), where he contributed to a very high throughput sequence analysis study. Dr Day has always maintained a deep interest with the production of new and innovative tools for applied quantitative molecular biology, and more recent research programmes have developed interests in miniaturisation for single cell studies. He has a firm belief that units of biologically meaningful data should be presented as molecules per cell. He is developing procedures to enable quantitative data measurements for the implementation of predictive systems biology modeling. This work has produced patent applications related to gene quantification. For over many years he has developed specialist knowledge in the paediatric cancers chronic myeloid leukaemia and neuroblastoma. He is active in several other applied research areas related to transcriptomics and aneuploidy, including interests in integrated miniaturisation for micro total analysis. He has over 110 peer-reviewed papers and presently supervises several PhD degree students. 

Between 1998 and 2002 he founded and headed the Functional Genomics Unit, Childrens’ University Hospital Zurich. In 2002 he moved to the Medical School, University of Manchester and became Director of Operations for CIGMR. He was invited in March 2006 to move his group to the Manchester Institute of Biotechnology (MIB), where he is Principal Investigator, and continues developing applied quantitative measurement in relation to disease progression by working closely with groups in systems biology, analytical instrumentation, miniaturisation and text mining. He was a member of the MIB Council, and established and directed the MRes in Translational Medicine degree programme. Philip serves as an examiner for UK grant bodies, a FP7 EU expert examiner, external examiner for biological sciences degree schemes, University of Cardiff, visiting professor at the Department of Bioengineering, UCI, CA, PGR Tutor, and is an editorial team member for the RSC journal Integrative Biology.

In 2004 and 2008 respectively, he was elected Fellow of the Royal Society of Chemistry and Fellow of the Society of Biology.

Memberships of Committees and Professional Bodies

Fellow of the Royal Society of Chemistry, 2004

Fellow of the Society of Biology, 2008

RSC Editorial Board

Senior Management Team, Centre for Epidemiology

Business Engagement Champion, FMHS

Qualifications

Philip received his BSc from Lancaster University and MSc and PhD degrees from the Wolfson Research laboratories, Birmingham University.

Role

RSC Referee

External Examiner Cardiff University

Visiting Professor UCI

PGR and MBChB Tutor 

Teaching

MBChB Tutor

Module co-ordinator MRes Translational Medicine