Prof Sabine Flitsch - publications

2011

• Voglmeir, Josef; Kaloo, Sara; Laurent, Nicholas; Meloni, Marco M; Bohlmann, Lisa; Wilson, Iain B; Flitsch, Sabine. Biochemical correlation of activity of the alpha-dystroglycan-modifying glycosyltransferase POMGnT1 with mutations in Muscle-Eye-Brain disease. Biochem. J. 2011; 436(2): 447-455. eScholarID:138344 | DOI:10.1042/BJ20101059
• Šardzík, Róbert; Sharma, Ritu; Kaloo, Sara; Voglmeir, Josef; Crocker, Paul R.; Flitsch, Sabine L. Chemoenzymatic synthesis of sialooligosaccharides on arrays for studies of cell surface adhesion. Chem. Commun. 2011; 47(19): 5425-5427. eScholarID:138347 | DOI:10.1039/c1cc10745c
• 126. Robin, Aélig; Köhler, Valentin; Jones, Alison; Ali, Afruja; Kelly, Paul P.; O’Reilly, Elaine; Turner, Nicholas J., Flitsch, Sabine L. Chimeric Self-sufficient P450cam-RhFRed Biocatalysts with Broad Substrate Scope. Beilstein J. Org. Chem. 2011; 7(173): 1494-1498. eScholarID:138355 | DOI:10.3762/bjoc.7.173
• Aletrari, Mina-Olga; McKibbin, Craig; Williams, Helen; Pawar, Vidya; Pietroni, Paola; Lord, J Michael; Flitsch, Sabine L; Whitehead, Roger; Swanton, Eileithyia; High, Stephen; Spooner, Robert A. Eeyarestatin 1 interferes with both retrograde and anterograde intracellular trafficking pathways. PLOS1. 2011; 6(7): e22713. eScholarID:138352 | DOI:10.1371/journal.pone.0022713
• Flitsch, Sabine L. Enzymes in Carbohydrate Chemistry. In-press eScholarID:138357
• Rannes, Julie; Ioannou, Avgousta; Willies, Simon; Grogan, Gideon; Behrens, Carsten; Flitsch, Sabine; Turner, Nicholas. Glycoprotein labelling using engineered variants of galactose oxidase obtained by directed evolution. J. Am. Chem. Soc. 2011; 133(22): 8436-8439. eScholarID:138351 | DOI:10.1021/ja2018477
• 125. Ioannou, Avgousta; Cini, Elena; Timofte, Roxana; Flitsch, Sabine L.; Turner, Nicholas J; Linclau, Bruno. Heavily fluorinated carbohydrates as enzyme substrates: oxidation of tetrafluorinated galactose by galactose oxidase. Chem. Commun. 2011; 47: 11228-11230. eScholarID:138354 | DOI:10.1039/c1cc13956h
• Gotor, Vicente; Flitsch, Sabine. Increasing the diversity of biocatalytic reactions. Current Opinion in Chemical Biology. 2011 April; 15(2): 185-186. eScholarID:123137 | DOI:10.1016/j.cbpa.2011.02.001
• Šardzík, Róbert; Both, Peter; Flitsch, Sabine L. Post-translational modifications – S-linked sugars lost and found. Nature Chem. Biol. 2011; 7(2): 69-70. eScholarID:123136 | DOI:10.1038/nchembio.516
• Alissandratos A, Baudendistel N, Hauer B, Baldenius K, Flitsch S, Halling P. Biocompatible functionalisation of starch. CHEMICAL COMMUNICATIONS. 2011; 47(2): 683-685. eScholarID:113692 | DOI:10.1039/c0cc02908d
• O'Reilly E, Köhler V, Flitsch S, Turner N. Cytochromes P450 as useful biocatalysts: addressing the limitations. Chemical communications (Cambridge, England). 2011 March; 47(9): 2490-501. eScholarID:123134 | PMID:21264369 | DOI:10.1039/c0cc03165h
• Rannes J, Ioannou A, Willies S, Grogan G, Behrens C, Flitsch S, Turner N. Glycoprotein Labeling Using Engineered Variants of Galactose Oxidase Obtained by Directed Evolution. Journal of the American Chemical Society. 2011 May; eScholarID:123131 | PMID:21526835 | DOI:10.1021/ja2018477
• Sardzík R, Sharma R, Kaloo S, Voglmeir J, Crocker P, Flitsch S. Chemoenzymatic synthesis of sialooligosaccharides on arrays for studies of cell surface adhesion. Chemical communications (Cambridge, England). 2011 May; 47(19): 5425-7. eScholarID:123133 | PMID:21468399 | DOI:10.1039/c1cc10745c

2010

• Alissandratos A, Baudendistel N, Flitsch S, Hauer B, Halling P. Lipase-catalysed acylation of starch and determination of the degree of substitution by methanolysis and GC. BMC BIOTECHNOLOGY. 2010 November; 10: eScholarID:113697 | DOI:10.1186/1472-6750-10-82
• Liem K, Noble G, Flitsch S, Webb S. The effect of multivalent binding on the lateral phase separation of adhesive lipids. FARADAY DISCUSSIONS. 2010; 145: 219-233. eScholarID:113691 | DOI:10.1039/b907114h
• Sabbadin F, Hyde R, Robin A, Hilgarth E, Delenne M, Flitsch S, Turner N, Grogan G, Bruce N. LICRED: A Versatile Drop-In Vector for Rapid Generation of Redox-Self-Sufficient Cytochrome P450s. CHEMBIOCHEM. 2010 May; 11(7): 987-994. eScholarID:113694 | DOI:10.1002/cbic.201000104
• Sardzik R, Noble G, Weissenborn M, Martin A, Webb S, Flitsch S. Preparation of aminoethyl glycosides for glycoconjugation. BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY. 2010 July; 6: 699-703. eScholarID:113696 | DOI:10.3762/bjoc.6.81
• Tey L, Loveridge E, Swanwick R, Flitsch S, Allemann R. Highly site-selective stability increases by glycosylation of dihydrofolate reductase. FEBS JOURNAL. 2010 May; 277(9): 2171-2179. eScholarID:113693 | DOI:10.1111/j.1742-4658.2010.07634.x
• Voglmeir J, Sardzik R, Weissenborn M, Flitsch S. Enzymatic Glycosylations on Arrays. OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY. 2010 August; 14(4): 437-444. eScholarID:113695 | DOI:10.1089/omi.2010.0035

2009

• Haddoub, Rose; Rutzler, Michael; Robin, Aelig; Flitsch, Sabine L. Design, synthesis and assaying of potential aquaporin inhibitors. Handbook of Experimental Pharmacology. Berlin, New York, Springer-Verlag.2009: eScholarID:123052
• Noble, Gavin T.; Liem, Kwan Ping; Webb, Simon J.; Flitsch, Sabine L. Effect of multivalent binding on the lateral phase separation of mannosylated and biotinylated lipids. 2009: -. eScholarID:123051
• Bahamontes-Rosa N, Bucher K, Held J, Robin A, Hoffmann W, Flitsch S, Kremsner P, Kun J. In vivo anti-malarial effect of the A-amino alcohol 1t on Plasmodium berghei. PARASITOLOGY RESEARCH. 2009 June; 104(6): 1459-1464. eScholarID:113699 | DOI:10.1007/s00436-009-1348-6
• Cross B, McKibbin C, Callan A, Roboti P, Piacenti M, Rabu C, Wilson C, Whitehead R, Flitsch S, Pool M, High S, Swanton E. Eeyarestatin I inhibits Sec61-mediated protein translocation at the endoplasmic reticulum. JOURNAL OF CELL SCIENCE. 2009 December; 122(23): 4393-4400. eScholarID:113701 | DOI:10.1242/jcs.054494
• Haddoub R, Dauner M, Stefanowicz F, Barattini V, Laurent N, Flitsch S. Enzymatic synthesis of peptides on a solid support. ORGANIC & BIOMOLECULAR CHEMISTRY. 2009; 7(4): 665-670. eScholarID:113698 | DOI:10.1039/b816847d
• Haddoub R, Laurent N, Meloni M, Flitsch S. Straightforward Synthesis of 2-Acetamido-2-deoxy-beta-D-glucopyranosyl Esters under Microwave Conditions. SYNLETT. 2009 December; (20): 3328-3332. eScholarID:113703
• Noble G, Flitsch S, Liem K, Webb S. Assessing the cluster glycoside effect during the binding of concanavalin A to mannosylated artificial lipid rafts. ORGANIC & BIOMOLECULAR CHEMISTRY. 2009; 7(24): 5245-5254. eScholarID:113702 | DOI:10.1039/b910976e
• Robin A, Roberts G, Kisch J, Sabbadin F, Grogan G, Bruce N, Turner N, Flitsch S. Engineering and improvement of the efficiency of a chimeric [P450cam-RhFRed reductase domain] enzyme. CHEMICAL COMMUNICATIONS. 2009; (18): 2478-2480. eScholarID:113700 | DOI:10.1039/b901716j

2008

• Bahamontes-Rosa N, Robin A, Ambrosio A, Messias-Reason I, Beitz E, Flitsch S, Kun J. Monoquaternary ammonium derivatives inhibit growth of protozoan parasites. PARASITOLOGY INTERNATIONAL. 2008 June; 57(2): 132-137. eScholarID:113705 | DOI:10.1016/j.parint.2007.09.006
• Deere J, De Oliveira R, Tomaszewski B, Millar S, Lalaouni A, Solares L, Flitsch S, Halling P. Kinetics of Enzyme Attack on Substrates Covalently Attached to Solid Surfaces: Influence of Spacer Chain Length, Immobilized Substrate Surface Concentration and Surface Charge. Langmuir. 2008 October; 24(20): 11762-11769. eScholarID:1f387 | DOI:10.1021/la801932f
• Karamanska R, Clarke J, Blixt O, MacRae J, Zhang J, Crocker P, Laurent N, Wright A, Flitsch S, Russell D, Field R. Surface plasmon resonance imaging for real-time, label-free analysis of protein interactions with carbohydrate microarrays. GLYCOCONJUGATE JOURNAL. 2008 January; 25(1): 69-74. eScholarID:113704 | DOI:10.1007/s10719-007-9047-y
• Laurent N, Voglmeir J, Wright A, Blackburn J, Pham N, Wong S, Gaskell S, Flitsch S. Enzymatic glycosylation of peptide arrays on gold surfaces. CHEMBIOCHEM. 2008 April; 9(6): 883-887. eScholarID:113706 | DOI:10.1002/cbic.200700692
• Laurent N, Haddoub R, Flitsch S. Enzyme catalysis on solid surfaces. TRENDS IN BIOTECHNOLOGY. 2008 June; 26(6): 328-337. eScholarID:113707 | DOI:10.1016/j.tibtech.2008.03.003
• Laurent N, Voglmeir J, Flitsch S. Glycoarrays - tools for determining protein-carbohydrate interactions and glycoenzyme specificity. Chemical Communications. 2008; (37): 4400-4412. eScholarID:1f231 | DOI:10.1039/b806983m
• Laurent N, Haddoub R, Voglmeir J, Wong S, Gaskell S, Flitsch S. SPOT Synthesis of Peptide Arrays on Self-Assembled Monolayers and their Evaluation as Enzyme Substrates. CHEMBIOCHEM. 2008 November; 9(16): 2592-2596. eScholarID:113711 | DOI:10.1002/cbic.200800481
• Zhi Z, Laurent N, Powel A, Karamanska R, Fais M, Voglmeir J, Wright A, Blackburn J, Crocker P, Russell D, Flitsch S, Field R, Turnbull J. A versatile gold surface approach for fabrication and interrogation of glycoarrays. CHEMBIOCHEM. 2008 July; 9(10): 1568-1575. eScholarID:113708 | DOI:10.1002/cbic.200700788