Bukvic, B., Blekic, M., Simpson, A., Marinho, S., Curtin, J., Hankinson, J., Aberle, N. & Custovic, A (2013). Asthma severity, polymorphisms in 20p13 and their interaction with tobacco smoke exposure. Pediatr Allergy Immunol, 24(1), 10-8. eScholarID:194402 | PMID:23331525 | DOI:10.1111/pai.12019
Curtin, J., Simpson, A., Belgrave, D., Semic-Jusufagic, A., Custovic, A. & Martinez, F (2013). Methylation of IL-2 promoter at birth alters the risk of asthma exacerbations during childhood. Clin Exp Allergy, 43(3), 304-11. eScholarID:194403 | PMID:23414538 | DOI:10.1111/cea.12046
2012
Fernandes BN, Boyle RJ, Gore C, Simpson A, Custovic A. (2012). Food protein-induced enterocolitis syndrome can occur in adults. Journal of Allergy and Clinicla Immunology, eScholarID:178525
Custovic A, Marinho S, Simpson A. (2012). Gene-environment interactions in the development of asthma and atopy. Expert Rev Respir Med, 6(3), 301-308. eScholarID:178530 | DOI:10.1586/ers.12.24
4. Simpson A, Custovic A, Tepper R, Graves P, Stern D, Jones M, Hankinson J, Curtin J, Wu J, Blekic M, Bukvic B, Aberle N, Marinho S, Belgrave D, Morgan W, Martinez F. (2012). Genetic Variation in Vascular Endothelial Growth Factor-A and Lung Function. American Journal of Respiratory and Critical Care Medicine, 185, 1197-1204. eScholarID:178517 | DOI:10.1164/rccm.201112-2191OC
3. Wan YI, Shrine NR, Soler Artigas M, Wain LV, Blakey JD, Moffatt MF, Bush A, Chung KF, Cookson WO, Strachan DP, Heaney L, Al-Momani BA, Mansur AH, Manney S, Thomson NC, Chaudhuri R, Brightling CE, Bafadhel M, Singapuri A, Niven R, Simpson A, Holloway JW, Howarth PH, Hui J, Musk AW, James AL; the Australian Asthma Genetics Consortium, Brown MA, Baltic S, Ferreira MA, Thompson PJ, Tobin MD, Sayers I, Hall IP. (2012). Genome-wide association study to identify genetic determinants of severe asthma. Thorax, 67(9), 762-768. eScholarID:178521 | DOI:10.1136/thoraxjnl-2011-201262
1. Mölter A, Lindley S, de Vocht F, Agius R, Kerry G, Johnson K, Ashmore M, Terry A, i Dimitroulopoulou S, Simpson A. (In-press). Performance of a microenviromental model for estimating personal NO2 exposure in children. eScholarID:149405
Custovic, A., Marinho, S. & Simpson, A (2012). Gene-environment interactions in the development of asthma and atopy. Expert Rev Respir Med, 6(3), 301-8. eScholarID:195023 | PMID:22788944 | DOI:10.1586/ers.12.24
2011
Custovic A, Soderstrom L, Ahlstedt S, SlyPD, Simpson A, Holt PG. (2011). Allergen-specific IgG Antibody Levels Modify The Relationship Between-Allergen Specific IgE And Wheezing In Childhood In Two Population-Based Birth Cohort Studies. J Allergy Clin Immunol, 127(6), 1480-1485. eScholarID:149392
Murray CS, Canoy D, Buchan I, Woodcock A, Simpson A, Custovic A. (2011). Body mass index in young children and allergic disease: gender differences in a longitudinal study. Clin Exp Allergy, 41, 78-85. eScholarID:110783 | DOI:10.1111/j.1365-2222.2010.03598.x
5. Custovic A, Rothers J, Stern D, Simpson A, Woodcock A, Wright AL, Nicolaou NC, Hankinson J, Halonen M, Martinez FD. (2011). Effect of day care attendance on sensitization and atopic wheezing differs by toll-like receptor 2 genotype in 2 population-based birth cohort studies. J Allergy Clin Immunol, 127(2), 390-397. eScholarID:149389 | DOI:10.1016/j.jaci.2010.10.050
Nicolaou N, Murray C, Belgrave D, Poorafshar M, Simpson A, Custovic A. (2011). Quantification of specific IgE to whole peanut extract and peanut components in prediction of peanut allergy. J Allergy Clin Immunol, 127(3), 684-685. eScholarID:149395 | DOI:10.1016/j.jaci.2010.12.012
2. et al. (2011). the EArly Genetics & Lifecourse Epidemiology (EAGLE) Consortium, Weidinger S. Meta-analysis of genome-wide association studies identifies three new risk loci for atopic dermatitis. Nat Genet, doi: 10.1038/ng.1017, eScholarID:149398 | DOI:10.1038/ng.1017
2010
Simpson A, Tan VYF, Winn J, Svensén M, Bishop CM, Heckerman DE, Buchan I, Custovic A. (2010). Beyond Atopy: Multiple Patterns Of Sensitization In Relation To Asthma In A Birth Cohort Study. Am J Respir Crit Care Med, 181(11), 1200-1206. eScholarID:85281 | DOI:10.1164/rccm.200907-1101OC
Nicolaou N, Poorafshar M, Simpson A, Murray C, Kerry G, Härlin A, Winell H, Woodcock A, Ahlstedt S, Custovic A. (2010). Clinical Allergy Versus Tolerance Amongst Peanut Sensitized Children: Prevalence And Differentiation Using Component-Resolved Diagnostics. J Allergy Clin Immunol, 125, 191-197. eScholarID:77209 | DOI:10.1016/j.jaci.2009.10.008
Simpson A, Martinez F. (2010). The Role of LPS in the development of atopy in humans. Clin Exp Allergy, 40, 209-223. eScholarID:77210 | DOI:10.1111/j.1365-2222.2009.03391.x
2009
Patel S, Murray CS, Woodcock A, Simpson A, Custovic A. (2009). Dietary antioxidant intake, allergic sensitisation and allergic diseases in young children. Allergy, 64, 1766-1772. eScholarID:77212 | DOI:10.1111/j.1398-9995.2009.02099.x
Fowler SJ, Langley SJ, Truman NJ, Woodcock A, Simpson A, Custovic A. (2009). Long term effects of allergen sensitisation and exposure in adult asthma: A prospective study. World Allergy Organization Journal, 2(5), 83-90. eScholarID:77214 | DOI:10.1097/WOX.0b013e3181a45f96
Simpson A, Custovic A. (2009). Prevention of allergic sensitization by environmental control. Curr Allergy Asthma Rep, 9(5), 363-369. eScholarID:77211 | DOI:10.1007/s11882-009-0053-y
2008
Henderson J, Granell R, Heron J, Sherriff A, Simpson A, Woodcock AA, Strachan D, Shaheen S, Sterne J. (2008). Associations of wheezing phenotypes in the first 6 years of life with atopy, lung function and airway responsiveness in mid-childhood. Thorax, 63( 11), 974-80. eScholarID:1d32415 | DOI:10.1136/thx.2007.093187
Nicolaou NC, Simpson A, Lowe LA, Murray CS, Woodcock A, Custovic A. (2008). Day-Care Attendance, Position in Sibship and Early Childhood Wheezing: Population-Based Birth Cohort Study. J Allergy Clin Immunol, 122(3), 500-506. eScholarID:66667 | DOI:10.1016/j.jaci.2008.06.033
Smith JA, Drake R, Simpson A, Woodcock A, Pickles A, Custovic A. (2008). Dimensions of Respiratory Symptoms in Pre-school Children: Population-based Birth Cohort Study. Am J Respir Crit Care Med 2008, 177(12), 1358-1363. eScholarID:66661 | DOI:10.1164/rccm.200709-1419OC
Bisgaard H, Simpson A, Palmer CNA, Bønnelykke K, Mclean I, Mukhopadhyay S, Pipper CB, Halkjaer LB, Lipworth B, Hankinson J, Woodcock A, Custovic A. (2008). Gene-Environment Interaction in the Onset of Eczema in Infancy: Filaggrin Loss-of-Function Mutations Enhanced by Neonatal Cat Exposure. PLoS Med, 5(6), e131. eScholarID:66664 | DOI:10.1371/journal.pmed.0050131
2007
Marinho S, Simpson A, Söderström L, Woodcock A, Ahlstedt S, Custovic A. (2007). Quantification of atopy and the probability of rhinitis in preschool children: a population-based birth cohort study. Allergy, 62( 12), eScholarID:1d17521
Marinho S, Simpson A, Lowe L, Kissen P, Murray CS, Custovic A. (2007). Rhinoconjunctivitis in 5-year-old children: a population-based birth cohort study. Allergy, 62(4), 385-393. eScholarID:1d17522 | DOI:10.1111/j.1398-9995.2006.01294.x
Semic-Jusufagic A, Bachert C, Gevaert P, Holtappels G, Lowe L, Woodcock A, Simpson A, Custovic A. (2007). Staphylococcus aureus sensitization and allergic disease in early childhood: population-based birth cohort study. J Allergy Clin Immunol, 119(4), 930-936. eScholarID:1d17523 | DOI:10.1016/j.jaci.2006.12.639
2006
Marinho S, Simpson A, Custovic A. (2006). Allergen avoidance in the secondary and tertiary prevention of allergic diseases: does it work? Prim Care Respir J, 15( 3), 152-8. eScholarID:1d14400
Thomas M, Custovic A, Woodcock A, Morris J, Simpson A, Murray CS. (2006). Atopic wheezing and early life antibiotic exposure: a nested case-control study. Pediatr Allergy Immunol, 17( 3), 184-188. eScholarID:1d14666
Nicolaou N, Yiallouros P, Pipis S, Ioannou P, Simpson A, Custovic A. (2006). Domestic allergen and endotoxin exposure and allergic sensitization in Cyprus. Pediatr Allergy Immunol, 17( 1), 17-21. eScholarID:1d13025
Semic Jusufagic A, Simpson A, Woodcock AA. (2006). Dust mite allergen avoidance as a preventive and therapeutic strategy. Curr Allergy Asthma Rep, 6( 6), 521-6. eScholarID:1d30479
Simpson A, John S, Jury F, Niven R, Niven RR M, Woodcock AA, Ollier WER, Custovic A. (2006). Endotoxin Exposure, CD14 and Allergic Disease: An Interaction between Genes and the Environment. Am J Respir Crit Care Med, 174(4), 386-392. eScholarID:1d13021 | DOI:10.1164/rccm.200509-1380OC
Semic-Jusufagic A, Simpson A, Custovic A. (2006). Environmental exposures, genetic predisposition and allergic diseases: one size never fits all. Allergy, 61( 4), 397-9. eScholarID:1d13024
Keil T, Kulig M, Simpson A, Custovic A, Wickman M, Kull I, Lødrup C, Carlsen K, Smit H, Wijga A, Schmid S, Berg A, Bollrath C, Eller E, Bindslev-Jensen C, Halken S, Høst A, Heinrich J, Porta D, Forastiere F, Brunekreef B, Krämer U, Willich S, Wahn U, Lau S. (2006). European birth cohort studies on asthma and atopic diseases: I. Comparison of study designs -- a GALEN initiative. Allergy, 61(2), 221-228. eScholarID:1d13026 | DOI:10.1111/j.1398-9995.2006.00989.x
Keil, T, Kulig, M, Simpson, A, Custovic, A, Wickman, M, Kull, I, Lødrup Carlsen, K, Carlsen, K, Smit, H, Wijga, A, Schmid, S, Von Berg, A, Bollrath, C, Eller, E, Bindslev-Jensen, C, Halken, S, Høst, A, Heinrich, J, Fantini, M, Brunekreef, B, Krämer, U, Willich, S, Wahn, U, Lau, S. (2006). European birth cohort studies on asthma and atopic diseases: II. Comparison of outcomes and exposures--a GA2LEN initiative. Allergy, 61( 9), 1104-11. eScholarID:1d17524 | DOI:10.1111/j.1398-9995.2006.01167.x
Nicolaou N, Lowe L, Murray CS, Woodcock AA, Simpson A, Custovic A. (2006). Exhaled breath condensate pH and childhood asthma: unselected birth cohort study. Am J Respir Crit Care Med, 174( 3), 254-259. eScholarID:1d14402
Custovic A, Simpson A. (2006). What are we learning from genetic cohort studies? Paediatr Respir Rev, 7 Suppl 1, S90-2. eScholarID:1d14399
2005
Custovic A, Murray CS, Simpson A. (2005). Allergy and infection: understanding their relationship. Allergy, 60 Suppl 79, eScholarID:1d10458
Calam R, Gregg L, Simpson A, Simpson B, Woodcock AA, Custovic A. (2005). Behavior Problems Antecede the Development of Wheeze in Childhood: a Birth Cohort Study. Am J Respir Crit Care Med, 171(4), 323-7. eScholarID:1d9084 | DOI:10.1164/rccm.200406-791OC
Simpson A, Soderstrom L, Ahlstedt S, Murray CS, Woodcock A, Custovic A. (2005). IgE antibody quantification and the probability of wheeze in preschool children. J Allergy Clin Immunol, 116( 4), 744-9. eScholarID:1d12138 | DOI:10.1016/j.jaci.2005.06.032
Simpson A, Custovic A. (2005). Pets and the development of allergic sensitization. Curr Allergy Asthma Rep, 5( 3), 212-20. eScholarID:1d10457
Simpson, A, Maniatis, N, Jury, F, Cakebread, J, Lowe, L, Holgate, S, Woodcock, AA, Ollier, WER, Collins, A, Custovic, A, Holloway, J, John, S. (2005). Polymorphisms in a disintegrin and metalloprotease 33 (ADAM33)predict impaired early-life lung function. Am J Respir Crit Care Med, 172(1), 55-60. eScholarID:1d10460 | DOI:10.1164/rccm.200412-1708OC
Simpson A, Custovic A. (2005). The role of allergen avoidance in the secondary prevention of atopic disorders. Curr Opin Allergy Clin Immunol, 5( 3), 223-7. eScholarID:1d11201
Lowe L, Simpson A, Woodcock AA, Morris J, Murray CS, Custovic A. (2005). Wheeze Phenotypes and Lung Function in Pre-School Children. Am J Respir Crit Care Med, 171(3), eScholarID:1d9085 | DOI:10.1164/rccm.200406-695OC
2004
Simpson A, Custovic A. (2004). Allergen avoidance in the primary prevention of asthma. Curr Opin Allergy Clin Immunol, 4( 1), 45-51. eScholarID:1d9097
Murray CS, Simpson A, Custovic A. (2004). Allergens, viruses, and asthma exacerbations. Proc Am Thorac Soc, 1( 2), eScholarID:1d11197
Woodcock AA, Lowe L, Murray CS, Simpson B, Pipis S, Kissen P, Simpson A, Custovic A, NAC Manchester Asthma and Allergy Study Group. (2004). Early life environmental control: effect on symptoms, sensitization, and lung function at age 3 years. Am J Respir Crit Care Med, 170( 4), eScholarID:1d9094 | DOI:10.1164/rccm.200401-083OC
Custovic A, Simpson A. (2004). Environmental allergen exposure, sensitisation and asthma: from whole populations to individuals at risk. Thorax, 59( 10), 825-7. eScholarID:1d9088
Lowe L, Woodcock AA, Murray CS, Murray CS, Morris J, Simpson A, Custovic A. (2004). Lung function at age 3 years: effect of pet ownership and exposure to indoor allergens. Arch Pediatr Adolesc Med, 158( 10), eScholarID:1d9087 | DOI:10.1001/archpedi.158.10.996
Custovic A, Simpson A, Woodcock AA. (2004). Manchester cohort. Pediatr Pulmonol Suppl, 26, 12-3. eScholarID:1d9099
Lowe, L, Murray, CS, Martin, L, Deas, J, Cashin, E, Poletti, G, Simpson, A, Woodcock, AA, Custovic, A. (2004). Reported versus confirmed wheeze and lung function in early life. Arch Dis Child, 89( 6), eScholarID:1d9092 | DOI:10.1136/adc.2003.038539
Simpson A, Custovic A. (2004). The role of allergen avoidance in primary and secondary prevention. Pediatr Pulmonol Suppl, 26, 225-8. eScholarID:1d9098
2003
Custovic A, Simpson B, Simpson A, Hallam C, Marolia H, Walsh D, Campbell J, Woodcock AA. (2003). Current mite, cat, and dog allergen exposure, pet ownership, and sensitization to inhalant allergens in adults. J Allergy Clin Immunol, 111( 2), 402-7. eScholarID:1d6780
Simpson A, Custovic A. (2003). Early pet exposure: friend or foe? Curr Opin Allergy Clin Immunol, 3( 1), 7-14. eScholarID:1d10290
Simpson A, Green R, Custovic A, Woodcock A, Arruda L, Chapman M. (2003). Skin test reactivity to natural and recombinant Blomia and Dermatophagoides spp. allergens among mite allergic patients in the UK. Allergy, 58( 1), 53-6. eScholarID:1d6781
Simpson A, Simpson B, Custovic A, Craven M, Woodcock AA. (2003). Stringent environmental control in pregnancy and early life: the long-term effects on mite, cat and dog allergen. Clin Exp Allergy, 33( 9), 1183-9. eScholarID:1d6779
2002
Simpson A, Simpson B, Custovic A, Cain G, Craven M, Woodcock A. (2002). Household characteristics and mite allergen levels in Manchester,UK. Clin Exp Allergy, 32( 10), 1413-9. eScholarID:1d6782
2001
Custovic A, Hallam C, Simpson B, Craven M, Simpson A, Woodcock A. (2001). Decreased prevalence of sensitization to cats with high exposure to cat allergen. J Allergy Clin Immunol, 108( 4), 537-9. eScholarID:1d6783
Custovic A, Simpson B, Simpson A, Kissen P, Woodcock A. (2001). Effect of environmental manipulation in pregnancy and early life on respiratory symptoms and atopy during first year of life: a randomised trial. Lancet, 358( 9277), 188-93. eScholarID:1d6791 | DOI:10.1016/S0140-6736(01)05406-X
Simpson A, Woodcock A, Custovic A. (2001). Housing characteristics and mite allergen levels: to humidity and beyond. Clin Exp Allergy, 31( 6), 803-5. eScholarID:1d10304
Simpson B, Custovic A, Simpson A, Hallam C, Walsh D, Marolia H, Campbell J, Woodcock A. (2001). NAC Manchester Asthma and Allergy Study (NACMAAS): risk factors for asthma and allergic disorders in adults. Clin Exp Allergy, 31( 3), 391-9. eScholarID:1d6784
2000
Custovic A, Simpson B, Simpson A, Hallam C, Craven M, Brutsche M, Woodcock A. (2000). Manchester Asthma and Allergy Study: low-allergen environment can be achieved and maintained during pregnancy and in early life. J Allergy Clin Immunol, 105( 2 Pt 1), 252-8. eScholarID:1d10320
Custovic A, Hallam C, Woodcock H, Simpson B, Houghton N, Simpson A, Woodcock A. (2000). Synthetic pillows contain higher levels of cat and dog allergen than feather pillows. Pediatr Allergy Immunol, 11( 2), 71-3. eScholarID:1d10314
1999
Custovic A, Woodcock H, Craven M, Hassall R, Hadley E, Simpson A, Woodcock A. (1999). Dust mite allergens are carried on not only large particles. Pediatr Allergy Immunol, 10( 4), 258-60. eScholarID:1d10315
Simpson A, Custovic A, Pipis S, Adisesh A, Faragher B, Woodcock A. (1999). Exhaled nitric oxide, sensitization, and exposure to allergens in patients with asthma who are not taking inhaled steroids. Am J Respir Crit Care Med, 160( 1), 45-9. eScholarID:1d10321
Hallam C, Custovic A, Simpson B, Houghton N, Simpson A, Woodcock A. (1999). Mite allergens in feather and synthetic pillows. Allergy, 54( 4), 407-8. eScholarID:1d10322
Custovic A, Simpson B, Simpson A, Hallam C, Craven M, Woodcock A. (1999). Relationship between mite, cat, and dog allergens in reservoir dust and ambient air. Allergy, 54( 6), 612-6. eScholarID:1d10318
Tunnicliffe W, Fletcher T, Hammond K, Roberts K, Custovic A, Simpson A, Woodcock A, Ayres J. (1999). Sensitivity and exposure to indoor allergens in adults with differing asthma severity. Eur Respir J, 13( 3), 654-9. eScholarID:1d10325
Green R, Simpson A, Custovic A, Faragher B, Chapman M, Woodcock A. (1999). The effect of air filtration on airborne dog allergen. Allergy, 54( 5), 484-8. eScholarID:1d10319
Green R, Simpson A, Custovic A, Woodcock A. (1999). Vacuum cleaners and airborne dog allergen. Allergy, 54( 4), 403-5. eScholarID:1d10323
Hodson T, Custovic A, Simpson A, Chapman M, Woodcock A, Green R. (1999). Washing the dog reduces dog allergen levels, but the dog needs to be washed twice a week. J Allergy Clin Immunol, 103( 4), 581-5. eScholarID:1d10326
1998
Custovic A, Simpson A, Chapman M, Woodcock A. (1998). Allergen avoidance in the treatment of asthma and atopic disorders. Thorax, 53( 1), 63-72. eScholarID:1d10334
Custovic A, Simpson A, Pahdi H, Green R, Chapman M, Woodcock A. (1998). Distribution, aerodynamic characteristics, and removal of the major cat allergen Fel d 1 in British homes. Thorax, 53( 1), 33-8. eScholarID:1d10335
Custovic A, Simpson A, Woodcock A. (1998). Importance of indoor allergens in the induction of allergy and elicitation of allergic disease. Allergy, 53( 48 Suppl), 115-20. eScholarID:1d10328
Simpson A, Hassall R, Custovic A, Woodcock A. (1998). Variability of house-dust-mite allergen levels within carpets. Allergy, 53( 6), 602-7. eScholarID:1d10333
Custovic, A., Fletcher, A., Pickering, C., Francis, H., Green, R., Smith, A., Chapman, M. & Woodcock, A (1998). Domestic allergens in public places III: house dust mite, cat, dog and cockroach allergens in British hospitals. Clin Exp Allergy, 28(1), 53-9. eScholarID:195034 | PMID:9537780
1996
Custovic, A., Green, R., Taggart, S., Smith, A., Pickering, C., Chapman, M. & Woodcock, A (1996). Domestic allergens in public places. II: Dog (Can f1) and cockroach (Bla g 2) allergens in dust and mite, cat, dog and cockroach allergens in the air in public buildings. Clin Exp Allergy, 26(11), 1246-52. eScholarID:195035 | PMID:8955573
Custovic, A., Green, R., Smith, A., Chapman, M. & Woodcock, A (1996). New mattresses: how fast do they become a significant source of exposure to house dust mite allergens? Clin Exp Allergy, 26(11), 1243-5. eScholarID:195036 | PMID:8955572
