Skip to navigation | Skip to main content | Skip to footer
Menu
Menu Search the University of Manchester siteSearch
Search type

Alternatively, use our A–Z index

Professor Angela Simpson (BA MB ChB MRCP MD PhD) - publications

List of publications

2014

  • Eeftens, Marloes; Hoek, Gerard; Gruzieva, Olena; Mölter, Anna; Agius, Raymond; Beelen, Rob; Brunekreef, Bert; Custovic, Adnan; Cyrys, Josef; Fuertes, Elaine; Heinrich, Joachim; Hoffmann, Barbara; de Hoogh, Kees; Jedynska, Aleksandra; Keuken, Menno; Klümper, Claudia; Kooter, Ingeborg; Krämer, Ursula; Korek, Michald; Koppelman, Gerard H; Kuhlbusch, Thomas A. J.; Simpson, Angela; Smit, Henriëtte A; Tsai, Ming-Yi; Wang, Meng; Wolf, Kathrin; Pershagen, Göran; Gehring, Ulrike. (2014). Elemental Composition of Particulate Matter and the Association with Lung Function. Epidemiology, eScholarID:239178
  • Belgrave, D., Granell, R., Simpson, A., Guiver, J., Bishop, C., Buchan, I., Henderson, A. & Custovic, A (2014). Developmental profiles of eczema, wheeze, and rhinitis: two population-based birth cohort studies. PLoS Med, 11(10), e1001748. eScholarID:242217 | PMID:25335105 | DOI:10.1371/journal.pmed.1001748
  • Belgrave, D., Buchan, I., Bishop, C., Lowe, L., Simpson, A. & Custovic, A (2014). Trajectories of lung function during childhood. Am J Respir Crit Care Med, 189(9), 1101-9. eScholarID:230122 | PMID:24606581 | DOI:10.1164/rccm.201309-1700OC
  • Brough, H., Simpson, A., Makinson, K., Hankinson, J., Brown, S., Douiri, A., Belgrave, D., Penagos, M., Stephens, A., McLean, W., Turcanu, V., Nicolaou, N., Custovic, A. & Lack, G (2014). Peanut allergy: effect of environmental peanut exposure in children with filaggrin loss-of-function mutations. J Allergy Clin Immunol, 134(4), 867-875.e1. eScholarID:242219 | PMID:25282568 | DOI:10.1016/j.jaci.2014.08.011
  • Bønnelykke, K., Sleiman, P., Nielsen, K., Kreiner-Møller, E., Mercader, J., Belgrave, D., den Dekker, H., Husby, A., Sevelsted, A., Faura-Tellez, G., Mortensen, L., Paternoster, L., Flaaten, R., Mølgaard, A., Smart, D., Thomsen, P., Rasmussen, M., Bonàs-Guarch, S., Holst, C., Nohr, E., Yadav, R., March, M., Blicher, T., Lackie, P., Jaddoe, V., Simpson, A., Holloway, J., Duijts, L., Custovic, A., Davies, D., Torrents, D., Gupta, R., Hollegaard, M., Hougaard, D., Hakonarson, H. & Bisgaard, H (2014). A genome-wide association study identifies CDHR3 as a susceptibility locus for early childhood asthma with severe exacerbations. Nat Genet, 46(1), 51-5. eScholarID:242250 | PMID:24241537 | DOI:10.1038/ng.2830
  • Deliu, Matea; Belgrave, Danielle; Simpson, Angela; Murray, Clare S; Kerry, Gina; Custovic, Adnan. (2014). Impact of rhinitis on asthma severity in school-age children. Allergy, eScholarID:230121 | PMID:24958195 | DOI:10.1111/all.12467
  • Fuertes, E., MacIntyre, E., Agius, R., Beelen, R., Brunekreef, B., Bucci, S., Cesaroni, G., Cirach, M., Cyrys, J., Forastiere, F., Gehring, U., Gruzieva, O., Hoffmann, B., Jedynska, A., Keuken, M., Klümper, C., Kooter, I., Korek, M., Krämer, U., Mölter, A., Nieuwenhuijsen, M., Pershagen, G., Porta, D., Postma, D., Simpson, A., Smit, H., Sugiri, D., Sunyer, J., Wang, M. & Heinrich, J (2014). Associations between particulate matter elements and early-life pneumonia in seven birth cohorts: results from the ESCAPE and TRANSPHORM projects. Int J Hyg Environ Health, 217(8), 819-29. eScholarID:242216 | PMID:24948353 | DOI:10.1016/j.ijheh.2014.05.004
  • Gruzieva, O., Gehring, U., Aalberse, R., Agius, R., Beelen, R., Behrendt, H., Bellander, T., Birk, M., de Jongste, J., Fuertes, E., Heinrich, J., Hoek, G., Klümper, C., Koppelman, G., Korek, M., Krämer, U., Lindley, S., Mölter, A., Simpson, A., Standl, M., van Hage, M., von Berg, A., Wijga, A., Brunekreef, B. & Pershagen, G (2014). Meta-analysis of air pollution exposure association with allergic sensitization in European birth cohorts. J Allergy Clin Immunol, 133(3), 767-76.e7. eScholarID:242310 | PMID:24094547 | DOI:10.1016/j.jaci.2013.07.048
  • Kljaic-Bukvic, B., Blekic, M., Aberle, N., Curtin, J., Hankinson, J., Semic-Jusufagic, A., Belgrave, D., Simpson, A. & Custovic, A (2014). Genetic variants in endotoxin signalling pathway, domestic endotoxin exposure and asthma exacerbations. Pediatr Allergy Immunol, eScholarID:230118 | PMID:24902762 | DOI:10.1111/pai.12258
  • Mölter, A., Simpson, A., Berdel, D., Brunekreef, B., Custovic, A., Cyrys, J., de Jongste, J., de Vocht, F., Fuertes, E., Gehring, U., Gruzieva, O., Heinrich, J., Hoek, G., Hoffmann, B., Klümper, C., Korek, M., Kuhlbusch, T., Lindley, S., Postma, D., Tischer, C., Wijga, A., Pershagen, G. & Agius, R (2014). A multicentre study of air pollution exposure and childhood asthma prevalence: the ESCAPE project. Eur Respir J, eScholarID:242218 | PMID:25323237 | DOI:10.1183/09031936.00083614
  • Patel, S., Custovic, A., Smith, J., Simpson, A., Kerry, G. & Murray, C (2014). Cross-sectional association of dietary patterns with asthma and atopic sensitization in childhood - in a cohort study. Pediatr Allergy Immunol, 25(6), 565-71. eScholarID:242214 | PMID:25201630 | DOI:10.1111/pai.12276
  • Prosperi, M., Marinho, S., Simpson, A., Custovic, A. & Buchan, I (2014). Predicting phenotypes of asthma and eczema with machine learning. BMC Med Genomics, 7 Suppl 1, S7. eScholarID:242247 | PMID:25077568 | DOI:10.1186/1755-8794-7-S1-S7
  • Sahiner, U., Jusufagic, A., Curtin, J., Birben, E., Belgrave, D., Sackesen, C., Simpson, A., Yavuz, T., Akdis, C., Custovic, A. & Kalayci, O (2014). Polymorphisms of endotoxin pathway and endotoxin exposure: in-vitro IgE synthesis and replication in a birth cohort. Allergy, eScholarID:231718 | PMID:25102764 | DOI:10.1111/all.12504
  • Semic-Jusufagic, A., Belgrave, D., Pickles, A., Telcian, A., Bakhsoliani, E., Sykes, A., Simpson, A., Johnston, S. & Custovic, A (2014). Assessing the association of early life antibiotic prescription with asthma exacerbations, impaired antiviral immunity, and genetic variants in 17q21: a population-based birth cohort study. Lancet Respir Med, 2(8), 621-30. eScholarID:230114 | PMID:24835835 | DOI:10.1016/S2213-2600(14)70096-7
  • Smith, N., Hankinson, J., Simpson, A., Bowyer, P. & Denning, D (2014). A prominent role for the IL1 pathway and IL15 in susceptibility to chronic cavitary pulmonary aspergillosis. Clin Microbiol Infect, 20(8), O480-8. eScholarID:242248 | PMID:24274595 | DOI:10.1111/1469-0691.12473
  • Smith, N., Hankinson, J., Simpson, A., Denning, D. & Bowyer, P (2014). Reduced expression of TLR3, TLR10 and TREM1 by human macrophages in CCPA, and novel associations of VEGFA, DENND1B and PLAT. Clin Microbiol Infect, eScholarID:242245 | PMID:24712925 | DOI:10.1111/1469-0691.12643
  • Smith, N., Bromley, M., Denning, D., Simpson, A. & Bowyer, P (2014). Elevated Levels of the Neutrophil Chemoattractant Pro-Platelet Basic Protein in Macrophages From Individuals With Chronic and Allergic Aspergillosis. J Infect Dis, eScholarID:242213 | PMID:25193981 | DOI:10.1093/infdis/jiu490
  • van et al. (2014). A novel common variant in DCST2 is associated with length in early life and height in adulthood. Hum Mol Genet, eScholarID:242215 | PMID:25281659 | DOI:10.1093/hmg/ddu510

2013

  • Belgrave, D., Simpson, A., Semic-Jusufagic, A., Murray, C., Buchan, I., Pickles, A. & Custovic, A (2013). Joint modeling of parentally reported and physician-confirmed wheeze identifies children with persistent troublesome wheezing. J Allergy Clin Immunol, 132(3), 575-583.e12. eScholarID:209733 | PMID:23906378 | DOI:10.1016/j.jaci.2013.05.041
  • Blekic, M., Kljaic Bukvic, B., Aberle, N., Marinho, S., Hankinson, J., Custovic, A. & Simpson, A (2013). 17q12-21 and asthma: interactions with early-life environmental exposures. Ann Allergy Asthma Immunol, 110(5), 347-353.e2. eScholarID:209793 | PMID:23622005 | DOI:10.1016/j.anai.2013.01.021
  • Bukvic, B., Blekic, M., Simpson, A., Marinho, S., Curtin, J., Hankinson, J., Aberle, N. & Custovic, A (2013). Asthma severity, polymorphisms in 20p13 and their interaction with tobacco smoke exposure. Pediatr Allergy Immunol, 24(1), 10-8. eScholarID:194402 | PMID:23331525 | DOI:10.1111/pai.12019
  • Bønnelykke, et al. (2013). Meta-analysis of genome-wide association studies identifies ten loci influencing allergic sensitization. Nat Genet, 45(8), 902-6. eScholarID:209732 | PMID:23817571 | DOI:10.1038/ng.2694
  • Curtin, J., Simpson, A., Belgrave, D., Semic-Jusufagic, A., Custovic, A. & Martinez, F (2013). Methylation of IL-2 promoter at birth alters the risk of asthma exacerbations during childhood. Clin Exp Allergy, 43(3), 304-11. eScholarID:194403 | PMID:23414538 | DOI:10.1111/cea.12046
  • Custovic, A., Lazic, N. & Simpson, A (2013). Pediatric asthma and development of atopy. Curr Opin Allergy Clin Immunol, 13(2), 173-80. eScholarID:209799 | PMID:23385287 | DOI:10.1097/ACI.0b013e32835e82b6
  • Gehring, U., Gruzieva, O., Agius, R., Beelen, R., Custovic, A., Cyrys, J., Eeftens, M., Flexeder, C., Fuertes, E., Heinrich, J., Hoffmann, B., de Jongste, J., Kerkhof, M., Klümper, C., Korek, M., Mölter, A., Schultz, E., Simpson, A., Sugiri, D., Svartengren, M., von Berg, A., Wijga, A., Pershagen, G. & Brunekreef, B (2013). Air Pollution Exposure and Lung Function in Children: The ESCAPE Project. Environ Health Perspect, eScholarID:209791 | PMID:24076757 | DOI:10.1289/ehp.1306770
  • Lazic, N., Roberts, G., Custovic, A., Belgrave, D., Bishop, C., Winn, J., Curtin, J., Hasan Arshad, S. & Simpson, A (2013). Multiple atopy phenotypes and their associations with asthma: similar findings from two birth cohorts. Allergy, 68(6), 764-70. eScholarID:209795 | PMID:23621120 | DOI:10.1111/all.12134
  • Mölter, A., Agius, R., de Vocht, F., Lindley, S., Gerrard, W., Custovic, A. & Simpson, A (2013). Effects of long-term exposure to PM10 and NO2 on asthma and wheeze in a prospective birth cohort. J Epidemiol Community Health, eScholarID:209734 | PMID:23999376 | DOI:10.1136/jech-2013-202681
  • Mölter, A., Agius, R., de Vocht, F., Lindley, S., Gerrard, W., Lowe, L., Belgrave, D., Custovic, A. & Simpson, A (2013). Long-term Exposure to PM10 and NO2 in Association with Lung Volume and Airway Resistance in the MAAS Birth Cohort. Environ Health Perspect, 121(10), 1232-1238. eScholarID:209729 | PMID:23777813 | DOI:10.1289/ehp.1205961
  • Prosperi, M., Sahiner, U., Belgrave, D., Sackesen, C., Buchan, I., Simpson, A., Yavuz, T., Kalayci, O. & Custovic, A (2013). Challenges in identifying asthma subgroups using unsupervised statistical learning techniques. Am J Respir Crit Care Med, 188(11), 1303-12. eScholarID:242249 | PMID:24180417 | DOI:10.1164/rccm.201304-0694OC
  • Wu, J., Hankinson, J., Kopec-Harding, K., Custovic, A. & Simpson, A (2013). Interaction between glutathione S-transferase variants, maternal smoking and childhood wheezing changes with age. Pediatr Allergy Immunol, 24(5), 501-8. eScholarID:209735 | PMID:23879774 | DOI:10.1111/pai.12086

2012

  • Fernandes BN, Boyle RJ, Gore C, Simpson A, Custovic A. (2012). Food protein-induced enterocolitis syndrome can occur in adults. Journal of Allergy and Clinicla Immunology, eScholarID:178525
  • Custovic A, Marinho S, Simpson A. (2012). Gene-environment interactions in the development of asthma and atopy. Expert Rev Respir Med, 6(3), 301-308. eScholarID:178530 | DOI:10.1586/ers.12.24
  • 4. Simpson A, Custovic A, Tepper R, Graves P, Stern D, Jones M, Hankinson J, Curtin J, Wu J, Blekic M, Bukvic B, Aberle N, Marinho S, Belgrave D, Morgan W, Martinez F. (2012). Genetic Variation in Vascular Endothelial Growth Factor-A and Lung Function. American Journal of Respiratory and Critical Care Medicine, 185(11), 1197-1204. eScholarID:178517 | DOI:10.1164/rccm.201112-2191OC
  • 3. Wan YI, Shrine NR, Soler Artigas M, Wain LV, Blakey JD, Moffatt MF, Bush A, Chung KF, Cookson WO, Strachan DP, Heaney L, Al-Momani BA, Mansur AH, Manney S, Thomson NC, Chaudhuri R, Brightling CE, Bafadhel M, Singapuri A, Niven R, Simpson A, Holloway JW, Howarth PH, Hui J, Musk AW, James AL; the Australian Asthma Genetics Consortium, Brown MA, Baltic S, Ferreira MA, Thompson PJ, Tobin MD, Sayers I, Hall IP. (2012). Genome-wide association study to identify genetic determinants of severe asthma. Thorax, 67(9), 762-768. eScholarID:178521 | DOI:10.1136/thoraxjnl-2011-201262
  • 1. Mölter A, Lindley S, de Vocht F, Agius R, Kerry G, Johnson K, Ashmore M, Terry A, i Dimitroulopoulou S, Simpson A. (In-press). Performance of a microenviromental model for estimating personal NO2 exposure in children. eScholarID:149405
  • Custovic, A. & Simpson, A (2012). The role of inhalant allergens in allergic airways disease. J Investig Allergol Clin Immunol, 22(6), 393-401; qiuz follow 401. eScholarID:209801 | PMID:23101182
  • Custovic, A., Marinho, S. & Simpson, A (2012). Gene-environment interactions in the development of asthma and atopy. Expert Rev Respir Med, 6(3), 301-8. eScholarID:195023 | PMID:22788944 | DOI:10.1586/ers.12.24
  • Custovic, A., Marinho, S. & Simpson, A (2012). Gene-environment interactions in the development of asthma and atopy. Expert Rev Respir Med, 6(3), 301-8. eScholarID:209802 | PMID:22788944 | DOI:10.1586/ers.12.24
  • Simpson, A., Custovic, A., Tepper, R., Graves, P., Stern, D., Jones, M., Hankinson, J., Curtin, J., Wu, J., Blekic, M., Bukvic, B., Aberle, N., Marinho, S., Belgrave, D., Morgan, W. & Martinez, F (2012). Genetic variation in vascular endothelial growth factor-a and lung function. Am J Respir Crit Care Med, 185(11), 1197-204. eScholarID:209785 | PMID:22461367 | DOI:10.1164/rccm.201112-2191OC

2011

  • Custovic A, Soderstrom L, Ahlstedt S, SlyPD, Simpson A, Holt PG. (2011). Allergen-specific IgG Antibody Levels Modify The Relationship Between-Allergen Specific IgE And Wheezing In Childhood In Two Population-Based Birth Cohort Studies. J Allergy Clin Immunol, 127(6), 1480-1485. eScholarID:149392
  • Murray CS, Canoy D, Buchan I, Woodcock A, Simpson A, Custovic A. (2011). Body mass index in young children and allergic disease: gender differences in a longitudinal study. Clin Exp Allergy, 41, 78-85. eScholarID:110783 | DOI:10.1111/j.1365-2222.2010.03598.x
  • 5. Custovic A, Rothers J, Stern D, Simpson A, Woodcock A, Wright AL, Nicolaou NC, Hankinson J, Halonen M, Martinez FD. (2011). Effect of day care attendance on sensitization and atopic wheezing differs by toll-like receptor 2 genotype in 2 population-based birth cohort studies. J Allergy Clin Immunol, 127(2), 390-397. eScholarID:149389 | DOI:10.1016/j.jaci.2010.10.050
  • 2. et al. (2011). Meta-analysis of genome-wide association studies identifies three new risk loci for atopic dermatitis. Nature Genetics, 44(2), 187. eScholarID:149398 | DOI:10.1038/ng.1017
  • Nicolaou N, Murray C, Belgrave D, Poorafshar M, Simpson A, Custovic A. (2011). Quantification of specific IgE to whole peanut extract and peanut components in prediction of peanut allergy. J Allergy Clin Immunol, 127(3), 684-685. eScholarID:149395 | DOI:10.1016/j.jaci.2010.12.012

2010

  • Moffatt MF... Simpson A......Cookson WO. (2010). A large-scale, consortium-based genomewide association study of asthma. New England Journal of Medicine, 363(13), 1211-1221. eScholarID:110733 | DOI:10.1056/NEJMoa0906312
  • Simpson A, Tan VYF, Winn J, Svensén M, Bishop CM, Heckerman DE, Buchan I, Custovic A. (2010). Beyond Atopy: Multiple Patterns of Sensitization in Relation to Asthma in a Birth Cohort Study. American journal of respiratory and critical care medicine, 181(11), 1200-1206. eScholarID:85281 | DOI:10.1164/rccm.200907-1101OC
  • Nicolaou N, Poorafshar M, Simpson A, Murray C, Kerry G, Härlin A, Winell H, Woodcock A, Ahlstedt S, Custovic A. (2010). Clinical Allergy Versus Tolerance Amongst Peanut Sensitized Children: Prevalence And Differentiation Using Component-Resolved Diagnostics. J Allergy Clin Immunol, 125, 191-197. eScholarID:77209 | DOI:10.1016/j.jaci.2009.10.008
  • Simpson A, Martinez F. (2010). The Role of LPS in the development of atopy in humans. Clin Exp Allergy, 40, 209-223. eScholarID:77210 | DOI:10.1111/j.1365-2222.2009.03391.x

2009

  • Patel S, Murray CS, Woodcock A, Simpson A, Custovic A. (2009). Dietary antioxidant intake, allergic sensitisation and allergic diseases in young children. Allergy, 64, 1766-1772. eScholarID:77212 | DOI:10.1111/j.1398-9995.2009.02099.x
  • Fowler SJ, Langley SJ, Truman NJ, Woodcock A, Simpson A, Custovic A. (2009). Long term effects of allergen sensitisation and exposure in adult asthma: A prospective study. World Allergy Organization Journal, 2(5), 83-90. eScholarID:77214 | DOI:10.1097/WOX.0b013e3181a45f96
  • Simpson A, Custovic A. (2009). Prevention of allergic sensitization by environmental control. Curr Allergy Asthma Rep, 9(5), 363-369. eScholarID:77211 | DOI:10.1007/s11882-009-0053-y

2008

  • Henderson J, Granell R, Heron J, Sherriff A, Simpson A, Woodcock AA, Strachan D, Shaheen S, Sterne J. (2008). Associations of wheezing phenotypes in the first 6 years of life with atopy, lung function and airway responsiveness in mid-childhood. Thorax, 63( 11), 974-80. eScholarID:1d32415 | DOI:10.1136/thx.2007.093187
  • Nicolaou NC, Simpson A, Lowe LA, Murray CS, Woodcock A, Custovic A. (2008). Day-Care Attendance, Position in Sibship and Early Childhood Wheezing: Population-Based Birth Cohort Study. J Allergy Clin Immunol, 122(3), 500-506. eScholarID:66667 | DOI:10.1016/j.jaci.2008.06.033
  • Smith JA, Drake R, Simpson A, Woodcock A, Pickles A, Custovic A. (2008). Dimensions of Respiratory Symptoms in Pre-school Children: Population-based Birth Cohort Study. Am J Respir Crit Care Med 2008, 177(12), 1358-1363. eScholarID:66661 | DOI:10.1164/rccm.200709-1419OC
  • Bisgaard H, Simpson A, Palmer CNA, Bønnelykke K, Mclean I, Mukhopadhyay S, Pipper CB, Halkjaer LB, Lipworth B, Hankinson J, Woodcock A, Custovic A. (2008). Gene-Environment Interaction in the Onset of Eczema in Infancy: Filaggrin Loss-of-Function Mutations Enhanced by Neonatal Cat Exposure. PLoS Med, 5(6), e131. eScholarID:66664 | DOI:10.1371/journal.pmed.0050131

2007

  • Marinho S, Simpson A, Söderström L, Woodcock A, Ahlstedt S, Custovic A. (2007). Quantification of atopy and the probability of rhinitis in preschool children: a population-based birth cohort study. Allergy, 62( 12), eScholarID:1d17521
  • Marinho S, Simpson A, Lowe L, Kissen P, Murray CS, Custovic A. (2007). Rhinoconjunctivitis in 5-year-old children: a population-based birth cohort study. Allergy, 62(4), 385-393. eScholarID:1d17522 | DOI:10.1111/j.1398-9995.2006.01294.x
  • Semic-Jusufagic A, Bachert C, Gevaert P, Holtappels G, Lowe L, Woodcock A, Simpson A, Custovic A. (2007). Staphylococcus aureus sensitization and allergic disease in early childhood: population-based birth cohort study. J Allergy Clin Immunol, 119(4), 930-936. eScholarID:1d17523 | DOI:10.1016/j.jaci.2006.12.639

2006

  • Marinho S, Simpson A, Custovic A. (2006). Allergen avoidance in the secondary and tertiary prevention of allergic diseases: does it work? Prim Care Respir J, 15( 3), 152-8. eScholarID:1d14400
  • Thomas M, Custovic A, Woodcock A, Morris J, Simpson A, Murray CS. (2006). Atopic wheezing and early life antibiotic exposure: a nested case-control study. Pediatr Allergy Immunol, 17( 3), 184-188. eScholarID:1d14666
  • Nicolaou N, Yiallouros P, Pipis S, Ioannou P, Simpson A, Custovic A. (2006). Domestic allergen and endotoxin exposure and allergic sensitization in Cyprus. Pediatr Allergy Immunol, 17( 1), 17-21. eScholarID:1d13025
  • Semic Jusufagic A, Simpson A, Woodcock AA. (2006). Dust mite allergen avoidance as a preventive and therapeutic strategy. Curr Allergy Asthma Rep, 6( 6), 521-6. eScholarID:1d30479
  • Simpson A, John S, Jury F, Niven R, Niven RR M, Woodcock AA, Ollier WER, Custovic A. (2006). Endotoxin Exposure, CD14 and Allergic Disease: An Interaction between Genes and the Environment. Am J Respir Crit Care Med, 174(4), 386-392. eScholarID:1d13021 | DOI:10.1164/rccm.200509-1380OC
  • Semic-Jusufagic A, Simpson A, Custovic A. (2006). Environmental exposures, genetic predisposition and allergic diseases: one size never fits all. Allergy, 61( 4), 397-9. eScholarID:1d13024
  • Keil T, Kulig M, Simpson A, Custovic A, Wickman M, Kull I, Lødrup C, Carlsen K, Smit H, Wijga A, Schmid S, Berg A, Bollrath C, Eller E, Bindslev-Jensen C, Halken S, Høst A, Heinrich J, Porta D, Forastiere F, Brunekreef B, Krämer U, Willich S, Wahn U, Lau S. (2006). European birth cohort studies on asthma and atopic diseases: I. Comparison of study designs -- a GALEN initiative. Allergy, 61(2), 221-228. eScholarID:1d13026 | DOI:10.1111/j.1398-9995.2006.00989.x
  • Keil, T, Kulig, M, Simpson, A, Custovic, A, Wickman, M, Kull, I, Lødrup Carlsen, K, Carlsen, K, Smit, H, Wijga, A, Schmid, S, Von Berg, A, Bollrath, C, Eller, E, Bindslev-Jensen, C, Halken, S, Høst, A, Heinrich, J, Fantini, M, Brunekreef, B, Krämer, U, Willich, S, Wahn, U, Lau, S. (2006). European birth cohort studies on asthma and atopic diseases: II. Comparison of outcomes and exposures--a GA2LEN initiative. Allergy, 61( 9), 1104-11. eScholarID:1d17524 | DOI:10.1111/j.1398-9995.2006.01167.x
  • Nicolaou N, Lowe L, Murray CS, Woodcock AA, Simpson A, Custovic A. (2006). Exhaled breath condensate pH and childhood asthma: unselected birth cohort study. Am J Respir Crit Care Med, 174( 3), 254-259. eScholarID:1d14402
  • Custovic A, Simpson A. (2006). What are we learning from genetic cohort studies? Paediatr Respir Rev, 7 Suppl 1, S90-2. eScholarID:1d14399

2005

  • Custovic A, Murray CS, Simpson A. (2005). Allergy and infection: understanding their relationship. Allergy, 60 Suppl 79, eScholarID:1d10458
  • Calam R, Gregg L, Simpson A, Simpson B, Woodcock AA, Custovic A. (2005). Behavior Problems Antecede the Development of Wheeze in Childhood: a Birth Cohort Study. Am J Respir Crit Care Med, 171(4), 323-7. eScholarID:1d9084 | DOI:10.1164/rccm.200406-791OC
  • Simpson A, Soderstrom L, Ahlstedt S, Murray CS, Woodcock A, Custovic A. (2005). IgE antibody quantification and the probability of wheeze in preschool children. J Allergy Clin Immunol, 116( 4), 744-9. eScholarID:1d12138 | DOI:10.1016/j.jaci.2005.06.032
  • Simpson A, Custovic A. (2005). Pets and the development of allergic sensitization. Curr Allergy Asthma Rep, 5( 3), 212-20. eScholarID:1d10457
  • Simpson, A, Maniatis, N, Jury, F, Cakebread, J, Lowe, L, Holgate, S, Woodcock, AA, Ollier, WER, Collins, A, Custovic, A, Holloway, J, John, S. (2005). Polymorphisms in a disintegrin and metalloprotease 33 (ADAM33)predict impaired early-life lung function. Am J Respir Crit Care Med, 172(1), 55-60. eScholarID:1d10460 | DOI:10.1164/rccm.200412-1708OC
  • Simpson A, Custovic A. (2005). The role of allergen avoidance in the secondary prevention of atopic disorders. Curr Opin Allergy Clin Immunol, 5( 3), 223-7. eScholarID:1d11201
  • Lowe L, Simpson A, Woodcock AA, Morris J, Murray CS, Custovic A. (2005). Wheeze Phenotypes and Lung Function in Pre-School Children. Am J Respir Crit Care Med, 171(3), eScholarID:1d9085 | DOI:10.1164/rccm.200406-695OC

2004

  • Simpson A, Custovic A. (2004). Allergen avoidance in the primary prevention of asthma. Curr Opin Allergy Clin Immunol, 4( 1), 45-51. eScholarID:1d9097
  • Murray CS, Simpson A, Custovic A. (2004). Allergens, viruses, and asthma exacerbations. Proc Am Thorac Soc, 1( 2), eScholarID:1d11197
  • Woodcock AA, Lowe L, Murray CS, Simpson B, Pipis S, Kissen P, Simpson A, Custovic A, NAC Manchester Asthma and Allergy Study Group. (2004). Early life environmental control: effect on symptoms, sensitization, and lung function at age 3 years. Am J Respir Crit Care Med, 170( 4), eScholarID:1d9094 | DOI:10.1164/rccm.200401-083OC
  • Custovic A, Simpson A. (2004). Environmental allergen exposure, sensitisation and asthma: from whole populations to individuals at risk. Thorax, 59( 10), 825-7. eScholarID:1d9088
  • Lowe L, Woodcock AA, Murray CS, Murray CS, Morris J, Simpson A, Custovic A. (2004). Lung function at age 3 years: effect of pet ownership and exposure to indoor allergens. Arch Pediatr Adolesc Med, 158( 10), eScholarID:1d9087 | DOI:10.1001/archpedi.158.10.996
  • Custovic A, Simpson A, Woodcock AA. (2004). Manchester cohort. Pediatr Pulmonol Suppl, 26, 12-3. eScholarID:1d9099
  • Lowe, L, Murray, CS, Martin, L, Deas, J, Cashin, E, Poletti, G, Simpson, A, Woodcock, AA, Custovic, A. (2004). Reported versus confirmed wheeze and lung function in early life. Arch Dis Child, 89( 6), eScholarID:1d9092 | DOI:10.1136/adc.2003.038539
  • Simpson A, Custovic A. (2004). The role of allergen avoidance in primary and secondary prevention. Pediatr Pulmonol Suppl, 26, 225-8. eScholarID:1d9098

2003

  • Custovic A, Simpson B, Simpson A, Hallam C, Marolia H, Walsh D, Campbell J, Woodcock AA. (2003). Current mite, cat, and dog allergen exposure, pet ownership, and sensitization to inhalant allergens in adults. J Allergy Clin Immunol, 111( 2), 402-7. eScholarID:1d6780
  • Simpson A, Custovic A. (2003). Early pet exposure: friend or foe? Curr Opin Allergy Clin Immunol, 3( 1), 7-14. eScholarID:1d10290
  • Simpson A, Green R, Custovic A, Woodcock A, Arruda L, Chapman M. (2003). Skin test reactivity to natural and recombinant Blomia and Dermatophagoides spp. allergens among mite allergic patients in the UK. Allergy, 58( 1), 53-6. eScholarID:1d6781
  • Simpson A, Simpson B, Custovic A, Craven M, Woodcock AA. (2003). Stringent environmental control in pregnancy and early life: the long-term effects on mite, cat and dog allergen. Clin Exp Allergy, 33( 9), 1183-9. eScholarID:1d6779

2002

  • Simpson A, Simpson B, Custovic A, Cain G, Craven M, Woodcock A. (2002). Household characteristics and mite allergen levels in Manchester,UK. Clin Exp Allergy, 32( 10), 1413-9. eScholarID:1d6782

2001

  • Custovic A, Hallam C, Simpson B, Craven M, Simpson A, Woodcock A. (2001). Decreased prevalence of sensitization to cats with high exposure to cat allergen. J Allergy Clin Immunol, 108( 4), 537-9. eScholarID:1d6783
  • Custovic A, Simpson B, Simpson A, Kissen P, Woodcock A. (2001). Effect of environmental manipulation in pregnancy and early life on respiratory symptoms and atopy during first year of life: a randomised trial. Lancet, 358( 9277), 188-93. eScholarID:1d6791 | DOI:10.1016/S0140-6736(01)05406-X
  • Simpson A, Woodcock A, Custovic A. (2001). Housing characteristics and mite allergen levels: to humidity and beyond. Clin Exp Allergy, 31( 6), 803-5. eScholarID:1d10304
  • Simpson B, Custovic A, Simpson A, Hallam C, Walsh D, Marolia H, Campbell J, Woodcock A. (2001). NAC Manchester Asthma and Allergy Study (NACMAAS): risk factors for asthma and allergic disorders in adults. Clin Exp Allergy, 31( 3), 391-9. eScholarID:1d6784
  • Custovic, A., Simpson, B., Simpson, A., Kissen, P. & Woodcock, A (2001). Effect of environmental manipulation in pregnancy and early life on respiratory symptoms and atopy during first year of life: a randomised trial. Lancet, 358(9277), 188-93. eScholarID:230316 | PMID:11476835 | DOI:10.1016/S0140-6736(01)05406-X

2000

  • Custovic A, Simpson B, Simpson A, Hallam C, Craven M, Brutsche M, Woodcock A. (2000). Manchester Asthma and Allergy Study: low-allergen environment can be achieved and maintained during pregnancy and in early life. J Allergy Clin Immunol, 105( 2 Pt 1), 252-8. eScholarID:1d10320
  • Custovic A, Hallam C, Woodcock H, Simpson B, Houghton N, Simpson A, Woodcock A. (2000). Synthetic pillows contain higher levels of cat and dog allergen than feather pillows. Pediatr Allergy Immunol, 11( 2), 71-3. eScholarID:1d10314

1999

  • Custovic A, Woodcock H, Craven M, Hassall R, Hadley E, Simpson A, Woodcock A. (1999). Dust mite allergens are carried on not only large particles. Pediatr Allergy Immunol, 10( 4), 258-60. eScholarID:1d10315
  • Simpson A, Custovic A, Pipis S, Adisesh A, Faragher B, Woodcock A. (1999). Exhaled nitric oxide, sensitization, and exposure to allergens in patients with asthma who are not taking inhaled steroids. Am J Respir Crit Care Med, 160( 1), 45-9. eScholarID:1d10321
  • Hallam C, Custovic A, Simpson B, Houghton N, Simpson A, Woodcock A. (1999). Mite allergens in feather and synthetic pillows. Allergy, 54( 4), 407-8. eScholarID:1d10322
  • Custovic A, Simpson B, Simpson A, Hallam C, Craven M, Woodcock A. (1999). Relationship between mite, cat, and dog allergens in reservoir dust and ambient air. Allergy, 54( 6), 612-6. eScholarID:1d10318
  • Tunnicliffe W, Fletcher T, Hammond K, Roberts K, Custovic A, Simpson A, Woodcock A, Ayres J. (1999). Sensitivity and exposure to indoor allergens in adults with differing asthma severity. Eur Respir J, 13( 3), 654-9. eScholarID:1d10325
  • Green R, Simpson A, Custovic A, Faragher B, Chapman M, Woodcock A. (1999). The effect of air filtration on airborne dog allergen. Allergy, 54( 5), 484-8. eScholarID:1d10319
  • Green R, Simpson A, Custovic A, Woodcock A. (1999). Vacuum cleaners and airborne dog allergen. Allergy, 54( 4), 403-5. eScholarID:1d10323
  • Hodson, T., Custovic, A., Simpson, A., Chapman, M., Woodcock, A. & Green, R (1999). Washing the dog reduces dog allergen levels, but the dog needs to be washed twice a week. J Allergy Clin Immunol, 103(4), 581-5. eScholarID:230306 | PMID:10200004

1998

  • Custovic A, Simpson A, Chapman M, Woodcock A. (1998). Allergen avoidance in the treatment of asthma and atopic disorders. Thorax, 53( 1), 63-72. eScholarID:1d10334
  • Custovic A, Simpson A, Pahdi H, Green R, Chapman M, Woodcock A. (1998). Distribution, aerodynamic characteristics, and removal of the major cat allergen Fel d 1 in British homes. Thorax, 53( 1), 33-8. eScholarID:1d10335
  • Custovic A, Simpson A, Woodcock A. (1998). Importance of indoor allergens in the induction of allergy and elicitation of allergic disease. Allergy, 53( 48 Suppl), 115-20. eScholarID:1d10328
  • Simpson A, Hassall R, Custovic A, Woodcock A. (1998). Variability of house-dust-mite allergen levels within carpets. Allergy, 53( 6), 602-7. eScholarID:1d10333
  • Custovic, A., Fletcher, A., Pickering, C., Francis, H., Green, R., Smith, A., Chapman, M. & Woodcock, A (1998). Domestic allergens in public places III: house dust mite, cat, dog and cockroach allergens in British hospitals. Clin Exp Allergy, 28(1), 53-9. eScholarID:195034 | PMID:9537780

1996

  • Custovic, A., Green, R., Taggart, S., Smith, A., Pickering, C., Chapman, M. & Woodcock, A (1996). Domestic allergens in public places. II: Dog (Can f1) and cockroach (Bla g 2) allergens in dust and mite, cat, dog and cockroach allergens in the air in public buildings. Clin Exp Allergy, 26(11), 1246-52. eScholarID:195035 | PMID:8955573
  • Custovic, A., Green, R., Smith, A., Chapman, M. & Woodcock, A (1996). New mattresses: how fast do they become a significant source of exposure to house dust mite allergens? Clin Exp Allergy, 26(11), 1243-5. eScholarID:195036 | PMID:8955572