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Dr Jacky Smith (MB, ChB, MRCP, PhD) - research

Research interests

Research interests include:

Measurement of cough and the cough reflex

The role of gastro-oesophageal reflux in chronic cough

Mechanisms of sensitisation of the cough reflex

Testing of novel anti-tussive agents

Collaborators and affiliated staff

Affiliated Staff
Ms Danielle Yuill (Research Project Co-ordinator)
Dr Angela Kelsall (Post doctoral Pulmonary Physiologist)
Dr Kevin McGuinness (Senior Clinical Engineer)
Dr Peter West (Research Associate)
Dr Demi Valdramidou (Research Associate)
Dr Alison Watson (Research Associate)
Dr Rayid Abdulqawi (Clinical Research Fellow and PhD student)
Dr Amelie Harle (NIHR Clinical Research Fellow and PhD Student)
Ms Rachel Dockry (Research Assisstant)
Ms Kimberly Holt (Research Assistant)
Ms Simone Oliver (Industrial Placement Student)
 
 

Academic Collaborators

Prof Lesley Houghton, Mayo Clinic, Florida, US

Prof Doug Corfield, University of Manchester

Mr Andy Camilleri, ENT Surgery, UHSM

Mr Simon Galloway, GI Surgery, UHSM

Professor Peter Calverley and Dr John Earis, University Hospital Aintree, University of Liverpool

Professor Neil Thomson, Division of Immunology, Infection & Inflammation, University of Glasgow

Prof Jeff Pearson and Dr Chris Ward, School of Clinical Medical Sciences, Newcastle University

Dr Andrea Aliverti, Dipartimento di Bioingegneria, Politecnico di Milano, Milano, Italy

Prof Maria Belvisi, National Heart and Lung Institute, Imperial College, London

Dr Brendan Canning, Johns Hopkins Medical Institutions, Balitmore, Maryland

 

Industrial Collaborators

Vitalograph Ltd, Maids Moreton, Buckingham, UK

GlaxoSmithKilne, Discovery Medicine, Respiratory CEDD, Stevenage, UK

Schering Plough Corp., Kenilworth, New Jersey, USA

Procter & Gamble, UK

Pfizer, NY, USA

Methodological knowledge

Clinical research skills: bronchial challenge testing, cough reflex sensitivity testing, pulmonary function testing, exhaled nitric oxide measurement, sputum induction, endo-bronchial biopsy, brushing and lavage, optico-electronic plethysmography, intra-oesophageal and gastric balloon pressure measurements

Clinical trials experience: design, applying for ethical approval, patient recruitment, data collection and analysis, including clinical trials of investigational medicinal products for the treatment of cough.
Statistics and data analysis skills: I have an interest in advanced statistical techniques such as factor analysis, cluster analysis and recently structural equation modelling.
Signal Processing Skills: I have a basic understanding of acoustic signal processing and speech recognition techniques from a close collaboration with computer scientists and engineers