Gwyer Findlay E, Villegas-Mendez A, de Souza JB, Inkson CA, Shaw TN, Saris CJ, Hunter CA, Riley EM, Couper KN. (2013). IL-27 Receptor Signaling Regulates CD4+ T Cell Chemotactic Responses during Infection. Journal of Immunology, 190(9), 4553-4661. eScholarID:193712
Villegas-Mendez A, de Souza JB, Lavelle SW, Gwyer Findlay E, Shaw TN, van Rooijen N, Saris CJ, Hunter CA, Riley EM, Couper KN. (2013). IL-27 Receptor Signalling Restricts the Formation of Pathogenic, Terminally Differentiated Th1 Cells during Malaria Infection by Repressing IL-12 Dependent Signals. PLoS Pathogens, 9(4), eScholarID:193715
2012
Villegas-Mendez A, Greig R, Shaw TN, de Souza JB, Gwyer Findlay E, Stumhofer JS, Hafalla JC, Blount DG, Hunter CA, Riley EM, Couper KN. (2012). IFN-γ-producing CD4+ T cells promote experimental cerebral malaria by modulating CD8+ T cell accumulation within the brain. Journal of Immunology, 189(2), 968-979. eScholarID:193718
Hafalla, J., Claser, C., Couper, K., Grau, G., Renia, L., de Souza, J. & Riley, E (2012). The CTLA-4 and PD-1/PD-L1 inhibitory pathways independently regulate host resistance to Plasmodium-induced acute immune pathology. PLoS Pathog, 8(2), e1002504. eScholarID:158621 | PMID:22319445 | DOI:10.1371/journal.ppat.1002504
2011
Villegas-Mendez, A., de Souza, J., Murungi, L., Hafalla, J., Shaw, T., Greig, R., Riley, E. & Couper, K (2011). Heterogeneous and tissue-specific regulation of effector T cell responses by IFN-gamma during Plasmodium berghei ANKA infection. J Immunol, 187(6), 2885-97. eScholarID:158624 | PMID:21880980 | DOI:10.4049/jimmunol.1100241
2010
Riley EM, Couper KN, Helmby H, Hafalla JC, de Souza JB, Langhorne J, Jarra WB, Zavala F. (2010). Neuropathogenesis of human and murine malaria. Trends In Parasitology, 26(6), 277-278. eScholarID:193844
Couper, K., Barnes, T., Hafalla, J., Combes, V., Ryffel, B., Secher, T., Grau, G., Riley, E. & de Souza, J (2010). Parasite-derived plasma microparticles contribute significantly to malaria infection-induced inflammation through potent macrophage stimulation. PLoS Pathog, 6(1), e1000744. eScholarID:158623 | PMID:20126448 | DOI:10.1371/journal.ppat.1000744
Findlay, E., Greig, R., Stumhofer, J., Hafalla, J., de Souza, J., Saris, C., Hunter, C., Riley, E. & Couper, K (2010). Essential role for IL-27 receptor signaling in prevention of Th1-mediated immunopathology during malaria infection. J Immunol, 185(4), 2482-92. eScholarID:158622 | PMID:20631310 | DOI:10.4049/jimmunol.0904019
de Souza, J., Hafalla, J., Riley, E. & Couper, K (2010). Cerebral malaria: why experimental murine models are required to understand the pathogenesis of disease. Parasitology, 137(5), 755-72. eScholarID:158625 | PMID:20028608 | DOI:10.1017/S0031182009991715
de Souza, J., Runglall, M., Corran, P., Okell, L., Kumar, S., Gowda, D., Couper, K. & Riley, E (2010). Neutralization of malaria glycosylphosphatidylinositol in vitro by serum IgG from malaria-exposed individuals. Infect Immun, 78(9), 3920-9. eScholarID:158620 | PMID:20566691 | DOI:10.1128/IAI.00359-10
2009
Couper, K., Lanthier, P., Perona-Wright, G., Kummer, L., Chen, W., Smiley, S., Mohrs, M. & Johnson, L (2009). Anti-CD25 antibody-mediated depletion of effector T cell populations enhances susceptibility of mice to acute but not chronic Toxoplasma gondii infection. J Immunol, 182(7), 3985-94. eScholarID:158631 | PMID:19299696 | DOI:10.4049/jimmunol.0803053
2008
Couper, K., Blount, D., Wilson, M., Hafalla, J., Belkaid, Y., Kamanaka, M., Flavell, R., de Souza, J. & Riley, E (2008). IL-10 from CD4CD25Foxp3CD127 adaptive regulatory T cells modulates parasite clearance and pathology during malaria infection. PLoS Pathog, 4(2), e1000004. eScholarID:158628 | PMID:18401464 | DOI:10.1371/journal.ppat.1000004
Couper, K., Blount, D. & Riley, E (2008). IL-10: the master regulator of immunity to infection. J Immunol, 180(9), 5771-7. eScholarID:158629 | PMID:18424693
2007
Couper, K., Blount, D., de Souza, J., Suffia, I., Belkaid, Y. & Riley, E (2007). Incomplete depletion and rapid regeneration of Foxp3+ regulatory T cells following anti-CD25 treatment in malaria-infected mice. J Immunol, 178(7), 4136-46. eScholarID:158630 | PMID:17371969
Couper, K., Blount, D., Hafalla, J., van Rooijen, N., de Souza, J. & Riley, E (2007). Macrophage-mediated but gamma interferon-independent innate immune responses control the primary wave of Plasmodium yoelii parasitemia. Infect Immun, 75(12), 5806-18. eScholarID:158627 | PMID:17923512 | DOI:10.1128/IAI.01005-07
2005
Couper, K., Chen, W., Houston, K., Harnett, W. & Johnson, L (2005). ES-62 is unable to modulate Toxoplasma gondii-driven Th1 responses and pathology. Parasite Immunol, 27(4), 147-50. eScholarID:158626 | PMID:15910423 | DOI:10.1111/j.1365-3024.2005.00755.x
Couper, K., Phillips, R., Brombacher, F. & Alexander, J (2005). Parasite-specific IgM plays a significant role in the protective immune response to asexual erythrocytic stage Plasmodium chabaudi AS infection. Parasite Immunol, 27(5), 171-80. eScholarID:158634 | PMID:15987340 | DOI:10.1111/j.1365-3024.2005.00760.x
Couper, K., Roberts, C., Brombacher, F., Alexander, J. & Johnson, L (2005). Toxoplasma gondii-specific immunoglobulin M limits parasite dissemination by preventing host cell invasion. Infect Immun, 73(12), 8060-8. eScholarID:158633 | PMID:16299300 | DOI:10.1128/IAI.73.12.8060-8068.2005
Smiley, S., Lanthier, P., Couper, K., Szaba, F., Boyson, J., Chen, W. & Johnson, L (2005). Exacerbated susceptibility to infection-stimulated immunopathology in CD1d-deficient mice. J Immunol, 174(12), 7904-11. eScholarID:158632 | PMID:15944296
2003
Couper, K., Nielsen, H., Petersen, E., Roberts, F., Roberts, C. & Alexander, J (2003). DNA vaccination with the immunodominant tachyzoite surface antigen (SAG-1) protects against adult acquired Toxoplasma gondii infection but does not prevent maternofoetal transmission. Vaccine, 21(21-22), 2813-20. eScholarID:158635 | PMID:12798622 | DOI:10.1016/S0264-410X(03)00163-4
