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Dr Shen-Hsi Yang (PhD) - publications

List of publications

2013

  • O'Donnell, A., Yang, S. & Sharrocks, A (2013). PARP1 orchestrates variant histone exchange in signal-mediated transcriptional activation. EMBO Rep, 14(12), 1084-91. eScholarID:218110 | PMID:24145797 | DOI:10.1038/embor.2013.164
  • Yang, S., Sharrocks, A. & Whitmarsh, A (2013). MAP kinase signalling cascades and transcriptional regulation. Gene, 513(1), 1-13. eScholarID:218105 | PMID:23123731 | DOI:10.1016/j.gene.2012.10.033
  • Yang, S. & Sharrocks, A (2013). Ubc9 acetylation: a new route for achieving specificity in substrate SUMOylation. EMBO J, 32(6), 773-4. eScholarID:218092 | PMID:23395903 | DOI:10.1038/emboj.2013.21

2012

  • Yang, S., Kalkan, T., Morrisroe, C., Smith, A. & Sharrocks, A (2012). A genome-wide RNAi screen reveals MAP kinase phosphatases as key ERK pathway regulators during embryonic stem cell differentiation. PLoS Genet, 8(12), e1003112. eScholarID:218078 | PMID:23271975 | DOI:10.1371/journal.pgen.1003112

2010

  • Merrill, J., Melhuish, T., Kagey, M., Yang, S., Sharrocks, A. & Wotton, D (2010). A role for non-covalent SUMO interaction motifs in Pc2/CBX4 E3 activity. PLoS One, 5(1), e8794. eScholarID:218076 | PMID:20098713 | DOI:10.1371/journal.pone.0008794
  • Yang, S. & Sharrocks, A (2010). MAP Kinase: SUMO pathway interactions. Methods Mol Biol, 661, 343-67. eScholarID:218107 | PMID:20811994 | DOI:10.1007/978-1-60761-795-2_21
  • Yang, S. & Sharrocks, A (2010). The SUMO E3 ligase activity of Pc2 is coordinated through a SUMO interaction motif. Mol Cell Biol, 30(9), 2193-205. eScholarID:218095 | PMID:20176810 | DOI:10.1128/MCB.01510-09

2008

  • O'Donnell, A., Yang, S. & Sharrocks, A (2008). MAP kinase-mediated c-fos regulation relies on a histone acetylation relay switch. Mol Cell, 29(6), 780-5. eScholarID:218104 | PMID:18374651 | DOI:10.1016/j.molcel.2008.01.019

2007

  • Guo, B., Yang, S., Witty, J. & Sharrocks, A (2007). Signalling pathways and the regulation of SUMO modification. Biochem Soc Trans, 35(Pt 6), 1414-8. eScholarID:218085 | PMID:18031234 | DOI:10.1042/BST0351414
  • Zhang, L., Yang, S. & Sharrocks, A (2007). Rev7/MAD2B links c-Jun N-terminal protein kinase pathway signaling to activation of the transcription factor Elk-1. Mol Cell Biol, 27(8), 2861-9. eScholarID:218093 | PMID:17296730 | DOI:10.1128/MCB.02276-06

2006

  • Yang SH, Galanis A, Witty J, Sharrocks AD. (2006). An extended consensus motif enhances the specificity of substrate modification by SUMO. EMBO J, 25(21), 5083-93. eScholarID:1c5478 | PMID:17036045 | DOI:10.1038/sj.emboj.7601383
  • Yang, S. & Sharrocks, A (2006). Interplay of the SUMO and MAP kinase pathways. Ernst Schering Res Found Workshop, (57), 193-209. eScholarID:218082 | PMID:16568956
  • Yang, S. & Sharrocks, A (2006). Convergence of the SUMO and MAPK pathways on the ETS-domain transcription factor Elk-1. Biochem Soc Symp, (73), 121-9. eScholarID:218079 | PMID:16626293
  • Yang, S. & Sharrocks, A (2006). PIASxalpha differentially regulates the amplitudes of transcriptional responses following activation of the ERK and p38 MAPK pathways. Mol Cell, 22(4), 477-87. eScholarID:218089 | PMID:16713578 | DOI:10.1016/j.molcel.2006.03.037

2005

  • Yang SH, Sharrocks AD. (2005). PIASx acts as an Elk-1 coactivator by facilitating derepression. The EMBO journal, 24(12), 2161-71. eScholarID:1c5975 | PMID:15920481 | DOI:10.1038/sj.emboj.7600690

2004

  • Yang, S. & Sharrocks, A (2004). SUMO promotes HDAC-mediated transcriptional repression. Mol Cell, 13(4), 611-7. eScholarID:218090 | PMID:14992729

2003

  • Li, Q., Yang, S., Maeda, Y., Sladek, F., Sharrocks, A. & Martins-Green, M (2003). MAP kinase phosphorylation-dependent activation of Elk-1 leads to activation of the co-activator p300. EMBO J, 22(2), 281-91. eScholarID:218080 | PMID:12514134 | DOI:10.1093/emboj/cdg028
  • Yang, S., Jaffray, E., Hay, R. & Sharrocks, A (2003). Dynamic interplay of the SUMO and ERK pathways in regulating Elk-1 transcriptional activity. Mol Cell, 12(1), 63-74. eScholarID:218081 | PMID:12887893
  • Yang, S., Jaffray, E., Senthinathan, B., Hay, R. & Sharrocks, A (2003). SUMO and transcriptional repression: dynamic interactions between the MAP kinase and SUMO pathways. Cell Cycle, 2(6), 528-30. eScholarID:218097 | PMID:14504467
  • Yang, S., Sharrocks, A. & Whitmarsh, A (2003). Transcriptional regulation by the MAP kinase signaling cascades. Gene, 320, 3-21. eScholarID:218091 | PMID:14597384

2002

  • Yang SH, Bumpass DC, Perkins ND, Sharrocks AD. (2002). The ETS domain transcription factor Elk-1 contains a novel class of repression domain. Molecular and cellular biology, 22(14), 5036-46. eScholarID:1c1884 | PMID:12077333 | DOI:10.1128/MCB.22.14.5036-5046.2002

2001

  • Yang SH, Vickers E, Brehm A, Kouzarides T, Sharrocks AD. (2001). Temporal recruitment of the mSin3A-histone deacetylase corepressor complex to the ETS domain transcription factor Elk-1. Molecular and cellular biology, 21(8), 2802-14. eScholarID:1c1890 | PMID:11283259 | DOI:10.1128/MCB.21.8.2802-2814.2001
  • Galanis, A., Yang, S. & Sharrocks, A (2001). Selective targeting of MAPKs to the ETS domain transcription factor SAP-1. J Biol Chem, 276(2), 965-73. eScholarID:218096 | PMID:11029469 | DOI:10.1074/jbc.M007697200

2000

  • Sharrocks, A., Yang, S. & Galanis, A (2000). Docking domains and substrate-specificity determination for MAP kinases. Trends Biochem Sci, 25(9), 448-53. eScholarID:218074 | PMID:10973059

1999

  • Brown, L., Yang, S., Hair, A., Galanis, A. & Sharrocks, A (1999). Molecular characterization of a zebrafish TCF ETS-domain transcription factor. Oncogene, 18(56), 7985-93. eScholarID:218111 | PMID:10637509 | DOI:10.1038/sj.onc.1203197
  • Yang, S., Galanis, A. & Sharrocks, A (1999). Targeting of p38 mitogen-activated protein kinases to MEF2 transcription factors. Mol Cell Biol, 19(6), 4028-38. eScholarID:218098 | PMID:10330143
  • Yang, S., Shore, P., Willingham, N., Lakey, J. & Sharrocks, A (1999). The mechanism of phosphorylation-inducible activation of the ETS-domain transcription factor Elk-1. EMBO J, 18(20), 5666-74. eScholarID:218100 | PMID:10523309 | DOI:10.1093/emboj/18.20.5666

1998

  • Yang, S., Whitmarsh, A., Davis, R. & Sharrocks, A (1998). Differential targeting of MAP kinases to the ETS-domain transcription factor Elk-1. EMBO J, 17(6), 1740-9. eScholarID:218077 | PMID:9501095 | DOI:10.1093/emboj/17.6.1740
  • Yang, S., Yates, P., Whitmarsh, A., Davis, R. & Sharrocks, A (1998). The Elk-1 ETS-domain transcription factor contains a mitogen-activated protein kinase targeting motif. Mol Cell Biol, 18(2), 710-20. eScholarID:218101 | PMID:9447967

1997

  • Whitmarsh, A., Yang, S., Su, M., Sharrocks, A. & Davis, R (1997). Role of p38 and JNK mitogen-activated protein kinases in the activation of ternary complex factors. Mol Cell Biol, 17(5), 2360-71. eScholarID:218088 | PMID:9111305
  • Yang, S., Yates, P., Whitmarsh, A., Davis, R. & Sharrocks, A (1997). The regulation of TCF transcription factors by MAP kinase cascades. Biochem Soc Trans, 25(2), 153S. eScholarID:218094 | PMID:9191197