Dr Stefan Meyer (MD PhD MRCPCH) - publications

2012

• Samarasinghe S, Steward C, Hiwarkar P, Saif MA, Hough R , Webb D, Norton A, Lawson S, Qureshi A, Connor P, Carey P, Skinner R, Vora A, Pelidis M, Gibson B, Stewart G, Keogh S, Goulden N, Bonney D, Stubbs M, Amrolia P, Rao K, Meyer S, Wynn R, Veys P. (2012). Excellent outcome of matched unrelated donor transplantation in paediatric aplastic anaemia: A United Kingdom Multicentre Retrospective Experience. British Journal of haematology, eScholarID:157692
• Anderson et al. (2012). Mutations in CTC1, encoding conserved telomere maintenance component 1, cause Coats plus. Nature genetics, 44(3), 338-42. eScholarID:157694

2011

• Biswas K, Das R, Alter BP, Kuznetsov SG, Stauffer SL, North SLG, Burkett S, Brody LC, Meyer S, Byrd AR, Sharan SK. (2011). A comprehensive study to classify BRCA2 variants associated with Fanconi Anemia using mouse ES cell-based functional assay. Blood, eScholarID:128047 | DOI:10.1182/blood-2010-12-324541
• Lugthart S, Figueroa ME, Bindels E, Skrabanek L, Valk PJM, Li Y, Meyer S, Erpelinck-Verschueren C, Greally J, Löwenberg B, Melnick A, Delwel R. (2011). Aberrant DNA hypermethylation signature in acute myeloid leukemia directed by EVI1. Blood, 117, 234-241. eScholarID:128049 | DOI:10.1182/blood-2010-04-281337
• Meyer S, Bristow C, Wappett M, Pepper S, Whetton AD, Hanenberg H, Neitzel H, Wlodarski MW, Ebell W , Tönnies H. (2011). Fanconi Anaemia (FA)-associated 3q gains in leukaemic transformation consistently target EVI1, but do not affect low TERC expression in FA. Blood, 117, 6047-6050. eScholarID:128048 | DOI:10.1182/blood-2011-03-343897
• Thathia, S., Ferguson, S., Gautrey, H., van Otterdijk, S., Hili, M., Rand, V., Moorman, A., Meyer, S., Brown, R. & Strathdee, G (2011). Epigenetic inactivation of TWIST2 in acute lymphoblastic leukemia modulates proliferation, cell survival and chemosensitivity. Haematologica, eScholarID:140380 | PMID:22058208 | DOI:10.3324/haematol.2011.049593

2010

• Clarkson, J., Worthington, H., Furness, S., McCabe, M., Khalid, T. & Meyer, S (2010). Interventions for treating oral mucositis for patients with cancer receiving treatment. Cochrane Database Syst Rev, (8), CD001973. eScholarID:103459 | PMID:20687070 | DOI:10.1002/14651858.CD001973.pub4
• Worthington, H., Clarkson, J., Bryan, G., Furness, S., Glenny, A., Littlewood, A., McCabe, M., Meyer, S. & Khalid, T (2010). Interventions for preventing oral mucositis for patients with cancer receiving treatment. Cochrane Database Syst Rev, 12, CD000978. eScholarID:103457 | PMID:21154347 | DOI:10.1002/14651858.CD000978.pub4
• Worthington, H., Clarkson, J., Khalid, T., Meyer, S. & McCabe, M (2010). Interventions for treating oral candidiasis for patients with cancer receiving treatment. Cochrane Database Syst Rev, (7), CD001972. eScholarID:103460 | PMID:20614427 | DOI:10.1002/14651858.CD001972.pub4

2007

• Meyer, S, Fergusson, W, Whetton, A, Moreira-Leite F, Pepper SD, Miller, CCJ, Saunders EK, White, DDJ, Will AM, Eden, OB, Ikeda H, Ullmann R, Tuerkmen S, Gerlach A, Klopocki E, Tönnies H. (2007). Amplification and translocation of 3q26 with overexpression of EVI1 in Fanconi anemia derived childhood acute myeloid leukemia with biallelic FANCD1/BRCA2 disruption. Genes Chromosome Cancer, 46 (4), 359-372. eScholarID:1d27524 | DOI:10.1002/gcc.20417
• Strathdee, G, Holyoake, T, Sim, A, Parker, A, Oscier, D, Melo, J, Meyer, S, Eden, OB, Dickinson, A, Mountford, J, Jorgensen, H, Soutar, R, Brown, R. (2007). Inactivation of HOXA genes by hypermethylation in myeloid and lymphoid malignancy is frequent and associated with poor prognosis. Clin Cancer Res, 13( 17), eScholarID:1d20073 | DOI:10.1158/1078-0432.CCR-07-0919

2006

• Meyer S, Eden T, Brennan B, Stevens R, Makin GWJ, Wynn RF, Carr T, Will A. (2006). Acquired chemosensitivity after insect bite in a boy with leukaemia. Br J Haematol, 134( 2), 244-5. eScholarID:1d30545
• Meyer S, Eden OB, Kalirai H. (2006). Dexamethasone protects against cisplatin-induced activation of the mitochondrial apoptotic pathway in human osteosarcoma cells. Cancer Biol Ther, 5, 915-920. eScholarID:1d15557
• Isaac H, Patel L, Meyer S, Cusick C, Hall C, Price DA, Clayton PE. (2006). Efficacy of a monthly compared to 3-monthly depot GnRH analogue (goserelin) in the treatment of children with central precocious puberty. Hormone Research, 68, 157-163. eScholarID:1d27670
• Meyer S, White DDJ, Will AM, Eden OB, Sim A, Brown R, Strathdee G. (2006). No evidence of significant silencing of Fanconi genes FANCF and FANCB or Nijmegen breakage syndrome gene NBS1 by DNA hyper-methylation in sporadic childhood leukaemia. Br J Haematol in press, 134, 61-63. eScholarID:1d13067 | DOI:10.1111/j.1365-2141.2006.06107.x
• Meyer, S, Barber, L, White, DDJ, Andrew M. Will, Birch, JM, Janice A. Kohler, Ersfeld, KK.., Eric Blom, Hans Joenje, Eden, OB, Taylor, GM. (2006). Spectrum and significance of variants and mutations in the Fanconi anaemia group G gene in children with sporadic acute myeloid leukaemia. British Journal of Haematology, 133, 284-293. eScholarID:1d13048 | DOI:10.1111/j.1365-2141.2006.05985.x
• Barber L, Meyer S, White DDJ, Andrew MW, Eden OB, Taylor GM. (2006). The association between FANCD1/BRCA2 mutations and leukaemia - response to Alter. British Journal Of Haematology, 133(4), eScholarID:17d389

2005

• Meyer, S, Fergusson, W, Oostra AB , Medhurst AL, Waisfisz Q, de Winter JP, Chen F, Carr TF, Clayton-Smith, J, Clancy, T, Green M, Barber, L, Eden, OB, Will AM, Joenje H, Taylor, GM. (2005). A cross- linker sensitive myeloid leukaemia cell line from a 2-year-old boy with severe Fanconi Anaemia and bi-allelic FANCD1/BRCA2 mutations. Genes Chromosomes and Cancer, 42(4), 404-415. eScholarID:1d10145 | DOI:10.1002/gcc.20153
• Meyer, S, Fergusson, W, Oostra, A, Medhurst, A, Waisfisz, Q, de Winter, J, Chen, F, Carr, T, Clayton-Smith, J, Clancy, T, Green, M, Barber, L, Eden, O, Will, A, Joenje, H, Taylor, G. (2005). A cross-linker-sensitive myeloid leukemia cell line from a 2-year-old boy with severe Fanconi anemia and biallelic FANCD1/BRCA2 mutations. Genes Chromosomes Cancer, 42( 4), eScholarID:1d30840
• Barber L, Barlow R, Meyer S, White DDJ, Will AM, Eden OB, Taylor GM. (2005). Inherited FANCD1/BRCA2 exon 7 splice mutations associated with acute myeloid leukaemia in Fanconi anaemia D1 are not found in sporadic childhood leukaemia. British Journal Of Haematology, 130 (5), 796-797. eScholarID:1d26679

2004

• Chen F, Medhurst AL, De Winter JP, Waisfisz Q, Rooimans MA, Oostra AB, Meyer, S, Zhang KJ, Xia B, Pals G, Arwert F, Zwaan CM, Joenje H. (2004). Apparent absence of BRCA2 protein in a proportion of acute myeloid leukemia cell lines. Leukemia, 18, eScholarID:1d10143
• Meyer, S, Kingston, H, Taylor AM, Byrd PJ, Last JIK, Brennan, BMD, Trueman S, Kelsey, A, Taylor, GM, Eden, OB. (2004). Rhabdomyosarcoma in Nijmegen Breakage Syndrome: strong association with perianal primary site. Cancer Genetics and Cytogenetics, 154, 169-174. eScholarID:1d10045
• Meyer, S, Kingston, H, Taylor, A, Byrd, P, Last, J, Brennan, B, Trueman, S, Kelsey, A, Taylor, G, Eden, O. (2004). Rhabdomyosarcoma in Nijmegen breakage syndrome: strong association with perianal primary site. Cancer Genet Cytogenet, 154( 2), eScholarID:1d29224

2003

• Barber L, McGrath HEN, Meyer S, Will AM, Birch JM, Eden OB, Taylor GM. (2003). Constitutional sequence variation in the Fanconi anaemia group C (FANCC) gene in childhood acute myeloid leukaemia. British Journal Of Haematology, 121 (1), eScholarID:1d25387

2002

• Stevens RF, Meyer S. (2002). Fanconi and Glanzmann - the men and their works. Brit J Haematol, 119(4), eScholarID:1d6556
• Robson H, Meyer S, Shalet SM, Anderson E, Roberts SA, Eden OB. (2002). Platinum agents in the treatment of osteosarcoma: efficacy of cistplatin vs. carboplatin in human osteosarcoma cell lines. Medical & Pediatric Oncology, 39 (6), eScholarID:1d3890

2000

• Meyer S, Thornley M, Wynn RF, Brennan BMD, Carr T, Wraith JE, Will AM. (2000). Donor bone marrow from sibling with inborn error of metabolism for treatment of acute leukaemia – clinical and biochemical consequences for the non affected recipient. Bone Marrow Transplantation, 25, eScholarID:1d3894
• Meyer S, Bradbury AJ. (2000). Infant air travel, bronchiolitis and the environment. Archives of Diseases in Childhood, 83, eScholarID:1d3895
• Meyer S, Bruce J, Kelsey A, Eden OB. (2000). Pseudosarcoma of the bladder associated with residual urachus in a three year old girl. Paediatric Surgery International, 16, eScholarID:1d3892