Recruitment call for skin lipids and bacteria study

Researchers from the University of Manchester are seeking participants for the study: ‘Determining the critical relationship between human epidermal lipids and microbiota in sustaining healthy skin ageing - how do skin lipids and bacteria change with age?’

Study summary

As skin ages, we see a decline in skin barrier function, which can leave elderly people vulnerable to skin damage. We believe that these changes may partly be due to changes in the skin’s lipid profile, and changes in the bacteria living on the skin.

In this study, we plan to investigate how the skin lipids and bacteria change as we age. We will examine the lipid composition of the skin, the function of the skin barrier, and the number and type of microbes that are found on the skin, at different body sites. We hope to identify changes in these profiles, and the relationship between the two.

Who can take part?

Healthy men and women aged over 70.

What will the research involve?

This study will involve a single visit to the study clinic. During this visit you will have your skin health assessed (including measurements of pH and water loss), then we will use wet swabs to sample surface bacteria, and adhesive tape strips to sample the very top layer of your skin. We also need a small number of volunteers to provide two skin biopsies (6 mm diameter) from the buttock (optional).

Where will the research take place?

Salford Royal Hospital


You will be reimbursed for your time and inconvenience.

For more information please contact susan.hawksworth@manchester.ac.uk.

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