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Dr Reza Aghamohammadzadeh (MB ChB (Honours), MRCP (UK), PhD) - publications

List of publications


  • Khavandi, K., Aghamohammadzadeh, R., Luckie, M., & Brownrigg, J. (2017). ABNORMAL REMODELING OF SUBCUTANEOUS SMALL ARTERIES IS ASSOCIATED WITH EARLY DIASTOLIC IMPAIRMENT IN METABOLIC SYNDROME. American Heart Association. Journal. Cardiovascular and Cerebrovascular Disease, 6, [e004603]. DOI: 10.1161/JAHA.116.004603. Publication link: 4ae7de44-3f63-47bc-9d49-2bdb203a8f25


  • Aghamohammadzadeh, R., Zhang, Y. Y., Stephens , T. E., Arons , E., Zaman , P., Polach, K. J., ... Maron , B. (2016). Up-regulation of the mammalian target of rapamycin complex 1 subunit Raptor by aldosterone induces abnormal pulmonary artery smooth muscle cell survival patterns to promote pulmonary arterial hypertension. The FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 30(7), 2511-2527. DOI: 10.1096/fj.201500042. Publication link: 2bc42031-5f67-4331-96cb-6431f4c37587


  • Aghamohammadzadeh, D. O., Heagerty, A., Berbari, A. (Ed.), & Mancia, G. (Ed.) (2015). Arterial disorders: Definition and epidemiology. In Arterial disorders. Springer Verlag. . Publication link: 28755106-4032-4172-91e3-538cc33d0937
  • Aghamohammadzadeh, R., Unwin, R. D., Greenstein, A. S., & Heagerty, A. M. (2015). Effects of Obesity on Perivascular Adipose Tissue Vasorelaxant Function: Nitric Oxide, Inflammation and Elevated Systemic Blood Pressure. Journal of Vascular Research, 52(5), 299-305. DOI: 10.1159/000443885. Publication link: 5e735810-3312-4971-b487-0335bb274703 | PubMed:26910225
  • Aghamohammadzadeh, R., Wylie, E., & Heagerty, A. (2015). Small vessel disease in CKD, diabetes, Obesity and hypertension. In Cardio-renal clinical challenges. Springer Verlag. . Publication link: 6a05078d-77d9-48d9-a17a-f51fb525fdda


  • Aghamohammadzadeh, R., Heagerty, A., Withers, S. B., Izzard, A., Greenstein, A., Mancia, G. (Ed.), ... Rendon, J. (Ed.) (2014). Small artery structure and function in hypertension. In Manual of Hypertension of the European Society of Hypertension. (2 ed.). CRC Press. . Publication link: 967da56a-b995-4921-b514-1ec40278fc0b
  • Yadav, R., France, M., Aghamohammadzadeh, R., Liu, Y., Hama, S., Kwok, S., ... Soran, H. (2014). HDL antioxidant function is impaired and adipose tissue inflammation is pronounced in obese patients with increasing severity of sleep apnea. e145. Abstract from 82nd EAS Congress, Madrid, .DOI: 10.1016/j.atherosclerosis.2014.05.409. Publication link: 1cd8db96-0e6f-4b2c-ae80-edb12a962ce7
  • Yadav, R., France, M., Aghamohammadzadeh, R., Liu, Y., Hama, S., Kwok, S., ... Soran, H. (2014). Impairment of high-density lipoprotein resistance to lipid peroxidation and adipose tissue inflammation in obesity complicated by obstructive sleep apnea. Journal of Clinical Endocrinology and Metabolism, 99(9), 3390-3398. DOI: 10.1210/jc.2013-3939. Publication link: ddfee45f-f379-4668-8e2b-82b2c779f6c1 | PubMed:24823455
  • Hand, L., Usan, P., Cooper, G. J. S., Xu, L. Y., Ammori, B., Cunningham, P., ... Ray, D. (2014). Adiponectin Induces A20 Expression in Adipose Tissue To Confer Metabolic Benefit.Diabetes, 64(Sep 4. pii: DB_131835. [Epub ahead of print]), 128-136. DOI: 10.2337/db13-1835, 10.2337/db13-1835. Publication link: edf6be87-1727-4b3b-9669-6f6446fbf176 | PubMed:25190567


  • Maron, B. A., Waxman, A. B., Opotowsky, A. R., Gillies, H., Blair, C., Aghamohammadzadeh, R., ... Leopold, J. A. (2013). Effectiveness of spironolactone plus ambrisentan for treatment of pulmonary arterial hypertension (from the [ARIES] Study 1 and 2 Trials). American Journal of Cardiology, 112(5), 720-725. DOI: 10.1016/j.amjcard.2013.04.051. Publication link: e74afdd2-21c3-4a3a-8b00-2f45c2b27f71
  • Aghamohammadzadeh, R., Loscalzo, J., Leopold, J. A., & Maron, B. A. (2013). Aldosterone targets Raptor to promote pulmonary smooth muscle cell proliferation and modulate pulmonary arterial hypertension. Circulation, 128(22). . Publication link: f4f242ce-e5a6-449c-9173-52d52a019c73
  • Aghamohammadzadeh, R., Greenstein, A., & Yadav, R. (2013). Effects of bariatric surgery on human small artery function: evidence for reduction in perivascular adipocyte inflammation, and restoration of normal anticontractile activity despite persistent obesity. The Lancet, 381. . Publication link: 2f3a876a-c502-4513-b624-507bc043effe
  • Aghamohammadzadeh, R., Greenstein, A., Yadav, R., Jeziorska, M., Hama, S., Soltani, F., ... Heagerty, A. (2013). Effects of Bariatric Surgery on Human Small Artery Function : Evidence for Reduction in Perivascular Adipocyte Inflammation, and the Restoration of Normal Anticontractile Activity Despite Persistent Obesity. Journal of American College of Cardiology, 62(2), 128-135. DOI: 10.1016/j.jacc.2013.04.027. Publication link: 8f3b1899-a9f7-404d-9d0b-98fad92df53e | PubMed:23665100
  • Aghamohammadzadeh, R., Heagerty, A., Loscalzo, J., Maron, B. A., & Leopold, J. A. (2013). Raptor activation by aldosterone promotes apoptosis resistance in pulmonary artery smooth muscle cells to modulate adverse pulmonary vascular remodeling in pulmonary arterial hypertension. FASEB J, 27. . Publication link: 9d771906-2339-4d3c-b26e-d1fc223602b2



  • Mastan, A., Bokhari, A., Aghamohammadzadeh, R., & Heagerty, A. M. (2011). A study of vitamin D levels and circulatory risk factors in primary care. Journal of Hypertension, 29. . Publication link: 6ee92695-914b-461d-8882-1320cb158560
  • Monfredi, O., Mastan, A., Aghamohammadzadeh, R., Egner, I., Boyett, M., & Heagerty, A. M. (2011). The effect of accelerated weight gain on blood pressure, intrinsic heart rate and the function of the cardiac conduction system. Journal of Hypertension, 29. . Publication link: 5f1a8321-e7ec-4d64-8509-3ec2f8393fc3
  • Aghamohammadzadeh, R., Gupta, S. K., Shen, C., Mather, K. J., Agarwal, R., & Dubé, M. P. (2011). Neither proteinuria nor albuminuria is associated with endothelial dysfunction in HIV-infected patients without diabetes or hypertension. In Journal of Infectious Diseases|J. Infect. Dis.. (1 ed., Vol. 204, pp. 1946-1950). Online: INTECH. DOI: 10.1093/infdis/jir668. Publication link: 01989350-49ec-45e8-9d61-4da834324690
  • Aghamohammadzadeh, R., Greentein, A., & Heagerty, A. M. (2011). Free radical scavengers rescue obesity-induced damage to the anticontractile property of perivascular adipose tissue in rat and human small arteries. Journal of Hypertension, 29. . Publication link: 009b67e4-9cb9-4d90-8b57-b692d3b52b19
  • Aghamohammadzadeh, R., Withers, S. B., Lynch, F. M., Greenstein, A. S., Malik, R., & Heagerty, A. M. (2011). Perivascular adipose tissue from human systemic and coronary vessels: The emergence of a new pharmacotherapeutic target. British Journal of Pharmacology, May 13. . Publication link: 096d915d-9cc0-4afd-ab5d-767cc67016da
  • Khavandi, K., Luckie, M., Aghamohammadzadeh, R., Khavandi, A., Mastan, A., Greenstein, A., ... Heagerty, A. M. (2011). Alterations in subcutaneous small artery wall structure correlate with diastolic parameters in patients with metabolic syndrome. Journal of the American College of Cardiology, 57(14). . Publication link: 44e2a68a-4586-454b-8cc3-56d3d9ae864f
  • Sonoyama, K., Greenstein, A. S., Micheletti, R., Ferrari, P., Schiavone, A., Aghamohammadzadeh, R., ... Heagerty, A. M. (2011). Mutation in the beta adducin subunit causes tissue-specific damage to myogenic tone. Journal of Hypertension, 29(3), 466-474. DOI: 10.1097/HJH.0b013e328341e1a1. Publication link: ddabf0c6-42bc-462d-ba0c-74bf18912683 | PubMed:21150638


  • Aghamohammadzadeh, R., Park, P. H., Greenstein, A. S., & Heagerty, A. M. (2010). Protection from development of obesity in high fat diet rats is associated with preservation of the anticontractile function of perivascular adipose tissue. Heart, 96. . Publication link: 442ffb2a-4575-4d09-98fc-b70b316cba98


  • Argyle, R. A., Beynon, R. P., Aghamohammadzadeh, R., Pearce, K. A., Borg, A. N., & Ray, S. G. (2009). Failure of the normal exercise induced enhancement of the left ventricular twist in patients with chronic mitral regurgitation and preserved ejection fraction. Heart, 95(23). . Publication link: befaedad-8112-4649-a965-5212e049fece
  • Aghamohammadzadeh, R., Argyle, R., & Ray, S. (2009). A patient with a large pericardial cyst. BMJ case reports. DOI: 10.1136/bcr.06.2008.0046. Publication link: bb793d72-f48b-4e5d-b43a-941ab2878fad
  • Beynon, R. P., Argyle, R. A., Aghamohammadzadeh, R., Pearce, K. A., Ray, S. G., & Davidson, N. C. (2009). A comparison of the haemodynamic benefit of atrioventricular and ventricular-ventricular biventricular pacemaker optimisation,Europace, 11. . Publication link: f345d72b-8643-4db2-969a-1ef3efebaf6a
  • Argyle, R., Beynon, R. P., & Aghamohammadzadeh, R. (2009). Left Ventricular twist on exercise deteriorates with increased volume overload in chronic mitral regurgitation. European Heart Journal, 30, 403. . Publication link: f32e70e6-3696-4590-8642-700c272ab19d
  • Argyle, R., Beynon, R. P., & Aghamohammadzadeh, R. (2009). Left ventricular untwisting on exercise is impaired in advanced chronic mitral regurgitation- a possible mechanism for exercise 11 intolerance. European Heart Journal, 30, 456. . Publication link: 510880ff-d6aa-4087-903f-c975d6a27513
  • Aghamohammadzadeh, R. (2009). Tea and cancer. Why northern Iran?British Medical Journal. . Publication link: 77918208-5534-4b18-a509-bfa99b93cb29


  • Hindocha, S., Thiryayi, W., Aghamohammadzadeh, R., & Madan, M. (2007). Patients’ perception of a doctor’s approach; evaluating opinion and influence of care. British Journal of Surgery, 94, 36. . Publication link: 8967ca65-44c1-4742-bfb9-045c9d1f52d5