MSc Tissue Engineering for Regenerative Medicine

Year of entry: 2021

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Course unit details:
Masterclass Course Unit

Unit code BIOL64101
Credit rating 15
Unit level FHEQ level 7 – master's degree or fourth year of an integrated master's degree
Teaching period(s) Semester 1
Offered by School of Biological Sciences
Available as a free choice unit? No

Overview

For students to obtain specialist knowledge of tissue engineering/regenerative medicine, they require a sufficient understanding of the general methodology and philosophy of research within these disciplines and its relationship to clinical therapy. To this end, the Masterclass unit will provide students with the principles of tissue engineering and regenerative medicine through a series of  combined seminars and discussion sessions with experts in the field. This unique teaching method aims to generate a multidisciplinary training environment and transfer knowledge in specialist areas.
 
The unit is delivered by academic and clinical-academic staff from across the Faculty of Biology, Medicine and Health, and Faculty of Science and Engineering to ensure a truly multidisciplinary approach. As seminars are delivered by staff members who are internationally recognised experts in their field, you will receive a state-of-the-art overview of new developments and emerging concepts and technologies in this rapidly developing field. Furthermore you have the opportunity to learn about research being carried out in the various Faculties and thereby apply a broad overview of different disciplines to your research. Students should participate in group discussion and will be encouraged to ask questions at the end of each seminar. Students are required to complete an on-line MCQ assessment and participate in a  group oral presentation.

The course will be run from September to December and usually involves four, one hour masterclasses per week.

Aims

The aims of the course unit are to:
  • provide the student with a detailed understanding of tissue engineering and regenerative medicine through a broad range of multidisciplinary topics,
  • develop in the student the ability to learn key facts and concepts after attending a verbal and/or audio-visual presentation and to assess the relevance of the work,
  • prepare students for a future career in tissue engineering by acquiring the knowledge and the skills to understand concepts, formulate ideas and translate these to clinical situations.

Learning outcomes

After completing the course unit, the student will:
  • have a broader understanding of the principles of tissue engineering and regenerative medicine and the methodology used,
  • have acquired the skills to learn new facts and concepts from an oral presentation, workshop, whilst at the same time discussing the specific topic in the broader context of tissue engineering,
  • merge, inter-relate and apply several research disciplines and technologies to address specific research problems leading to clear clinical outcomes

Teaching and learning methods

In most cases, students will receive two 1-hour lectures on the same subject area. The  first will provide an overview of the subject area, while the second will give specific examples of on-going research in the field. Students will be encouraged to discuss different aspects of the area covered and relate knowledge acquired with that from other modules to encourage multidisciplinary learning.

The course is split into four modules:

  1. Foundations of Biomaterials Design, Fabrication and Testing
  2. Tissue Structure, Repair and Regeneration
  3. Cell sourcing and characterisation
  4. From concept to clinic
 
The Masterclass may incorporate a laboratory visit to demonstrate a technique, piece of equipment or experimental model system, where appropriate. Presentations from each masterclass will be available on Blackboard as well as a list of relevant literature.

Assessment methods

Method Weight
Other 50%
Oral assessment/presentation 50%
  • multiple choice on-line assessment based on the information provided in masterclasses from Modules 1 and 2 (50% Assessment weighting). A maximum of 30 questions will form the assessment and students should choose the correct answer from 4 possible answers a to d. The assessment will be scheduled in October,/November further details to ensue. Students should complete the assessment in one sitting and will not be able to view other sites or return to the assessment at a later date.
  • team challenge consisting of a 15 minute group presentation (50% Assessment weighting) based on information provided in Modules 3-5. Each group (3 -5 students) is required to present an innovative solution to a major clinical problem using a tissue engineering/regenerative medicine approach. The assessment will be scheduled in December, further details to ensue.  Groups will be provided with a challenge and should arrange to meet beforehand to brainstorm ideas and practice showcasing their unique concept. Each group will deliver a PowerPoint presentation to the assessors and should be prepared to answer questions and discuss ideas.  Each team should prepare a maximum of 15 PowerPoint slides with each team member producing and presenting a maximum of 3-4 slides each.

Feedback methods

  • A blackboard questionnaire used to collect student opinion on the course unit,
  • Formal summative assessments with feedback,

Study hours

Scheduled activity hours
Lectures 2
Independent study hours
Independent study 150

Teaching staff

Staff member Role
Stephen Richardson Unit coordinator

Additional notes

The course is organised into 5 modules which cover the core issues that encompass tissue engineering and its application to regenerative medicine. These will mainly be in the format of a seminar or workshop. Modules 1 and 2 investigates the range of biomaterials available to the tissue engineer and their individual properties whereas module 3 will discuss normal repair processes resulting in scar formation and how embryos and certain species of adult animals are able to repair with complete regeneration. Module 4 covers the cellular aspects of tissue engineering in particular the application of stem cells whereas Module 5 details methodology to investigate engineered constructs through in vitro and in vivo modelling and the problems encountered when moving from the laboratory to the clinic.

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