MRes Experimental Medicine (Musculoskeletal)

Year of entry: 2019

Overview

Degree awarded
Master of Research
Duration
MRes 1 year FT, 36 months PT; PGCert 1 year PT
Entry requirements

We require an honours degree (minimum Upper Second) or overseas equivalent in:

  • biomedical sciences
  • medical sciences
  • life sciences
  • pharmaceutics
  • biotechnology
  • pharmacy
  • medicine
  • nursing
  • midwifery

This can be from any UK university or institution approved by The University of Manchester.

We also require you to hold existing qualifications to conduct clinical research as a General Medical Council-registered physician, Nursing and Midwifery Council-registered nurse or clinical trial coordinator, including evidence of current good clinical practice training.

Relevant experience and commitment to musculoskeletal research will be beneficial.

Full entry requirements

How to apply

Please apply via our online application form . See the application and selection section for details of the supporting documents we require.

We recommend that you apply as early as possible. We reserve the right to close applications if the course is full.

Course options

Full-time Part-time Full-time distance learning Part-time distance learning
MRes Y Y N N
PGCert N Y N N

Course overview

  • Develop the skills for a potential career that involves early phase clinical studies if you are a doctor, nurse, clinical researcher or research programme manager.
  • Spend a year working closely with the Experimental Medicine Musculoskeletal team of the Manchester Biomedical Research Centre while also taking four structured taught course units.
  • Open up careers in other experimental musculoskeletal medicine centres within the UK and EU, as well as careers in academia, the pharmaceutical industry and clinical trials management.
  • Study at a university ranked 9th in the UK for medicine (QS World University Rankings 2018).

Open days

Attending an open day is a great way to find out what studying at Manchester is like. Find out about our upcoming open days .

Fees

For entry in the academic year beginning September 2019, the tuition fees are as follows:

  • MRes (full-time)
    UK/EU students (per annum): £11,000
    International students (per annum): £24,000
  • MRes (part-time)
    UK/EU students (per annum): Year 1 £4,400, Year 2 £4,400, Year 3 £2,200
    International students (per annum): Year 1 £9,600, Year 2 £9600, Year 3 £4,800
  • PGCert (part-time)
    UK/EU students (per annum): £4,400
    International students (per annum): £9,600

The fees quoted above will be fully inclusive for the course tuition, administration and computational costs during your studies. All fees for entry will be subject to yearly review and incremental rises per annum are also likely. For general fees information please visit postgraduate fees .

Always contact the department if you are unsure which fee applies to your qualification award and method of attendance.

Policy on additional costs

All students should normally be able to complete their programme of study without incurring additional study costs over and above the tuition fee for that programme. Any unavoidable additional compulsory costs totalling more than 1% of the annual home undergraduate fee per annum, regardless of whether the programme in question is undergraduate or postgraduate taught, will be made clear to you at the point of application. Further information can be found in the University's Policy on additional costs incurred by students on undergraduate and postgraduate taught programmes (PDF document, 91KB).

Scholarships/sponsorships

Alumni bursary

The Faculty of Biology, Medicine and Health offers an alumni bursary of £1,000 towards tuition fees for successful applicants who are recent University of Manchester graduates and who are commencing one of our postgraduate taught master's programmes in 2019.

The bursary is available to students or alumni who:

  • graduated in 2018 or are graduating in 2019;
  • hold a first class honours degree;
  • have home or overseas fee status;
  • are applying for full- or part-time study;
  • are self-funded and not in receipt of any other funding support.

The bursary will be applied as a fee reduction automatically for those students and alumni who meet the alumni bursary criteria so there is no application process.

Contact details

School/Faculty
Faculty of Biology, Medicine and Health
Contact name
Postgraduate Admissions Team
Telephone
+44 (0)161 275 5220
Email
Website
https://www.bmh.manchester.ac.uk/medicine
School/Faculty
Faculty of Biology, Medicine and Health

Courses in related subject areas

Use the links below to view lists of courses in related subject areas.

Entry requirements

Academic entry qualification overview

We require an honours degree (minimum Upper Second) or overseas equivalent in:

  • biomedical sciences
  • medical sciences
  • life sciences
  • pharmaceutics
  • biotechnology
  • pharmacy
  • medicine
  • nursing
  • midwifery

This can be from any UK university or institution approved by The University of Manchester.

We also require you to hold existing qualifications to conduct clinical research as a General Medical Council-registered physician, Nursing and Midwifery Council-registered nurse or clinical trial coordinator, including evidence of current good clinical practice training.

Relevant experience and commitment to musculoskeletal research will be beneficial.

English language

International students must demonstrate English proficiency through a secure and approved testing system.

We ask for English language proof if you are from non-majority English speaking countries (a list of majority English speaking countries, as defined by the UK Home Office, can be found here ).

Specifically, we require a minimum of:

  • IELTS : 6.5 overall (6.5 in each component)
  • TOEFL: 90 internet-based (with 22 in each component)

See further information about requirements for your country .

We may also accept evidence of a confirmed place on a University Pre-sessional English language course , if your current IELTS scores are:

  • Minimum 6.0 overall with 6.0 in writing plus enrolment and attendance on the 6-week pre-sessional course (PS6)
  • Minimum 5.5 overall with 5.5 in writing plus enrolment and attendance on the 10-week pre-sessional course (PS10)

Please note, we must approve this before you apply for the English course.

English language test validity

Some English Language test results are only valid for two years. Your English Language test report must be valid on the start date of the course.

Relevant work experience

You need to be able to demonstrate relevant work experience in your chosen pathway.

Application and selection

How to apply

Please apply via our online application form . See the application and selection section for details of the supporting documents we require.

We recommend that you apply as early as possible. We reserve the right to close applications if the course is full.

Advice to applicants

Your application form must have the following documents:

  • two academic references on letter headed paper or sent from work emails. Professional references can be provided in instances where you have been out of university for more than 3 years. We do not contact referees directly;
  • official degree certificates (with translations if not in English);
  • official university transcripts (with translations if not in English);
  • a personal statement. This should be a page in length including: why you want to undertake this course of study; any relevant past experience and what you think you can bring to the course; how this course fits into your future career plans; any other information you think relevant to your application;
  • full curriculum vitae including voluntary experience;
  • a scanned copy of your passport if you require a Tier 4 visa to study in the UK;
  • if English is not your first language, we require proof of your English language ability. If you have already taken an English language qualification, please include your certificate with your application. We may be willing to consider your application without this document, but if we choose to make you an offer, the conditions will include IELTS (or equivalent qualification). 

Supporting documents can be uploaded with the online application form, or if this is not possible, emailed to pgtaught.medicine@manchester.ac.uk . We are unable to consider your application until we have received all of the documents listed above.

You must include your University ID number on any correspondence and do not send any documents before you have submitted your application.

Skills, knowledge, abilities, interests

You will need to have the ability to communicate well and work as part of a team.

Interview requirements

Applicants will need to attend an interview, either in person or via telephone/Skype.

Overseas (non-UK) applicants

Self-funded international applicants for this course will be required to pay a deposit of £1,000 towards their tuition fees before a confirmation of acceptance for studies (CAS) is issued. This deposit will only be refunded if immigration permission is refused. We will notify you about how and when to make this payment.

Please upload a copy of your current valid passport with your application showing the photograph page with your application. For CAS purposes, this must show your full name, date of birth, nationality, passport number and the date the passport is valid until, which must be later than the date of your planned arrival in the UK, and the start date of your course.

You cannot use your CAS to apply for a visa more than three months before the start date of your course. This means that if you intend to begin a course on 16 September 2019, we will not issue you with a CAS number before 16 June 2019.

Your CAS number is only valid for one Tier 4 application.

Fitness to practise / health requirements

All physician applicants need to provide their GMC number. All nurse applicants need to provide their NMC number.

Disclosure and Barring Service check

For clinical placements a Disclosure and Barring Service check (DBS) check will be require for UK residents. Overseas students are required to provide a Police/Government Office Certificate of Good Conduct.

Please email pgtaught.medicine@manchester.ac.uk for further guidance.

Deferrals

No deferrals will be considered.

Course details

Course description

Our MRes Experimental Medicine (Musculoskeletal) programme will give nurses, doctors, clinical researchers and research programme managers the skills needed to work in early phase clinical studies.

You will learn how to master experimental medicine with a focus on musculoskeletal through a combination of traditional teaching and hands-on learning that includes spending a year working closely with the Experimental Medicine Musculoskeletal Team of the Biomedical Research Centre while also taking four structured taught units.

The taught units will see you learn the details of designing and delivering Phase 1 clinical studies, understanding the pre-clinical data required before a clinical programme can commence, and how to optimise early clinical studies to provide evidence for progressing a promising drug or intervention into Phase II/III clinical testing.

Alongside the taught elements, you will have a named supervisor and be exposed to tasks required in the setup, delivery, interpretation and audit of a clinical study.

Nursing and physician students may participate in patient care, including new and follow-on patient clinics, treatment and care-giving episodes with patients.

For non-registered clinical researchers and research programme managers, no direct patient contact is envisaged and you may participate in clinical trial setup, protocol amendments, database setup, data entry, costing and billing for clinical research.

You will be able to choose two aspects of your direct clinical trial research experience to write up for your two research projects in a dissertation format. This will give you the skills and knowledge required to critically report medical, scientific and clinically related sciences for peer review.

Aims

The primary purpose of the MRes in Experimental Medicine (Musculoskeletal) is to provide you with the opportunity to work within a premier Biomedical Research Centre and, through a mix of taught and experiential learning, master the discipline of experimental medicine related to musculoskeletal.

Special features

Extensive practical experience

You will spend most of your time gaining hands-on experience through completion of two research projects working closely with the Experimental Medicine Musculoskeletal Team of the Manchester Biomedical Research Centre

Taught by experts in Experimental Medicine within dedicated research and clinical trials facilities

You will also have opportunities to interact with and learn from experimental medicine researchers across a range of different fields within the Manchester Biomedical Research Centre and the Manchester Clinical Research Facility and thereby broaden your knowledge and experience of experimental medicine.

Additional course information

Meet the course team

Dr Ben Parker (Musculoskeletal Pathway Lead)

Dr Ben Parker is a Consultant Rheumatologist at Manchester Royal Infirmary and Honorary Senior lecturer at University Of Manchester. Dr Parker is Medical Director Manchester (Adult) Clinical Research Facility at Central Manchester and training lead for the NIHR Manchester CRF, in addition to his role in Manchester BRC MSK theme. His research and clinical interests are in the outcomes and management of systemic lupus erythematosus, and he is Principal Investigator on several early and later phase clinical trials in SLE and related diseases.

Professor Anne Barton

Professor Anne Barton is a Professor of Rheumatology at University of Manchester and Honorary Consultant Rheumatologist at Manchester Royal Infirmary. Professor Barton is Theme Lead for MSK in the Manchester BRC. She has a program of work in pharmacogenetics, particularly in predicting response to treatment in patients receiving biologic therapies for their arthritic diseases. She has a strong interest in the genetic predisposition to psoriatic arthritis, the second most common of the inflammatory arthritic diseases.

Teaching and learning

Our course is structured around a 2:1 split between clinical-based research projects and taught elements respectively.

Taught course units will predominantly use lectures and workshops.

For the research projects, teaching and learning will take place through one-to-one mentoring from a member of the Experimental Medicine Musculoskeletal team.

The clinical and academic experience of contributors to this course will provide you with an exceptional teaching and learning experience.

Coursework and assessment

You will be assessed through oral presentations, single best answer exams, written reports and dissertation.

For each research project, you will write a dissertation of 10,000 to 15,000 words. Examples of suitable practical projects include the following.

Research proposal

  • Compilation of a research proposal to research council/charity
  • Writing a protocol and trial costings for sponsor
  • Research and write a successful expression of interest selected by grant funder for full development

Publication-based/dissertation by publication

  • Writing a clinical study report
  • Authoring a peer-review journal review/original article

Service development/professional report/ report based dissertation

  • Public health report/outbreak report/health needs assessment/health impact assessment
  • Proposal for service development/organisational change
  • Audit/evaluate service delivery/policy
  • Implement recommended change from audit report

Adapted systematic review (qualitative data)

  • Compiling the platform of scientific evidence for a new drug indication from literature
  • Review of alternative research methodologies from literature

Full systematic review that includes data collection (quantitative data)

  • Referral patterns for Phase 1 patients

Qualitative or quantitative empirical research

  • Design, conduct, analyse and report an experiment

Qualitative secondary data analysis/analysis of existing quantitative data

  • Compilation, mining and analysis of existing clinical data sets

Quantitative secondary data analysis/analysis of existing qualitative data/theoretical study/narrative review

  • Policy analysis or discourse analysis/content analysis
  • A critical review of policy using framework analysis

Course unit details

This course consists of four taught 15-credit units and two practical 60-credit research projects. Students achieving 180 credits will be awarded the MRes; students may receive a PGDip in Experimental Medicine (Musculoskeletal) upon achievement of 120 credits. There is also an option for students to register for a PGCert and complete only the four taught units on a part-time basis for 60 credits.

The four taught units run as follows:

  • Research Methods (October)
  • Introduction to Experimental Medicine (November/December)
  • Assembling Pre-clinical and Early Clinical Development Strategies for a new Candidate Drug (February/March)
  • Designing a Translational Medicine Strategy for a Clinical therapy or Intervention (June)

Please see the course unit list below for more information on each unit and project.

Course unit list

The course unit details given below are subject to change, and are the latest example of the curriculum available on this course of study.

TitleCodeCredit ratingMandatory/optional
Laboratory Skills Unit MEDN66111 15 Mandatory
Assembling preclinical and translational medicine strategies for a new candidate drug MEDN66212 15 Mandatory
Research Project 1 MEDN66230 60 Mandatory
Research Project 2 MEDN66242 60 Mandatory
Introduction to Experimental Medicine MEDN69631 15 Mandatory
Designing a translational medicine strategy for a clinical intervention MEDN69632 15 Mandatory
Research Methods MEDN69910 15 Mandatory

Facilities

Teaching will take place within The Christie NHS Foundation Trust, the Manchester Clinical Research Facility and The University of Manchester Campus. Projects may be conducted within one of the Biomedical Research Centre affiliated NHS Trusts.

Disability support

Practical support and advice for current students and applicants is available from the Disability Advisory and Support Service .

Careers

Career opportunities

This course is relevant to physician, nursing and clinical researchers and research programme managers who are considering careers that involve Phase 1 clinical studies.

The course provides theoretical and experiential learning and offers a foundation for roles within other experimental medicine centres within the UK and EU, as well as careers in academia, the pharmaceutical industry and clinical trials management.

The MRes is ideal for high-calibre graduates and professionals wishing to undertake research training in the field of musculoskeletal medicine.