BSc Biotechnology / Course details

Year of entry: 2020

Course unit details:
Molecules and Cells in Human Disease

Unit code BIOL21351
Credit rating 10
Unit level Level 2
Teaching period(s) Semester 1
Offered by School of Biological Sciences
Available as a free choice unit? No

Overview

You will learn about the basic cellular mechanisms underlying common human diseases and understand how drugs act on cellular and tissue dysfunctions to treat these diseases. You will study topics including autoimmune disease, cancer and arthritis.

Pre/co-requisites

Unit title Unit code Requirement type Description
From Molecules to Cells BIOL10232 Pre-Requisite Recommended
Drugs: From Molecules to Man BIOL10822 Pre-Requisite Recommended

Aims

To introduce cellular and molecular mechanisms of human disease.

Learning outcomes

Students will acquire knowledge of the basic cellular mechanisms underlying common human diseases and will understand how drugs act on cellular and tissue dysfunctions to ameliorate these diseases.

Syllabus

The course examines the cellular and molecular causes of a wide variety of human diseases such as diabetes and cancer. It aims to show how understanding a disease at the molecular level explains its pathology and allows the design of therapeutic strategies. Specific topics will include:

  • Cell death mechanisms and disease
  • Cell adhesion and its pathological defects of connective tissues
  • Type 1 and 2 diabetes
  • Biochemical complications of diabetes and therapies
  • Inflammation and anti-inflammatory drugs
  • Molecular pathology of cancer
  • Cancer chemotherapy

eLearning Activity

Each set of lectures will be followed by an online quiz to provide formative feedback on your understanding of the material

A graphical exercise on diabetes will be provided on Blackboard. This includes example essay and short answer questions on the subject of diabetes and its pharmacology.

Employability skills

Research
Students have to carry out additional reading for each lecture.
Other
Meeting multiple deadlines. Students have a number of on line activities to completes, with fixed deadlines. Students have to manage these deadlines.

Assessment methods

Method Weight
Other 10%
Written exam 90%

2 hour written Exam worth 90% of the final unit mark, comprising short answer questions (40% of exam) and 1 essay (60% of exam).

eLearning activities worth 10% of the final unit mark.

Feedback methods

The eLearning activities will provide on line feedback. Advice on the example exam questions on the eLearning resource will be provided if requested. Feedback will be given on the MCQ assessment before the end of the course. Post-exam guidance will be provided.

A formative mid-semester miniexam

A formative mock exam

Recommended reading

The following general texts will provide useful background include. However, no one textbook will cover all the material presented in the lectures, due to the diverse nature of the course. Each lecturer will therefore provide specific reference articles for their lecture material.

Recommended Reading

  1. Alberts B, Johnson A, Lewis J, Raff M, Roberts K & Walter P, Molecular Biology of the Cell (6th edition), Garland Science, 2015, Recommended
  2. Cassimeris, Lingappa, Plopper, Lewin's Cells (3rd edition), Jones and Bartlett, Recommended
  3. Rang HP, Ritter JM & Flower, R, and Henderson Rang & Dale's Pharmacology (8th Edition), Elsevier, Recommended

Study hours

Scheduled activity hours
Assessment written exam 2
Lectures 22
Independent study hours
Independent study 76

Teaching staff

Staff member Role
Andrew Gilmore Unit coordinator

Return to course details