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Autism: recent molecular genetic advances
Lamb J, MooreJ, BaileyA, MonacoA.P
Hum. Mol. Genet. 2000;9(6):861-868.
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Abstract
Autism (MIM 209850) is a severe neuropsychiatric disorder of unknown aetiology with profound consequences for patients and their families. Strong evidence from twin and family studies indicates the importance of genetic factors in the development of idiopathic autism, although it is clear that these influences are complex. This review focuses on recent molecular investigations to identify susceptibility loci implicated in autistic disorder
Keyword(s)
Autistic Disorder; Chromosome Aberrations; Chromosome Disorders; Genetic Predisposition to Disease; Humans; Linkage (Genetics); genetics
Bibliographic metadata
- DA - 20000531IS - 0964-6906 (Print)LA - engPT - Journal ArticlePT - Research Support, Non-U.S. Gov'tPT - ReviewSB - IM