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The potential of pharmacogenetics in optimizing the use of methotrexate for psoriasis.

Warren, R B; Griffiths, C E M

The British journal of dermatology. 2005;153(5):869-73.

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Abstract

The study of pharmacogenetics will optimize the use of systemic therapies in dermatology. Directed prescription of azathioprine dependent on phenotypic expression of the thiopurine methyltransferase gene is now accepted practice. To some extent other, older drugs have been neglected. We look at the role that pharmacogenetics could play in the use of methotrexate for psoriasis, focusing on known polymorphisms in the folate metabolic pathway.

Bibliographic metadata

Content type:
Published date:
Language:
eng
Abbreviated journal title:
ISSN:
Place of publication:
England
Volume:
153
Issue:
5
Pagination:
869-73
Digital Object Identifier:
10.1111/j.1365-2133.2005.06880.x
Pubmed Identifier:
16225593
Pii Identifier:
BJD6880
Access state:
Active

Institutional metadata

University researcher(s):

Record metadata

Manchester eScholar ID:
uk-ac-man-scw:79541
Created by:
Warren, Richard
Created:
24th April, 2010, 20:06:30
Last modified by:
Warren, Richard
Last modified:
24th April, 2010, 20:06:30

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