Dr Jonathan Humphries (BSc, MSc, PhD) - publications

Unknown

• Humphries, J., Byron, A., Bass, M., Craig, S., Pinney, J., Knight, D. & Humphries, M Proteomic analysis of integrin-associated complexes identifies RCC2 as a dual regulator of Rac1 and Arf6. Sci Signal, 2(87), ra51. eScholarID:75048 | PMID:19738201 | DOI:10.1126/scisignal.2000396

2009

• Byron, A., Humphries, J., Askari, J., Craig, S., Mould, A. & Humphries, M (2009). Anti-integrin monoclonal antibodies. J Cell Sci, 122(Pt 22), 4009-11. eScholarID:75496 | PMID:19910492 | DOI:10.1242/jcs.056770
• Humphries, J., Byron, A., Bass, M., Craig, S., Pinney, J., Knight, D. & Humphries, M (2009). Proteomic analysis of integrin-associated complexes identifies RCC2 as a dual regulator of Rac1 and Arf6. Sci Signal, 2(87), ra51. eScholarID:56821 | PMID:19738201 | DOI:10.1126/scisignal.2000396
• Humphries, J., Byron, A., Bass, M., Craig, S., Pinney, J., Knight, D. & Humphries, M (2009). Proteomic analysis of integrin-associated complexes identifies RCC2 as a dual regulator of Rac1 and Arf6. Sci Signal, 2(87), ra51. eScholarID:56807 | PMID:19738201 | DOI:10.1126/scisignal.2000396

2008

• Parsons, M., Messent, A., Humphries, J., Deakin, N. & Humphries, M (2008). Quantification of integrin receptor agonism by fluorescence lifetime imaging. J Cell Sci, 121(Pt 3), 265-71. eScholarID:56822 | PMID:18216331 | DOI:10.1242/jcs.018440
• Parsons, M., Messent, A., Humphries, J., Deakin, N. & Humphries, M (2008). Quantification of integrin receptor agonism by fluorescence lifetime imaging. J Cell Sci, 121(Pt 3), 265-71. eScholarID:56808 | PMID:18216331 | DOI:10.1242/jcs.018440

2007

• Askari, J., Thornton, D., Humphries, J., Buckley, P. & Humphries, M (2007). The alternatively spliced type III connecting segment of fibronectin is a zinc-binding module. Matrix Biol, 26(6), 485-93. eScholarID:56825 | PMID:17490871 | DOI:10.1016/j.matbio.2007.04.001
• Askari, J., Thornton, D., Humphries, J., Buckley, P. & Humphries, M (2007). The alternatively spliced type III connecting segment of fibronectin is a zinc-binding module. Matrix Biol, 26(6), 485-93. eScholarID:56810 | PMID:17490871 | DOI:10.1016/j.matbio.2007.04.001
• Humphries, J. & Humphries, M (2007). CD14 is a ligand for the integrin alpha4beta1. FEBS Lett, 581(4), 757-63. eScholarID:56826 | PMID:17274987 | DOI:10.1016/j.febslet.2007.01.038
• Humphries, J. & Humphries, M (2007). CD14 is a ligand for the integrin alpha4beta1. FEBS Lett, 581(4), 757-63. eScholarID:56811 | PMID:17274987 | DOI:10.1016/j.febslet.2007.01.038
• Humphries, J., Wang, P., Streuli, C., Geiger, B., Humphries, M. & Ballestrem, C (2007). Vinculin controls focal adhesion formation by direct interactions with talin and actin. J Cell Biol, 179(5), 1043-57. eScholarID:56823 | PMID:18056416 | DOI:10.1083/jcb.200703036
• Humphries, J., Wang, P., Streuli, C., Geiger, B., Humphries, M. & Ballestrem, C (2007). Vinculin controls focal adhesion formation by direct interactions with talin and actin. J Cell Biol, 179(5), 1043-57. eScholarID:56809 | PMID:18056416 | DOI:10.1083/jcb.200703036

2006

• Humphries, J., Byron, A. & Humphries, M (2006). Integrin ligands at a glance. J Cell Sci, 119(Pt 19), 3901-3. eScholarID:56827 | PMID:16988024 | DOI:10.1242/jcs.03098
• Humphries, J., Byron, A. & Humphries, M (2006). Integrin ligands at a glance. J Cell Sci, 119(Pt 19), 3901-3. eScholarID:56812 | PMID:16988024 | DOI:10.1242/jcs.03098

2005

• Gläsner, J., Blum, H., Wehner, V., Stilz, H., Humphries, J., Curley, G., Mould, A., Humphries, M., Hallmann, R., Röllinghoff, M. & Gessner, A (2005). A small molecule alpha 4 beta 1 antagonist prevents development of murine Lyme arthritis without affecting protective immunity. J Immunol, 175(7), 4724-34. eScholarID:56829 | PMID:16177120
• Gläsner, J., Blum, H., Wehner, V., Stilz, H., Humphries, J., Curley, G., Mould, A., Humphries, M., Hallmann, R., Röllinghoff, M. & Gessner, A (2005). A small molecule alpha 4 beta 1 antagonist prevents development of murine Lyme arthritis without affecting protective immunity. J Immunol, 175(7), 4724-34. eScholarID:56813 | PMID:16177120
• Humphries, J., Schofield, N., Mostafavi-Pour, Z., Green, L., Garratt, A., Mould, A. & Humphries, M (2005). Dual functionality of the anti-beta1 integrin antibody, 12G10, exemplifies agonistic signalling from the ligand binding pocket of integrin adhesion receptors. J Biol Chem, 280(11), 10234-43. eScholarID:56830 | PMID:15632175 | DOI:10.1074/jbc.M411102200
• Humphries, J., Schofield, N., Mostafavi-Pour, Z., Green, L., Garratt, A., Mould, A. & Humphries, M (2005). Dual functionality of the anti-beta1 integrin antibody, 12G10, exemplifies agonistic signalling from the ligand binding pocket of integrin adhesion receptors. J Biol Chem, 280(11), 10234-43. eScholarID:56814 | PMID:15632175 | DOI:10.1074/jbc.M411102200

2003

• Bax, D., Bernard, S., Lomas, A., Morgan, A., Humphries, J., Shuttleworth, C., Humphries, M. & Kielty, C (2003). Cell adhesion to fibrillin-1 molecules and microfibrils is mediated by alpha 5 beta 1 and alpha v beta 3 integrins. J Biol Chem, 278(36), 34605-16. eScholarID:75590 | PMID:12807887 | DOI:10.1074/jbc.M303159200
• Travis, M., Humphries, J. & Humphries, M (2003). An unraveling tale of how integrins are activated from within. Trends Pharmacol Sci, 24(4), 192-7. eScholarID:56831 | PMID:12707006
• Travis, M., Humphries, J. & Humphries, M (2003). An unraveling tale of how integrins are activated from within. Trends Pharmacol Sci, 24(4), 192-7. eScholarID:56815 | PMID:12707006

2000

• Humphries, J., Askari, J., Zhang, X., Takada, Y., Humphries, M. & Mould, A (2000). Molecular basis of ligand recognition by integrin alpha5beta 1. II. Specificity of arg-gly-Asp binding is determined by Trp157 OF THE alpha subunit. J Biol Chem, 275(27), 20337-45. eScholarID:56832 | PMID:10764747 | DOI:10.1074/jbc.M000568200
• Humphries, J., Askari, J., Zhang, X., Takada, Y., Humphries, M. & Mould, A (2000). Molecular basis of ligand recognition by integrin alpha5beta 1. II. Specificity of arg-gly-Asp binding is determined by Trp157 OF THE alpha subunit. J Biol Chem, 275(27), 20337-45. eScholarID:56816 | PMID:10764747 | DOI:10.1074/jbc.M000568200

1998

• Griffiths, C., Ancian, P., Humphries, J., Poncet, M., Rizova, E., Michel, S. & Clucas, A (1998). Adapalene 0.1% gel and adapalene 0.1% cream stimulate retinoic acid receptor mediated gene transcription without significant irritative effects in the skin of healthy human volunteers. Br J Dermatol, 139 Suppl 52, 12-6. eScholarID:75591 | PMID:9990415
• Humphries, J., Parry, E., Watson, R., Garrod, D. & Griffiths, C (1998). All-trans retinoic acid compromises desmosome expression in human epidermis. Br J Dermatol, 139(4), 577-84. eScholarID:56833 | PMID:9892899
• Humphries, J., Parry, E., Watson, R., Garrod, D. & Griffiths, C (1998). All-trans retinoic acid compromises desmosome expression in human epidermis. Br J Dermatol, 139(4), 577-84. eScholarID:56818 | PMID:9892899
• Watson, R., Parry, E., Humphries, J., Jones, C., Polson, D., Kielty, C. & Griffiths, C (1998). Fibrillin microfibrils are reduced in skin exhibiting striae distensae. Br J Dermatol, 138(6), 931-7. eScholarID:56835 | PMID:9747352
• Watson, R., Parry, E., Humphries, J., Jones, C., Polson, D., Kielty, C. & Griffiths, C (1998). Fibrillin microfibrils are reduced in skin exhibiting striae distensae. Br J Dermatol, 138(6), 931-7. eScholarID:56820 | PMID:9747352

1995

• Whitehurst ,C. , Humphries , J.D. , Moore , J.V. (1995). Development of an alternative light source to lasers for photodynamic therapy: 2. Comparative in-vivo tumour response characteristics. Lasers In Medical Science, 10, 121-126. eScholarID:75592