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Dr Julie Andrews (PhD, BSc, MI Biol) - publications

List of publications


  • Newman, W. G., Payne, K., Tricker, K., Roberts, S. A., Fargher, E., Pushpakom, S., ... Ollier, W. E. R. (2011). A pragmatic randomized controlled trial of thiopurine methyltransferase genotyping prior to azathioprine treatment: The TARGET study. Pharmacogenomics, 12(6), 815-826. DOI: 10.2217/pgs.11.32. Publication link: 123db8fa-3bbf-4420-bfe7-57001a3883d3 | PubMed:21692613


  • Hakooz, N., Arafat, T., Payne, D., Ollier, W., Pushpakom, S., Andrews, J., & Newman, W. (2010). Genetic analysis of thiopurine methyltransferase polymorphism in the Jordanian population. European Journal of Clinical Pharmacology, 66(10), 999-1003. DOI: 10.1007/s00228-010-0826-1. Publication link: d61c00d4-d0da-4eaa-9304-7ffb2542f078 | PubMed:20521035



  • Hasnat, A., Bichenkova, E., Yu, X., Arnold, J. R. P., Fisher, J., Fedorova, O., & Andrews, J. (2007). Fluorescence spectroscopic and 19F NMR studies of human thymidylate synthase with its cognate RNA. Journal of Biomolecular Structure and Dynamics, 25(3), 253-269. DOI: 10.1080/07391102.2007.10507174. Publication link: 11faa174-b914-4fd6-99a3-cd9964868d38


  • Payne, K., Fargher, E. A., Tricker, K., Newman, W. G., Qasim, F. F., Poulton, K., ... Ollier, W. E. R. (2005). Research Governance: What is reasonable protection?BMJ Rapid Response. . Publication link: 4d5e6536-3b55-4349-8e15-e246d4049646
  • Newman, W. G., Payne, K., Poulton, K., Andrews, J., Houston, B., Elliott, R. A., ... Ollier, W. E. R. (2005). The TARGET (TPMT: Azathioprine Response to Genotyping and Enzyme Testing) study. BMJ. . Publication link: eeecaedb-25ac-48d6-b685-e3098e71999e


  • Andrews, J., Pasksaleva, E., Galetin, A., & Houston, B. (2003). Pharmacogencomics and predictive drug metabolism. In Pharmacogencomics and predictive drug metabolism. Pharmacogenomics Workshop, Annual Human Genome Meeting, Cancun, Mexico.. Publication link: 8d747955-b93c-4238-ab15-ad85688f31af


  • Andrews, J., Abd-Ellah, M. F., Randolph, N. L., Kenworthy, K. E., Carlile, D. J., Friedberg, T., & Houston, J. B. (2002). Comparative study of the metabolism of drug substrates by human cytochrome P450 3A4 expressed in bacterial, yeast and human lymphoblastoid cells. Xenobiotica, 32(11), 937-947. DOI: 10.1080/00498250210163289. Publication link: d90d5c5a-737a-4a7c-9884-7c6a7341a9d1


  • Peng, B., Andrews, J., Nestorov, I., Brennan, B., Nicklin, P., & Rowland, M. (2001). Tissue distribution and physiologically based pharmacokinetics of antisense phosphorothioate oligonucleotide ISIS 1082 in rat. Antisense and Nucleic Acid Drug Development, 11(1), 15-27. DOI: 10.1089/108729001750072092. Publication link: 7731a9fa-443c-4bae-8c88-acf2912669fc
  • Kenworthy, K. E., Clarke, S. E., Andrews, J., & Houston, J. B. (2001). Multisite kinetic models for CYP3A4: Simultaneous activation and inhibition of diazepam and testosterone metabolism. Drug Metabolism and Disposition, 29(12), 1644-1651. . Publication link: 7f058472-991c-4f41-8677-8dad0de5c034


  • Andrews, J., Allison, D. G., & Gilbert, P. (1999). Staphylococcal alkaline shock protein (Asp23) is expressed at neutral pH in Staphylococcus aureus biofilms. In Proceedings of the 99th Annual General Meeting of the American Society for Microbiology, Chicago, Il., May.. Publication link: a38022a5-fa60-494e-a5d4-c1cca3f553e9


  • Hamilton, B. J., & Andrews, J. (1998). Expression and characterization of the E. coli mismatch repair enzyme MutH. In Cold Spring Harbour Symposium, N.Y. Aug 98.. Publication link: d8a26c73-b47c-48d8-9274-e2bb56d537d0
  • Kenworthy, K. K. E., Clarke, S. E., Andrews, J., & Houston, B. (1998). Sigmoidal kinetics of CYP3A4: the simultaneous metabolism and binding of testosterone and diazepam. In Br. J. Clin. Pharmacol.. (Vol. 45). Publication link: 2ff16944-ad53-4b4b-8671-5801531f2d18
  • Courtney, R. D., Nicklin, P. L., Philips, J. A., Andrews, J., & Rowland, M. (1998). Influence of protein binding on hepatic distribution kinetics of antisense oligonucleotides.Europ. J. Pharm. Sci., 6. . Publication link: 3b4925e3-5e8c-4911-8aeb-664d7fd313ca
  • Kenworthy, K. K. E., Clarke, S. E., Andrews, J., & Houston, B. (1998). The simultaneous metabolism and binding of testosterone and diazepam in a recombinant CYP3A4 enzyme system. At 12th International Symposium on Microsomes and Drug Oxidations, Montpellier, France. In Proceedings.. Publication link: 22908e2b-cf9c-408e-a2ea-99cbd403c194
  • Montgomery, H., Gaskell, S. J., Hodgson, A. E., Andrews, J., & Gilbert, P. (1998). Staphylococcal Alkaline Shock Protein (asp23) is expressed at neutral pH in Staphylococcus aureus biofilms.FEMS Letters. . Publication link: 8b5fe53f-fe69-4607-8940-9f41ba545a2b
  • Courtney, R. D., Nicklin, P. L., Phillips, J. A., Andrews, J., & Rowland, M. (1998). The hepatocellular binding of a phosphorothioate (P=S) antisense oligonucleotide, ISIS 1082. In Antisense 1998, London Oct 98.. Publication link: 5e35d5cb-246c-40ea-a33c-364a4a1ef54a


  • Courtney, R. D., Nicklin, P. L., Phillips, J. A., Andrews, J., & Rowland, M. (1997). Effect of perfusate protein on the hepatic distribution of a phosphorothioate antisense oligonucleotide. In Antisense Oligonucleotides, Cambridge Sept 97... Publication link: ce4c9325-07e7-42f5-b86e-414f6db04d1c
  • Wyber, J. A., Andrews, J., & D'Emanuele, A. (1997). The use of sonication for the efficient delivery of plasmid DNA into cells. Pharmaceutical Research, 14(6), 750-756. . Publication link: 9946123e-7771-445b-8087-42b5d3abab27
  • Hamilton, B. J., Hynes, C. G., & Andrews, J. (1997). Expression and purification of the E. coli DNA repair protein mut-H. Biochemical Society Transactions, 25(1), 137. . Publication link: 560121a5-531b-426f-b272-6e1059b16d9e


  • Randolph, N., Andrews, J., Chenery, R., & Houston, B. (1996). Metabolism of midazolam in various expression systems for human CYP3A4. In 6th Stowe Symposium, Stoke Rochford.. Publication link: 66b08e3a-5651-4cf4-8773-3de582682ed6
  • Wilton, A. N., Andrews, J., Douglas, K. T., Sadat-Ebrahimi, S., & Parkinson, J. A. (1996). Rational Design of a New Class of DNA Cleaver Based on Prediction of Minor Groove Binding Interactions and NMR Structural Studies. In B. Meunier (ed.), DNA and RNA Cleavers and Chemotherapy of Cancer and Viral Diseases. Kluwer Academic Publ. . Publication link: 4c9cb9fc-f262-48f4-abb6-b445f357999d


  • Andrews, J., Clore, G. M., Davies, R. W., Gronenborn, A. M., Gronenborn, B., Kalderon, D., ... Stancombe, R. (1985). Nucleotide sequence of the dihydrofolate reductase gene of methotrexate-resistant Lactobacillus casei. Gene, 35(1-2), 217-222. DOI: 10.1016/0378-1119(85)90174-X. Publication link: 7c877697-4e3f-4f88-a460-a49f799e2c66
  • Sims, P. F. G., Minter, S. J., Stancombe, R., Gent, M. E., Andrews, J., Waring, R. B., ... Davies, R. W. (1985). A modified two primer approach to oligonucleotide-directed in vitro mutagenesis. Biochimie, 67(7-8), 841-847. DOI: 10.1016/S0300-9084(85)80177-2. Publication link: b45cd338-41ae-4485-8eb4-3cc60b018452