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Professor Ludwig Neyses - personal details

Contact details

Professor Ludwig Neyses

Role: Professor of Medicine/Cardiology

Tel: +44 (0)161 275 1628

Location:

Institute of Cardiovascular Sciences

Stopford Building 1.302

Oxford Road

M13 9PL

Manchester

Websites

 

Biography

  • Present position: Vice President for Research, University of Luxembourg, joint appointment with Manchester (since 04/2013)
  • Chair of Medicine/Cardiology, University of Manchester (since 08/2001), age 58
  • Medical School training in Mainz, Germany, Montpellier, France (4th year), and Westminster Medical School, London (final year). German and US qualifying final exam (VQE, Visa qualifying exam for US) in 1979
  • Training in Internal Medicine and Cardiology at the University Hospitals of Zurich, Switzerland, and Bonn, Germany. Training in special interventional techniques at Beaumont Hospital, Royal Oak, Michigan, USA
  • Assistant Professor of Medicine in 1991
  • 1994 – 07/2001 Associate Professor of Medicine, University Hospital of Wuerzburg, Germany (Internal Medicine, subspecialty: cardiology). Attending physician for both cardiological and general medical patients and interventional activities in the catheterisation laboratory as well as scientific work
  • Scientific training with M.P. Dierich, Institute of Immunology, Mainz, Germany (MD thesis on complement receptors), W. Siegenthaler and W. Vetter, Dep. of Medicine, University Hospital, Zurich, Switzerland (molecular mechanisms of hypertensive heart disease and early atherosclerosis), E. Carafoli, Institute of Biochemistry, Federal Institute of Technology, Zurich, Switzerland (calcium transport in the heart), and R.S. Williams, Cardiovascular Division, Dep. of Medicine, Duke University, Durham, NC (molecular biology of signal transduction in cardiac hypertrophy and failure).
  • 167 Papers with emphasis on the clinical aspects and molecular biology of cardiac hypertrophy and failure, especially signal transduction, calcium transport, and the action of estrogens (and derivatives) on the heart.
  • Grants:
  • 2011-2016 A novel role for the plasma membrane calcium pump PMCA1 in cardiomyopathy and blood pressure control. £1.25 million Medical Research Council awarded in April 2011. Grant Ref G1002082
  • 2010-2013 The sarcolemmal calcium signalling protein PMCA4 as a novel target to reduce cardiac hypertrophy and failure. £600k Medical Research Council awarded September 2009. Grant Ref G802004.
  • 2009 Identification and evaluation of novel serum biomarkers for heart failure using metabolomics - an initial step towards a holistic view of heart failure. £58,000 Biomedical Research Centre, Central Manchester University Hospital Foundation Trust.
  • 2006-2009 Integrative physiology of the plasma membrane calcium pump isoform 4 in the healthy and failing heart. £900k Programme grant from the Medical Research Council. Grant Ref G500025.
    I am the cardiovascular lead for an EU-wide phenotyping programme for systematic knock-out of 650 genes (EUMODIC, 12 million Euros) and was involved in its predecessor programme, EUMORPHIA (9million Euros). 10 projects grants, industrial collaborations etc. in the last 5 years.
  • ‘Special Research Centre’, German Research Association (1994-2005, co-organiser) (5 million Euros); International Appointee Grant, MRC, UK, 2002-5 (£1 million); Programme Grant, MRC, 2006-9 (900k£).

Memberships of Committees and Professional Bodies

Membership of Professional Bodies
 
  • Elected Fellow, Society of Biology
  • Scientific Council of the American Heart Association
  • British Cardiovascular Society
  • British Biochemical Society
  • Working Group on Hypertension and the Heart of the European Society of Cardiology
  • Working Group on Cellular Biology of the European Society of Cardiology
  • German Cardiac Society and German Society of Internal Medicine
 
Membership of Editorial Boards, Advisory Boards, Distinctions, etc.
 
  • Editorial Board, World Journal of Hypertension, since 2012
  • Editorial Board, International Journal of Cardiology: Metabolic and Endocrine, since 2012
  • Board Member, Heart Failure Association of the European Society of Cardiology, since 2010
  • Editorial Board, Circulation, 1998-2003
  • Editorial Board, Journal of Molecular and Cellular Cardiology (1993 – 1998 and 2004-2007)
  • Scientific Committee ‘Archives of Cardiovascular Medicine’ (since 2007)
  • Council member, European Section of the International Society for Heart Research (1998-2004)
  • Member and elected Fellow, Society of Cardiac Angiography and Interventions since 1998
  • Founding Chairman, Working Group on Cardiovascular Molecular Biology and Gene Therapy of the German Society of Cardiology (1993-1995)
  • Co-chairman, working group “Clinical Pharmacology” of the German Society of Cardiology (1999-2001)
  • Reviewer (Chair) and site visitor for 250 million Euros ‘Integrated Treatment and Research Centres’, German Government (ongoing) and German University ‘Excellence Initiative (1.9 billion Euros)
  • Regular reviewer for all major European funding agencies as well as international journals
  • Distinguished Visiting Professor, Natl. University of Singapore, from 11/2007 and offer to head ‘Cardiovascular Research Institute’ in Singapore

Qualifications

 Scientific training with M.P. Dierich, Institute of Immunology, Mainz, Germany (MD thesis on complement receptors), W. Siegenthaler and W. Vetter, Dep. of Medicine, University Hospital, Zurich, Switzerland (molecular mechanisms of hypertensive heart disease and early atherosclerosis), E. Carafoli, Institute of Biochemistry, Federal Institute of Technology, Zurich, Switzerland (calcium transport in the heart), and R.S. Williams, Cardiovascular Division, Dep. of Medicine, Duke University, Durham, NC (molecular biology of signal transduction in cardiac hypertrophy and failure).

Role

  • Vice President for Research, University of Luxembourg
  • Chair of Medicine/Cardiology, University of Manchester (since 08/2001), joint appointment with the University of Luxembourg
  • Present research: My research group consists of 25 medical and PhD scientists and technicians and is committed to a translational (i.e. bench to bedside) approach in heart failure research. We perform molecular investigations using state-of-the-art transgenic, knock-out and haemodynamic technology and clinical trials. We also apply novel technology to clinical problems (e.g. metabolomic studies in heart failure)
  • I am also tasked with a feasibility study for establishing a Medical School in the Grand Duchy of Luxembourg