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Dr Annie Yarwood (PhD) - publications

List of publications


  • Hinks, A., Bowes, J., Cobb, J., Ainsworth, H. C., Marion, M. C., Comeau, M. E., ... Thomson, W. (2017). Fine-mapping the MHC locus in juvenile idiopathic arthritis (JIA) reveals genetic heterogeneity corresponding to distinct adult inflammatory arthritic diseases.Annals of the Rheumatic Diseases. DOI: 10.1136/annrheumdis-2016-210025. Publication link: fd9f6e13-a22b-4949-a75b-9566207b5443


  • Yarwood, A., Viatte, S., Okada, Y., Plenge, R., Yamamoto, K., BRAGGSS, ... Eyre, S. (2016). Loci associated with N-glycosylation of human IgG are not associated with rheumatoid arthritis: A Mendelian randomisation study.Annals of the Rheumatic Diseases, 75(1), 317-20. DOI: 10.1136/annrheumdis-2014-207210. Publication link: f39db358-92a0-480d-9c12-58d39222cb06
  • Yarwood, A., Huizinga, T. W., & Worthington, J. (2016). The genetics of rheumatoid arthritis: risk and protection in different stages of the evolution of RA. Rheumatology (Print), 55(2), 199-209. . Publication link: 23aaec46-eac1-43a8-b2e1-c01bdac6760f
  • Mcgovern, A., Schoenfelder, S., Martin, P., Massey, J., Duffus, K., Plant, D., ... Orozco, G. (2016). Capture Hi-C identifies a novel causal gene, IL20RA, in the pan-autoimmune genetic susceptibility region 6q23. Genome Biology, [212]. DOI: 10.1186/s13059-016-1078-x. Publication link: 12d9bfcf-12c8-45e3-9ba6-c81fbd5f444c
  • Martin, P., Mcgovern, A., Massey, J., Schoenfelder, S., Duffus, K., Yarwood, A., ... Orozco, G. (2016). Identifying Causal Genes at the Multiple Sclerosis Associated Region 6q23 Using Capture Hi-C. PLoS ONE, 11(11), [ e0166923]. DOI: 10.1371/journal.pone.0166923. Publication link: 4a694ff6-b1db-420c-99d8-b19497948d8c
  • Yarwood, A., Eyre, S., & Worthington, J. (2016). Genetic susceptibility to rheumatoid arthritis and its implications for novel drug discovery.Expert Opinion on Drug Discovery, 11(8), 805-813. DOI: 10.1080/17460441.2016.1195366. Publication link: 896d6734-35b3-4f67-8f8d-2f9312d40543
  • Wei, W., Bowes, J., Plant, D., Viatte, S., Yarwood, A., Massey, J., ... Eyre, S. (2016). Major histocompatibility complex harbors widespread genotypic variability of non-additive risk of rheumatoid arthritis including epistasis. Scientific Reports, 6, [25014]. DOI: 10.1038/srep25014. Publication link: 70c6b9a5-135b-4a46-be16-f435a0c466e2


  • Viatte, S., Plant, D., Han, B., Fu, B., Yarwood, A., Thomson, W., ... Barton, A. (2015). Association of HLA-DRB1 haplotypes with rheumatoid arthritis severity, mortality, and treatment response.JAMA, 313(16), 1645-1656. DOI: 10.1001/jama.2015.3435. Publication link: b882366e-0899-4461-9fbe-e64430a95f28 | PubMed:25919528
  • Yarwood, A., Han, B., Raychaudhuri, S., Bowes, J., Lunt, M., Pappas, D. A., ... Eyre, S. (2015). A weighted genetic risk score using all known susceptibility variants to estimate rheumatoid arthritis risk. Annals of the Rheumatic Diseases, 74(1), 170-176. DOI: 10.1136/annrheumdis-2013-204133. Publication link: e1cf45d5-af36-4757-afbd-7b1cbd3cde8d | PubMed:24092415
  • Martin, P., Mcgovern, A., Orozco, G., Duffus, K., Yarwood, A., Schoenfelder, S., ... Eyre, S. (2015). Capture Hi-C reveals novel candidate genes and complex long-range interactions with related autoimmune risk loci.Nature communications, 6, [10069]. DOI: 10.1038/ncomms10069. Publication link: 0d9a67a2-39d4-4fd1-a442-20b62d916fdf
  • Smith, S. L., Eyre, S., Yarwood, A., Hyrich, K. L., Morgan, A. W., Wilson, A. G., ... Barton, A. (2015). Investigating CD11c expression as a potential genomic biomarker of response to TNF inhibitor biologics in whole blood rheumatoid arthritis samples. Arthritis Research & Therapy (Print), 17, 359. DOI: 10.1186/s13075-015-0868-y. Publication link: 4c8f3f0a-e9a3-4787-8412-0ba442d571f0


  • Yarwood, A., Viatte, S., Plant, D., Morgan, A. W., Isaacs, J., Wilson, A. G., ... Barton, A. (2014). Testing the role of vitamin D in response to antitumour necrosis factor α therapy in a UK cohort: A Mendelian randomisation approach. Annals of the Rheumatic Diseases, 73(5), 938-940. DOI: 10.1136/annrheumdis-2013-204443. Publication link: b9655eac-b757-4f30-93a2-677429d9aa74 | PubMed:24323394
  • Viatte, S., Yarwood, A., McAllister, K., Al-Mudhaffer, S., Fu, B., Flynn, E., ... Duffus, K. (2014). The role of genetic polymorphisms regulating vitamin D levels in rheumatoid arthritis outcome: A Mendelian randomisation approach. Annals of the Rheumatic Diseases, 73(7), 1430-1433. DOI: 10.1136/annrheumdis-2013-204972. Publication link: baeae829-7410-464d-80c6-0762bb078036 | PubMed:24651622


  • McAllister, K., Yarwood, A., Bowes, J., Orozco, G., Viatte, S., Diogo, D., ... Eyre, S. (2013). Brief report: Identification of BACH2 and RAD51B as rheumatoid arthritis susceptibility loci in a meta-analysis of genome-wide data. Arthritis and Rheumatism, 65(12), 3058-3062. DOI: 10.1002/art.38183. Publication link: 83494893-5a06-44fb-841f-1f1a429f8bd9 | PubMed:24022229
  • Yarwood, A., Martin, P., Bowes, J., Lunt, M., Worthington, J., Barton, A., & Eyre, S. (2013). Enrichment of vitamin D response elements in RA-associated loci supports a role for vitamin D in the pathogenesis of RA. Genes and Immunity, 14(5), 325-329. DOI: 10.1038/gene.2013.23. Publication link: 6c9a5dea-6dc8-47f8-aa8f-cd977107930d | PubMed:23636220


  • McClure, A., Lunt, M., Eyre, S., Ke, X., Thomson, W., Hinks, A., ... Consortium, B. I. R. A. C. (2009). Investigating the viability of genetic screening/testing for RA susceptibility using combinations of five confirmed risk loci.Rheumatology, 48(11), 1369-1374. DOI: 10.1093/rheumatology/kep272. Publication link: faa78c27-a4d9-4a1b-adfd-6722849bbe68 | PubMed:19741008