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Dr Kirk Siddals - publications

List of publications


  • Forbes, K., Shah, V. K., Siddals, K., Gibson, J. M., Aplin, J. D., & Westwood, M. (2015). Statins inhibit insulin-like growth factor action in first trimester placenta by altering insulin-like growth factor 1 receptor glycosylation. Molecular human reproduction, 21(1), 105-114. DOI: 10.1093/molehr/gau093. Publication link: f38ebd38-5ec5-4b96-9753-849816c78e39 | PubMed:25304981


  • Westwood, M., Tajbakhsh, S. H., Siddals, K. W., Whatmore, A. J., & Clayton, P. E. (2011). Reduced pericellular sensitivity to IGF-I in fibroblasts from girls with Turner syndrome: A mechanism to impair clinical responses to GH. Pediatric Research, 70(1), 25-30. DOI: 10.1203/PDR.0b013e31821b570b. Publication link: a2808aee-5b60-483c-8240-785a422a4d24 | PubMed:21430600
  • Siddals, K., Siddals, K. W., Allen, J., Sinha, S., Canfield, A. E., Kalra, P. A., & Martin Gibson, J. (2011). Apposite insulin-like growth factor (IGF) receptor glycosylation is critical to the maintenance of vascular smooth muscle phenotype in the presence of factors promoting osteogenic differentiation and mineralization. Journal of Biological Chemistry, 286(19), 16623-16630. DOI: 10.1074/jbc.M110.202929. Publication link: 1f060728-befb-48ca-bba4-3d85eb512fda | PubMed:21454560



  • Heald, A. H., Kaushal, K., Siddals, K. W., Rudenski, A. S., Anderson, S. G., & Gibson, J. M. (2006). Insulin-like growth factor binding protein-2 (IGFBP-2) is a marker for the metabolic syndrome. Experimental and Clinical Endocrinology and Diabetes, 114(7), 371-376. DOI: 10.1055/s-2006-924320. Publication link: 5195bfc0-6c19-497b-83ac-a0f53fa53650 | PubMed:16915540


  • Mishra, M., Durrington, P., Mackness, M., Siddals, K. W., Kaushal, K., Davies, R., ... Ray, D. W. (2005). The effect of atorvastatin on serum lipoproteins in acromegaly. Clinical Endocrinology, 62(6), 650-655. DOI: 10.1111/j.1365-2265.2005.02273.x. Publication link: 94d4716b-dda3-47bb-9f22-39373fa23b9f
  • Heald, A. H., Sharma, R., Anderson, S. G., Vyas, A., Siddals, K., Patel, J., ... Cruickshank, J. K. (2005). Dietary intake and the insulin-like growth factor system: effects of migration in two related populations in India and Britain with markedly different dietary intake. Public Health Nutrition, 8(6), 620-7. DOI: 10.1079/PHN2005729. Publication link: 3715c270-eae1-4ab4-a2a8-a9ed537be4a9 | PubMed:16236191
  • Heald, A. H., Anderson, S. G., Vyas, A., Siddals, K., Patel, J., Yates, A. P., ... Cruickshank, J. K. (2005). Marked differences in the IGF system that are associated with migration in comparable populations of Gujaratis living in Sandwell, UK, and Gujarat, India. Diabetologia, 48(9), 1756-1765. DOI: 10.1007/s00125-005-1871-7. Publication link: ffd98568-b128-449c-8ce3-25a9aa66024c


  • Heald, A. H., Golding, C., Sharma, R., Siddals, K., Kirk, S., Lawton, C., ... Cade, J. E. (2004). A substitution model of dietary manipulation is an effective means of optimising lipid profile, reducing C-reactive protein and increasing insulin-like growth factor-1. British Journal of Nutrition, 92(5), 809-818. DOI: 10.1079/BJN20041262. Publication link: 4f00fc44-1bc0-47d2-ba60-5dd9185de991
  • Siddals, K. W., Gibson, J. M., Marshman, E., & Westwood, M. (2004). Abrogation of insulin-like growth factor-I (IGF-I) and insulin action by mevalonic acid depletion: synergy between protein prenylation and recep glycosylation pathways.Journal of Biological Chemistry, 279(37). . Publication link: 6c21476b-97c3-4131-9701-3152178c0193
  • Kaushal, K., Heald, A. H., Siddals, K. W., Sandhu, M. S., Dunger, D. B., Gibson, J. M., & Wareham, N. J. (2004). The impact of abnormalities in IGF and inflammatory systems on the metabolic syndrome. Diabetes Care, 27(11), 2682-2688. DOI: 10.2337/diacare.27.11.2682. Publication link: d380725f-5aa7-4d08-a918-2097014c5aed


  • Heald, A. H., Siddals, K. W., Fraser, W., Taylor, W., Kaushal, K., Morris, J., ... Martin Gibson, J. (2002). Low circulating levels of insulin-like growth factor binding protein-1 (IGFBP-1) are closely associated with the presence of macrovascular disease and hypertension in type 2 diabetes. Diabetes, 51(8), 2629-2636. DOI: 10.2337/diabetes.51.8.2629. Publication link: 624e2db3-fea2-44f4-9895-9f60a31708f6