Course unit details:
Integrated Spectroscopy and Separations
Unit code | CHEM61201 |
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Credit rating | 15 |
Unit level | FHEQ level 7 – master's degree or fourth year of an integrated master's degree |
Teaching period(s) | Semester 1 |
Available as a free choice unit? | No |
Overview
Molecular spectroscopy, chromatography and mass spectrometry are fundamental to chemical analysis and are important tools in all areas of chemistry. In this module, further principles and applications of some of the most common techniques will be presented. The primary objective of the module is to present an integrated, coherent discussion of chemical identification using chromatography and a combination of spectra, as practiced in a modern synthetic and analytical chemical laboratories and to put this into practice in a chemical laboratory environment working under relevant COSHH and risk assessment protocols.
Aims
The unit aims to:
- Explore aspects of the theory of molecular spectroscopy, mass spectrometry and chromatography, as applied in analytical chemistry labs to small molecules.
- Practice the interpretation of spectra and chromatograms, and to integrate data from multiple methods to identify unknown molecules.
- Practice multispectral interpretation in a supportive, workshop setting in order to develop analytical chemistry skills for practical labs and projects.
- Undertake laboratory work across a range of applications involving safety assessments, synthetic preparations, separation and analysis by relevant spectroscopic methods.
Learning outcomes
A full list of the Intended Learning Outcomes is present on the course's Blackboard page.
At the end of this module, students should be able to;
- Explain the principles of operation of NMR and IR spectroscopy, mass spectrometry and chromatography, and describe the chemical information that can be provided by each method.
- Describe and explain the ways in which NMR and IR spectroscopy, mass spectrometry and chromatography are used by practical chemists for quantitative and qualitative analysis;
- Apply knowledge of each of the methods to unseen examples, both isolated techniques and in conjunction, to determine elements of chemical composition;
- Apply knowledge of each of the methods to devise a suitable analytical strategy for unseen examples, by selecting appropriate methods of quantitative and qualitative chemical analysis.
Teaching and learning methods
Transferable skills and personal qualities
- Accessing and using databases of spectral information
- Systematic approaches to problem-solving using a range of data sources
- Working in small groups
- Safe planning experiments
- Time management
- Reporting Skills
- Analytical Skills
Assessment methods
Method | Weight |
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Written exam | 56% |
Written assignment (inc essay) | 30% |
Set exercise | 14% |
Feedback methods
Oral and written feedback will be given through workshops, tutorials and laboratory write-up feedback. There will also be formative self-assessment exercises on Blackboard, and using software packages (WINTORG and TORGANAL) on the university computer clusters. In-lab feedback on technique.
Feedback on the exam performance will also be provided in line with Departmental policy.
Recommended reading
The following textbooks are recommended reading and reference materials.
General (including MS and Chromatography)
- D. C. Harris, Quantitative Chemical Analysis, 8th or 9th Edn., W. H. Freeman, 2010 or 2015.
- D. L. Andrews, Encyclopaedia of Applied Spectroscopy, Wiley, 2009.
- D. H. Williams, I. Fleming, Spectroscopic Methods in Organic Chemistry, 6th Edn., McGraw-Hill, 2007.
NMR
- T. D. W. Claridge, High-Resolution NMR Techniques in Organic Chemistry, 2nd Edn., Elsevier, 2016.
- P.J. Hore, Nuclear Magnetic Resonance (Oxford Chemistry Primer Series), 2nd Edn., Oxford University Press, 2015.
- J. W. Akitt, B. E. Mann, NMR and Chemistry: An introduction to modern NMR spectroscopy, 4th Edn., CRC Press, 2000.
Laboratory
- C. E. Housecroft and A. G. Sharp, Inorganic Chemistry, 4th edition.
Study hours
Scheduled activity hours | |
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Assessment written exam | 2 |
Lectures | 21 |
Practical classes & workshops | 35 |
Tutorials | 3 |
Independent study hours | |
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Independent study | 89 |
Teaching staff
Staff member | Role |
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Gareth Morris | Unit coordinator |