New Brain Health Centre marks a step change in dementia diagnosis and prevention

A UK-first brain health clinic that is set to transform how dementia is diagnosed, slowed down or prevented has launched in central Manchester. Designed as a scalable model which could be adopted nationwide, it represents a major step forward in reshaping the UK’s approach to brain health.

Around one million people are living with dementia in the UK, yet more than a third do not have a diagnosis. Dementia risk is shaped by a mix of health, lifestyle and environmental factors, but there are positive steps people can take to reduce their risk.

The Manchester Brain Health Centre (MBHC) has been spearheaded by Alzheimer’s Society in partnership with Manchester University NHS Foundation Trust, Greater Manchester Mental Health NHS Foundation Trust, The Geoffrey Jefferson Brain Research Centre at The University of Manchester and supported by NHS Greater Manchester.

MBHC is a unique joined-up, single service bringing together psychiatrists, vascular specialists, clinical academics, and a multidisciplinary team to identify and support people at the earliest stages of memory loss. People will benefit from advanced diagnostic techniques such as MRI scans, lumbar punctures, heart health checks, and behavioural assessments, delivering an earlier and accurate diagnosis. This approach will also help identify underlying risk factors and inform the most effective treatment and support plan for individuals.

People who meet the requirements for the MBHC will be identified through existing memory assessment services and referred directly. Those who take part in the two-year pilot in central Manchester will also be given the chance, if they are eligible, to take part in research and clinical trials.

Alzheimer’s Society Brain Health Advisers will work alongside NHS clinicians to offer personalised support, guidance and information to people with mild cognitive impairment (MCI), an early stage of memory and thinking changes, or dementia, as well as to anyone looking to improve their brain health through achievable lifestyle and health changes.

Michelle Dyson CB, Alzheimer’s Society Chief Executive Officer, said: “Dementia is the UK’s biggest killer, but it is not an inevitable part of ageing. Nearly half (45%) of dementia cases worldwide could be prevented or delayed by addressing health and lifestyle factors, throughout our lives, like high blood pressure.

“If we can identify people early enough, we can significantly improve their brain health and help put the brakes on dementia. The Manchester Brain Health Centre really is changing the game, and we are proud to be a partner. This model could be replicated in other regions, transforming the future for thousands of people at risk of dementia or in the early stages of memory loss.”

Professor Adam Greenstein, Consultant Geriatrician at Manchester University NHS Foundation Trust, Clinical Scientist at University of Manchester and Alzheimer’s Society Ambassador, said: “The Manchester Brain Health Centre is a game-changing approach which brings together partners who believe that greater collaboration can help diagnose more people at an earlier stage and improve health outcomes. We are combining clinical and research expertise to identify people earlier, address risk factors such as high blood pressure, and support patients to live better for longer.

This is an innovative step towards a proactive approach to brain health, and we are creating a model which we believe could be adopted more widely. Through this pilot, we will be generating the evidence to support future service collaboration and development by clinical, research and academic teams across the country.”

Dr Ross Dunne, Consultant Later Life Psychiatrist and Dementia Research Lead at Greater Manchester Mental Health NHS Foundation Trust, said: “The Manchester Brain Health Centre is crucial to advancing our understanding and treatment of the diseases that cause dementia. Right now, the system is not set up for people when memory and thinking problems first appear. That is exactly when early diagnosis and treatment could have the greatest impact.

“We want the UK to be the best place in the world to get an early and accurate diagnosis. We can be a world leader in the research that will change the future of dementia. Together with our partners in Greater Manchester and Alzheimer's Society, our aim is to develop a model for brain health clinics nationwide.”

The Manchester Brain Health Centre’s pilot clinic is hosted at the National Institute for Health and Care Research (NIHR) Clinical Research Facility (CRF): Manchester at Manchester Royal Infirmary.

• The Manchester Brain Health Centre reflects The University of Manchester's commitment through its Challenge Accepted campaign to bring together research, healthcare and communities to address some of society's most pressing challenges, including improving health outcomes and healthy ageing.
• If you’re worried about yourself, or someone close to you, then Alzheimer’s Society’s symptom checklist can help you start a conversation with a GP. Visit alzheimers.org.uk/checklist or call their Dementia Support Line on 0333 150 3456.