Dr Wenhua Wei - personal details
Role: Lecturer in Statistical Genetics
Tel: +44 (0)161 2755639
I am a computational statistical geneticist working across the human and livestock animal sectors. Originally trained in China as a quantitative geneticist and sheep scientist, I worked multiple projects in the country for seven years, including a challenging but exciting project aiming to initiate sheep industry in the warm and humid hill countries in the south to help farmers out of poverty. I moved to New Zealand to pursue my PhD in computational animal genetics in 1998. Attributing to my good performance in a series of computing courses in parallel, I was offered a summer school lecturer and consecutively a software engineer positions immediately after my PhD work in 2002. After adequate computing expereince, I resumed my academic career in 2004 as a postdoctoral fellow in agro-ecosystem modelling.
I joined University of Edinburgh in 2005. Since then I have been trained in complex trait genetics in Professor Chris Haley's lab for eight years, first as a postdoctoral fellow, then a tenured statistical bioinformatician in 2007 (funded by BBSRC) and then an MRC senior investigator scientist in 2009. I took a Lecturer position in University of Manchester in 2013. Most of my work so far has been focusing on understanding the role of gene-gene interactions in the genetic regulation of complex traits. I have led a few small research grants and published software tools (i.e. BiForce, EpiGPU and GridQTL) and a series of papers examining key issues in high-throughput studying gene interactions. While continuously strengthening the expertises in studying gene interactions, I will concentrate on comprehensive and integrative approaches to study the genetic architecture and regulation mechanisms underlying autoimmune diseases and better our understanding of disease heterogeneity.
Memberships of Committees and Professional Bodies
Genetics Society UK
European Scociety of Human Genetics
PhD in Animal Genetics and Applied Computing (Oct 2003), Lincoln University, New Zealand
Graduate Diploma in Applied Computing (Jun 2001), Lincoln University, New Zealand
MSc in Animal Breeding and Genetics (Jul 1991), Huazhong Agricultural University, China
BSc in Animal Husbandry (Jul 1988), Huazhong Agricultural University, China
I will help develop a statistical genetics and bioinformatics research group within the Centre for Musculoskeletal Research and provide analysis support to various research projects related to the Centre. In addition, I will continue developing my research interests in dissecting complex diseases. I will also work closely with Professor Soumya Raychaudhuri to strengthen the existing link with Harvard Medical School and the Broad Institute.