MSc Clinical Biochemistry

This unit will equip students with a detailed understanding of the biochemical consequences of common disorders of the major endocrine glands (adrenal medulla, endocrine pancreas, pituitary gland, etc). This will include a comprehensive appreciation of the key role hormones play in the regulation of tissue/organ function and whole body homeostasis. This unit will also supply students with the knowledge of the methodologies available to monitor endocrine function and the understanding and skills to enable them to evaluate and interpret data obtained using said technologies.

This unit employs a range of teaching and learning approaches including lectures, tutorials, case studies/presentations, problem based learning and data analysis and interpretation exercises. Mobile Learning (M-learning) is also used to provide interactive tutorials and formative assessment.

•    Explain, compare and contrast the synthesis, regulation, metabolism and modes of action of hormones in health and disease.
•    Apply integrative knowledge of the use of laboratory testing, including dynamic function tests to differentiate and diagnose endocrine disorders.
•    Describe how to derive appropriate reference intervals for different patient groups, the importance of biological variation and interference when interpreting hormone results.
•    Critically evaluate the clinical and laboratory investigation strategies of a wide range of endocrine disorders.
•    Critically evaluate the design, operation and performance of the range of methods used in the measurement of hormones.
•    Explain the causes, classification and investigation of diabetes mellitus using the underpinning evidence base.
•    Critically evaluate the design, operation and performance of the range of laboratory and point-of-care methods used in the screening, diagnosis and monitoring of diabetes mellitus.

•    To critically analyse and interpret data obtained from the biochemical investigation of endocrine function. 
•    To critically analyse and interpret data relating to the diagnosis and monitoring of diabetes mellitus.
•    To critically compare, contrast and evaluate the performance of new and established analytical technologies for the assessment of endocrine function and the investigation and diagnosis of diabetes mellitus.
•    Employ critical thinking and reflection to formulate appropriate strategies for the diagnosis of common endocrine disorders including diabetes mellitus based on the biochemical investigation of endocrine function.
•    To select appropriate statistically analyses to examine data obtained from either lab based or clinical studies.

•    Retrieve, manage and collate information from primary and secondary sources.
•    Present information clearly in the form of verbal and written reports.
•    Communicate complex ideas and arguments in a clear and concise and effective manner.
•    Manage personal workload and objectives to achieve optimal personal performance.
•    Work effectively either as an individual or part of a team.

•    Effectively utilise a range of information sources including information technology / health informatics.
•    Demonstrate capacity for self-learning and independent thinking and to utilise problem solving skills. 
•    Demonstrate effective communication skills (verbal and written). 
•    Be able to set priorities and link these with effective time management. 
•    Critically evaluate their personal performance both as an individual and within a team.
•    Demonstrate skills in working collegiately and effectively with others as a member of a team.
 

MCQs/short answer exam: 80%

Assignment: 20%
 

Formative case presentations, data interpretation exercises, interactive tutorial using mobile technology and practice exam questions.