
- UCAS course code
- C701
- UCAS institution code
- M20
BSc Biochemistry with Industrial/Professional Experience
Year of entry: 2021
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Course unit details:
Drugs: From Molecules to Man
Unit code | BIOL10822 |
---|---|
Credit rating | 10 |
Unit level | Level 1 |
Teaching period(s) | Semester 2 |
Offered by | School of Biological Sciences |
Available as a free choice unit? | No |
Overview
This unit introduces pharmacology - the science of drugs: their preparation, properties, uses and effects. You will learn about the molecular interactions of drugs with their targets in the body, focusing on the actions of the drugs acting on the cardiorespiratory system which treat conditions such as angina and asthma.
Pre/co-requisites
Unit title | Unit code | Requirement type | Description |
---|---|---|---|
Body Systems | BIOL10811 | Co-Requisite | Recommended |
Aims
To introduce the major concepts underpinning pharmacology. To describe the main molecular mechanisms of action of some important classes of drugs acting on the cardiorespiratory system and relate these mechanisms to their cellular, tissue, organ and whole animal effects.
Learning outcomes
To understand: the molecular targets for drugs and examples of drugs acting at several target types; the basic concepts of drug receptor interactions; the importance of drug structure in their ability to interact with their targets; the mechanisms of the major drug classes used to treat hypertension, angina, cardiac failure, cardiac dysrhythmias and asthma.
Syllabus
Introduction to pharmacology: History and scope of pharmacology. How drugs are discovered.
Introduction to drug targets: Structure, function and cellular location of ligand-gated channels, voltage gated channels, enzymes, nuclear hormone receptors, transporters and pumps, G-protein coupled receptors.
Nature of drug receptor interactions: Agonists, antagonists and partial agonists, efficacy, drug structures, pharmacophores and selectivity. Concentration-response relationships. Gaddum, Schild analysis.
Role of specialized disciplines within pharmacology: toxins from animal and plant sources, molecular and cellular techniques in pharmacology, discovering the structure of G protein coupled receptors.
Drugs acting on the cardiovascular/respiratory systems: Antihypertensive drugs, antidysrhythmic drugs, drugs used to treat angina and cardiac failure, lipid lowering drugs, drugs used to treat and prevent thrombosis, drugs used to treat asthma.
Employability skills
- Analytical skills
- Data handling ePBL
- Problem solving
- Data handling ePBL
- Other
- Handling complex data, time management
Assessment methods
Method | Weight |
---|---|
Other | 20% |
Written exam | 80% |
80% awarded for a one hour examination, which will include 40 MCQs, a series of numerical questions and one short note question (from a choice of three) in the semester 2 examination period, and 20% awarded for electronically marked exercises.
Feedback methods
Feedback will be provided via automated ePBL responses; mid-semester mini exam; post-examination guidance (if requested).
Recommended reading
Title below is also available as an eBook via JRUL website.
Recommended Reading
- Ritter et al., Rang & Dale's Pharmacology (9th Edition) 2019 Churchill Livingstone Available as an eBook via JRUL website.
Study hours
Scheduled activity hours | |
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Assessment written exam | 1 |
Lectures | 20 |
Independent study hours | |
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Independent study | 79 |
Teaching staff
Staff member | Role |
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Richard Prince | Unit coordinator |