- UCAS course code
- B9R9
- UCAS institution code
- M20
Bachelor of Science (BSc)
BSc Biomedical Sciences with a Modern Language
- Typical A-level offer: AAA-AAB including specific subjects
- Typical contextual A-level offer: AAB-ABC including specific subjects
- UK refugee/care-experienced offer: ABB-ABC including specific subjects
- Typical International Baccalaureate offer: 35 points overall with 6, 6, 5 at HL, including specific requirements
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Course unit details:
Immune Response & Disease
| Unit code | BIOL31802 |
|---|---|
| Credit rating | 10 |
| Unit level | Level 3 |
| Teaching period(s) | Semester 2 |
| Offered by | School of Biological Sciences |
| Available as a free choice unit? | No |
Overview
This Unit builds on the compulsory pre-requisite Advanced Immunology Unit (BIOL31371). Having learnt about how the immune system functions to sense and mount appropriate protective responses to different challenges in a manner so as to protect and maintain a healthy body last semester, you will now look at ways in which this normal function of the immune system can go wrong, why this results in disease, and how knowledge of normal and disease mechanisms can be used to inform corrective intervention. The Unit is organised as themed weeks, with each week dedicated to a different disease situation resulting from the actions of inappropriate immunity or immune dysfunction.
Pre/co-requisites
| Unit title | Unit code | Requirement type | Description |
|---|---|---|---|
| Immunology | BIOL21242 | Pre-Requisite | Compulsory |
| Advanced Immunology | BIOL31371 | Pre-Requisite | Compulsory |
Aims
• To use knowledge of normal protective immune function to explain processes of disease in named situations involving inappropriate or dysfunctional immunity.
• To apply knowledge of the process of disease to explain current approaches to clinical intervention in the examples of immune-related disease being considered.
• To consider examples of contemporary experimental approaches aiming to manipulate the immune system in the context of immune-related disease for improved therapeutic intervention in the future.
Learning outcomes
By the end of this Unit you should be able to;
• use your understanding of normal immune function to explain mechanisms of disease in named situations of inappropriate immunity or immune dysfunction studied in the Unit
• critically evaluate the rationale for current therapeutic intervention in relation to knowledge of immune dysfunction in such situations
• discuss, using examples, how knowledge of disease mechanism is informing experimental approaches to improved therapeutic intervention in the future.
Syllabus
This Unit builds on the compulsory pre-requisite Advanced Immunology Unit (BIOL31371). Having learnt about how the immune system functions to sense and mount appropriate responses to different challenges in a manner so as to protect and maintain a healthy body last semester, you will now look at ways in which this normal function of the immune system can go wrong, why this results in disease, and how knowledge of normal and disease mechanisms can be used to inform corrective intervention. The Unit will be organised as five themes, with each theme dedicated to a different disease situation resulting from the actions of inappropriate immunity or immune dysfunction.
Recent themes in the Unit have been autoimmunity, immune dysregulation in the brain, lung diseases, cancer, and inflammatory bowel disease. Themes are reviewed regularly to ensure they are reflective of current trends in the field and can change from year to year. For each theme, you will establish the underlying mechanism of disrupted immunity and how this results in disease, how this understanding has informed current clinical interventions and how it is driving experimental approaches toward improved therapeutic intervention in the future.
Employability skills
- Group/team working
- Group collaboration through discussion on the online community discussion forum.
- Research
- Engaging with primary literature; analysing and discussing scientific concepts
- Written communication
- Discussion on the online community discussion forum; essay-based summative exam.
Assessment methods
| Method | Weight |
|---|---|
| Written exam | 100% |
Invigilated exam (2 hours)
One essay from a choice of 5, worth 70%, plus MCQ, worth 30%.
Feedback methods
- Online ’Community Discussion Forum’, incorporating anonymous submission and discussion, and monitored by staff up to the Unit exam.
- Interactive class discussion using past exam questions to challenge knowledge and interrogate course material.
- Compiled examiner reports accompanying provided past papers.
- Post-exam reflection informed by examiner comments on scripts provided on request.
Recommended reading
Recommended: Kuby Immunology (8th edition, 2018), written by Stranford, Owen, Jones and Punt (MacMillan Education),
Optional: Janeway’s Immunobiology, 10th Edition (2022), written by Murphy and Weaver (Garland Scientific).
Optional: The Immune System (5th edition, 2021), written by Peter Parham (Norton & Co).
Optional: Roitt’s Essential Immunology (13th edition, 2017), written by Delves, Martin, Burton and Roitt (Wiley-Blackwell).
Immunology is a fast-moving field. Further reviews, original articles and websites will be provided in lectures.
Study hours
| Scheduled activity hours | |
|---|---|
| Assessment written exam | 2 |
| Lectures | 15 |
| Practical classes & workshops | 3 |
| Independent study hours | |
|---|---|
| Independent study | 80 |
Teaching staff
| Staff member | Role |
|---|---|
| Kathleen Nolan | Unit coordinator |
Fees and funding
Fees
Tuition fees for home students commencing their studies in September 2027 will be £10,050 per annum. Tuition fees for international students will be £38,000 per annum.
For general information please see the undergraduate finance pages.
Policy on additional costs
All students should normally be able to complete their programme of study without incurring additional study costs over and above the tuition fee for that programme. Any unavoidable additional compulsory costs totalling more than 1% of the annual home undergraduate fee per annum, regardless of whether the programme in question is undergraduate or postgraduate taught, will be made clear to you at the point of application. Further information can be found in the University's Policy on additional costs incurred by students on undergraduate and postgraduate taught programmes (PDF document, 91KB).
Scholarships/sponsorships
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The University of Manchester is regulated by the Office for Students (OfS). The OfS aims to help students succeed in Higher Education by ensuring they receive excellent information and guidance, get high quality education that prepares them for the future and by protecting their interests. More information can be found at the OfS website.
You can find regulations and policies relating to student life at The University of Manchester, including our Degree Regulations and Complaints Procedure, on our regulations website.
