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MChem Chemistry with Medicinal Chemistry / Course details
Year of entry: 2023
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Course unit details:
The Big Killers
|Unit level||Level 5|
|Teaching period(s)||Semester 2|
|Available as a free choice unit?||No|
Lectures from staff from the Division of Pharmacy and Optometry and School of Chemistry will discuss the “big killers”.
Part 1 Dr Jill Barber (Division of Pharmacy and Optometry) (11 lectures)
Targets for antibacterial chemotherapy and the discovery and development of antibacterial agents. Antibacterial drug resistance. The geography and status of protozoal disease. The discovery and development of antiprotozoal, especially antimalarial, drugs.
– coronary heart disease and stroke
Part 2 Dr John Gardiner (School of Chemistry) (5 lectures)
Targets for antiviral therapy and the discovery and development of antiviral agents. Nucleoside analogues (anti-HIV, anti-HSV), non-nucleoside RT inhibitors of HIV-RT, protease inhibitors and neuraminidase inhibitors as anti-influenza drugs.
Part 3 Dr Katie Finegan (Division of Pharmacy and Optometry) (3 lectures)
Molecular targets in cancer
By the end of this module you should be able to discuss:
- The major diseases worldwide and how they are treated
- The use of antibacterial drugs to treat TB and other bacterial illnesses
- The use of antiprotozoal drugs to treat malaria and other protozoal illnesses
- The use of antiviral drugs to treat HIV and other viral illnesses
- The use of anticancer drugs and the underlying biology of cancer
- The causes, prevention and treatment of cardiovascular disease
Knowledge and understanding
Students will appreciate the importance of poverty in premature death. The diseases of poverty and of excess will be discussed and students will understand the influence of geography on disease worldwide. Students should understand the prevention and treatment of bacterial disease (especially TB), protozoal disease (especially malaria), viral disease (especially AIDS), cancer and cardiovascular disease.
Students will understand the mechanism of action of several categories of antiviral agents.
Students will be able to match a disease with treatment and/or prevention
Transferable skills and personal qualities
Students with social consciences will appreciate the social responsibility aspects of the module, which maps onto the Social Responsibility section of the 2015 and 2020 agenda.
Each topic will be taught using lectures and there will be an assessed workshop.
Feedback is given following the workshop verbally. Detailed individual feedback is given following the course test using Smallvoice.
|Scheduled activity hours|
|Assessment written exam||2|
|Practical classes & workshops||2|
|Independent study hours|
|John Gardiner||Unit coordinator|
|Jill Barber||Unit coordinator|
|Katherine Finegan||Unit coordinator|